Vancomycin

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  Subject Areas on Research

  • A Phase 3, Randomized, Double-Blind, Multicenter Study To Evaluate the Safety and Efficacy of Intravenous Iclaprim versus Vancomycin for Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed To Be Due to Gram-Positive Pathogens (REVIVE-2 Study). 
  • A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of Intravenous Iclaprim Vs Vancomycin for the Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed to be Due to Gram-Positive Pathogens: REVIVE-1. 
  • A Phase II Randomized, Double-blind, Multicenter Study to Evaluate Efficacy and Safety of Intravenous Iclaprim Versus Vancomycin for the Treatment of Nosocomial Pneumonia Suspected or Confirmed to be Due to Gram-positive Pathogens. 
  • A Pooled Analysis of the Safety and Efficacy of Iclaprim Versus Vancomycin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Patients With Intravenous Drug Use: Phase 3 REVIVE Studies. 
  • A pooled analysis of patients with wound infections in the Phase 3 REVIVE trials: randomized, double-blind studies to evaluate the safety and efficacy of iclaprim versus vancomycin for treatment of acute bacterial skin and skin structure infections. 
  • A randomized Phase 2 trial of telavancin versus standard therapy in patients with uncomplicated Staphylococcus aureus bacteremia: the ASSURE study. 
  • AUA-recommended Antibiotic Prophylaxis for Primary Penile Implantation Results in a Higher, Not Lower, Risk for Postoperative Infection: A Multicenter Analysis. 
  • An open-label, pragmatic, randomized controlled clinical trial to evaluate the comparative effectiveness of daptomycin versus vancomycin for the treatment of complicated skin and skin structure infection. 
  • Anaphylactic/anaphylactoid reactions during cardiac surgery. 
  • Antibiotic eluting chitosan glycerophosphate implant in the setting of acute bacterial sinusitis: a rabbit model. 
  • Antibiotic prophylaxis for hemodialysis access placement. 
  • Antibiotic-induced accumulation of lipid II synergizes with antimicrobial fatty acids to eradicate bacterial populations. 
  • Antistaphylococcal β-Lactams versus Vancomycin for Treatment of Infective Endocarditis Due to Methicillin-Susceptible Coagulase-Negative Staphylococci: a Prospective Cohort Study from the International Collaboration on Endocarditis. 
  • Assessment of telavancin minimal inhibitory concentrations by revised broth microdilution method in phase 3 complicated skin and skin-structure infection clinical trial isolates. 
  • Bloodstream Infection Due to Vancomycin-resistant Enterococcus Is Associated With Increased Mortality After Hematopoietic Cell Transplantation for Acute Leukemia and Myelodysplastic Syndrome: A Multicenter, Retrospective Cohort Study. 
  • CAMERA2 - combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial. 
  • CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. 
  • CANVAS 2: the second Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. 
  • Chronic Inflammation After YAG Capsulotomy. 
  • Clinical characteristics and outcomes of diabetic patients with Staphylococcus aureus bacteremia and endocarditis. 
  • Clinical identifiers of complicated Staphylococcus aureus bacteremia. 
  • Clinical management of Staphylococcus aureus bacteremia: a review. 
  • Clostridium difficile cure with fecal microbiota transplantation in a child with Pompe disease: a case report. 
  • Clostridium difficile infection and treatment in the pediatric inflammatory bowel disease population. 
  • Combined medical and surgical management of severe pseudomembranous colitis. 
  • Community-Acquired Pneumonia in Adults: Diagnosis and Management. 
  • Comparative efficacy of antibiotics for the treatment of acute bacterial skin and skin structure infections (ABSSSI): a systematic review and network meta-analysis. 
  • Comparison of the incidence of vancomycin-induced nephrotoxicity in hospitalized patients with and without concomitant piperacillin-tazobactam. 
  • Controlled Release of Vancomycin and Tigecycline from an Orthopaedic Implant Coating Prevents Staphylococcus aureus Infection in an Open Fracture Animal Model. 
  • Dalbavancin or oritavancin for skin infections. 
  • Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus. 
  • Daptomycin versus vancomycin plus gentamicin for treatment of bacteraemia and endocarditis due to Staphylococcus aureus: subset analysis of patients infected with methicillin-resistant isolates. 
  • Development of a standardized screening method for detection of vancomycin-resistant enterococci. 
  • Drug-induced linear IgA bullous dermatosis in a patient with a vancomycin-impregnated cement spacer. 
  • Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial. 
  • Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial. 
  • Effect of vancomycin serum trough levels on outcomes in patients with nosocomial pneumonia due to Staphylococcus aureus: a retrospective, post hoc, subgroup analysis of the Phase 3 ATTAIN studies. 
  • Effectiveness of Vancomycin or Beta-Lactam Therapy in Ampicillin-Susceptible Enterococcus spp. Bloodstream Infections. 
  • Effectiveness of antimicrobial guidelines for community-acquired pneumonia in children. 
  • Efficacy and safety of fidaxomicin compared with oral vancomycin for the treatment of adults with Clostridium difficile-associated diarrhea: data from the OPT-80-003 and OPT-80-004 studies. 
  • Endocapsular hypopyon: a clinical sign of localized endophthalmitis. 
  • Endocarditis caused by Staphylococcus aureus with reduced susceptibility to vancomycin. 
  • Enterococcal endocarditis in the beginning of the 21st century: analysis from the International Collaboration on Endocarditis-Prospective Cohort Study. 
  • Excessive use of vancomycin: a successful intervention strategy at an academic medical center. 
  • Experience with intrawound vancomycin powder for posterior cervical fusion surgery. 
  • Experience with intrawound vancomycin powder for spinal deformity surgery. 
  • Future challenges and treatment of Staphylococcus aureus bacteremia with emphasis on MRSA. 
  • Generation of ramoplanin-resistant Staphylococcus aureus. 
  • Granulicatella Adiacens as an Unusual Cause of Microbial Keratitis and Endophthalmitis: A Case Series and Literature Review. 
  • Heparin neutralization with methylene blue, hexadimethrine, or vancomycin after cardiopulmonary bypass. 
  • Hepatic dysfunction following busulfan and cyclophosphamide myeloablation: a retrospective, multicenter analysis. 
  • Histamine release by vancomycin: a mechanism for hypotension in man. 
  • History of antibiotics: from fluoroquinolones to daptomycin (Part 2). 
  • Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attributes of catalytic efficiency, stereoselectivity and regulation with implications for function. 
  • Host gene expression profiling and in vivo cytokine studies to characterize the role of linezolid and vancomycin in methicillin-resistant Staphylococcus aureus (MRSA) murine sepsis model. 
  • Impact of Oral Metronidazole, Vancomycin, and Fidaxomicin on Host Shedding and Environmental Contamination With Clostridioides difficile. 
  • Impact of Reduced Preincision Antibiotic Infusion Time on Surgical Site Infection Rates: A Retrospective Cohort Study. 
  • In Vivo Efficacy of a ´93Smart´94 Antimicrobial Implant Coating 
  • In vivo activity and pharmacokinetics of ziracin (SCH27899), a new long-acting everninomicin antibiotic, in a murine model of penicillin-susceptible or penicillin-resistant pneumococcal pneumonia. 
  • Infected bilomas in liver transplant recipients, incidence, risk factors and implications for prevention. 
  • Infective endocarditis due to Staphylococcus aureus: 59 prospectively identified cases with follow-up. 
  • Influence of vancomycin minimum inhibitory concentration on the outcome of methicillin-susceptible Staphylococcus aureus left-sided infective endocarditis treated with antistaphylococcal β-lactam antibiotics: a prospective cohort study by the International Collaboration on Endocarditis. 
  • Initial low-dose gentamicin for Staphylococcus aureus bacteremia and endocarditis is nephrotoxic. 
  • Inpatient Antimicrobial Stewardship in Pediatrics: A Systematic Review. 
  • Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection. 
  • Intra-Articular Vancomycin Powder Eliminates Methicillin-Resistant S. aureus in a Rat Model of a Contaminated Intra-Articular Implant. 
  • Is it time to replace vancomycin in the treatment of methicillin-resistant Staphylococcus aureus infections? 
  • Letter to the editor regarding: "Effectiveness of local vancomycin powder to decrease surgical site infections: a meta-analysis" by Chiang et al. 
  • Leuconostoc bacteremia in pediatric patients with short bowel syndrome: case series and review. 
  • Local Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: A Multicenter, Randomized, Controlled Trial (VANCO Study). 
  • MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony Variants In Vitro within Macrophages and Endothelial Cells during Prolonged Vancomycin Exposure. 
  • Massive pulmonary pseudotumor. 
  • Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. 
  • Molecular characterization and multilaboratory evaluation of Enterococcus faecalis ATCC 51299 for quality control of screening tests for vancomycin and high-level aminoglycoside resistance in enterococci. 
  • Mortality and time to extubation in severe hospital-acquired pneumonia. 
  • Natural product glycosyltransferases: properties and applications. 
  • Neisseria gonorrhoeae strains inhibited by vancomycin in selective media and correlation with auxotype. 
  • No survival benefit with empirical vancomycin therapy for coagulase-negative staphylococcal bloodstream infections in infants. 
  • Of Rats and Men: a Translational Model To Understand Vancomycin Pharmacokinetic/Toxicodynamic Relationships. 
  • Optimizing therapy for methicillin-resistant Staphylococcus aureus bacteremia. 
  • Outcome of Staphylococcus aureus bacteremia according to compliance with recommendations of infectious diseases specialists: experience with 244 patients. 
  • Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies. 
  • Partial Component Exchange of a Non-Infected Inflatable Penile Prosthesis is Associated With a Higher Complication Rate. 
  • Perioperative Antibiotic Prophylaxis in Total Joint Arthroplasty: A Single Dose Is as Effective as Multiple Doses. 
  • Phenotypic and genotypic characteristics of persistent methicillin-resistant Staphylococcus aureus bacteremia in vitro and in an experimental endocarditis model. 
  • Pooled analysis of the phase 3 REVIVE trials: randomised, double-blind studies to evaluate the safety and efficacy of iclaprim versus vancomycin for treatment of acute bacterial skin and skin-structure infections. 
  • Predictors of agr dysfunction in methicillin-resistant Staphylococcus aureus (MRSA) isolates among patients with MRSA bloodstream infections. 
  • Presence of genes encoding the panton-valentine leukocidin exotoxin is not the primary determinant of outcome in patients with complicated skin and skin structure infections due to methicillin-resistant Staphylococcus aureus: results of a multinational trial. 
  • Prevention and treatment of nosocomial sepsis in the NICU. 
  • Prophylactic use of intraoperative vancomycin powder and postoperative infection: an analysis of microbiological patterns in 1200 consecutive surgical cases. 
  • Randomized Controlled Noninferiority Trial Comparing Daptomycin to Vancomycin for the Treatment of Complicated Skin and Skin Structure Infections in an Observation Unit. 
  • Reduced susceptibility of Staphylococcus aureus to vancomycin and platelet microbicidal protein correlates with defective autolysis and loss of accessory gene regulator (agr) function. 
  • Relationship between Vancomycin MIC and Virulence Gene Expression in Clonal Complexes of Methicillin-Susceptible Staphylococcus aureus Strains Isolated from Left-Sided Endocarditis. 
  • Relative risks of ventriculostomy infection and morbidity. 
  • Removal of a well-fixed metal-metal hip resurfacing acetabular component. 
  • Reply to DiNubile. 
  • Reply to Parra-Ruiz. 
  • Resistant enterococci: a prospective study of prevalence, incidence, and factors associated with colonization in a university hospital. 
  • Risk of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) acquisition during ambulance transport: A retrospective propensity-score-matched cohort analysis. 
  • Sequential prophylactic oral and empiric once-daily parenteral antibiotics for neutropenia and fever after high-dose chemotherapy and autologous bone marrow support. 
  • Short-course therapy for catheter-associated Staphylococcus aureus bacteremia. 
  • Single-dose oritavancin in the treatment of acute bacterial skin infections. 
  • Single-dose oritavancin versus 7-10 days of vancomycin in the treatment of gram-positive acute bacterial skin and skin structure infections: the SOLO II noninferiority study. 
  • Staphylococcus aureus bloodstream infections: definitions and treatment. 
  • Staphylococcus sciuri peritonitis in a patient on peritoneal dialysis. 
  • Stevens-Johnson syndrome induced by the cross-reactivity between teicoplanin and vancomycin. 
  • Studies on the epidemiology of antibiotic-associated Clostridium difficile colitis. 
  • Successful management of orbital cellulitis and temporary visual loss after blepharoplasty. 
  • Suppression of Clostridium difficile by normal hamster cecal flora and prevention of antibiotic-associated cecitis. 
  • Surgical infection prophylaxis prior to left ventricular assist device implantation: A survey of clinical practice. 
  • Surgical site infection prophylaxis strategies for cardiothoracic surgery: a decision-analytic model. 
  • Surgical site infections following bariatric surgery in community hospitals: a weighty concern? 
  • Sustained release of antibiotics from injectable and thermally responsive polypeptide depots. 
  • TD-1792 versus vancomycin for treatment of complicated skin and skin structure infections. 
  • Telavancin for Acute Bacterial Skin and Skin Structure Infections, a Post Hoc Analysis of the Phase 3 ATLAS Trials in Light of the 2013 FDA Guidance. 
  • Telavancin for hospital-acquired pneumonia: clinical response and 28-day survival. 
  • Telavancin for the treatment of hospital-acquired pneumonia: findings from the ATTAIN studies. 
  • Telavancin hospital-acquired pneumonia trials: impact of Gram-negative infections and inadequate Gram-negative coverage on clinical efficacy and all-cause mortality. 
  • Telavancin versus standard therapy for treatment of complicated skin and skin structure infections caused by gram-positive bacteria: FAST 2 study. 
  • Telavancin versus standard therapy for treatment of complicated skin and soft-tissue infections due to gram-positive bacteria. 
  • Telavancin versus vancomycin for bacteraemic hospital-acquired pneumonia. 
  • Telavancin versus vancomycin for hospital-acquired pneumonia due to gram-positive pathogens. 
  • Telavancin versus vancomycin for the treatment of complicated skin and skin-structure infections caused by gram-positive organisms. 
  • The Effect of Intrapartum Vancomycin on Vaginal Group B Streptococcus Colony Counts. 
  • The Emperor's New Clothes: PRospective Observational Evaluation of the Association Between Initial VancomycIn Exposure and Failure Rates Among ADult HospitalizEd Patients With Methicillin-resistant Staphylococcus aureus Bloodstream Infections (PROVIDE). 
  • The Use of a Novel Antimicrobial Implant Coating In Vivo to Prevent Spinal Implant Infection. 
  • Topical Vancomycin for Surgical Prophylaxis in Pediatric Craniofacial Surgeries. 
  • Topical vancomycin for surgical prophylaxis in non-instrumented pediatric spinal surgeries. 
  • Topical vancomycin surgical prophylaxis in pediatric open craniotomies: an institutional experience. 
  • Treatment of vancomycin-resistant enterococci, with a focus on quinupristin-dalfopristin. 
  • Uncovering the Harms of Treating Clostridioides difficile Colonization. 
  • Unilateral shoulder swelling in a preterm neonate. 
  • Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis-dependent patients with methicillin-susceptible Staphylococcus aureus bacteremia. 
  • VanA rectal swab screening as a predictor of subsequent vancomycin-resistant enterococcal bloodstream infection in critically ill adults. 
  • Vancomycin Heteroresistance and Clinical Outcomes in Bloodstream Infections Caused by Coagulase-Negative Staphylococci. 
  • Vancomycin and adverse drug reactions. 
  • Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections. 
  • Vancomycin minimum inhibitory concentration and outcome in patients with Staphylococcus aureus bacteremia: pearl or pellet? 
  • Vancomycin-associated linear IgA dermatosis. A report of three cases. 
  • Vancomycin-resistant enterococci: risk related to the use of intravenous vancomycin in a university hospital. 
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  Keywords of People

  • Olsen, Maren Karine, Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics