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Subject Areas on Research
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A novel human endogenous retroviral protein inhibits cell-cell fusion.
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A possible coagulation-independent mechanism for pregnancy loss involving β(2) glycoprotein 1-dependent antiphospholipid antibodies and CD1d.
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A simple and robust fluorescent labeling method to quantify trophoblast fusion.
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A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance.
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African and Asian strains of Zika virus differ in their ability to infect and lyse primitive human placental trophoblast.
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Altered cyclic AMP-dependent human chorionic gonadotropin production in cultured human placental trophoblasts exposed to ethanol.
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Autophagy as a mechanism of antiviral defense at the maternal-fetal interface.
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Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2.
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Chemokine ligand and receptor expression in the pregnant uterus: reciprocal patterns in complementary cell subsets suggest functional roles.
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Chromosome 19 microRNAs exert antiviral activity independent from type III interferon signaling.
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Cigarette smoke-induced placental adrenomedullin expression and trophoblast cell invasion.
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Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration.
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Comparison of extravillous trophoblast cells derived from human embryonic stem cells and from first trimester human placentas.
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Comparison of syncytiotrophoblast generated from human embryonic stem cells and from term placentas.
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Complete and unidirectional conversion of human embryonic stem cells to trophoblast by BMP4.
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Could the Human Endogenous Retrovirus-Derived Syncytialization Inhibitor, Suppressyn, Limit Heterotypic Cell Fusion Events in the Decidua?
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Cytogenetics and mechanisms of spontaneous abortions: increased apoptosis and decreased cell proliferation in chromosomally abnormal villi.
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Cytokine expression by models of human trophoblast as assessed by a semiquantitative reverse transcription-polymerase chain reaction technique.
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Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism.
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Differential localization of placental extracellular superoxide dismutase as pregnancy progresses.
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Differentiation of trophoblast cells from human embryonic stem cells: to be or not to be?
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Early onset preeclampsia in a model for human placental trophoblast.
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Effects of Lipopolysaccharide on Human First Trimester Villous Cytotrophoblast Cell Function In Vitro.
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Embryonic development of human transplantation antigens.
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Enhanced HIF2α expression during human trophoblast differentiation into syncytiotrophoblast suppresses transcription of placental growth factor.
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Evidence for Differential Glycosylation of Trophoblast Cell Types.
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Exposure to perfluorobutane sulfonate and perfluorooctanesulfonic acid disrupts the production of angiogenesis factors and stress responses in human placental syncytiotrophoblast.
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Expression and production of interleukin-10 by human trophoblast: relationship to pregnancy immunotolerance.
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Expression of surface CD1d in the extravillous trophoblast cells of early gestational placenta is downregulated in a manner dependent on trophoblast differentiation.
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Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion.
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Heightened potency of human pluripotent stem cell lines created by transient BMP4 exposure.
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Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines.
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Human placental trophoblasts confer viral resistance to recipient cells.
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Human trophoblasts confer resistance to viruses implicated in perinatal infection.
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ITGA1 is upregulated in response to oxygen over time in a BMP4 model of trophoblast.
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Immune interactions at the maternal-fetal interface: a focus on antigen presentation.
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In vitro development of inner cell masses isolated immunosurgically from mouse blastocysts. I. Inner cell masses from 3.5-day p.c. blastocysts incubated for 24 h before immunosurgery.
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In vitro development of inner cell masses isolated immunosurgically from mouse blastocysts. II. Inner cell masses from 3.5- to 4.0-day p.c. blastocysts.
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Infection-induced thrombin production: a potential novel mechanism for preterm premature rupture of membranes (PPROM).
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Inflammasome signaling in human placental trophoblasts regulates immune defense against Listeria monocytogenes infection.
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Innate immune defenses at the maternal-fetal interface.
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Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface.
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Intravillous eicosanoid compartmentalization and regulation of placental blood flow.
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Involvement of the HERV-derived cell-fusion inhibitor, suppressyn, in the fusion defects characteristic of the trisomy 21 placenta.
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Is SARS-CoV-2 Infection a Risk Factor for Early Pregnancy Loss? ACE2 and TMPRSS2 Coexpression and Persistent Replicative Infection in Primitive Trophoblast.
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Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity.
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Isolation, purification and in vitro differentiation of cytotrophoblast cells from human term placenta.
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Lipid raft- and SRC family kinase-dependent entry of coxsackievirus B into human placental trophoblasts.
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Localization of fibronectin, laminin-entactin, and entactin in Reichert's membrane by immunoelectron microscopy.
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Low-dose aspirin prevents LPS-induced preeclampsia-like phenotype via AQP-1 and the MAPK/ERK 1/2 pathway.
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Modeling human peri-implantation placental development and function†.
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Neem oil inhibits two-cell embryo development and trophectoderm attachment and proliferation in vitro.
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Perfluoroalkyl Substance Exposure and the BDNF Pathway in the Placental Trophoblast.
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Perfluorobutane sulfonate exposure disrupted human placental cytotrophoblast cell proliferation and invasion involving in dysregulating preeclampsia related genes.
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Placental autotaxin expression is diminished in women with pre-eclampsia.
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Prothioconazole induces cell cycle arrest by up-regulation of EIF4EBP1 in extravillous trophoblast cells.
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Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus.
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Site-specific silencing of regulatory elements as a mechanism of X inactivation.
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Stimulation of GCMa transcriptional activity by cyclic AMP/protein kinase A signaling is attributed to CBP-mediated acetylation of GCMa.
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Suppressyn localization and dynamic expression patterns in primary human tissues support a physiologic role in human placentation.
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Syncytins expressed in human placental trophoblast.
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T-helper 2 and 3 type immunity to trophoblast in successful in vitro fertilization-embryo transfer.
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TMEM16F phospholipid scramblase mediates trophoblast fusion and placental development.
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The Function of TrophomiRs and Other MicroRNAs in the Human Placenta.
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The Immunology of Syncytialized Trophoblast.
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The Role of Congenital Cytomegalovirus Infection in Adverse Birth Outcomes: A Review of the Potential Mechanisms.
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The effect of cigarette smoke extract on trophoblast cell viability and migration: the role of adrenomedullin.
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The immunomodulatory roles of macrophages at the maternal-fetal interface.
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The regulation of T-cell cytokine production by ICOS-B7H2 interactions at the human fetomaternal interface.
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The requirement of SUMO2/3 for SENP2 mediated extraembryonic and embryonic development.
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The role of trophoblastic microRNAs in placental viral infection.
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Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways.
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Trophoblast class I major histocompatibility complex (MHC) products are resistant to rapid degradation imposed by the human cytomegalovirus (HCMV) gene products US2 and US11.
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Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection.
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Unc-13 homolog D mediates an antiviral effect of the chromosome 19 microRNA cluster miR-517a.
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Up-regulated cytotrophoblast DOCK4 contributes to over-invasion in placenta accreta spectrum.
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Use of a human embryonic stem cell model to discover GABRP, WFDC2, VTCN1 and ACTC1 as markers of early first trimester human trophoblast.
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Viral immunoevasive strategies and trophoblast class I major histocompatibility complex antigens.
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Vulnerability of primitive human placental trophoblast to Zika virus.
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Why certain antibodies cross-react with HLA-A and HLA-G: epitope mapping of two common MHC class I reagents.
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siRNA inhibition of aspartyl-asparaginyl β-hydroxylase expression impairs cell motility, Notch signaling, and fetal growth.
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Keywords of People