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Subject Areas on Research
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14-3-3 proteins are part of an abscisic acid-VIVIPAROUS1 (VP1) response complex in the Em promoter and interact with VP1 and EmBP1.
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4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors.
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5' flanking DNA sequences direct cell-specific expression of rat tyrosine hydroxylase.
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5' flanking sequences of the rat tyrosine hydroxylase gene target accurate tissue-specific, developmental, and transsynaptic expression in transgenic mice.
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A common neural circuit mechanism for internally guided and externally reinforced forms of motor learning.
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A logistic regression model for measuring gene-longevity associations.
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A novel basal promoter element is required for expression of the rat tyrosine hydroxylase gene.
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A tyrosine hydroxylase-yellow fluorescent protein knock-in reporter system labeling dopaminergic neurons reveals potential regulatory role for the first intron of the rodent tyrosine hydroxylase gene.
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A word of caution in the use of neuron-specific enolase expression in tumor diagnosis.
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ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus.
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Acute and chronic effects of nicotine on synthesis and storage of catecholamines in the rat adrenal medulla.
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Adrenal medullary storage vesicles of the spontaneously hypertensive rat.
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Adverse benzo[a]pyrene effects on neurodifferentiation are altered by other neurotoxicant coexposures: interactions with dexamethasone, chlorpyrifos, or nicotine in PC12 cells.
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Anatomy of disturbed sleep in pallido-ponto-nigral degeneration.
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Androgen decreases dopamine neurone survival in rat midbrain.
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Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family.
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Associations Between Catecholaminergic and Serotonergic Genes and Persistent Arm Pain Severity Following Breast Cancer Surgery.
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Autofeedback suppression of growth hormone (GH) secretion in transgenic mice expressing a human GH reporter targeted by tyrosine hydroxylase 5'-flanking sequences to the hypothalamus.
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BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells.
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Behavioral and circuit basis of sucrose rejection by Drosophila females in a simple decision-making task.
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Benzo[a]pyrene impairs neurodifferentiation in PC12 cells.
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Beta1-adrenergic receptors maintain fetal heart rate and survival.
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Brain-specific polyA- transcripts are detected in polyA+ RNA: do complex polyA- brain RNAs really exist?
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Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase.
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Catecholamine synthesis, storage and release in adrenal medulla and whole brain during acute and chronic methadone administration.
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Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice.
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Catecholaminergic innervation of the hippocampus in the cynomolgus monkey.
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Catecholamines act via a beta-adrenergic receptor to maintain fetal heart rate and survival.
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Characterization of the axon initial segment of mice substantia nigra dopaminergic neurons.
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Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells.
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Chronic cocaine administration increases CNS tyrosine hydroxylase enzyme activity and mRNA levels and tryptophan hydroxylase enzyme activity levels.
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Cloning and characterization of rat-brain-specific transcripts: rare, brain-specific transcripts and tyrosine hydroxylase.
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Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone.
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Creatine and cyclocreatine attenuate MPTP neurotoxicity.
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DNA regulatory sequences of the rat tyrosine hydroxylase gene direct correct catecholaminergic cell-type specificity of a human growth hormone reporter in the CNS of transgenic mice causing a dwarf phenotype.
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Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice.
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Delays in growth and biochemical development of rat brain caused by maternal methadone administration: are the alterations in synaptogenesis and cellular maturation independent of reduced maternal food intake?
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Development of central and peripheral catecholaminergic systems in rats addicted perinatally to methadone.
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Development of nicotinic responses in the rat adrenal medulla and long-term effects of neonatal nicotine administration.
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Differential expression of the B'beta regulatory subunit of protein phosphatase 2A modulates tyrosine hydroxylase phosphorylation and catecholamine synthesis.
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Differentiation of a catecholaminergic CNS cell line modifies tyrosine hydroxylase transcriptional regulation.
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Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death.
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Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease.
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Effect of 9 -tetrahydrocannabinol on immobilization-induced changes in rat adrenal medullary enzymes.
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Effects of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-induced hemiparkinsonism on the kinematics of a two-dimensional,multijoint arm movement in the rhesus monkey.
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Effects of chronic nicotine administration on the denervated rat adrenal medulla.
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Effects of maternal ethanol ingestion on amine uptake into synaptosomes of fetal and neonatal rat brain.
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Effects of morphine on the rat adrenal medulla.
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Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene.
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Elevation of RNA coding for tyrosine hydroxylase in rat adrenal gland by reserpine treatment and exposure to cold.
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Exposure to methylmercury in utero: effects on biochemical development of catecholamine neurotransmitter systems.
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Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2).
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Genes and longevity: lessons from studies of centenarians.
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High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer.
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High oxygen prevents fetal lethality due to lack of catecholamines.
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Homeostatic mechanisms in dopamine synthesis and release: a mathematical model.
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Identification and cell type specificity of the tyrosine hydroxylase gene promoter.
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Impaired development of central and peripheral catecholamine neurotransmitter systems in preweanling rats treated with alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase.
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Induction of tyrosine hydroxylase in the locus coeruleus of transgenic mice in response to stress or nicotine treatment: lack of activation of tyrosine hydroxylase promoter activity.
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Induction of tyrosine hydroxylase protein and a transgene containing tyrosine hydroxylase 5' flanking sequences by stress in mouse adrenal gland.
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Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells.
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Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells.
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Isolation of two E-box binding factors that interact with the rat tyrosine hydroxylase enhancer.
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Lesioning of the striatum reverses motor asymmetry in the 6-hydroxydopamine rodent model of parkinsonism.
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Loss of response to levodopa in Parkinson's disease and co-occurrence with dementia: role of D3 and not D2 receptors.
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Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import.
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Maturation of the adrenal medulla--IV. Effects of morphine.
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Models of dopaminergic and serotonergic signaling.
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Morphine-reserpine interactions in the adrenal medulla.
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Neonatal methylmercury poisoning in the rat: effects on development of central catecholamine neurotransmitter systems.
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Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.
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Nitric oxide production and regulation of neuronal NOS in tyrosine hydroxylase containing neurons.
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Nrf2-mediated protection against 6-hydroxydopamine.
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Nutritional influences on adrenal chromaffin cell development: comparison with central neurons.
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Oestrogen receptors enhance dopamine neurone survival in rat midbrain.
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PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation.
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Prenatal reserpine administration: permanent changes in adrenal tyrosine hydroxylase and dopamine beta-hydroxylase.
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Prostate-Confined Radiation Decreased Pelvic Ganglia Neuronal Survival and Outgrowth.
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Protection from oxidation enhances the survival of cultured mesencephalic neurons.
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Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3-dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation.
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Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis.
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Quantitative 1H magnetic resonance spectroscopic imaging determines therapeutic immunization efficacy in an animal model of Parkinson's disease.
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Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
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Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase.
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Recurrent interactions between the input and output of a songbird cortico-basal ganglia pathway are implicated in vocal sequence variability.
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Regulated expression of the tyrosine hydroxylase gene by epidermal growth factor.
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Regulation of tyrosine hydroxylase mRNA by glucocorticoid and cyclic AMP in a rat pheochromocytoma cell line. Isolation of a cDNA clone for tyrosine hydroxylase mRNA.
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Regulation of tyrosine hydroxylase mRNA by glucocorticoid and cyclic AMP in a rat pheochromocytoma cell line. Isolation of a cDNA clone for tyrosine hydroxylase mRNA.
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Reserpine-like effects of harmine on isolated adrenal medullary vesicles.
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Role of 14-3-3-mediated p38 mitogen-activated protein kinase inhibition in cardiac myocyte survival.
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Role of carotid body catecholamines in chemoreceptor function.
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Role of glucocorticoids in tuning hindbrain stress integration.
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Role of leptin in fat regulation.
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Role of the midbrain dopaminergic system in modulation of vocal brain activation by social context.
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Sequences that direct rat tyrosine hydroxylase gene expression.
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Sex-specific Disruption of the Prairie Vole Hypothalamus by Developmental Exposure to a Flame Retardant Mixture.
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Studies of dopamine pharmacology in molluscs.
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Surgical management of pheochromocytoma with the use of metyrosine.
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Sympatho-adrenal development in perinatally addicted rats.
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Synthesis and pharmacological evaluation of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for a novel receptor with sigma-like neuromodulatory activity.
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The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter.
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The biological significance of substrate inhibition: a mechanism with diverse functions.
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The cyclic AMP response element directs tyrosine hydroxylase expression in catecholaminergic central and peripheral nervous system cell lines from transgenic mice.
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The functional consequences of genetic variation on tyrosine hydroxylase (TH) expression
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The influences on human longevity by HUMTHO1.STR polymorphism (Tyrosine Hydroxylase gene). A relative risk approach.
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The localization of sensory nerve fibers and receptor binding sites for sensory neuropeptides in canine mesenteric lymph nodes.
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The modular nature of histone deacetylase HDAC4 confers phosphorylation-dependent intracellular trafficking.
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The role of neural input in the effects of morphine on the rat adrenal medulla.
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The roles of 14-3-3 proteins in signal transduction.
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Tissue-specific transcription of the rat tyrosine hydroxylase gene requires synergy between an AP-1 motif and an overlapping E box-containing dyad.
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Trans-synaptic increase in RNA coding for tyrosine hydroxylase in a rat sympathetic ganglion.
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Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP.
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Tyrosine hydroxylase mRNA in the neurons of the tuberoinfundibular region and zona incerta examined after gonadal steroid hormone treatment.
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Tyrosine hydroxylase transcription depends primarily on cAMP response element activity, regardless of the type of inducing stimulus.
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When the checkpoints have gone: insights into Cdc25 functional activation.
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Y+ and y+ L arginine transporters in neuronal cells expressing tyrosine hydroxylase.
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p-Chlorophenylalanine-induced enhancement of the effects of morphine on the adrenal medulla.
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α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration.
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α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration.
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