Uterus

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  Subject Areas on Research

  • 17-hydroxyprogesterone caproate for women with congenital uterine anomalies: does it impact the risk of recurrent preterm birth? 
  • A demonstration in vitro of luteolytic activity in pig uterine flushings. 
  • A double-blind randomized study on the effects of red clover isoflavones on the endometrium. 
  • A look at uterine wound healing through a histopathological study of uterine scars. 
  • A randomized comparison of home uterine activity monitoring in the outpatient management of women treated for preterm labor. 
  • A technique for serial spermatozoa collection in mice. 
  • Additive estrogenic activities of a binary mixture of 2',4',6'-trichloro- and 2',3',4',5'-tetrachloro-4-biphenylol. 
  • Adrenergic receptors. 
  • Adrenomedullin expression in rat uterus is correlated with plasma estradiol. 
  • Adrenomedullin improves fertility and promotes pinopodes and cell junctions in the peri-implantation endometrium. 
  • Allergic reactions to penicillin during in vitro fertilization and intrauterine insemination. 
  • Alpha adrenergic receptor subtypes in rabbit uterus: mediation of myometrial contraction and regulation by estrogens. 
  • Alpha-adrenergic receptor identification by (3H)dihydroergocryptine binding. 
  • Alpha-adrenergic receptor subtypes: quantitative assessment by ligand binding. 
  • Amniotic fluid embolism presenting after uterine manipulation under general anesthesia: a case with a positive outcome. 
  • An assay for alpha-adrenergic receptor subtypes using [3H]dihydroergocryptine. 
  • Analysis of messenger ribonucleic acid and protein for the ligands and receptors of the platelet-derived growth factor signaling pathway in the placenta, extraembryonic membranes, and uterus during the latter half of murine gestation. 
  • Anatomic changes in the pelvis after uncomplicated vaginal delivery: evaluation with serial MR imaging. 
  • Anchor cell invasion into the vulval epithelium in C. elegans. 
  • Ancient transposable elements transformed the uterine regulatory landscape and transcriptome during the evolution of mammalian pregnancy. 
  • Are implantation and pregnancy outcome impaired in diethylstilbestrol-exposed women after in vitro fertilization and embryo transfer? 
  • Association Between Enlarged Genital Hiatus and Composite Surgical Failure After Vaginal Hysterectomy With Uterosacral Ligament Suspension. 
  • Basement membrane sliding and targeted adhesion remodels tissue boundaries during uterine-vulval attachment in Caenorhabditis elegans. 
  • Benign metastasizing leiomyoma: a rare cause of multiple pulmonary nodules. 
  • Benign prostatic hypertrophy and uterine leiomyomas: analogous or dissimilar diseases? 
  • Bilateral uterosacral ligament vaginal vault suspension with site-specific endopelvic fascia defect repair for treatment of pelvic organ prolapse. 
  • Biological and biochemical consequences of global deletion of exon 3 from the ER alpha gene. 
  • Bisphenol A exposure alters developmental gene expression in the fetal rhesus macaque uterus. 
  • Bisphenol A interacts with the estrogen receptor alpha in a distinct manner from estradiol. 
  • CD26 inhibition enhances allogeneic donor-cell homing and engraftment after in utero hematopoietic-cell transplantation. 
  • CNS location of uterine-related neurons revealed by trans-synaptic tracing with pseudorabies virus and their relation to estrogen receptor-immunoreactive neurons. 
  • CRISPLD2 is a target of progesterone receptor and its expression is decreased in women with endometriosis. 
  • Case series: Combined spinal epidural anesthesia for Cesarean delivery and ex utero intrapartum treatment procedure. 
  • Cell death and proliferation and its relation to collagen degradation in uterine involution of rat. 
  • Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors. 
  • Cesarean delivery: a reconsideration of terminology. 
  • Characterization of purified rabbit uterine renin: influence of pregnancy on uterine inactive renin. 
  • Characterization of the tissue regression process in the uterus of older mice as apoptotic by the presence of Tp30, an isoform of terminin. 
  • Characterization of uterine NK cells in women with infertility or recurrent pregnancy loss and associated endometriosis. 
  • Chemokine ligand and receptor expression in the pregnant uterus: reciprocal patterns in complementary cell subsets suggest functional roles. 
  • Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid. 
  • Circulating angiogenic factors and abnormal uterine artery Doppler velocimetry in the second trimester. 
  • Cocaine blocks extraneuronal uptake of norepinephrine by the pregnant human uterus. 
  • Comparison of covalently and physically cross-linked polyethylene glycol-based hydrogels for the prevention of postoperative adhesions in a rat model. 
  • Comparison of intracervical, intrauterine, and intratubal techniques for donor insemination. 
  • Comparison of prostaglandin F2alpha and hypertonic saline for induction of midtrimester abortion. 
  • Comparison of the ultrasonic scalpel to CO2 laser and electrosurgery in terms of tissue injury and adhesion formation in a rabbit model. 
  • Complications of cesarean section: role of transperineal US. 
  • Congenital Uterine Malformation by Experts (CUME): better criteria for distinguishing between normal/arcuate and septate uterus? 
  • Congenital Uterine Malformation by Experts (CUME): diagnostic criteria for T-shaped uterus. 
  • Contemporary views on female pelvic anatomy. 
  • Continuous extraovular administration of prostaglandin F2alpha for midtrimester abortion. 
  • Creatine kinase activity as an indicator of unopposed estrogen action in the mouse uterus associated with anti-progesterone treatment. 
  • Determination of subtype selectivity of alpha-adrenergic antagonists: comparison of selective and nonselective radioligands. 
  • Development of a research agenda for uterine artery embolization: proceedings from a multidisciplinary research consensus panel. 
  • Development of an ER action indicator mouse for the study of estrogens, selective ER modulators (SERMs), and Xenobiotics. 
  • Development of the human female reproductive tract. 
  • Diagnosis and Management of Congenital Uterine Anomalies in Pregnancy. 
  • Dietary galactose inhibits GDF-9 mediated follicular development in the rat ovary. 
  • Dihydroergocryptine binding and alpha-adrenoreceptors in smooth muscle. 
  • Disruption of the mouse oestrogen receptor gene: resulting phenotypes and experimental findings. 
  • Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone. 
  • Dynamic reciprocity between cells and their microenvironment in reproduction. 
  • E2-induced degradation of uterine insulin receptor substrate-2: requirement for an IGF-I-stimulated, proteasome-dependent pathway. 
  • ELECTROPHORETIC SEPARATION OF HYDROLYTIC ENZYMES OF THE FEMALE RAT REPRODUCTIVE TRACT. 
  • Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. 
  • Early estrogen action: concomitant stimulations within two minutes of nuclear RNA synthesis and uptake of RNA precursor by the uterus. 
  • Early estrogen action: nuclear synthesis and accumulation of protein correlated with enhancement of two DNA-dependent RNA polymerase activities. 
  • Ectopic pregnancy: ultrasonographic diagnosis and interpretive pitfalls. 
  • Editorial: Selectivity in beta-adrenergic responses: clinical implications. 
  • Effect of Vaginal Mesh Hysteropexy vs Vaginal Hysterectomy With Uterosacral Ligament Suspension on Treatment Failure in Women With Uterovaginal Prolapse: A Randomized Clinical Trial. 
  • Effect of an intrauterine contraceptive device on uterine motility in the rat. 
  • Effect of exogenous dehydroepiandrosterone upon the fetoplacental biosynthesis of estrogens and its effect upon uterine blood flow in the term pregnant ewe. 
  • Effects of D-ring substituents on antiprogestational (antagonist) and progestational (agonist) activity of 11 beta-aryl steroids. 
  • Effects of diazoxide and beta adrenergic drugs on spontaneous and induced uterine activity in the pregnant baboon. 
  • Effects of genistein or soy milk during late gestation and lactation on adult uterine organization in the rat. 
  • Effects of prostaglandin F 2 , oxytocin, and ethanol on the uterus of the pregnant baboon. 
  • Embolic microspheres within ovarian arterial vasculature after uterine artery embolization. 
  • Embryo transfer to the uterus or the fallopian tube after in vitro fertilization yields similar results. 
  • Enhanced Uterine Contractility and Stillbirth in Mice Lacking G Protein-Coupled Receptor Kinase 6 (GRK6): Implications for Oxytocin Receptor Desensitization. 
  • Enhancement of human hematopoiesis by mast cell growth factor in human-sheep chimeras created by the in utero transplantation of human fetal hematopoietic cells. 
  • Environmentally relevant xenoestrogen tissue concentrations correlated to biological responses in mice. 
  • Epidermal growth factor receptor expression in normal and malignant endometrium. 
  • Epidermal growth factor replaces estrogen in the stimulation of female genital-tract growth and differentiation. 
  • Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function. 
  • Estradiol replacement enhances cocaine-stimulated locomotion in female C57BL/6 mice through estrogen receptor alpha. 
  • Estrogen receptor-alpha (ER-alpha) and defects in uterine receptivity in women. 
  • Estrogen regulation of aquaporins in the mouse uterus: potential roles in uterine water movement. 
  • Estrogen up-regulates cyclooxygenase-2 via estrogen receptor in human uterine microvascular endothelial cells. 
  • Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism. 
  • Evaluation of a recombinant yeast cell estrogen screening assay. 
  • Evidence for depression of nuclear protein synthesis and concomitant stimulation of nuclear RNA synthesis during early estrogen action. 
  • Experimental study of the effect of diethylstilbestrol on the development of the human female reproductive tract. 
  • Female steroid hormones and target cell nuclei. 
  • Flavonoids. 8. Synthesis and antifertility and estrogen receptor binding activities of coumarins and delta3-isoflavenes. 
  • For sperm--is closer to the egg an advantage or liability? 
  • Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: implication of oral bacteria in preterm birth. 
  • Gabapentin for Perioperative Pain Management for Uterine Aspiration: A Randomized Controlled Trial. 
  • Gene expression profiling reveals progesterone-mediated cell cycle and immunoregulatory roles of Hoxa-10 in the preimplantation uterus. 
  • Generation and characterization of a complete null estrogen receptor alpha mouse using Cre/LoxP technology. 
  • Genetic insights into biological mechanisms governing human ovarian ageing. 
  • Giant uterine leiomyoma mimicking pregnancy. 
  • Gynecological abnormalities following allogeneic bone marrow transplantation. 
  • Helicobacter infection decreases reproductive performance of IL10-deficient mice. 
  • Hemicentin-mediated type IV collagen assembly strengthens juxtaposed basement membrane linkage. 
  • Heterogeneity of radioligand binding to alpha-adrenergic receptors. Analysis of guanine nucleotide regulation of agonist binding in relation to receptor subtypes. 
  • Human uterine NK cells interact with uterine macrophages via NKG2D upon stimulation with PAMPs. 
  • Hydronephrosis: A Rare Presentation of Uterine Didelphys with Obstructed Hemivagina and Ipsilateral Renal Anomaly. 
  • Hydrops fetalis associated with idiopathic arterial calcification. 
  • Identification of alpha-adrenergic receptors in uterine smooth muscle membranes by [3H]dihydroergocryptine binding. 
  • Immunohistochemical expression of TAG-72 in normal and malignant endometrium: correlation of antigen expression with estrogen receptor and progesterone receptor levels. 
  • Immunologic challenges of human reproduction: an evolving story. 
  • Immunological approach to the study of hormone action: regulation of the phosphorylation state of protein phosphatase inhibitor-1 by hormones. 
  • Impact of toll-like receptor 4 deficiency on the response to uterine ischemia/reperfusion in mice. 
  • Imprinted expression of the canine IGF2R, in the absence of an anti-sense transcript or promoter methylation. 
  • Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus. 
  • Induction of labor with oral prostaglandin E2. 
  • Inhibitory action of a new sympathomimetic amino (DU-21220) on the nongravid uterus. 
  • Integrative analysis of the forkhead box A2 (FOXA2) cistrome for the human endometrium. 
  • Intelligibility of sentences recorded from the uterus of a pregnant ewe and from the fetal inner ear. 
  • Intrauterine anesthesia for gynecologic procedures: a systematic review. 
  • Intrauterine group A streptococcal infections are exacerbated by prostaglandin E2. 
  • Intravital imaging of mouse embryos. 
  • Investigation of antiestrogenic properties of unleaded gasoline in female mice. 
  • Is total laparoscopic hysterectomy with longer operative time associated with a decreased benefit compared with total abdominal hysterectomy? 
  • KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance. 
  • Lactoferrin expression in the mouse reproductive tract during the natural estrous cycle: correlation with circulating estradiol and progesterone. 
  • Local Control and Use of External Beam Parametrial Boost in the Era of Image-Guided Brachytherapy for Locally Advanced Cervical Cancer. 
  • Low resistance Doppler waveforms with retained products of conception: potential for diagnostic confusion with gestational trophoblastic disease. 
  • Management strategies for Mayer-Rokitansky-Kuster-Hauser related vaginal agenesis: a cost-effectiveness analysis. 
  • Mechanical Signaling and Extracellular Matrix in Uterine Fibroids. 
  • Mechanism of estrogen action: early transcriptional and translational events. 
  • Meeting Report of the 13th Congress of the International Society of Vascularized Composite Allotransplantation. 
  • Mid-trimester abortion induced by intravaginal administration of prostaglandin E2 suppositories. 
  • Midtrimester abortion induced by serial intramuscular injections of 15(S)-15-methyl-prostaglandin F2alpha. 
  • Midtrimester abortion induced with a single intra-amniotic instillation of prostaglandin F2 alpha. 
  • Modulation of estrogen receptor levels in mouse uterus by protein kinase C isoenzymes. 
  • Molecular mechanisms of development of the human fetal female reproductive tract. 
  • Movement of cynomolgus and rhesus monkey spermatozoa collected from the lower female reproductive tract. 
  • Mullerian dysgenesis: a critical review of the literature. 
  • Multimaterial three-dimensional printing in brachytherapy: Prototyping teaching tools for interstitial and intracavitary procedures in cervical cancers. 
  • Native Tissue Prolapse Repairs: Comparative Effectiveness Trials. 
  • Nonhuman primate models of intrauterine cytomegalovirus infection. 
  • Observations of tissue response to acoustic radiation force: opportunities for imaging. 
  • Operations and pelvic muscle training in the management of apical support loss (OPTIMAL) trial: design and methods. 
  • Overexpression of HER-2/neu in endometrial cancer is associated with advanced stage disease. 
  • Oxygenated norethindrone derivatives from incubation with beagle liver. Structure, synthesis, and biological activity. 
  • Pelvic normal tissue contouring guidelines for radiation therapy: a Radiation Therapy Oncology Group consensus panel atlas. 
  • Perforated uterus with displacement of intrauterine device. 
  • Pinopodes: Recent advancements, current perspectives, and future directions. 
  • Plasmodium falciparum parasitaemia in the first half of pregnancy, uterine and umbilical artery blood flow, and foetal growth: a longitudinal Doppler ultrasound study. 
  • Potentiation of diethylstilbestrol-induced alterations in the female mouse reproductive tract by transforming growth factor-alpha transgene expression. 
  • Preconception Evaluation Before In Vitro Fertilization. 
  • Preeclampsia risk in women exposed in utero to diethylstilbestrol. 
  • Pregnancy and estradiol decrease GTPase activity in the guinea pig uterine artery. 
  • Pregnancy lactogens in the rat conceptus and fetus: circulating levels, distribution of binding, and expression of receptor messenger ribonucleic acid. 
  • Progesterone Metabolites Produced by Cytochrome P450 3A Modulate Uterine Contractility in a Murine Model. 
  • Progesterone receptor signaling in the initiation of pregnancy and preservation of a healthy uterus. 
  • Prospective data collection of a new procedure by a specialty society: the FIBROID registry. 
  • Pseudoaneurysm of the uterine artery after an uncomplicated spontaneous vaginal delivery. 
  • Randomized controlled trial investigating the effect of transcervical papaverine and bupivacaine on postoperative analgesia following laparoscopic sterilization. 
  • Rates of preterm birth in multiparous women with congenital uterine anomalies. 
  • Reactivity of epidermal growth factor receptor monoclonal antibodies with human uterine tissues. 
  • Regulation of rabbit myometrial alpha adrenergic receptors by estrogen and progesterone. 
  • Relaxant effect of diazepam on uterine muscle. 
  • Relocation of ectopic pregnancy to the uterine cavity: a dream or a reality? 
  • Repair of the traumatically ruptured gravid uterus. A report of two cases resulting in viable pregnancies. 
  • Reports From Four International Clinical Trials for Cancers of the Cervix, Uterus and Vulva, and a New Guideline for Cervical Cancer. 
  • Reproductive tract biology: Of mice and men. 
  • Response of xenografts of developing human female reproductive tracts to the synthetic estrogen, diethylstilbestrol. 
  • SIRT1 plays an important role in implantation and decidualization during mouse early pregnancy. 
  • SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh. 
  • SPARTEINE AND OXYTOCIN: IN-VITRO COMPARISON ON PREGNANT-UTERUS MUSCLE. 
  • Sarcoidosis of the uterus. 
  • Selectivity of dobutamine for adrenergic receptor subtypes: in vitro analysis by radioligand binding. 
  • Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy. 
  • Shift in S-layer protein expression responsible for antigenic variation in Campylobacter fetus. 
  • Simplified pain-control protocol after uterine artery embolization. 
  • Smoothelin-like 1 protein regulates myosin phosphatase-targeting subunit 1 expression during sexual development and pregnancy. 
  • Soybean isoflavones improve cardiovascular risk factors without affecting the reproductive system of peripubertal rhesus monkeys. 
  • Sperm transport in the reproductive tract of the female rabbit: II. The sustained phase of transport. 
  • Stress affects uterine receptivity through an ovarian-independent pathway. 
  • Stress and placental resistance measured by Doppler ultrasound in early and mid-pregnancy. 
  • Sublingual aerosol nitroglycerin for uterine relaxation in attempted external version. 
  • Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice. 
  • Synthesis of 11 beta,13 beta- and 13 beta,16 beta-propano steroids: probes of hormonal activity. 
  • Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion. 
  • Teratogenic effects of clomiphene, tamoxifen, and diethylstilbestrol on the developing human female genital tract. 
  • The Design of a Randomized Trial of Vaginal Surgery for Uterovaginal Prolapse: Vaginal Hysterectomy With Native Tissue Vault Suspension Versus Mesh Hysteropexy Suspension (The Study of Uterine Prolapse Procedures Randomized Trial). 
  • The effect of berotec (Th 1165a) on spontaneous and induced uterine activity in the pregnant baboon. 
  • The effect of ethyl alcohol on isolated human myometrium. 
  • The fetal allograft revisited: does the study of an ancient invertebrate species shed light on the role of natural killer cells at the maternal-fetal interface? 
  • The gene encoding vitamin K-dependent anticoagulant protein S is expressed in multiple rabbit organs as demonstrated by northern blotting, in situ hybridization, and immunohistochemistry. 
  • The immunomodulatory roles of macrophages at the maternal-fetal interface. 
  • The impact of surgeon volume on perioperative adverse events in women undergoing minimally invasive hysterectomy for the large uterus. 
  • The increasing use of robot-assisted approach for hysterectomy results in decreasing rates of abdominal hysterectomy and traditional laparoscopic hysterectomy. 
  • The inhibitory effect of diazoxide in normal term labor. 
  • The progesterone receptor regulates implantation, decidualization, and glandular development via a complex paracrine signaling network. 
  • The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure. 
  • The relaxant action of ritodrine, a sympathomimetic amine, on the uterus during term labor. 
  • The relaxant effect of diazoxide on isolated gravid and nongravid human myometrium. 
  • The relaxant effect of diazoxide on nongravid human myometrium in vivo. 
  • Three-dimensional structures of uterine elastic fibers: scanning electron microscopic studies. 
  • Three-dimensional ultrasound diagnosis of T-shaped uterus is associated with adverse pregnancy outcomes after embryo transfer. 
  • Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues. 
  • Time-course imaging of rat embryos in utero with magnetic resonance microscopy. 
  • Timing and irreversibility of Müllerian duct inhibition in the embryonic reproductive tract of the human male. 
  • Tissue interactions and estrogenic response during human female fetal reproductive tract development. 
  • Tissue remodeling in the female reproductive tract--a complex process becomes more complex: the role of Hox genes. 
  • Transcription profiling of estrogen target genes in young and old mouse uterus. 
  • Transforming growth factors beta 1, beta 2, and beta 3 messenger RNA and protein expression in mouse uterus and vagina during estrogen-induced growth: a comparison to other estrogen-regulated genes. 
  • Type I interferons instigate fetal demise after Zika virus infection. 
  • UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity 
  • Ultrasound of the postpartum uterus. Prediction of retained placental tissue. 
  • Up-regulated cytotrophoblast DOCK4 contributes to over-invasion in placenta accreta spectrum. 
  • Use of Sepharose 4B for preparative scale fractionation of eukaryotic messenger RNA's. 
  • Uterine NK cell education: Learning the ropes in pregnancy. 
  • Uterine artery embolization for treatment of leiomyomata: long-term outcomes from the FIBROID Registry. 
  • Uterine artery embolization: what more do we need to know? 
  • Uterine blood flow: periodic fluctuations of its rate during pregnancy. 
  • Uterine exteriorization compared with in situ repair for Cesarean delivery: a systematic review and meta-analysis. 
  • Uterine exteriorization versus in situ repair in Cesarean delivery: a systematic review and meta-analysis. 
  • Uterine leiomyomata in relation to insulin-like growth factor-I, insulin, and diabetes. 
  • Uterine relaxant properties of bradykinin in vitro. 
  • Vaginal Uterosacral Ligament Suspension: A Retrospective Cohort of Absorbable and Permanent Suture Groups. 
  • Vaginal adenosis in women born prior to the diethylstilbestrol era. 
  • Vaginal and cervical abnormalities, including clear-cell adenocarcinoma, related to prenatal exposure to stilbestrol. 
  • WNK1 regulates uterine homeostasis and its ability to support pregnancy. 
  • Wedge metroplasty for the septate uterus: an update. 
  • [3H]WB4101--caution about its role as an alpha-adrenergic subtype selective radioligand. 
  • β-Arrestin mediates oxytocin receptor signaling, which regulates uterine contractility and cellular migration. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Cell Biology