Vaccines

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  Subject Areas on Research

  • 10-year research update review: the epidemiology of child and adolescent psychiatric disorders: II. Developmental epidemiology. 
  • A need for effective adjuvants. 
  • A real-time PCR assay to identify and discriminate among wild-type and vaccine strains of varicella-zoster virus and herpes simplex virus in clinical specimens, and comparison with the clinical diagnoses. 
  • Active immunotherapy with transiently transfected cytokine-secreting tumor cells inhibits breast cancer metastases in tumor-bearing animals. 
  • Addressing the vaccine confidence gap. 
  • Advisory Committee on Immunization Practices recommended immunization schedule for adults aged 19 years or older - United States, 2014. 
  • Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model. 
  • Anti-idiotypic antibodies as vaccine candidates. The immune network. 
  • Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay. 
  • Association of vaccine-related attitudes and beliefs between parents and health care providers. 
  • B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. 
  • Biomaterial strategies for generating therapeutic immune responses. 
  • Broadly Neutralizing Antibodies and the Development of Vaccines. 
  • Cell-mediated immune responses to vaccine peptides derived from the circumsporozoite protein of Plasmodium falciparum. 
  • Cellular immune responses in neonates. 
  • Chemistry. Nanomaterials for drug delivery. 
  • Childhood immunization programs: an analysis of policy issues. 
  • Commentary: Vaccines-Protecting Health and Saving Lives. 
  • Comparing data mining methods on the VAERS database. 
  • Comparison of multiple vaccine vectors in a single heterologous prime-boost trial. 
  • Controversies in immunization. 
  • Cysteine-tailed class I-binding peptides bind to CpG adjuvant and enhance primary CTL responses. 
  • Cytokines: the future of intranasal vaccine adjuvants. 
  • Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies. 
  • Development and application of a multiplex assay for the simultaneous measurement of antibody responses elicited by common childhood vaccines. 
  • Dry powder vaccines for mucosal administration: critical factors in manufacture and delivery. 
  • Effect of antipyretic analgesics on immune responses to vaccination. 
  • Effect of endotoxin and alum adjuvant vaccine on peanut allergy. 
  • Engineering challenges for brain tumor immunotherapy. 
  • Enhanced dendritic cell antigen presentation in RNA-based immunotherapy. 
  • Evaluating associations between vaccine response and malnutrition, gut function, and enteric infections in the MAL-ED cohort study: methods and challenges. 
  • Eye-tracking evidence shows that non-fit messaging impacts attention, attitudes and choice. 
  • Future trends in managing hepatitis C. 
  • Future vaccines and a global perspective. 
  • Global progress in the control of diarrheal diseases. 
  • Gradated assembly of multiple proteins into supramolecular nanomaterials. 
  • Guidelines for immunizations in patients with inflammatory bowel disease. 
  • HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. 
  • Herpes simplex virus (HSV)-mediated ICAM-1 gene transfer abrogates tumorigenicity and induces anti-tumor immunity. 
  • History Lesson: Vaccine Trials in the Classroom. 
  • Immunization and MS: a summary of published evidence and recommendations. 
  • Immunosenescence of ageing. 
  • Immunotherapy of cancer using cytokine gene-modified tumor vaccines. 
  • Infections in Pregnancy and the Role of Vaccines. 
  • Maternal benefits of immunization during pregnancy. 
  • Maternal immunization: opportunities for scientific advancement. 
  • Mercury Exposure and Poor Nutritional Status Reduce Response to Six Expanded Program on Immunization Vaccines in Children: An Observational Cohort Study of Communities Affected by Gold Mining in the Peruvian Amazon. 
  • Mercury, vaccines, and autism: one controversy, three histories. 
  • Modulating atherothrombosis: is there a place for vaccines in global prevention strategies? 
  • Mucosal immunity to infection with implications for vaccine development. 
  • Mucosal vaccine development for botulinum intoxication. 
  • Mucosal vaccine targeting improves onset of mucosal and systemic immunity to botulinum neurotoxin A. 
  • Naturally acquired antibodies to sporozoites do not prevent malaria: vaccine development implications. 
  • New findings on nicotine addiction and treatment. 
  • No Shot: US Vaccine Prices And Shortages. 
  • Non-reassuring fetal status: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data. 
  • Non-replicating mucosal and systemic vaccines: quantitative and qualitative differences in the Ag-specific CD8(+) T cell population in different tissues. 
  • Nucleic acid aptamers as adjuncts to vaccine development. 
  • Paired Toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12. 
  • Parental vaccine refusal in Wisconsin: a case-control study. 
  • Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. 
  • Polymer hydrogels: Chaperoning vaccines. 
  • Postimmunization reactions. 
  • Potentiation of cell-mediated immune responses directed against P. falciparum sporozoite peptide vaccine by immunomodulators. 
  • Prenatal immunization education the pediatric prenatal visit and routine obstetric care. 
  • Presidential address. Reflections on the 1970s and a look to the future. 
  • Priming, boosting, measuring. 
  • Principles of Anti-infective Dosing in Pregnancy. 
  • Promoting Vaccine Confidence. 
  • Reply to Gantt et al., "Higher Expectations for a Vaccine To Prevent Congenital Cytomegalovirus Infection". 
  • Research on vaccines during pregnancy: protocol design and assessment of safety. 
  • Research on vaccines during pregnancy: reference values for vital signs and laboratory assessments. 
  • Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV. 
  • Some state vaccination laws contribute to greater exemption rates and disease outbreaks in the United States. 
  • The HIV-positive traveler. 
  • The Impact of the Gut Microbiota on Humoral Immunity to Pathogens and Vaccination in Early Infancy. 
  • The allure and peril of hematopoietic stem cell transplantation: overcoming immune challenges to improve success. 
  • The challenges of checkpoint inhibition in the treatment of multiple myeloma. 
  • The fragility of the U.S. vaccine supply. 
  • Titrating T-cell epitopes within self-assembled vaccines optimizes CD4+ helper T cell and antibody outputs. 
  • Transduction of human melanoma cells with the gamma interferon gene enhances cellular immunity. 
  • UK announces cash boost for vaccines and free health care in poor countries. 
  • Underimmunization at discharge from the neonatal intensive care unit. 
  • Unique cellular and humoral immunogenicity profiles generated by aerosol, intranasal, or parenteral vaccination in rhesus macaques. 
  • Update on immunizations in adults. 
  • Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. 
  • Vaccinations for pregnant women. 
  • Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates. 
  • Vaccine adjuvants: Softness makes it better. 
  • Vaccine coverage and adherence to EPI schedules in eight resource poor settings in the MAL-ED cohort study. 
  • Vaccine knowledge and practices of primary care providers of exempt vs. vaccinated children. 
  • Vaccine safety: medical contraindications, myths, and risk communication. 
  • Vaccine storage practices in primary care physician offices: assessment and intervention. 
  • Vaccine-preventable diseases in pregnancy. 
  • [Emerging adenovirus threats: should China develop a vaccine-oriented prevention strategy?]. 
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  Keywords of People

  • Bonsignori, Mattia, Associate Professor in Medicine, Duke Human Vaccine Institute
  • Johnson-Weaver, Brandi, Research Scientist, Pathology
  • Kelsoe, Garnett H., James B. Duke Distinguished Professor of Immunology, Immunology
  • Lee, Walter T, Associate Professor of Surgery, Radiation Oncology
  • Vasudevan, Lavanya, Assistant Professor in Family Medicine and Community Health, Family Medicine and Community Health