Urinary Tract Infections

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  Subject Areas on Research

  • A Bundle-Based Approach to Prevent Catheter-Associated Urinary Tract Infections in the Intensive Care Unit. 
  • A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion. 
  • A Tool to Assess the Signs and Symptoms of Catheter-Associated Urinary Tract Infection: Development and Reliability. 
  • A comparative study of the mannose-resistant and mannose-sensitive haemagglutinins of Escherichia coli isolated from urinary tract infections. 
  • A comparison of antibiotic prophylaxis regimens to decrease the risk of post-procedure urinary tract infection after onabotulinum toxin A injection. 
  • A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections. 
  • A model to predict risk of postpartum infection after Caesarean delivery. 
  • A multicenter comparative trial of three-day norfloxacin vs ten-day sulfamethoxazole and trimethoprim for the treatment of uncomplicated urinary tract infections. 
  • A multicenter, double-blind, trimethoprim-sulfamethoxazole controlled study of enoxacin in the treatment of patients with complicated urinary tract infections. 
  • A multifaceted intervention to reduce rates of catheter-associated urinary tract infections in a resource-limited setting. 
  • A novel role for renal epithelial cells and the medullary sodium gradient in the local immune response. 
  • A sublingual nanofiber vaccine to prevent urinary tract infections. 
  • ACR Appropriateness Criteria® Acute Pyelonephritis: 2022 Update. 
  • ACR Appropriateness Criteria® Hematospermia. 
  • ACR Appropriateness Criteria® Recurrent Lower Urinary Tract Infections in Females. 
  • ACR Appropriateness Criteria® Urinary Tract Infection-Child. 
  • Accessory phallic urethra in adult female. 
  • Accuracy of microscopic urine analysis and chest radiography in patients with severe sepsis and septic shock. 
  • An evaluation of metrics for assessing catheter-associated urinary tract infections (CAUTIs): A statewide comparison. 
  • Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis. 
  • Antibiotic resistance in urinary isolates of Escherichia coli from college women with urinary tract infections. 
  • Antibiotic use and the prevention and management of infectious complications in stone disease. 
  • Anticholinergic therapy vs. onabotulinumtoxina for urgency urinary incontinence. 
  • Assessing the relative burden of hospital-acquired infections in a network of community hospitals. 
  • Assessing ureteral patency using 10% dextrose cystoscopy fluid: evaluation of urinary tract infection rates. 
  • Association between ICAM-1 Gly-Arg polymorphism and renal parenchymal scarring following childhood urinary tract infection. 
  • Association between positive urine cultures and necrotizing enterocolitis in a large cohort of hospitalized infants. 
  • Augmentation and substitution enterocystoplasty. 
  • Avoiding Cardiovascular Collapse: Pediatric Cutaneous Mastocytosis and Anesthetic Challenges. 
  • Bacteremia in sickle hemoglobinopathies. 
  • Bacterial penetration of bladder epithelium through lipid rafts. 
  • Bad bugs: antibiotic-resistant bacteriuria in pregnancy and risk of pyelonephritis. 
  • Baseline Characteristics, Evaluation, and Management of Women With Complaints of Recurrent Urinary Tract Infections. 
  • Benign prostatic hyperplasia. New concepts in the 1990s. 
  • Beyond death and graft survival-Variation in outcomes after liver transplant. Results from the NSQIP transplant beta phase. 
  • Blind-ending branches of bifid ureters. 
  • Braden score may be associated with time to onset of catheter-associated urinary tract infection in high-risk patients: Lessons learned from a root cause analysis tool. 
  • Canephron® N (BNO 1045) may be Non-inferior to Single-dose Fosfomycin in Reducing the Need for Additional Antibiotics to Treat Women with Presumptive Uncomplicated Urinary Tract Infections. 
  • Cefepime/Enmetazobactam for Complicated Urinary Tract Infections. 
  • Characteristics of Women with Urinary Tract Infection in Pregnancy. 
  • Clinical outcomes after ureteroscopic lithotripsy in patients who initially presented with urosepsis: matched pair comparison with elective ureteroscopy. 
  • Colonial morphology of staphylococci on Memphis agar: phase variation of slime production, resistance to beta-lactam antibiotics, and virulence. 
  • Commensal Urinary Lactobacilli Inhibit Major Uropathogens In Vitro With Heterogeneity at Species and Strain Level. 
  • Comparison of low-dose cinoxacin therapy and placebo in the prevention of recurrent urinary tract infections. 
  • Comparison of metrics used to track central-line-associated bloodstream infections (CLABSIs) and catheter-associated urinary tract infections (CAUTIs) across a regional network. 
  • Comparison of non-intensive care unit (ICU) versus ICU rates of catheter-associated urinary tract infection in community hospitals. 
  • Contribution of urinary tract infection to the burden of febrile illnesses in young children in rural Kenya. 
  • Controlled trial comparing co-trimoxazole and methenamine hippurate in the prevention of recurrent urinary tract infections. 
  • Cost effectiveness of management strategies for urinary tract infections: results from randomised controlled trial. 
  • Cost-effectiveness of bacteriuria screening before urogynecologic surgery. 
  • Costs and consequences of universal sibling screening for vesicoureteral reflux: decision analysis. 
  • Cranberry Capsules do not Appear to Reduce Bacteriuria and Pyuria in Elderly Women Residing in Nursing Homes. 
  • Cranberry use among pediatric nephrology patients. 
  • Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells. 
  • Development and pilot testing of computerized order entry algorithms for geriatric problems in nursing homes. 
  • Diagnosis of urinary tract infections: need for a reflective rather than reflexive approach. 
  • Dipsticks and diagnostic algorithms in urinary tract infection: development and validation, randomised trial, economic analysis, observational cohort and qualitative study. 
  • Do Mixed-Flora Preoperative Urine Cultures Matter? 
  • Do not abandon amphotericin B as an antifungal bladder irrigant. 
  • Does a Recent Urinary Tract Infection Increase the Risk of Postprocedure Urinary Tract Infection After Onabotulinum Toxin A? 
  • Does nonpayment for hospital-acquired catheter-associated urinary tract infections lead to overtesting and increased antimicrobial prescribing? 
  • Does this woman have an acute uncomplicated urinary tract infection? 
  • Drug-induced meningitis. A case involving trimethoprim-sulfamethoxazole. 
  • Economic and radiation costs of initial imaging approaches after a child's first febrile urinary tract infection. 
  • Editorial Comment. 
  • Editorial comment. 
  • Effectiveness of five different approaches in management of urinary tract infection: randomised controlled trial. 
  • Efficacy of antibiotic prophylaxis in children with vesicoureteral reflux: systematic review and meta-analysis. 
  • Endoscopic management of symptomatic caliceal diverticula: a retrospective comparison of percutaneous nephrolithotripsy and ureteroscopy. 
  • Enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder. 
  • Envisioning Future Urinary Tract Infection Diagnostics. 
  • Escherichia coli global gene expression in urine from women with urinary tract infection. 
  • Evaluation of an evidence-based, nurse-driven checklist to prevent hospital-acquired catheter-associated urinary tract infections in intensive care units. 
  • External validation of an ED protocol for reflex urine culture cancelation. 
  • Extra-intestinal manifestations of salmonella infections. 
  • FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae. 
  • Fluconazole therapy for experimental cryptococcosis and candidiasis in the rabbit. 
  • Fluoroquinolones and the Risk of Achilles Tendon Disorders: Update on a Neglected Complication. 
  • Framing the picture: Impact of radiographic imaging on parental vesicoureteral reflux management preferences. 
  • Gallstone ileus: revisiting surgical outcomes using National Surgical Quality Improvement Program data. 
  • Genetic, biochemical, and structural studies of biogenesis of adhesive pili in bacteria. 
  • Genitourinary complications of sickle cell disease. 
  • Giant cell interstitial pneumonia associated with nitrofurantoin. 
  • High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis. 
  • HipBA-promoter structures reveal the basis of heritable multidrug tolerance. 
  • How we manage urinary tract infections in children. 
  • Hydrogen peroxide instillations into the urinary drainage bag: should we or shouldn't we? 
  • Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine. 
  • Impact of Changes to the National Healthcare Safety Network (NHSN) Definition on Catheter-Associated Urinary Tract Infection (CAUTI) Rates in Intensive Care Units at an Academic Medical Center. 
  • Impact of Education and Data Feedback on Antibiotic Prescribing for Urinary Tract Infections in the Emergency Department: An Interrupted Time-Series Analysis. 
  • Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients. 
  • Impact of therapy and strain type on outcomes in urinary tract infections caused by carbapenem-resistant Klebsiella pneumoniae. 
  • Implementing a urinary tract infection clinical practice guideline in an ambulatory urgent care practice. 
  • Improving Traditional Registrational Trial End Points: Development and Application of a Desirability of Outcome Ranking End Point for Complicated Urinary Tract Infection Clinical Trials. 
  • Inability of encapsulated Klebsiella pneumoniae to assemble functional type 1 fimbriae on their surface. 
  • Incidence of Urinary Tract Infections in Newborns with Spina Bifida-Is Antibiotic Prophylaxis Necessary? 
  • Incidence of adverse events after uterosacral colpopexy for uterovaginal and posthysterectomy vault prolapse. 
  • Infections after kidney transplantation. Does age matter? 
  • Infections after upper extremity allotransplantation: a worldwide population cohort study, 1998-2017. 
  • Influence of berberine sulfate on synthesis and expression of Pap fimbrial adhesin in uropathogenic Escherichia coli. 
  • Innate and adaptive immune responses in the urinary tract. 
  • Interplay between vesicoureteric reflux and kidney infection in the development of reflux nephropathy in mice. 
  • Intravesical instillation of gentamicin sulfate: in vitro, rat, canine, and human studies. 
  • Is There a Correlation Between Infection Control Performance and Other Hospital Quality Measures? 
  • Is it time to abandon the use of amphotericin B bladder irrigation? 
  • Is there a need for medical evaluation and treatment of nephrolithiasis in the "age of lithotripsy"? 
  • Kidney α-intercalated cells and lipocalin 2: defending the urinary tract. 
  • Lactobacillus crispatus Limits Bladder Uropathogenic E. coli Infection by Triggering a Host Type I Interferon Response. 
  • Local induction of bladder Th1 responses to combat urinary tract infections. 
  • Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain-specific antibody to confer protection against experimental urinary tract infection. 
  • Long-term efficacy of simple behavioral therapy for daytime wetting in children. 
  • Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules. 
  • Lower Urinary Pathogens: Do More Pathogenic Bacteria Increase the Risk of Pyelonephritis? 
  • Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues. 
  • Morbidity following lower extremity fractures in men with spinal cord injury. 
  • Multiple gonococcal opacity proteins are expressed during experimental urethral infection in the male. 
  • Multiple nosocomial infections. An incidence study. 
  • National Imaging and Antibiotic Practice Patterns in Children Presenting With Urinary Tract Infection to Community Practices: Little Impact From the American Academy of Pediatrics Guidelines? 
  • Navigating reflex urine culture practices in community hospitals: Need for a validated approach. 
  • New persistent opioid use after acute opioid prescribing in pregnancy: a nationwide analysis. 
  • Nosocomial infections in the elderly. Increased risk per hospital day. 
  • Nosocomial infections within the first month of solid organ transplantation. 
  • Nurse staffing and adverse events in hospitalized children. 
  • Nurse-Initiated Telephone Follow Up after Ureteroscopic Stone Surgery. 
  • Ofloxacin, a new broad-spectrum fluoroquinolone. Results from a Multicenter, National Comparative Activity Surveillance Study. The Ofloxacin Surveillance Group. 
  • OnabotulinumtoxinA vs Sacral Neuromodulation on Refractory Urgency Urinary Incontinence in Women: A Randomized Clinical Trial. 
  • Optimizing reflex urine cultures: Using a population-specific approach to diagnostic stewardship. 
  • Oral antibiotics to prevent postoperative urinary tract infection: a randomized controlled trial. 
  • Outcomes of Ureteroscopic Stone Treatment in Patients With Spinal Cord Injury. 
  • Overtreatment of presumed urinary tract infection in older women presenting to the emergency department. 
  • Overview of first-line amikacin therapy for urologic infections. 
  • P pili in uropathogenic E. coli are composite fibres with distinct fibrillar adhesive tips. 
  • Patient Preferences for Medications in Managing Type 2 Diabetes Mellitus: A Discrete Choice Experiment. 
  • Pediatric urolithiasis. 
  • Pediatric urolithiasis: medical and surgical management. 
  • Pediatric-specific antimicrobial susceptibility data and empiric antibiotic selection. 
  • Peeing pentraxins. 
  • Perioperative Complications in Minimally Invasive Sacrocolpopexy Versus Transvaginal Mesh in the Management of Pelvic Organ Prolapse: Analysis of a National Multi-institutional Dataset. 
  • Persisting uropathogenic Escherichia coli lineages show signatures of niche-specific within-host adaptation mediated by mobile genetic elements. 
  • Possible tobramycin delirium. 
  • Post-surgical infections and perioperative antibiotics usage in pediatric genitourinary procedures. 
  • Posttransplant infection in enteric versus bladder-drained simultaneous pancreas-kidney transplant recipients. 
  • Predicting the Risk of Breakthrough Urinary Tract Infections: Primary Vesicoureteral Reflux. 
  • Predicting urine culture results by dipstick testing and phase contrast microscopy. 
  • Predominant bacteria and patterns of antibiotic susceptibility in urinary tract infection in children with spina bifida. 
  • Preoperative biological therapy and short-term outcomes of abdominal surgery in patients with inflammatory bowel disease. 
  • Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age. 
  • Prospective randomized double-blind comparison of moxalactam and tobramycin in treatment of urinary tract infections. 
  • Protection against Escherichia coli-induced urinary tract infections with hybridoma antibodies directed against type 1 fimbriae or complementary D-mannose receptors. 
  • Quicker determination of antibiotic susceptibility in urinary tract infections. 
  • Radiation dose and screening for vesicoureteral reflux. 
  • Recent changes in the NHSN definition for UTI: for better AND worse. 
  • Recurrent urinary tract infections and intermittent left flank pain in young woman. 
  • Refractory urgency urinary incontinence treatment in women: impact of age on outcomes and complications. 
  • Reliability of Symptoms and Dipstick for Postoperative Catheter-Associated Urinary Tract Infections. 
  • Renal scarring and urinary tract infection after successful endoscopic correction of vesicoureteral reflux. 
  • Renal transplantation in children. 
  • Resolution rate of isolated low-grade hydronephrosis diagnosed within the first year of life. 
  • Risk Factors Associated With Recurrent Urinary Tract Infection in Neurogenic Bladders Managed by Clean Intermittent Catheterization. 
  • Role of TGF-beta1 in renal parenchymal scarring following childhood urinary tract infection. 
  • Role of bacterial lectins in urinary tract infections. Molecular mechanisms for diversification of bacterial surface lectins. 
  • Serious infections among unselected patients with ST-elevation myocardial infarction treated with contemporary primary percutaneous coronary intervention. 
  • Single-center analysis of infectious complications in older adults during the first year after kidney transplantation. 
  • Single-dose amoxicillin therapy with follow-up urine culture. Effective initial management for acute uncomplicated urinary tract infections. 
  • Spectrum of excess mortality due to carbapenem-resistant Klebsiella pneumoniae infections. 
  • Steering between Scylla and Charybdis: Picking out the optimum time of double-J stent removal following renal transplantation. 
  • Strategies of antiretroviral therapy in adults. 
  • Strategies to prevent catheter-associated urinary tract infections in acute care hospitals. 
  • Striving to Reach the Optimal Measure for Catheter-Associated Urinary Tract Infection (CAUTI): Moving to Catheter Harm. 
  • Struvite calculi. 
  • Sustained reduction in catheter-associated urinary tract infections using multi-faceted strategies led by champions: A quality improvement initiative. 
  • TLR4-initiated and cAMP-mediated abrogation of bacterial invasion of the bladder. 
  • Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat Female Recurrent Urinary Tract Infection. 
  • The Association of Previous Prostate Biopsy Related Complications and the Type of Complication with Patient Compliance with Rebiopsy Scheme. 
  • The Disproportionate Impact of Coronavirus Disease 2019 (COVID-19) Pandemic on Healthcare-Associated Infections in Community Hospitals: Need for Expanding the Infectious Disease Workforce. 
  • The Effect of Catheterization on Susceptibility of Uropathogens After Pelvic Reconstructive Surgery. 
  • The Impact of 2015 NHSN Catheter-associated Urinary Tract Infection (CAUTI) Definition Change on Central Line-associated Bloodstream Infection (CLABSI) Rates and CLABSI Prevention Efforts at an Academic Medical Center. 
  • The evolution of catheter-associated urinary tract infection (CAUTI): Is it time for more inclusive metrics? 
  • The evolving landscape of healthcare-associated infections: recent advances in prevention and a road map for research. 
  • The female urinary microbiome in urgency urinary incontinence. 
  • The histopathology of vesical diverticula. 
  • The impact of glycemic control and diabetes mellitus on perioperative outcomes after total joint arthroplasty. 
  • The nature of immune responses to urinary tract infections. 
  • The network approach for prevention of healthcare-associated infections: long-term effect of participation in the Duke Infection Control Outreach Network. 
  • The potential impact of excluding funguria from the surveillance definition of catheter-associated urinary tract infection. 
  • The trial to reduce antimicrobial use in nursing home residents with Alzheimer's disease and other dementias: study protocol for a cluster randomized controlled trial. 
  • The use of amphotericin B in nosocomial fungal infection. 
  • Total shoulder arthroplasty in patients with HIV infection: complications, comorbidities, and trends. 
  • Treatment for urinary tract infection after midurethral sling: a retrospective study comparing patients who receive short-term postoperative catheterization and patients who pass a void trial on the day of surgery. 
  • Trends in Intravenous Antibiotic Duration for Urinary Tract Infections in Young Infants. 
  • Two-Year Outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for Refractory Urgency Urinary Incontinence: A Randomized Trial. 
  • Ubiquitination of Innate Immune Regulator TRAF3 Orchestrates Expulsion of Intracellular Bacteria by Exocyst Complex. 
  • Urinary infection in male patients with acute nephrolithiasis: should we hunt for a rare bird? 
  • Urinary tract erosions after synthetic pubovaginal slings: diagnosis and management strategy. 
  • Urinary tract infection after stroke: A narrative review. 
  • Urinary tract infection concordance with positive blood and cerebrospinal fluid cultures in the neonatal intensive care unit. 
  • Urinary tract infection due to laboratory-acquired Escherichia coli: relation to virulence. 
  • Urinary tract infections in long-term care residents. 
  • Urinary tract infections in meningioma patients: analysis of risk factors and outcomes. 
  • Urinary tract pathogens and antimicrobial sensitivity patterns in children in Ibadan, Nigeria. 
  • Urodynamic abnormalities in neurologically normal children with micturition dysfunction. 
  • Urologic sepsis/shock. 
  • Uropathogenic Escherichia coli subverts mitochondrial metabolism to enable intracellular bacterial pathogenesis in urinary tract infection. 
  • Use of silver in the prevention and treatment of infections: silver review. 
  • Using statistical process control charts to measure changes from a nurse-driven protocol to remove urinary catheters. 
  • Variation in US hospital emergency department admission rates by clinical condition. 
  • Variation in definitions of urinary tract infections in spina bifida patients: a systematic review. 
  • Vesicoureteral reflux in children with urachal anomalies. 
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  Keywords of People

  • Cohen-Wolkowiez, Michael, Kiser-Arena Distinguished Professor, Pediatrics, Infectious Diseases
  • McConnell, Eleanor Schildwachter, Associate Professor in the School of Nursing, School of Nursing
  • Moehring, Rebekah, Associate Professor of Medicine, Medicine, Infectious Diseases
  • Routh, Jonathan Charles, Paul H. Sherman, M.D. Distinguished Associate Professor of Surgery, Pediatrics