Trophoblasts
-
Subject Areas on Research
- A simple and robust fluorescent labeling method to quantify trophoblast fusion.
- A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance.
- Altered cyclic AMP-dependent human chorionic gonadotropin production in cultured human placental trophoblasts exposed to ethanol.
- Autophagy as a mechanism of antiviral defense at the maternal-fetal interface.
- Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2.
- Chemokine ligand and receptor expression in the pregnant uterus: reciprocal patterns in complementary cell subsets suggest functional roles.
- Chromosome 19 microRNAs exert antiviral activity independent from type III interferon signaling.
- Cigarette smoke-induced placental adrenomedullin expression and trophoblast cell invasion.
- Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration.
- Cytogenetics and mechanisms of spontaneous abortions: increased apoptosis and decreased cell proliferation in chromosomally abnormal villi.
- Cytokine expression by models of human trophoblast as assessed by a semiquantitative reverse transcription-polymerase chain reaction technique.
- Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism.
- Differential localization of placental extracellular superoxide dismutase as pregnancy progresses.
- Embryonic development of human transplantation antigens.
- Exposure to perfluorobutane sulfonate and perfluorooctanesulfonic acid disrupts the production of angiogenesis factors and stress responses in human placental syncytiotrophoblast.
- Expression and production of interleukin-10 by human trophoblast: relationship to pregnancy immunotolerance.
- Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines.
- Human placental trophoblasts confer viral resistance to recipient cells.
- Human trophoblasts confer resistance to viruses implicated in perinatal infection.
- In vitro development of inner cell masses isolated immunosurgically from mouse blastocysts. I. Inner cell masses from 3.5-day p.c. blastocysts incubated for 24 h before immunosurgery.
- In vitro development of inner cell masses isolated immunosurgically from mouse blastocysts. II. Inner cell masses from 3.5- to 4.0-day p.c. blastocysts.
- Infection-induced thrombin production: a potential novel mechanism for preterm premature rupture of membranes (PPROM).
- Inflammasome signaling in human placental trophoblasts regulates immune defense against Listeria monocytogenes infection.
- Innate immune defenses at the maternal-fetal interface.
- Intravillous eicosanoid compartmentalization and regulation of placental blood flow.
- Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity.
- Lipid raft- and SRC family kinase-dependent entry of coxsackievirus B into human placental trophoblasts.
- Localization of fibronectin, laminin-entactin, and entactin in Reichert's membrane by immunoelectron microscopy.
- Low-dose aspirin prevents LPS-induced preeclampsia-like phenotype via AQP-1 and the MAPK/ERK 1/2 pathway.
- Neem oil inhibits two-cell embryo development and trophectoderm attachment and proliferation in vitro.
- Perfluoroalkyl Substance Exposure and the BDNF Pathway in the Placental Trophoblast.
- Perfluorobutane sulfonate exposure disrupted human placental cytotrophoblast cell proliferation and invasion involving in dysregulating preeclampsia related genes.
- Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus.
- Site-specific silencing of regulatory elements as a mechanism of X inactivation.
- Stimulation of GCMa transcriptional activity by cyclic AMP/protein kinase A signaling is attributed to CBP-mediated acetylation of GCMa.
- TMEM16F phospholipid scramblase mediates trophoblast fusion and placental development.
- The Function of TrophomiRs and Other MicroRNAs in the Human Placenta.
- The Role of Congenital Cytomegalovirus Infection in Adverse Birth Outcomes: A Review of the Potential Mechanisms.
- The effect of cigarette smoke extract on trophoblast cell viability and migration: the role of adrenomedullin.
- The requirement of SUMO2/3 for SENP2 mediated extraembryonic and embryonic development.
- The role of trophoblastic microRNAs in placental viral infection.
- Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways.
- Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection.
- Unc-13 homolog D mediates an antiviral effect of the chromosome 19 microRNA cluster miR-517a.
- siRNA inhibition of aspartyl-asparaginyl β-hydroxylase expression impairs cell motility, Notch signaling, and fetal growth.
-
Keywords of People
- Hogan, Brigid L. M., George Barth Geller Distinguished Professor for Research in Molecular Biology, Cell Biology