Urokinase-Type Plasminogen Activator
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Subject Areas on Research
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A comparison of thrombolytic therapy with operative revascularization in the initial treatment of acute peripheral arterial ischemia.
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Accelerated plasminogen activator dose regimens for coronary thrombolysis. The TAMI-7 Study Group.
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Acute management of intracranial hemorrhage in patients receiving thrombolytic therapy: case reports.
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Acute peripheral arterial occlusion: predictors of success in catheter-directed thrombolytic therapy.
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Adoption of thrombolytic therapy in the management of acute myocardial infarction.
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Association of plasma urokinase-type plasminogen activator and its receptor with clinical outcome in patients undergoing radical cystectomy for transitional cell carcinoma of the bladder.
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Autocrine regulation of growth stimulation in human epithelial ovarian carcinoma by serine-proteinase-catalysed release of the urinary-type-plasminogen-activator N-terminal fragment.
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Brachial approach to emergency cardiac catheterization during thrombolytic therapy for acute myocardial infarction. TAMI Study Group.
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Burn Injury Alters Epidermal Cholinergic Mediators and Increases HMGB1 and Caspase 3 in Autologous Donor Skin and Burn Margin.
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Calcium modulates the expression of urokinase plasminogen activator and plasminogen activator inhibitor 2 by human keratinocytes.
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Catabolism of human tissue plasminogen activator in mice.
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Catheter-related sepsis refractory to antibiotics treated successfully with adjunctive urokinase infusion.
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Changes in standard electrocardiographic ST-segment elevation predictive of successful reperfusion in acute myocardial infarction.
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Characterization of keratinocyte plasminogen activator inhibitors and demonstration of the prevention of pemphigus IgG-induced acantholysis by a purified plasminogen activator inhibitor.
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Cisplatin but not BCNU inhibits urokinase-type plasminogen activator levels in human glioblastoma cell lines in vitro.
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Co-expression of urokinase with haptoglobin in human carcinomas.
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Combinatorial mutagenesis of the reactive site region in plasminogen activator inhibitor I.
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Comparison of plasminogen binding and activation on extracellular matrices produced by vascular smooth muscle and endothelial cells.
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Comparison of streptokinase, urokinase, and recombinant tissue plasminogen activator in an in vitro model of venous thrombolysis.
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Complete atrioventricular block complicating inferior wall acute myocardial infarction treated with reperfusion therapy. TAMI Study Group.
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Coordinate expression of urinary-type plasminogen activator and its receptor accompanies malignant transformation of the ovarian surface epithelium.
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Coronary arterial thrombolysis with combined infusion of recombinant tissue-type plasminogen activator and urokinase in patients with acute myocardial infarction.
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Coronary bypass surgery improves global and regional left ventricular function following thrombolytic therapy for acute myocardial infarction. TAMI Study Group.
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Determinants of the need for early acute intervention in patients treated conservatively after thrombolytic therapy for acute myocardial infarction. TAMI-5 Study Group.
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Differential mechanisms of failure of autogenous and non-autogenous bypass conduits: an assessment following successful graft thrombolysis.
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Effects of thrombolytic regimen, early catheterization, and predischarge angiographic variables on six-week left ventricular function. The TAMI Investigators. Thrombolysis and Angioplasty in Acute Myocardial Infarction.
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Elevated urokinase-type plasminogen activator level and bleeding in amyloidosis: case report and literature review.
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Embolization of cardiac mural thrombus: complication of intraarterial fibrinolysis.
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Epidermal plasminogen activator is abnormal in cutaneous lesions.
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Evaluation of combination thrombolytic therapy and timing of cardiac catheterization in acute myocardial infarction. Results of thrombolysis and angioplasty in myocardial infarction--phase 5 randomized trial. TAMI Study Group.
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Expression of plasminogen activator enzymes in psoriatic epidermis.
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Expression of plasminogen activators in basal cell carcinoma.
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Extravascular fibrin formation and dissolution in synovial tissue of patients with osteoarthritis and rheumatoid arthritis.
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Fate of patients with acute myocardial infarction with patency of the infarct-related vessel achieved with successful thrombolysis versus rescue angioplasty.
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Human epidermal plasminogen activator. Characterization, localization, and modulation.
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Hyaluronan fragments induce plasminogen activator inhibitor-1 and inhibit urokinase activity in mouse alveolar macrophages: a potential mechanism for impaired fibrinolytic activity in acute lung injury.
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Imbalanced matriptase pericellular proteolysis contributes to the pathogenesis of malignant B-cell lymphomas.
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Importance of early and complete reperfusion to achieve myocardial salvage after thrombolysis in acute myocardial infarction.
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Indices of reperfusion in patients with acute myocardial infarction using characteristics of the CK-MB time-activity curve.
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Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.
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Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).
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Involvement of urokinase-type plasminogen activator in acantholysis induced by pemphigus IgG.
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Keratinocyte urokinase-type plasminogen activator is secreted as a single chain precursor.
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Kinetic analysis of the effects of glycosaminoglycans and lipoproteins on urokinase-mediated plasminogen activation.
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Lack of impact of early catheterization and fibrin specificity on bleeding complications after thrombolytic therapy. The TAMI Study Group.
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Lipoprotein (a) regulates plasmin generation and inhibition.
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Management of infrainguinal occluded vein bypasses with a combined approach of thrombolysis and surveillance. A prospective study.
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Mechanical versus chemical thrombolysis: an in vitro differentiation of thrombolytic mechanisms.
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Mechanism of benefit of combination thrombolytic therapy for acute myocardial infarction: a quantitative angiographic and hematologic study.
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Migrating keratinocytes express urokinase-type plasminogen activator.
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Modulation of in vitro invasion of human glioblastoma cells by urokinase-type plasminogen activator receptor antibody.
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Multivessel coronary artery disease: a key predictor of short-term prognosis after reperfusion therapy for acute myocardial infarction. Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group.
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Myocardial infarction with minimal coronary atherosclerosis in the era of thrombolytic reperfusion. The Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group.
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New murine cell line derived from a spontaneous lung tumor induces paraneoplastic syndromes.
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Noninvasive detection of reperfusion after thrombolysis based on serum creatine kinase MB changes and clinical variables. TAMI 7 Study Group. Thrombolysis and Angioplasty in Myocardial Infarction.
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Outcome of patients with diabetes mellitus and acute myocardial infarction treated with thrombolytic agents. The Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group.
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Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA.
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Percutaneous transhepatic recanalization and thrombolysis of the superior mesenteric vein.
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Pharmacomechanical thrombolysis of experimental pulmonary emboli. Rapid low-dose intraembolic therapy.
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Plasminogen acceleration of urokinase thrombolysis.
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Plasminogen activator inhibitor: a regulator of ancrod-induced fibrin deposition in rabbits.
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Primary upper-extremity deep venous thrombosis.
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Proteolysis of von Willebrand factor after thrombolytic therapy in patients with acute myocardial infarction.
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Provocative angiography in patients with gastrointestinal hemorrhage of obscure origin.
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Purification and characterization of a fibrinolytic enzyme of Bacillus subtilis DC33, isolated from Chinese traditional Douchi.
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Rapid visualization of massive pulmonary emboli utilizing intravascular ultrasound.
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Ratio of ST-segment and myoglobin slopes to estimate myocardial salvage during thrombolytic therapy for acute myocardial infarction.
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Recurrent thrombosis of the superior vena cava associated with activated protein C resistance: imaging findings.
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Regulation of plasminogen activator inhibitor-1 and urokinase by hyaluronan fragments in mouse macrophages.
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Results of high dose intravenous urokinase for acute myocardial infarction.
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Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using an in vitro matrigel model.
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SAMP14, a novel, acrosomal membrane-associated, glycosylphosphatidylinositol-anchored member of the Ly-6/urokinase-type plasminogen activator receptor superfamily with a role in sperm-egg interaction.
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Safety and efficacy of extended urokinase infusion plus stent deployment for treatment of obstructed, older saphenous vein grafts.
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Safety and efficacy of limited-dose tissue plasminogen activator in acute vascular occlusion.
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Secretion of extracellular matrix-degrading proteinases is increased in epithelial ovarian carcinoma.
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Selective infusion of thrombolytic therapy in the acute myocardial infarct-related coronary artery as an alternative to rescue percutaneous transluminal coronary angioplasty.
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Serum protein expression predicts recurrence in patients with early-stage lung cancer after resection.
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Significance of a coronary artery with thrombolysis in myocardial infarction grade 2 flow "patency" (outcome in the thrombolysis and angioplasty in myocardial infarction trials). Thrombolysis and Angioplasty in Myocardial Infarction Study Group.
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Soluble Urokinase Receptor and Acute Kidney Injury.
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Specific binding of urinary-type plasminogen activator (u-PA) to vitronectin and its role in mediating u-PA-dependent adhesion of U937 cells.
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Structural and functional characterization of the inhibition of urokinase by alpha 2-macroglobulin.
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Studies on the medical treatment of deep vein thrombosis.
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THP-1 macrophage membrane-bound plasmin activity is up-regulated by transforming growth factor-beta 1 via increased expression of urokinase and the urokinase receptor.
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The addition of urinary urokinase-type plasminogen activator to urinary nuclear matrix protein 22 and cytology improves the detection of bladder cancer.
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The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients.
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The effect of divalent cations on the conformation and function of human plasminogen.
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The effects of intermittent pneumatic compression during cesarean delivery on fibrinolysis.
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The importance of the preactivation peptide in the two-stage mechanism of human plasminogen activation.
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The use of intraaortic balloon pumping as an adjunct to reperfusion therapy in acute myocardial infarction. The Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group.
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Thrombolysis in acute peripheral arterial occlusion: predictors of immediate success.
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Thrombolytic therapy for women with myocardial infarction: is there a gender gap? Thrombolysis and Angioplasty in Myocardial Infarction Study Group.
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Thrombus lysis by uPA, scuPA and tPA is regulated by plasma TAFI.
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Tissue factor is the receptor for plasminogen type 1 on 1-LN human prostate cancer cells.
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Treatment of dural sinus thrombosis by urokinase infusion.
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Two urokinase dose regimens in native arterial and graft occlusions: initial results of a prospective, randomized clinical trial.
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Urinary levels of urokinase-type plasminogen activator and its receptor in the detection of bladder carcinoma.
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Urokinase infusion and stenting of older saphenous vein grafts.
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Urokinase plasminogen activator is immunocytochemically detectable in squamous cell but not basal cell carcinomas.
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Urokinase treatment of neonatal aortoiliac thrombosis caused by umbilical artery catheterization: a case report.
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Usefulness of a pericardial friction rub after thrombolytic therapy during acute myocardial infarction in predicting amount of myocardial damage. The TAMI Study Group.
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mRNA for tissue-type plasminogen activator is present in lesional epidermis from patients with psoriasis, pemphigus, or bullous pemphigoid, but is not detected in normal epidermis.
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