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Subject Areas on Research
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3-nitrotyrosine attenuates respiratory syncytial virus infection in human bronchial epithelial cell line.
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A New Protocol for Anticoagulation With Tirofiban During Flow Diversion.
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A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation.
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A cell cycle checkpoint monitors cell morphogenesis in budding yeast.
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A high resolution structure of an inhibitor complex of the extracellular nuclease of Staphylococcus aureus. I. Experimental procedures and chain tracing.
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A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration.
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A hot oxidant, 3-NO2Y122 radical, unmasks conformational gating in ribonucleotide reductase.
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A human erythropoietin receptor gene mutant causing familial erythrocytosis is associated with deregulation of the rates of Jak2 and Stat5 inactivation.
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A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction.
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A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury.
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A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.
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A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth.
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A positive addition to a negative tail's tale.
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A symposium: safety issues concerning the use of glycoprotein IIb-IIIa inhibitors in the management of acute coronary syndromes.
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A tale of two trials: a comparison of the post-acute coronary syndrome lipid-lowering trials A to Z and PROVE IT-TIMI 22.
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Abl kinases regulate actin comet tail elongation via an N-WASP-dependent pathway.
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Abl tyrosine kinase regulates endocytosis of the epidermal growth factor receptor.
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Abundant tyrosine residues in the antigen binding site in anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: Application to radiolabeling.
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Activated c-Abl is degraded by the ubiquitin-dependent proteasome pathway.
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Activation of EGF receptors mediates pulmonary vasoconstriction induced by residual oil fly ash.
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Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation.
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Adrenal medullary storage vesicles of the spontaneously hypertensive rat.
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Altered expression of pp60c-src induced by peripheral nerve injury.
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An active site tyrosine influences the ability of the dimethyl sulfoxide reductase family of molybdopterin enzymes to reduce S-oxides.
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An automated strategy for bedside aPTT determination and unfractionated heparin infusion adjustment in acute coronary syndromes: insights from PARAGON A.
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An inner activation gate controls TMEM16F phospholipid scrambling.
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Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells
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Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells.
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Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia.
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Antiplatelet and anticoagulation agents in acute coronary syndromes: what is the current status and what does the future hold?
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Antithrombotic therapy for non-ST-segment elevation acute coronary syndromes: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
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Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling.
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Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase.
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Autocrine growth stimulation by transforming growth factor alpha in asbestos-transformed rat mesothelial cells.
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B cell antigen receptor and CD40 differentially regulate CD22 tyrosine phosphorylation.
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BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner.
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Benefit of glycoprotein IIb/IIIa inhibition in patients with acute coronary syndromes and troponin t-positive status: the paragon-B troponin T substudy.
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Beta-catenin expression in Dupuytren's disease: potential role for cell-matrix interactions in modulating beta-catenin levels in vivo and in vitro.
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Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).
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CD19 amplification of B lymphocyte Ca2+ responses: a role for Lyn sequestration in extinguishing negative regulation.
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CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation.
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CD19 and CD22 expression reciprocally regulates tyrosine phosphorylation of Vav protein during B lymphocyte signaling.
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CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes.
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CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.
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CD28 ligation induces rapid tyrosine phosphorylation of the linker molecule LAT in the absence of Syk and ZAP-70 tyrosine phosphorylation.
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CD9 plays a role in Schwann cell migration in vitro.
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CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion.
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Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants.
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Cdc34 and the F-box protein Met30 are required for degradation of the Cdk-inhibitory kinase Swe1.
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Cellular response to phase-separated blends of tyrosine-derived polycarbonates.
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Cerebrospinal Fluid Pterins, Pterin-Dependent Neurotransmitters, and Mortality in Pediatric Cerebral Malaria.
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Characterization of avian and viral p60src proteins expressed in yeast.
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Chemical modification of alpha 2-adrenoceptors. Possible role for tyrosine in the ligand binding site.
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Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization.
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Clinical challenges of platelet glycoprotein IIb/IIIa receptor inhibitor therapy: bleeding, reversal, thrombocytopenia, and retreatment.
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Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial.
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Combined assessment of thrombolysis in myocardial infarction flow grade, myocardial perfusion grade, and ST-segment resolution to evaluate epicardial and myocardial reperfusion.
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Combining thrombolysis with the platelet glycoprotein IIb/IIIa inhibitor lamifiban: results of the Platelet Aggregation Receptor Antagonist Dose Investigation and Reperfusion Gain in Myocardial Infarction (PARADIGM) trial.
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Comparison of ST-segment resolution with combined fibrinolytic and glycoprotein IIb/IIIa inhibitor therapy versus fibrinolytic alone (data from four clinical trials).
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Compartmentalized NRG signaling and PDZ domain-containing proteins in synapse structure and function.
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Complementary roles for CD19 and Bruton's tyrosine kinase in B lymphocyte signal transduction.
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Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues.
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Conformational dynamics of amyloid beta-protein assembly probed using intrinsic fluorescence.
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Consequences of (129)Xe-(1)H cross relaxation in aqueous solutions.
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Conserved Residues Control Activation of Mammalian G Protein-Coupled Odorant Receptors.
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Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia.
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Conversion of Tyr361 beta to Leu in mammalian protein farnesyltransferase impairs product release but not substrate recognition.
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Corneal organ cultures in tyrosinemia release chemotactic factors.
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Cost and cost-effectiveness of an early invasive vs conservative strategy for the treatment of unstable angina and non-ST-segment elevation myocardial infarction.
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Crystalloids in salivary gland pleomorphic adenomas.
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Current knowledge of the platelet glycoprotein IIb/IIIa receptor antagonists for the treatment of coronary artery disease.
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DNA repair protein O6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells.
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Defusing redox bombs?
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Determinants of backbone dynamics in native BPTI: cooperative influence of the 14-38 disulfide and the Tyr35 side-chain.
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Dietary manipulation of serotonergic and dopaminergic function in C57BL/6J mice with amino acid depletion mixtures.
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Differences among the parenteral platelet glycoprotein IIb/IIIa inhibitors and implications for treatment.
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Differential effects of platelet-derived growth factor isotypes on human smooth muscle cell proliferation and migration are mediated by distinct signaling pathways.
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Differential susceptibility of yeast S and M phase CDK complexes to inhibitory tyrosine phosphorylation.
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Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase.
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Distribution, levels and phosphorylation of Raf-1 in Alzheimer's disease.
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Does the discharge ECG provide additional prognostic insight(s) in non-ST elevation ACS patients from that acquired on admission?
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Dual enzymatic formation of hybrid hydrogels with supramolecular-polymeric networks.
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ESPRIT in context: pharmacology matters!
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Early response monitoring of receptor tyrosine kinase inhibitor therapy in metastatic renal cell carcinoma using [F-18]fluorothymidine-positron emission tomography-magnetic resonance.
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Economic impact of GPIIB/IIIA blockade after high-risk angioplasty: results from the RESTORE trial. Randomized Efficacy Study of Tirofiban for Outcomes and Restenosis.
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Economics, health-related quality of life, and cost-effectiveness methods for the TACTICS (Treat Angina With Aggrastat [tirofiban]] and Determine Cost of Therapy with Invasive or Conservative Strategy)-TIMI 18 trial.
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Effect of FSH on protein biosynthesis in testes of the immature rat.
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Effect of intensive lipid-lowering therapy on mortality after acute coronary syndrome (a patient-level analysis of the Aggrastat to Zocor and Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 trials).
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Effect of statin dose on incidence of atrial fibrillation: data from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) and Aggrastat to Zocor (A to Z) trials.
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Elevated plasma phenylalanine in severe malaria and implications for pathophysiology of neurological complications.
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En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase.
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Endothelial cell junctions and the regulation of vascular permeability and leukocyte transmigration.
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Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt.
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Endotoxin mediated-iNOS induction causes insulin resistance via ONOO⁻ induced tyrosine nitration of IRS-1 in skeletal muscle.
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Enhanced protein flexibility caused by a destabilizing amino acid replacement in BPTI.
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Enoxaparin versus unfractionated heparin in patients treated with tirofiban, aspirin and an early conservative initial management strategy: results from the A phase of the A-to-Z trial.
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Enzymatically inactive p60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region.
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Equilibration of tyrosyl radicals (Y356•, Y731•, Y730•) in the radical propagation pathway of the Escherichia coli class Ia ribonucleotide reductase.
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Erythropoietin hypersensitivity in primary familial and congenital polycythemia: role of tyrosines Y285 and Y344 in erythropoietin receptor cytoplasmic domain.
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Essential roles for calcium and calmodulin in G2/M progression in Aspergillus nidulans.
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Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor.
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FIGQY phosphorylation defines discrete populations of L1 cell adhesion molecules at sites of cell-cell contact and in migrating neurons.
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Farglitazar lacks antifibrotic activity in patients with chronic hepatitis C infection.
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Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.
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Fibrogenesis assessed by serological type III collagen formation identifies patients with progressive liver fibrosis and responders to a potential antifibrotic therapy.
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Formation of DNA-protein cross-links in cultured mammalian cells upon treatment with iron ions.
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Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line.
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Functional interaction between c-Abl and the p21-activated protein kinase gamma-PAK.
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Functional properties of carboxypeptidase-digested hemoglobins.
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Functional significance of the central helix in calmodulin.
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G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases.
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G-protein-coupled receptors and their regulation: activation of the MAP kinase signaling pathway by G-protein-coupled receptors.
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GYGD pore motifs in neighbouring potassium channel subunits interact to determine ion selectivity.
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Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation.
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Glutamate 350 Plays an Essential Role in Conformational Gating of Long-Range Radical Transport in Escherichia coli Class Ia Ribonucleotide Reductase.
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Glycoprotein IIb/IIIa inhibitors in acute coronary syndromes.
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Glycoprotein IIb/IIIa receptor inhibitors: putting the EPIC, IMPACT II, RESTORE, and EPILOG trials into perspective.
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High-content profiling of cell responsiveness to graded substrates based on combinyatorially variant polymers.
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High-resolution solution structure of the beryllofluoride-activated NtrC receiver domain.
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Homeostatic mechanisms in dopamine synthesis and release: a mathematical model.
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Hydrophobic residues Phe751 and Leu753 are essential for STAT5 transcriptional activity.
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ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration.
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Identification of a residue critical for maintaining the functional conformation of BPTI.
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Immunotoxin FN18-CRM9 induces stronger T cell signaling than unconjugated monoclonal antibody FN18.
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Impact of glycoprotein IIb/IIIa inhibitors on the efficacy and safety of ticagrelor compared with clopidogrel in patients with acute coronary syndromes: Analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial.
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Impact of polymer-bound iodine on fibronectin adsorption and osteoblast cell morphology in radiopaque medical polymers: tyrosine-derived polycarbonate blends as a model system.
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Improved excitation pulse bandwidths using shaped pulses, with application to heteronuclear half filters in macromolecular NMR.
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In Reply: Safety and Efficacy Issues of Tirofiban Use in Endovascular Procedures: What Are the Actual Indications?
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In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail.
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Incorporation of tyrosine and glutamine residues into the soluble guanylate cyclase heme distal pocket alters NO and O2 binding.
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Induction of urinary excretion of 3-nitrotyrosine, a marker of oxidative stress, following administration of pyridostigmine bromide, DEET (N,N-diethyl-m-toluamide) and permethrin, alone and in combination in rats.
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Influence of Nitrosative Stress on Fatigue During Childhood Leukemia Treatment.
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Influence of oxygen tension on interleukin 1-induced peroxynitrite formation and matrix turnover in articular cartilage.
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Inhibition of iNOS attenuates skeletal muscle reperfusion injury in extracellular superoxide dismutase knockout mice.
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Inhibition of lysyl hydroxylase by catechol analogs.
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Insulin receptor substrate-1 (IRS-1) expression in rat brain.
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Interaction of photoreactive and fluorescent nucleotides with chloroplast coupling factor 1.
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Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766.
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Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor.
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Iodonitrene in Action: Direct Transformation of Amino Acids into Terminal Diazirines and 15
N2
-Diazirines and Their Application as Hyperpolarized Markers.
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Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development.
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L-DOPA is an endogenous ligand for OA1.
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LAB: a new membrane-associated adaptor molecule in B cell activation.
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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway.
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LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI.
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LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation.
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Ligation of cell surface-associated glucose-regulated protein 78 by receptor-recognized forms of alpha 2-macroglobulin: activation of p21-activated protein kinase-2-dependent signaling in murine peritoneal macrophages.
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Ligation of the alpha 2-macroglobulin signalling receptor on macrophages induces protein phosphorylation and an increase in cytosolic pH.
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Lovastatin-induced cytoskeletal reorganization in lens epithelial cells: role of Rho GTPases.
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M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1.
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M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice.
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Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders.
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Metabolites and diabetes remission after weight loss.
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Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.
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Modulation of B lymphocyte antigen receptor signal transduction by a CD19/CD22 regulatory loop.
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Morphine-reserpine interactions in the adrenal medulla.
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Mutants of Fujinami sarcoma virus which are temperature sensitive for cellular transformation and protein kinase activity.
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Mutational analysis of the tyrosine phosphatome in colorectal cancers.
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Mutual regulation of Src family kinases and the neurotrophin receptor TrkB.
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N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents.
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N-terminal tyrosine modulation of the endocytic adaptor function of the beta-arrestins.
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NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment.
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Neurite outgrowth is enhanced by anti-idiotypic monoclonal antibodies to the ganglioside GM1.
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Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease.
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Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.
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Nitration of tyrosine by hydrogen peroxide and nitrite.
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Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in african-americans.
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Nitric oxide synthase inhibitors decrease coronary sinus-free radical concentration and ameliorate myocardial stunning in an ischemia-reperfusion model.
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Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries.
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Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression.
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One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate.
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Ordered phosphorylation of p42mapk by MAP kinase kinase.
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Outcomes of patients with acute coronary syndrome and previous coronary artery bypass grafting (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy [PROVE IT-TIMI 22] and the Aggrastat to Zocor [A to Z] trials).
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Oxidative stress in human abdominal aortic aneurysms: a potential mediator of aneurysmal remodeling.
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PDGF-BB, IGF-I and mechanical load stimulate DNA synthesis in avian tendon fibroblasts in vitro.
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PPARgamma agonists prevent TGFbeta1/Smad3-signaling in human hepatic stellate cells.
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PTEN as an effector in the signaling of antimigratory G protein-coupled receptor.
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Peptide-Functionalized Fluorescent Particles for In Situ Detection of Nitric Oxide via Peroxynitrite-Mediated Nitration.
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Perinatal western-type diet and associated gestational weight gain alter postpartum maternal mood.
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Pharmacosimulation of delays and interruptions during administration of tirofiban: a systematic comparison between EU and US dosage regimens.
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Phenylalanine hydroxylase activity in mammalian cells.
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Phorbol ester inhibits granulocyte-macrophage colony-stimulating factor binding and tyrosine phosphorylation.
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Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation.
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Phosphorylation at tyrosine 262 promotes GADD34 protein turnover.
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Piceatannol in combination with low doses of cyclosporine A prolongs kidney allograft survival in a stringent rat transplantation model.
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Platelet glycoprotein IIb/IIIa receptor antagonists in non-ST segment elevation acute coronary syndromes: a review and guide to patient selection.
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Platelet inhibition strategies in percutaneous coronary intervention: competition or coopetition?
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Platelet-activating factor induces tyrosine phosphorylation in human neutrophils.
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Point-of-care measured platelet inhibition correlates with a reduced risk of an adverse cardiac event after percutaneous coronary intervention: results of the GOLD (AU-Assessing Ultegra) multicenter study.
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Poliovirus entry into human brain microvascular cells requires receptor-induced activation of SHP-2.
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Positive and negative regulation of FcepsilonRI-mediated signaling by the adaptor protein LAB/NTAL.
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Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction.
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Posttranslational modifications of tubulin in teleost photoreceptor cytoskeletons.
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Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor).
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Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase.
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Promise of combined low-molecular-weight heparin and platelet glycoprotein IIb/IIIa inhibition: results from Platelet IIb/IIIa Antagonist for the Reduction of Acute coronary syndrome events in a Global Organization Network B (PARAGON B).
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Prostaglandin F2 alpha-induced mitogenesis in MC3T3-E1 osteoblasts: role of protein kinase-C-mediated tyrosine phosphorylation.
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Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling.
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Proteasome inhibitor attenuates skeletal muscle reperfusion injury by blocking the pathway of nuclear factor-kappaB activation.
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Protective effects of ischemic preconditioning on the cold-preserved liver are tyrosine kinase dependent.
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Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives.
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Pseudomonas invasion of type I pneumocytes is dependent on the expression and phosphorylation of caveolin-2.
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Randomized COMparison of platelet inhibition with abciximab, tiRofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: the COMPARE trial. Comparison Of Measurements of Platelet aggregation with Aggrastat, Reopro, and Eptifibatide.
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Rapid diagnosis of phenylketonuria by quantitative analysis for phenylalanine and tyrosine in neonatal blood spots by tandem mass spectrometry.
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Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase.
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Rationale and clinical evidence for the use of GP IIb/IIIa inhibitors in acute coronary syndromes.
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Recent antiplatelet drug trials in the acute coronary syndromes. Clinical interpretation of PRISM, PRISM-PLUS, PARAGON A and PURSUIT.
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Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway.
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Reciprocal regulation of the platelet-derived growth factor receptor-beta and G protein-coupled receptor kinase 5 by cross-phosphorylation: effects on catalysis.
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Recombinant heregulin-Pseudomonas exotoxin fusion proteins: interactions with the heregulin receptors and antitumor activity in vivo.
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Reduced synthesis of pp60src and expression of the transformation-related phenotype in interferon-treated Rous sarcoma virus-transformed rat cells.
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Regulation of ZAP-70 intracellular localization: visualization with the green fluorescent protein.
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Regulation of the brain's vascular responses to oxygen.
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Renaturation and partial peptide sequencing of mitogen-activated protein kinase (MAP kinase) activator from rabbit skeletal muscle.
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Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.
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Role of conserved tyrosine 343 in intramolecular electron transfer in human sulfite oxidase.
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Role of the sixth transmembrane segment of domain IV of the cockroach sodium channel in the action of sodium channel blocker insecticides.
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Safety and efficacy of enoxaparin vs unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes who receive tirofiban and aspirin: a randomized controlled trial.
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Safety and efficacy of tirofiban in stent-assisted coil embolization of intracranial aneurysms.
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Selective antiviral activity of synthetic soluble L-tyrosine and L-dopa melanins against human immunodeficiency virus in vitro.
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Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy.
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Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56δ stabilizes its antiapoptotic activity.
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Serotonin shapes risky decision making in monkeys.
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Sex differences in major bleeding with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) initiative.
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Sex steroid receptor analysis in human melanoma.
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Similar but not the same: normobaric and hyperbaric pulmonary oxygen toxicity, the role of nitric oxide.
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Site-directed mutagenesis in the effector site of Escherichia coli phosphofructokinase.
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Site-specific incorporation of 3-nitrotyrosine as a probe of pKa perturbation of redox-active tyrosines in ribonucleotide reductase.
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Site-specific mutagenesis of Drosophila alcohol dehydrogenase: evidence for involvement of tyrosine-152 and lysine-156 in catalysis.
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Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.
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Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling.
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Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling.
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Stimulation of Sky tyrosine phosphorylation by bovine protein S--domains involved in the receptor-ligand interaction.
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Stimulation of different subtypes of angiotensin II receptors, AT1 and AT2 receptors, regulates STAT activation by negative crosstalk.
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Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR.
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Structural organization of chloroplast coupling factor.
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Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry.
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Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4.
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TRPV4 channels augment macrophage activation and ventilator-induced lung injury.
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TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs.
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Tenecteplase and tirofiban in ST-segment elevation acute myocardial infarction: results of a randomized trial.
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The A-to-Z Trial: Methods and rationale for a single trial investigating combined use of low-molecular-weight heparin with the glycoprotein IIb/IIIa inhibitor tirofiban and defining the efficacy of early aggressive simvastatin therapy.
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The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer.
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The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals.
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The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.
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The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia-like disease by bcr/abl.
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The complementary use of glycoprotein IIb/IIIa inhibitors and drug-eluting stents in contemporary percutaneous coronary intervention.
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The effect of phencyclidine on dopamine metabolism in the mouse brain.
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The effects of tempol on cyclophosphamide-induced oxidative stress in rat micturition reflexes.
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The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB.
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The influence of oxygen tension on the induction of nitric oxide and prostaglandin E2 by mechanical stress in articular cartilage.
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The isoforms of phospholipase C-gamma are differentially used by distinct human NK activating receptors.
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The nitric oxide synthase inhibitor N(G)-nitro-L-arginine decreases defibrillation-induced free radical generation.
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The phosphorylation state of the FIGQY tyrosine of neurofascin determines ankyrin-binding activity and patterns of cell segregation.
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The platelet-derived growth factor receptor-beta phosphorylates and activates G protein-coupled receptor kinase-2. A mechanism for feedback inhibition.
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The role of tyrosine 343 in substrate binding and catalysis by human sulfite oxidase.
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The tyrosine corner: a feature of most Greek key beta-barrel proteins.
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Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues.
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Timing of glycoprotein IIb/IIIa inhibitor use and outcomes among patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention (results from CRUSADE).
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Toxic actions of dinoseb in medaka (Oryzias latipes) embryos as determined by in vivo 31P NMR, HPLC-UV and 1H NMR metabolomics.
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Troponin T and quantitative ST-segment depression offer complementary prognostic information in the risk stratification of acute coronary syndrome patients.
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Tryptophan degradation is associated with risk-taking propensity in methamphetamine users with treated HIV infection.
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Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt.
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Tyrosine cross-linking reveals interfacial dynamics in adeno-associated viral capsids during infection.
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Tyrosine phosphorylation in human neutrophil.
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Tyrosine phosphorylation is a novel pathway for regulation of chloride secretion in shark rectal gland.
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Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants.
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Tyrosine phosphorylation of G protein alpha subunits by pp60c-src.
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Tyrosine phosphorylation of the beta3 cytoplasmic domain mediates integrin-cytoskeletal interactions.
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Tyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor.
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Tyrosine phosphorylation-independent regulation of lipopolysaccharide-mediated response by the transmembrane adaptor protein LAB.
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Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry.
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Upstream use of small-molecule glycoprotein iib/iiia inhibitors in patients with non-ST-segment elevation acute coronary syndromes: a systematic overview of randomized clinical trials.
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Urinary biomarkers of oxidative status.
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Use of glycoprotein IIb/IIIa inhibition plus fibrinolysis in acute myocardial infarction.
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Use of glycoprotein IIb/IIIa inhibitors in primary percutaneous coronary intervention: insights from the APEX-AMI trial.
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Utilizing 18F-fluoroethyltyrosine (FET) positron emission tomography (PET) to define suspected nonenhancing tumor for radiation therapy planning of glioblastoma.
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Vertebrate Lonesome Kinase Regulated Extracellular Matrix Protein Phosphorylation, Cell Shape, and Adhesion in Trabecular Meshwork Cells.
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Would tirofiban have been shown non-inferior to abciximab had the TENACITY trial not been terminated for financial reasons?
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alpha(2)-Macroglobulin from rheumatoid arthritis synovial fluid: functional analysis defines a role for oxidation in inflammation.
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beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis.
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Keywords of People
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Bennett, Vann,
George Barth Geller Distinguished Professor of Molecular Biology,
Duke Cancer Institute
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McLendon, Roger Edwin,
Professor of Pathology,
Pathology
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Middleton, John Paul,
Professor of Medicine,
Medicine, Nephrology
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Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Biomedical Engineering
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Yan, Hai,
Adjunct Professor of Pathology,
Pathology