Tumor Markers, Biological

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  Subject Areas on Research

  • 5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer. 
  • A Bayesian approach to joint feature selection and classifier design. 
  • A G-CSF-secreting adrenal carcinoma with rhabdoid-like differentiation causing leukocytosis. 
  • A Phase I/biomarker study of bevacizumab in combination with CNTO 95 in patients with advanced solid tumors. 
  • A copula approach for detecting prognostic genes associated with survival outcome in microarray studies. 
  • A distinct DNA methylation signature defines pediatric pre-B cell acute lymphoblastic leukemia. 
  • A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer. 
  • A novel XPF -357A>C polymorphism predicts risk and recurrence of bladder cancer. 
  • A pathological fracture and a solitary mass in the right clavicle: an unusual first presentation of HCC and the role of immunohistochemistry. 
  • A pathway-based approach to identify molecular biomarkers in cancer. 
  • A phase I surrogate endpoint study of SU6668 in patients with solid tumors. 
  • A recurrent cerebellar lesion in a young boy. 
  • A risk-stratified approach to prostate-specific antigen screening. 
  • A single tube, four-color flow cytometry assay for evaluation of ZAP-70 and CD38 expression in chronic lymphocytic leukemia. 
  • A small cell variant of ALK-positive, CD8-positive anaplastic large cell lymphoma with primary subcutaneous presentation mimicking subcutaneous panniculitis-like T-cell lymphoma. 
  • Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors. 
  • Aberrant expression of tumor suppressor proteins in the Ewing family of tumors. 
  • Ability of C-reactive protein to complement multiple prognostic classifiers in men with metastatic castration resistant prostate cancer receiving docetaxel-based chemotherapy. 
  • Accurate identification of proliferative index in melanocytic neoplasms with Melan-A/Ki-67 double stain. 
  • Acquired vulvar lymphangioma circumscriptum: a comparison of 12 cases with Crohn's associated lesions or radiation therapy induced tumors. 
  • Acquisition of CD30 and CD15 accompanied with simultaneous loss of all pan-T-cell antigens in a case of histological transformation of mycosis fungoides with involvement of regional lymph node: an immunophenotypic alteration resembling classical Hodgkin lymphoma. 
  • Activation of the PKB/Akt pathway in histological benign prostatic tissue adjacent to the primary malignant lesions. 
  • Activity of ornithine decarboxylase (ODC) and polyamine levels as biochemical markers of malignancy in human brain tumors. 
  • Akt expression may predict favorable prognosis in cholangiocarcinoma. 
  • Alveolar soft-part sarcoma: a review and update. 
  • An immunohistochemical comparison of cytokeratin 7, cytokeratin 15, cytokeratin 19, CAM 5.2, carcinoembryonic antigen, and nestin in differentiating porocarcinoma from squamous cell carcinoma. 
  • Analysis of micrometastatic disease in sentinel lymph nodes from resectable colon cancer: results of Cancer and Leukemia Group B Trial 80001. 
  • Analysis of primary CD30+ cutaneous lymphoproliferative disease and survival from the Surveillance, Epidemiology, and End Results database. 
  • Anaplastic lymphoma kinase (ALK1) immunohistochemistry in diagnostic dermatopathology; an update. 
  • Androgen receptor mutations in androgen-independent prostate cancer: Cancer and Leukemia Group B Study 9663. 
  • Angiogenesis and molecular biologic substaging in patients with stage I non-small cell lung cancer. 
  • Application of Bayesian modeling of autologous antibody responses against ovarian tumor-associated antigens to cancer detection. 
  • Assessment of pancreatic duct strictures. 
  • Association between preoperative erectile dysfunction and prostate cancer features--an analysis from the Duke Prostate Center Database. 
  • Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab. 
  • Basal cell-signet-ring squamous cell carcinoma of the eyelid. 
  • Best screening tests for prostate cancer. 
  • Bilateral pulmonary nodules in a 37-year-old woman with malignant melanoma. Pulmonary Langerhans cell histiocytosis (eosinophilic granuloma). 
  • Biomarkers for early detection and screening in pancreatic cancer. Highlights from the 45th ASCO annual meeting. Orlando, FL, USA. May 29-June 2, 2009. 
  • Biomarkers in castration-resistant prostate cancer. 
  • Biomarkers in the ovary. 
  • Biostatistical modeling using traditional variables and genetic biomarkers for predicting the risk of prostate carcinoma recurrence after radical prostatectomy. 
  • Borderline resectable pancreatic cancer: definitions, management, and role of preoperative therapy. 
  • Breast cancer risks in individuals testing negative for a known family mutation in BRCA1 or BRCA2. 
  • Breast cancer screening-individualized risk assessment and application of new research technology: non-protein bound estradiol and chromosome analysis. 
  • CA 19-9 is an index of response to neoadjunctive chemoradiation therapy in pancreatic cancer. 
  • CD10 expression in trichoepithelioma and basal cell carcinoma. 
  • CD34 and α smooth muscle actin distinguish verrucous hyperplasia from verrucous carcinoma. 
  • CD34 immunohistochemical assessment of angiogenesis as a prognostic marker for prostate cancer recurrence after radical prostatectomy. 
  • CD4/CD8 double negative pagetoid reticulosis: a case report and literature review. 
  • COX-2, MMP-9, and Noguchi classification provide additional prognostic information about adenocarcinoma of the lung. A study of 117 patients from Brazil. 
  • Can proliferation biomarkers reliably predict recurrence in World Health Organization 2003 defined endometrial stromal sarcoma, low grade? 
  • Cancer control after low-dose-rate prostate brachytherapy performed by a multidisciplinary team with no previous prostate brachytherapy experience. 
  • Capromab Pendetide imaging of prostate cancer. 
  • Cell adhesion protein expression in melanocytic matricoma. 
  • Cellular and molecular studies in brain and nervous system oncology. 
  • Characterization of 67 kD laminin receptor, a protein whose gene is overexpressed on treatment of cells with anti-benzo[a]pyrene-7,8-diol-9,10-epoxide. 
  • Choroidal metastasis of follicular thyroid adenocarcinoma diagnosed by 25-gauge transretinal biopsy. 
  • Circulating D-dimer levels are better predictors of overall survival and disease progression than carcinoembryonic antigen levels in patients with metastatic colorectal carcinoma. 
  • Clear cell change in colonic tubular adenoma and corresponding colonic clear cell adenocarcinoma is associated with an altered mucin core protein profile. 
  • Clear cell hidradenoma: a mimic of metastatic clear cell tumors. 
  • Clinical endpoints for drug development in prostate cancer. 
  • Clinical use of serum CA-125 levels in patients undergoing radical cystectomy for transitional cell carcinoma of the bladder. 
  • Clinical utility of serum amyloid A and macrophage migration inhibitory factor as serum biomarkers for the detection of nonsmall cell lung carcinoma. 
  • Clinical validation of a customized multiple signature microarray for breast cancer. 
  • Clinical, histopathologic, and molecular markers of prognosis: toward a new disease risk stratification system for medulloblastoma. 
  • Clinicopathologic findings in high-grade B-cell lymphomas with typical Burkitt morphologic features but lacking the MYC translocation. 
  • Coincident Merkel cell carcinoma and B-cell lymphoma: a report of two cases evaluated by cytology. 
  • Combination of multiple serum markers using an artificial neural network to improve specificity in discriminating malignant from benign pelvic masses. 
  • Combined genome-wide scan for prostate cancer susceptibility genes. 
  • Combined modality therapy for rectal cancer: the relative value of posttreatment versus pretreatment CEA as a prognostic marker for disease recurrence. 
  • Combined p53 and retinoblastoma protein detection identifies persistent and regressive cervical high-grade squamous intraepithelial lesions. 
  • Common cancer biomarkers. 
  • Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker. 
  • Comparing radical prostatectomy and brachytherapy for localized prostate cancer. 
  • Composite lymphoma of mycosis fungoides and cutaneous small B-cell lymphoma in a 73-year-old male patient. 
  • Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies. 
  • Consensus report of a joint NCI thoracic malignancies steering committee: FDA workshop on strategies for integrating biomarkers into clinical development of new therapies for lung cancer leading to the inception of "master protocols" in lung cancer. 
  • Contemporary role of prostate cancer antigen 3 in the management of prostate cancer. 
  • Correspondence re: Geradts J, Wilentz RE, Roberts H. Immunohistochemical detection of the alternate ink4a-encoded tumor suppressor protein p14(arf) in archival human cancers and cell lines using commercial antibodies: correlation with p16(ink4a) expression. Mod pathol 2001;14:1162-68. 
  • Costs, effectiveness, and workload impact of management strategies for women with an adnexal mass. 
  • Cyclin D1 overexpression and response to bortezomib treatment in a breast cancer model. 
  • Cyclin E overexpression relates to ovarian cancer histology but not to risk factors. 
  • Cytologic findings of gastric schwannoma: a case report. 
  • Cytotoxic chemotherapy in the contemporary management of metastatic castration-resistant prostate cancer (mCRPC). 
  • DNA methylation and miRNA expression profiling in childhood B-cell acute lymphoblastic leukemia. 
  • Definition of a functional single nucleotide polymorphism in the cell migration inhibitory gene MIIP that affects the risk of breast cancer. 
  • Delayed radical prostatectomy for intermediate-risk prostate cancer is associated with biochemical recurrence: possible implications for active surveillance from the SEARCH database. 
  • Delta-like 1 homolog (dlk1): a marker for rhabdomyosarcomas implicated in skeletal muscle regeneration. 
  • Detection of APC mutations in fecal DNA from patients with colorectal tumors. 
  • Detection of stool DNA mutations before and after treatment of colorectal neoplasia. 
  • Diagnostic and clinical considerations in concomitant bone marrow involvement by plasma cell myeloma and chronic lymphocytic leukemia/monoclonal B-cell lymphocytosis: a series of 15 cases and review of literature. 
  • Diagnostic strategies for unknown primary cancer. 
  • Differential diagnosis in immunohistochemistry with Bayes theorem. 
  • Differential expression of N-cadherin distinguishes a subset of metastasizing desmoplastic melanomas. 
  • Discovery and verification of protein differences between Er positive/Her2/neu negative breast tumor tissue and matched adjacent normal breast tissue. 
  • Dissecting the dynamics of serum prostate-specific antigen. 
  • Do younger men have better biochemical outcomes after radical prostatectomy? 
  • Does prior benign prostate biopsy predict outcome for patients treated with radical perineal prostatectomy? 
  • Dosimetric quantifiers for low-dose-rate prostate brachytherapy: is V(100) superior to D(90)? 
  • Dynamic behavioural interpretation of cervical intraepithelial neoplasia with molecular biomarkers. 
  • ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2). 
  • Economic analysis of gene expression profile data to guide adjuvant treatment in women with early-stage breast cancer. 
  • Effect of race on biochemical disease-free outcome in patients with prostate cancer treated with definitive radiation therapy in an equal-access health care system: radiation oncology report of the Department of Defense Center for Prostate Disease Research. 
  • Effects of exercise training on fasting insulin, insulin resistance, insulin-like growth factors, and insulin-like growth factor binding proteins in postmenopausal breast cancer survivors: a randomized controlled trial. 
  • Elevated levels of apoptosis regulator proteins p53 and bcl-2 are independent prognostic biomarkers in surgically treated clinically localized prostate cancer. 
  • Elevated serum CA-125 levels: hepatitis or ascites? 
  • Endometriosis, in vitro fertilisation and the risk of gynaecological malignancies, including ovarian and breast cancer. 
  • Epidermal growth factor receptor and insulinlike growth factor 1 receptor expression predict poor survival in pancreatic ductal adenocarcinoma. 
  • Epigenetic markers in rectal cancer. 
  • Epithelial-mesenchymal transition in prostate cancer: providing new targets for therapy. 
  • Epithelioid and epithelial neoplasms of bone. 
  • Equivalent uniform dose, D(90), and V(100) correlation with biochemical control after low-dose-rate prostate brachytherapy for clinically low-risk prostate cancer. 
  • Estrogen receptor-beta expression in extraabdominal fibromatoses: an analysis of 40 cases. 
  • Estrogen-independent proliferation is present in estrogen-receptor HER2-positive primary breast cancer after neoadjuvant letrozole. 
  • Evaluation of biomarker panels for early stage ovarian cancer detection and monitoring for disease recurrence. 
  • Evaluation of expression based markers for the detection of breast cancer cells. 
  • Expression of MAGE and GAGE in high-grade brain tumors: a potential target for specific immunotherapy and diagnostic markers. 
  • Expression of MAP4K4 is associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma. 
  • Expression of cadherin/catenin cell--cell adhesion molecules in a onychomatricoma. 
  • Expression of nucleotide excision repair proteins in lymphocytes as a marker of susceptibility to squamous cell carcinomas of the head and neck. 
  • Expression of p27 in residual rectal cancer after preoperative chemoradiation predicts long-term outcome. 
  • Fatty acid synthase expression defines distinct molecular signatures in prostate cancer. 
  • Fibroblast growth factor-2 (FGF2) and syndecan-1 (SDC1) are potential biomarkers for putative circulating CD15+/CD30+ cells in poor outcome Hodgkin lymphoma patients. 
  • Fibrosarcoma-like lipomatous neoplasm: a reappraisal of so-called spindle cell liposarcoma defining a unique lipomatous tumor unrelated to other liposarcomas. 
  • Finding diagnostic biomarkers in proteomic spectra. 
  • Florid lobular carcinoma in situ: molecular profiling and comparison to classic lobular carcinoma in situ and pleomorphic lobular carcinoma in situ. 
  • Flow cytometric identification of intracellular antigens: detection of minimal residual leukemia. 
  • Folate receptor-α expression in resectable hepatic colorectal cancer metastases: patterns and significance. 
  • Functional promoter variant rs2868371 of HSPB1 is associated with risk of radiation pneumonitis after chemoradiation for non-small cell lung cancer. 
  • Fundamentals of quantitative dynamic contrast-enhanced MR imaging. 
  • Future of early detection of lung cancer: the role of mouse models. 
  • Future trends in lung cancer diagnosis. 
  • Gene expression profiles accurately predict outcome following liver resection in patients with metastatic colorectal cancer. 
  • Genetic variants in predicting aggressive prostate cancer: "ready for prime time?". 
  • Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population. 
  • Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tract. 
  • Genomic alterations and phenotype of large compared to small high-grade ductal carcinoma in situ. 
  • Genomic sweeping for hypermethylated genes. 
  • Giant cell tumor of rib masquerading as thymoma: a diagnostic pitfall in needle core biopsy of the mediastinum. 
  • Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays. 
  • Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer. 
  • Glucagon-like peptide-1 receptor agonists increase pancreatic mass by induction of protein synthesis. 
  • Growth factor receptors expression in anaplastic thyroid carcinoma: potential markers for therapeutic stratification. 
  • Guanylyl cyclase C: a molecular marker for staging and postoperative surveillance of patients with colorectal cancer. 
  • Guidelines for pathologic diagnosis of malignant mesothelioma: a consensus statement from the International Mesothelioma Interest Group. 
  • Haptoglobin and posttranslational glycan-modified derivatives as serum biomarkers for the diagnosis of nonsmall cell lung cancer. 
  • Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481). 
  • High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype. 
  • High levels of nuclear MYC protein predict the presence of MYC rearrangement in diffuse large B-cell lymphoma. 
  • High serum folate is associated with reduced biochemical recurrence after radical prostatectomy: results from the SEARCH Database. 
  • Histiocytoid carcinoma of the male breast. 
  • Histone H4 acetylation by immunohistochemistry and prognosis in relapsed acute lymphocytic leukaemia (ALL). 
  • Hydroxychloroquine-induced hyperpigmentation: the staining pattern. 
  • Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer. 
  • Identification of molecular markers for the early detection of human squamous cell carcinoma of the uterine cervix. 
  • Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil. 
  • Image-based determination of 'physiomarkers' for personalized cancer therapy. 
  • Immunobiology of malignant astrocytomas. 
  • Immunocytochemical analysis of estrogen receptors as a predictor of prognosis in breast cancer patients: comparison with quantitative biochemical methods. 
  • Immunohistochemical and genetic analysis of non-small cell and small cell gallbladder carcinoma and their precursor lesions. 
  • Immunohistochemical expression of p16 and Ki-67 correlates with degree of anal intraepithelial neoplasia. 
  • Immunohistochemical markers in fibrohistiocytic lesions: factor XIIIa, CD34, S-100 and p75. 
  • Immunohistochemistry in the diagnosis of cutaneous neoplasms. 
  • Immunotargeted nanoshells for integrated cancer imaging and therapy. 
  • Impact of NADiA ProsVue PSA slope on secondary treatment decisions after radical prostatectomy. 
  • Improved risk stratification for biochemical recurrence after radical prostatectomy using a novel risk group system based on prostate specific antigen density and biopsy Gleason score. 
  • Improvement for identification of heterophile antibody interference and AFP hook effect in immunoassays with multiplex suspension bead array system. 
  • Improving evidence developed from population-level experience with targeted agents. 
  • Improving the clinical risk score: an analysis of molecular biomarkers in the era of modern chemotherapy for resectable hepatic colorectal cancer metastases. 
  • In vivo fluorescence spectroscopy: potential for non-invasive, automated diagnosis of cervical intraepithelial neoplasia and use as a surrogate endpoint biomarker. 
  • Increased content of chondroitin sulfate proteoglycan in human colorectal carcinoma metastases compared with the primary tumor as determined by an anti-chondroitin-sulfate monoclonal antibody. 
  • Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: implication for cancer immunotherapy. 
  • Insulin-like growth factor binding protein 2: an androgen-dependent predictor of prostate cancer survival. 
  • Integrated epigenomics identifies BMP4 as a modulator of cisplatin sensitivity in gastric cancer. 
  • Integration of biomarkers and imaging. 
  • Integration of peripheral blood biomarkers with computed tomography to differentiate benign from malignant pulmonary opacities. 
  • Intraductal papillary neoplasm of the bile duct: a biliary equivalent to intraductal papillary mucinous neoplasm of the pancreas? 
  • Investigation momentum: the relentless pursuit to resolve uncertainty. 
  • Investigation of phosphoprotein signatures of archived prostate cancer tissue specimens via proteomic analysis. 
  • Invited commentary. 
  • Ki-67 expression is a prognostic marker of prostate cancer recurrence after radical prostatectomy. 
  • Lack of expression of androgen receptor may play a critical role in transformation from in situ to invasive basal subtype of high-grade ductal carcinoma of the breast. 
  • Limitations of tissue microarrays in the evaluation of focal alterations of bcl-2 and p53 in whole mount derived prostate tissues. 
  • Loss of carbamoyl phosphate synthetase I in small-intestinal adenocarcinoma. 
  • Low-risk and very-low-risk prostate cancer: is there a role for focal therapy in the era of active surveillance? Yes, the two approaches complement each other. 
  • Lymph node infarction: role of underlying malignancy, tumour proliferation fraction and vascular compromise--a study of 35 cases and a comprehensive review of the literature. 
  • Making an imperfect marker better. 
  • Malignant mesothelioma with heterologous elements: clinicopathological correlation of 27 cases and literature review. 
  • March 2000: A 16 year old female with a cerebellar mass. 
  • Medical technologies for the diagnosis of prostate cancer. 
  • Medullary thyroid carcinoma without marked elevation of calcitonin: a diagnostic and surveillance dilemma. 
  • Meningioma of the fourth ventricle. 
  • Merkel cell carcinoma: identification of prognostic factors unique to tumors located in the head and neck based on analysis of SEER data. 
  • Metastatic Merkel cell carcinoma (MCC) of pancreas and breast: a unique case. 
  • Method for improved accuracy in endogenous urea recovery marker calibrations for microdialysis in tumors. 
  • Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation. 
  • Mitochondrial mutations are a late event in the progression of head and neck squamous cell cancer. 
  • Mixed tumor of the choroid. 
  • Molecular analysis-based treatment strategies for the management of non-small cell lung cancer. 
  • Molecular biologic staging of esophageal cancer. 
  • Molecular biologic staging of lung cancer. 
  • Molecular biologic substaging of stage I NSCLC through immunohistochemistry performed on formalin-fixed, paraffin-embedded tissue. 
  • Molecular biology of esophageal cancer. 
  • Molecular investigation of lymph nodes in colon cancer patients using one-step nucleic acid amplification (OSNA): a new road to better staging? 
  • Molecular markers for incidence, prognosis, and response to therapy. 
  • Molecular markers of therapeutic resistance in breast cancer. 
  • Molecular prediction of recurrence of breast cancer. 
  • Molecular signatures of thyroid follicular neoplasia. 
  • Molecular staging and the selection of therapy for non-small cell lung cancer. 
  • Monoclonal antibody against human colonic sulfomucin: immunochemical detection of its binding sites in colonic mucosa, colorectal primary carcinoma, and metastases. 
  • Morphologic features of 115 lymphomas of the orbit and ocular adnexa categorized according to the World Health Organization classification: are marginal zone lymphomas in the orbit mucosa-associated lymphoid tissue-type lymphomas? 
  • Multicenter clinical validation of PITX2 methylation as a prostate specific antigen recurrence predictor in patients with post-radical prostatectomy prostate cancer. 
  • Multiclass cancer diagnosis using tumor gene expression signatures. 
  • Myoid differentiation and prognosis in adult pleomorphic sarcomas of the extremity: an analysis of 92 cases. 
  • NADiA ProsVue prostate-specific antigen slope, CAPRA-S, and prostate cancer--specific survival after radical prostatectomy. 
  • Near-infrared optical imaging of integrin alphavbeta3 in human tumor xenografts. 
  • Novel breast cancer biomarkers identified by integrative proteomic and gene expression mapping. 
  • Novel prognostic markers for patients with triple-negative breast cancer. 
  • Nucleotide excision repair as a marker for susceptibility to tobacco-related cancers: a review of molecular epidemiological studies. 
  • Obesity and risk of biochemical progression following radical prostatectomy at a tertiary care referral center. 
  • Opportunities for near-infrared thermal ablation of colorectal metastases by guanylyl cyclase C-targeted gold nanoshells. 
  • Ovarian adenocarcinomas in the laying hen and women share similar alterations in p53, ras, and HER-2/neu. 
  • Overall survival benefit with lapatinib in combination with trastuzumab for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: final results from the EGF104900 Study. 
  • Overexpression of folate binding protein is associated with shortened progression-free survival in uterine adenocarcinomas. 
  • Overexpression of synuclein-gamma in pancreatic adenocarcinoma. 
  • PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: associations with localized stage progression. 
  • Paget disease of the vulva: a histologic study of 56 cases correlating pathologic features and disease course. 
  • Pancreatoblastoma in a teenage patient. 
  • Panel of serum biomarkers for the diagnosis of lung cancer. 
  • Pathologic stage T2a and T2b prostate cancer in the recent prostate-specific antigen era: implications for unilateral ablative therapy. 
  • Pathological bone fractures in a 20-year old athletic male with multifocal solitary plasmacytoma of bone. 
  • Patterns of GRP78 and MTJ1 expression in primary cutaneous malignant melanoma. 
  • Patterns of gene expression in different histotypes of epithelial ovarian cancer correlate with those in normal fallopian tube, endometrium, and colon. 
  • Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma. 
  • Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas. 
  • Phase II study of predictive biomarker profiles for response targeting human epidermal growth factor receptor 2 (HER-2) in advanced inflammatory breast cancer with lapatinib monotherapy. 
  • Phase II trial of dasatinib in patients with metastatic breast cancer using real-time pharmacodynamic tissue biomarkers of Src inhibition to escalate dosing. 
  • Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127. 
  • Polymorphisms in the prostate-specific antigen gene promoter do not predict serum prostate-specific antigen levels in African-American men. 
  • Polymorphisms of the neuronal and inducible nitric oxide synthase genes and the risk of cutaneous melanoma: a case-control study. 
  • Pooling of case specimens to create standard serum sets for screening cancer biomarkers. 
  • Potential predictive biomarkers for individualizing treatment for men with castration-resistant prostate cancer. 
  • Predicting unilateral prostate cancer based on biopsy features: implications for focal ablative therapy--results from the SEARCH database. 
  • Prediction of disease-free survival in hepatocellular carcinoma by gene expression profiling. 
  • Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays. 
  • Predictive value of the EphA2 receptor tyrosine kinase in lung cancer recurrence and survival. 
  • Preoperative p27 status is an independent predictor of prostate specific antigen failure following radical prostatectomy. 
  • Preoperative sensitivity and specificity for early-stage ovarian cancer when combining cancer antigen CA-125II, CA 15-3, CA 72-4, and macrophage colony-stimulating factor using mixtures of multivariate normal distributions. 
  • Pretreatment prostate-specific antigen velocity is associated with freedom from biochemical recurrence of prostate cancer after low-dose-rate prostate brachytherapy alone. 
  • Prevention and early detection of cancer. 
  • Primary cerebral ALK-1-positive anaplastic large cell lymphoma in a child. Case report and literature review. 
  • Primary intraocular T-cell-rich large B-cell lymphoma. 
  • Primary lung cancer vs metastatic breast cancer: a probabilistic approach. 
  • Primary mediastinal (thymic) large B-cell lymphoma: a short review with brief discussion of mediastinal gray zone lymphoma. 
  • Primary mucinous carcinoma of the eyelid: a clinicopathologic and immunohistochemical study of 4 cases and an update on recurrence rates. 
  • Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999. 
  • Prognostic factors in low-stage nonseminomatous testicular cancer. 
  • Prognostic modeling in early stage lung cancer: an evolving process from histopathology to genomics. 
  • Prognostic significance of overexpression and phosphorylation of epidermal growth factor receptor (EGFR) and the presence of truncated EGFRvIII in locoregionally advanced breast cancer. 
  • Prostate Cancer and Prostatic Diseases. Editor's comments. 
  • Prostate biopsies from black men express higher levels of aggressive disease biomarkers than prostate biopsies from white men. 
  • Prostate brachytherapy: a descriptive analysis from CaPSURE. 
  • Prostate-specific antigen as a marker of disease activity in prostate cancer. 
  • Prostate-specific antigen as a marker of disease activity in prostate cancer. 
  • Protein C inhibitor (plasminogen activator inhibitor-3) expression in the CWR22 prostate cancer xenograft. 
  • Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer. 
  • Protocol for the examination of specimens from patients with primary non-small cell carcinoma, small cell carcinoma, or carcinoid tumor of the lung. 
  • Quantitative expression profile of PSGR in prostate cancer. 
  • RE: net risk reclassification P Values: valid or misleading? 
  • Race and the linkage between serum prostate-specific antigen and prostate cancer: a study of American veterans. 
  • Radical prostatectomy lowers plasma vascular endothelial growth factor levels in patients with prostate cancer. 
  • Radiogenomic analysis of breast cancer: luminal B molecular subtype is associated with enhancement dynamics at MR imaging. 
  • Radiotherapy for locally recurrent prostate cancer. 
  • Rationale for percutaneous biopsy and histologic characterisation of renal tumours. 
  • Re: Prostate-specific antigen: a misused and maligned prostate cancer biomarker. 
  • Recent developments in predicting thyroid malignancy. 
  • Rectal cancer: the influence of tumor proliferation on response to preoperative irradiation. 
  • Refocusing the war on cancer: the critical role of personalized treatment. 
  • Relative quantification based on logistic models for individual polymerase chain reactions. 
  • Reply: To PMID 25432832. 
  • Report from Durham. 
  • Report from Durham. 
  • Reproducibility and variability of the rectal mucosal proliferation index using proliferating cell nuclear antigen immunohistochemistry. 
  • Resection of adrenocortical carcinoma liver metastasis: is it justified? 
  • Rising PSA after local therapy failure: immediate vs deferred treatment. 
  • Sam-pointed domain containing Ets transcription factor in luminal breast cancer pathogenesis. 
  • Sarcomatoid mesothelioma: a clinical-pathologic correlation of 326 cases. 
  • Secretory meningiomas of the orbit. 
  • Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis. 
  • Serum CA19-9 response as a surrogate for clinical outcome in patients receiving fixed-dose rate gemcitabine for advanced pancreatic cancer. 
  • Serum CYFRA 21-1 in advanced stage non-small cell lung cancer: an early measure of response. 
  • Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer. 
  • Serum insulin levels and the prevalence of adenomatous and hyperplastic polyps in the proximal colon. 
  • Serum protein expression predicts recurrence in patients with early-stage lung cancer after resection. 
  • Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastoma. 
  • Statistical algorithm for assuring similar efficiency in standards and samples for absolute quantification by real-time reverse transcription polymerase chain reaction. 
  • Statistical analysis of the concordance of immunohistochemical stains with the final diagnosis in spitzoid neoplasms. 
  • Statistical considerations and modeling of clinical utility of tumor markers. 
  • Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies. 
  • Surrogate markers in antiangiogenesis clinical trials. 
  • Survival analysis of presumptive prognostic markers among oligodendrogliomas. 
  • Syndecan-1 expression in prostate cancer and its value as biomarker for disease progression. 
  • Template for reporting results of biomarker testing of specimens from patients with carcinoma of the colon and rectum. 
  • Testicular cancer. Clinical practice guidelines. 
  • The Association of Intratumoral Germinal Centers with early-stage non-small cell lung cancer. 
  • The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer. 
  • The application of monoclonal antibodies in the cytologic evaluation of tumors. 
  • The contemporary value of pretreatment prostatic acid phosphatase to predict pathological stage and recurrence in radical prostatectomy cases. 
  • The correlation of serial prostate specific antigen measurements with clinical outcome after external beam radiation therapy of patients for prostate carcinoma. 
  • The current clinical value of the DCIS Score. 
  • The effect of altered Toll-like receptor 4 signaling on cancer cachexia. 
  • The evolution of the histology in pleomorphic xanthoastrocytomas in children: a study of 15 cases. 
  • The impact of PSA on prostate cancer management. Can we abandon routine staging pelvic lymphadenectomy? 
  • The influence of statin medications on prostate-specific antigen levels. 
  • The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2. 
  • The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features. 
  • The prognostic significance of multiple morphologic features and biologic markers in ductal carcinoma in situ of the breast: a study of a large cohort of patients treated with surgery alone. 
  • The requirements for CTL-mediated rejection of cancer in humans: NKG2D and its role in the immune responsiveness of melanoma. 
  • The role of surrogate markers in the management of men with metastatic castration-resistant prostate cancer. 
  • The significance of syndecan-1 expression in patients treated with radical prostatectomy. Commentary. 
  • The uncertain relationship between obesity and prostate cancer: an Italian biopsy cohort analysis. 
  • Therapeutic tools in pancreatic cancer. 
  • Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer. 
  • Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection. 
  • Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion. 
  • Transforming growth factor alpha and epidermal growth factor receptor in reactive and malignant mesothelial proliferations. 
  • Transglutaminase activity in human brain tumors. 
  • Translating biomarkers into clinical practice: prognostic implications of cyclophilin A and macrophage migratory inhibitory factor identified from protein expression profiles in non-small cell lung cancer. 
  • Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: multicenter phase II trial with clinical outcomes, analysis of serum tumor markers as predictive factors, and cardiac surveillance algorithm. 
  • Triple-negative breast cancer: clinicopathological characteristics and relationship with basal-like breast cancer. 
  • Trophinin is a potent prognostic marker of ovarian cancer involved in platinum sensitivity. 
  • Tumor antigens in astrocytic gliomas. 
  • Tumor immunotherapy targeting fibroblast activation protein, a product expressed in tumor-associated fibroblasts. 
  • Tumor volume in prostate cancer and serum prostate-specific antigen. Analysis from a kinetic viewpoint. 
  • Two serologic markers to monitor the engraftment, growth, and treatment response of human leukemias in severe combined immunodeficient mice. 
  • Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer. 
  • Uncorrectable ptosis: primary cutaneous signet-ring cell carcinoma. 
  • Up-regulation of proline-rich tyrosine kinase 2 in non-small cell lung cancer. 
  • Upregulation of the tissue inhibitor of metalloproteinase-1 protein is associated with progression of human non-small-cell lung cancer. 
  • Urea as a recovery marker for quantitative assessment of tumor interstitial solutes with microdialysis. 
  • Urinary fibronectin as a predictor of a residual tumour load after transurethral resection of bladder transitional cell carcinoma. 
  • Usefulness of prostate-specific antigen (PSA) rise as a marker of prostate cancer in men treated with dutasteride: lessons from the REDUCE study. 
  • Using surrogate biomarkers to predict clinical benefit in men with castration-resistant prostate cancer: an update and review of the literature. 
  • Utility of immunohistochemistry in predicting microsatellite instability in endometrial carcinoma. 
  • Utilizing quantitative polymerase chain reaction to evaluate prostate stem cell antigen as a tumor marker in pancreatic cancer. 
  • Value of CD23 determination by flow cytometry in differentiating mantle cell lymphoma from chronic lymphocytic leukemia/small lymphocytic lymphoma. 
  • Vascular endothelial growth factor and basic fibroblast growth factor urine levels as predictors of outcome in hormone-refractory prostate cancer patients: a cancer and leukemia group B study. 
  • Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors. 
  • Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression. 
  • Zinc alpha-2-glycoprotein is expressed by malignant prostatic epithelium and may serve as a potential serum marker for prostate cancer. 
  • [Significance of monoclonal antibodies in diagnosis and therapy of tumors of the central nervous system]. 
  • alphaB-crystallin is a novel predictor of resistance to neoadjuvant chemotherapy in breast cancer. 
  • miRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy. 
  • p53 nuclear protein expression is an independent prognostic marker in clinically localized prostate cancer patients undergoing radical prostatectomy. 
  • p53, c-erbB2, and PCNA status in benign, proliferative and malignant ovarian surface epithelial neoplasms: a study of 75 cases. 
  • p63 expression profile in normal and malignant prostate epithelial cells. 
• 

  Keywords of People

  • Abbruzzese, James, D. C. I. Professor of Medical Oncology, Medicine, Medical Oncology
  • Badea, Cristian Tudorel, Professor in Radiology, Biomedical Engineering
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Bitting, Rhonda L, Instructor in the Department of Medicine, Medicine, Medical Oncology
  • Charles, Hal Cecil, Associate Professor of Radiology, Radiology
  • Chitneni, Satish K., Associate Professor in Radiology, Radiology
  • Clyde, Merlise, Professor of Statistical Science, Statistical Science
  • Esclamado, Ramon Mitra, Richard Hall Chaney, Sr. Distinguished Professor of Otolaryngology, Surgery, Head and Neck Surgery and Communication Sciences
  • Gottlin, Elizabeth B., Assistant Professor in Radiology, Radiology
  • Halabi, Susan, Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Hirschey, Matthew, Associate Professor, Pharmacology & Cancer Biology
  • Jowell, Paul Simon, Professor of Medicine, Medicine, Gastroenterology
  • Koontz, Bridget Fey, Associate Professor of Radiation Oncology, Radiation Oncology
  • Lee, Walter T, Associate Professor of Head and Neck Surgery and Communication Sciences, Radiation Oncology
  • Linardic, Corinne Mary, Associate Professor of Pediatrics, Pharmacology & Cancer Biology
  • Lopez, Giselle Yvette, Assistant Professor in Pathology, Pathology
  • McCall, Shannon Jones, Associate Professor of Pathology, Pathology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Moorman, Patricia Gripka, Professor in Family Medicine and Community Health, Duke Cancer Institute
  • Mruthyunjaya, Prithvi, Adjunct Associate Professor in the Department of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery
  • Palmer, Gregory M., Associate Professor of Radiation Oncology, Radiation Oncology
  • Pang, Herbert, Adjunct Assistant Professor in the Department of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Patz Jr., Edward F., James and Alice Chen Distinguished Professor of Radiology, Pathology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Immunology
  • Stoecker, Maggie Marie, Assistant Professor of Pathology, Pathology
  • Turkington, Timothy Garvey, Associate Professor in Radiology, Radiology
  • Uronis, Hope Elizabeth, Associate Professor of Medicine, Medicine, Medical Oncology
  • Woodward, Julie Ann, Professor of Ophthalmology, Dermatology
  • Yan, Hai, Henry S. Friedman Distinguished Professor of Neuro-Oncology in the School of Medicine, Pathology
  • Zafar, Syed Yousuf, Associate Professor of Medicine, Medicine, Medical Oncology