Genetic Variation

• 

  Subject Areas on Research

  • "Good enough solutions" and the genetics of complex diseases. 
  • 172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant. 
  • 2μ plasmid in Saccharomyces species and in Saccharomyces cerevisiae. 
  • 50 Years of Emmonsia Disease in Humans: The Dramatic Emergence of a Cluster of Novel Fungal Pathogens. 
  • 50 million years of genomic stasis in endosymbiotic bacteria. 
  • A Genocentric Approach to Discovery of Mendelian Disorders. 
  • A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry. 
  • A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk. 
  • A NEIL1 single nucleotide polymorphism (rs4462560) predicts the risk of radiation-induced toxicities in esophageal cancer patients treated with definitive radiotherapy. 
  • A Quantitative Analysis of Growth and Size Regulation in Manduca sexta: The Physiological Basis of Variation in Size and Age at Metamorphosis. 
  • A Recurrent De Novo Variant in NACC1 Causes a Syndrome Characterized by Infantile Epilepsy, Cataracts, and Profound Developmental Delay. 
  • A biometrical genome search in rats reveals the multigenic basis of blood pressure variation. 
  • A common variant near TGFBR3 is associated with primary open angle glaucoma. 
  • A common variant on chromosome 9p21 affects the risk of myocardial infarction. 
  • A comprehensive mutation analysis of RP2 and RPGR in a North American cohort of families with X-linked retinitis pigmentosa. 
  • A conservative test of genetic drift in the endosymbiotic bacterium Buchnera: slightly deleterious mutations in the chaperonin groEL. 
  • A copy number variation morbidity map of developmental delay. 
  • A cystic fibrosis transmembrane conductance regulator splice variant with partial penetrance associated with variable cystic fibrosis presentations. 
  • A functional polymorphism in the ATP-Binding Cassette B1 transporter predicts pharmacologic response to combination of nortriptyline and morphine in neuropathic pain patients. 
  • A functional variant (-1304T>G) in the MKK4 promoter contributes to a decreased risk of lung cancer by increasing the promoter activity. 
  • A generalized least-squares estimate for the origin of sporophytic self-incompatibility. 
  • A genome-wide analysis of putative functional and exonic variation associated with extremely high intelligence 
  • A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 
  • A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. 
  • A genome-wide association study of suicide attempts and suicidal ideation in U.S. military veterans. 
  • A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. 
  • A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease. 
  • A genome-wide investigation of SNPs and CNVs in schizophrenia. 
  • A genome-wide scan for common alleles affecting risk for autism. 
  • A genome-wide survey of copy number variations in Han Chinese residing in Taiwan. 
  • A global meta-analysis of Tuber ITS rDNA sequences: species diversity, host associations and long-distance dispersal. 
  • A global reference for human genetic variation. 
  • A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response. 
  • A longitudinal study of epigenetic variation in twins. 
  • A mechanistic study of evolvability using the mitogen-activated protein kinase cascade. 
  • A molecular phylogeny of the fern family Pteridaceae: assessing overall relationships and the affinities of previously unsampled genera 
  • A multilocus sequence survey in Arabidopsis thaliana reveals a genome-wide departure from a neutral model of DNA sequence polymorphism. 
  • A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS. 
  • A novel 2-oxoacid-dependent dioxygenase involved in the formation of the goiterogenic 2-hydroxybut-3-enyl glucosinolate and generalist insect resistance in Arabidopsis,. 
  • A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity. 
  • A novel variant marking HLA-DP expression levels predicts recovery from hepatitis B virus infection. 
  • A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469. 
  • A phylogeographically distinct and deep divergence in the widespread Neotropical turnip-tailed gecko, Thecadactylus rapicauda. 
  • A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum. 
  • A public resource facilitating clinical use of genomes. 
  • A re-evaluation of 12S ribosomal RNA variability in Drosophila pseudoobscura. 
  • A refined model of the genomic basis for phenotypic variation in vertebrate hemostasis. 
  • A regulatory variant of the human tryptophan hydroxylase-2 gene biases amygdala reactivity. 
  • A stochastic evolutionary model for protein structure alignment and phylogeny. 
  • A strong effect of AT mutational bias on amino acid usage in Buchnera is mitigated at high-expression genes. 
  • A susceptibility gene for affective disorders and the response of the human amygdala. 
  • A three-generation approach in biodemography is based on the developmental profiles and the epigenetics of female gametes. 
  • A variant of the DNA repair gene XRCC3 and risk of squamous cell carcinoma of the head and neck: a case-control analysis. 
  • APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis. 
  • APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy. 
  • APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy. 
  • Absence of mitochondrial progesterone receptor polymorphisms in women with spontaneous preterm birth. 
  • Abundance and diversity of Schizophyllum commune spore clouds in the Caribbean detected by selective sampling. 
  • Abundance and genetic diversity of aerobic anoxygenic phototrophic bacteria of coastal regions of the pacific ocean. 
  • Acute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus. 
  • Adaptive Radiation Genomics of Two Ecologically Divergent Hawai'ian Honeycreepers: The 'akiapōlā'au and the Hawai'i 'amakihi. 
  • Adaptive divergence in plasticity in natural populations of Impatiens capensis and its consequences for performance in novel habitats. 
  • Adaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs. 
  • Adding pharmacogenetics information to drug labels: lessons learned. 
  • African-American HLA class II allele and haplotype diversity. 
  • African-American HLA class II allele and haplotype diversity. 
  • Age at maturity in wild baboons: genetic, environmental and demographic influences. 
  • Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample. 
  • Aggregate Effects of Intraocular Pressure and Cup-to-Disc Ratio Genetic Variants on Glaucoma in a Multiethnic Asian Population. 
  • Allele-specific assay reveals functional variation in the chalcone synthase promoter of Arabidopsis thaliana that is compatible with neutral evolution. 
  • Allele-specific gene expression in a wild nonhuman primate population. 
  • Allelic Imbalance Is a Prevalent and Tissue-Specific Feature of the Mouse Transcriptome. 
  • Allelic and locus heterogeneity in inherited venous malformations. 
  • Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis. 
  • Allelic diversity and gene genealogy at the self-incompatibility locus in the Solanaceae. 
  • Allelic diversity in the TGFB1 regulatory region: characterization of novel functional single nucleotide polymorphisms. 
  • Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli. 
  • Allelic variation in human gene expression. 
  • Allotetraploid Mimulus sookensis are highly interfertile despite independent origins. 
  • Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants. 
  • Amino acid-level signal-to-noise analysis of incidentally identified variants in genes associated with long QT syndrome during pediatric whole exome sequencing reflects background genetic noise. 
  • Amplification of a complete simian immunodeficiency virus genome from fecal RNA of a wild chimpanzee. 
  • An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease. 
  • An Exome Sequencing Study to Assess the Role of Rare Genetic Variation in Pulmonary Fibrosis. 
  • An activated factor VII variant with enhanced tissue factor-independent activity speeds wound healing in a mouse hemophilia B model. 
  • An active site tyrosine influences the ability of the dimethyl sulfoxide reductase family of molybdopterin enzymes to reduce S-oxides. 
  • An atlas of genetic influences on human blood metabolites. 
  • An epigenetic pathway in rice connects genetic variation to anaerobic germination and seedling establishment. 
  • An integrated encyclopedia of DNA elements in the human genome. 
  • An integrated map of genetic variation from 1,092 human genomes. 
  • An introgression analysis of quantitative trait loci that contribute to a morphological difference between Drosophila simulans and D. mauritiana. 
  • Analyses of pediatric isolates of Cryptococcus neoformans from South Africa. 
  • Analysis of non-synonymous-coding variants of Parkinson's disease-related pathogenic and susceptibility genes in East Asian populations. 
  • Analysis of shared heritability in common disorders of the brain. 
  • Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins. 
  • Analysis of the protein products encoded by variant glucokinase transcripts via expression in bacteria. 
  • Analytical DNA fingerprinting in lions: parentage, genetic diversity, and kinship. 
  • Ancestral population genomics: the coalescent hidden Markov model approach. 
  • Ancient and recent positive selection transformed opioid cis-regulation in humans. 
  • Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting. 
  • Anther-stigma separation is associated with inbreeding depression in Datura stramonium, a predominantly self-fertilizing annual. 
  • Antiepileptic Drug Teratogenicity and De Novo Genetic Variation Load. 
  • Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins. 
  • Apolipoprotein E and Alzheimer's disease. 
  • Apolipoprotein L1 gene variants in deceased organ donors are associated with renal allograft failure. 
  • Assessing genetic association with human survival at multi-allelic loci. 
  • Assessing the Role of Rare Genetic Variation in Patients With Heart Failure. 
  • Assessment of genetic relatedness of vaginal isolates of Candida albicans from different geographical origins. 
  • Assessment of the genetic variance of late-onset Alzheimer's disease. 
  • Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses. 
  • Association between ICAM-1 Gly-Arg polymorphism and renal parenchymal scarring following childhood urinary tract infection. 
  • Association between chromosome 2p16.3 variants and glaucoma in populations of African descent. 
  • Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer. 
  • Association between genetic variation at the porphobilinogen deaminase gene and schizophrenia. 
  • Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye. 
  • Association of a cystatin C gene variant with cystatin C levels, CKD, and risk of incident cardiovascular disease and mortality. 
  • Association of a functional tandem repeats in the downstream of human telomerase gene and lung cancer. 
  • Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. 
  • Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. 
  • Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age. 
  • Association of genetic variants in the HDL receptor, SR-B1, with abnormal lipids in women with coronary artery disease. 
  • Association of genetic variants of FBXO32 and FOXO6 in the FOXO pathway with breast cancer risk. 
  • Association of genetic variation in IKZF1, ARID5B, and CEBPE and surrogates for early-life infections with the risk of acute lymphoblastic leukemia in Hispanic children. 
  • Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. 
  • Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. 
  • Association of misexpression with sterility in hybrids of Drosophila simulansand D. mauritiana. 
  • Association of tumor necrosis factor-alpha promoter variants with risk of HPV-associated oral squamous cell carcinoma. 
  • Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk. 
  • Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore. 
  • Association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in the Taiwanese population. 
  • Association test using Copy Number Profile Curves (CONCUR) enhances power in rare copy number variant analysis. 
  • Associations, populations, and the truth: recommendations for genetic association studies in Arthritis & Rheumatism. 
  • Autism and developmental disability caused by KCNQ3 gain-of-function variants. 
  • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. 
  • AutoCSA, an algorithm for high throughput DNA sequence variant detection in cancer genomes. 
  • BAG3 (Bcl-2-Associated Athanogene-3) Coding Variant in Mice Determines Susceptibility to Ischemic Limb Muscle Myopathy by Directing Autophagy. 
  • BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner. 
  • Balancing selection and trans-specific polymorphisms. 
  • Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans. 
  • Bcr-Abl variants: biological and clinical aspects. 
  • Better together: Thinking anthropologically about genetics. 
  • Between-site differences in the scale of dispersal and gene flow in red oak. 
  • Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. 
  • Biodemographic trajectories of longevity. 
  • Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer. 
  • Biological diversity: where is it? 
  • Biotic interactions. Genomics and coevolution. 
  • Boechera, a model system for ecological genomics. 
  • CCL3L1 and HIV/AIDS susceptibility. 
  • CD4 receptor diversity in chimpanzees protects against SIV infection. 
  • COMT gene locus: new functional variants. 
  • CYP2C19 variation and citalopram response. 
  • Calcium and calcium receptor CAS promote Arabidopsis thaliana de-etiolation. 
  • Can Genetics Predict Response to Complex Behavioral Interventions? Evidence from a Genetic Analysis of the Fast Track Randomized Control Trial 
  • Candida virulence properties and adverse clinical outcomes in neonatal candidiasis. 
  • Captivity humanizes the primate microbiome. 
  • Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice. 
  • Case-Only Survival Analysis Reveals Unique Effects of Genotype, Sex, and Coronary Disease Severity on Survivorship. 
  • Case-control association between CCT-associated variants and keratoconus in a Saudi Arabian population. 
  • Catechol O-methyltransferase haplotype predicts immediate musculoskeletal neck pain and psychological symptoms after motor vehicle collision. 
  • Causal Genetic Variants in Stillbirth. 
  • Causal effects of cardiovascular risk factors on onset of major age-related diseases: A time-to-event Mendelian randomization study. 
  • Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation. 
  • Centralized immunogens as a vaccine strategy to overcome HIV-1 diversity. 
  • Cerebral cortical gray matter overgrowth and functional variation of the serotonin transporter gene in autism. 
  • Changing the paradigm from 'race' to human genome variation. 
  • Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery. 
  • Characterization of alpha-toxin hla gene variants, alpha-toxin expression levels, and levels of antibody to alpha-toxin in hemodialysis and postsurgical patients with Staphylococcus aureus bacteremia. 
  • Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop 'G4 Kissing' interaction. 
  • Characterization of primary isolate-like variants of simian-human immunodeficiency virus. 
  • Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants. 
  • Characterization of the Transmitted Virus in an Ongoing HIV-1 Epidemic Driven by Injecting Drug Use. 
  • Child μ-opioid receptor gene variant influences parent-child relations. 
  • Chromatin and DNA replication. 
  • Chromosome 17q12 variants contribute to risk of early-onset prostate cancer. 
  • Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. 
  • Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study. 
  • Cis-regulatory evolution of chalcone-synthase expression in the genus Arabidopsis. 
  • Classifying the evolutionary and ecological features of neoplasms. 
  • Clinical interpretation and implications of whole-genome sequencing. 
  • Clonality and recombination in genetically differentiated subgroups of Cryptococcus gattii. 
  • Cloning, characterization, and expression of two angiotensin receptor (AT-1) isoforms from the mouse genome. 
  • Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity. 
  • Coalescent Theory of Migration Network Motifs. 
  • Combination of exome sequencing and immune testing confirms Aicardi-Goutières syndrome type 5 in a challenging pediatric neurology case. 
  • Combinatorial and synergistic properties of CaMV 35S enhancer subdomains. 
  • Combined effects of the p53 and p73 polymorphisms on lung cancer risk. 
  • Commentary: When does understanding phenotypic evolution require identification of the underlying genes? 
  • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk. 
  • Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. 
  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. 
  • Common genetic variants on 5p14.1 associate with autism spectrum disorders. 
  • Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. 
  • Common genetic variation and performance on standardized cognitive tests. 
  • Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study. 
  • Common genetic variation and the control of HIV-1 in humans. 
  • Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. 
  • Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants. 
  • Common human ANK2 variant confers in vivo arrhythmia phenotypes. 
  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. 
  • Common variants in Mendelian kidney disease genes and their association with renal function. 
  • Common variation in the BRCA1 gene and prostate cancer risk. 
  • Community engagement and informed consent in the International HapMap project. 
  • Comparative RNA sequencing reveals substantial genetic variation in endangered primates. 
  • Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee. 
  • Comparative analyses of clinical and environmental populations of Cryptococcus neoformans in Botswana. 
  • Comparative analysis of quantitative trait loci controlling glucosinolates, myrosinase and insect resistance in Arabidopsis thaliana. 
  • Comparative evolutionary analysis of chalcone synthase and alcohol dehydrogenase loci in Arabidopsis, Arabis, and related genera (Brassicaceae). 
  • Comparative gene genealogical analyses of strains of serotype AD identify recombination in populations of serotypes A and D in the human pathogenic yeast Cryptococcus neoformans. 
  • Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. 
  • Comparative genomics and regulatory evolution: conservation and function of the Chs and Apetala3 promoters. 
  • Comparative genomics provides new insights into the diversity, physiology, and sexuality of the only industrially exploited tremellomycete: Phaffia rhodozyma. 
  • Comparative genomics reveals insights into avian genome evolution and adaptation. 
  • Comparative genomics search for losses of long-established genes on the human lineage. 
  • Comparative hybridization reveals extensive genome variation in the AIDS-associated pathogen Cryptococcus neoformans. 
  • Comparative population structure of two deep-sea hydrothermal-vent-associated decapods (Chorocaris sp. 2 and Munidopsis lauensis) from southwestern Pacific back-arc basins. 
  • Comparative quantitative trait loci mapping of aliphatic, indolic and benzylic glucosinolate production in Arabidopsis thaliana leaves and seeds. 
  • Comparative structural analysis of HLA-A2 antigens distinguishable by cytotoxic T lymphocytes: variants M7 and DR1. 
  • Comparison of ribosomal DNA ITS regions among geographic isolates of Cenococcum geophilum. 
  • Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design. 
  • Competition in oxygen-linked anion binding to normal and variant human hemoglobins. 
  • Complement factor H variant increases the risk of age-related macular degeneration. 
  • Complete genomic screen for disease susceptibility loci in nuclear families. 
  • Complex selection on a regulator of social cognition: Evidence of balancing selection, regulatory interactions and population differentiation in the prairie vole Avpr1a locus. 
  • Complex-trait analysis in plants. 
  • Complexity of the msp2 locus and the severity of childhood malaria, in south-western Nigeria. 
  • Comprehensive analysis of ADA2 genetic variants and estimation of carrier frequency driven by a function-based approach. 
  • Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease. 
  • Computational tools for understanding sequence variability in recombination signals. 
  • Conceptualizing human variation. 
  • Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry. 
  • Connecting genetic risk to disease end points through the human blood plasma proteome. 
  • Connecting recombination, nucleotide diversity and species divergence in Drosophila. 
  • Consensus and ancestral state HIV vaccines. 
  • Consensus statement on transcultural issues in depression and anxiety from the International Consensus Group on Depression and Anxiety. 
  • Conservation and diversification of SCARECROW in maize. 
  • Conservation genomic analysis reveals ancient introgression and declining levels of genetic diversity in Madagascar's hibernating dwarf lemurs. 
  • Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant. 
  • Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant: further clarifications. 
  • Cooperation and functional diversification of two closely related galactolipase genes for jasmonate biosynthesis. 
  • Coping with viral diversity in HIV vaccine design: a response to Nickle et al. 
  • Copy number variation contributes to cryptic genetic variation in outbreak lineages of Cryptococcus gattii from the North American Pacific Northwest. 
  • Correlation between env V1/V2 region diversification and neutralizing antibodies during primary infection by simian immunodeficiency virus sm in rhesus macaques. 
  • Country Level Diversity of the HIV-1 Pandemic between 1990 and 2015. 
  • Critical weight in the development of insect body size. 
  • Cross-species microsatellite markers for elucidating population genetic structure in Arabidopsis and Arabis (Brassicaeae). 
  • Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen. 
  • Cryptic variation in butterfly eyespot development: the importance of sample size in gene expression studies 
  • Cryptococcus neoformans shows a remarkable genotypic diversity in Brazil. 
  • DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. 
  • DNA copy number evolution in Drosophila cell lines. 
  • DNA repair gene polymorphisms and risk of pancreatic cancer. 
  • DNA- and PCR-fingerprinting in fungi. 
  • DNase I sensitivity QTLs are a major determinant of human expression variation. 
  • DOG1 expression is predicted by the seed-maturation environment and contributes to geographical variation in germination in Arabidopsis thaliana. 
  • Darwinian genomics and diversity in the tree of life. 
  • De novo assembly using low-coverage short read sequence data from the rice pathogen Pseudomonas syringae pv. oryzae. 
  • De novo variants in TCF7L2 are associated with a syndromic neurodevelopmental disorder. 
  • Decoupling of genome size and sequence divergence in a symbiotic bacterium. 
  • Deep Sequencing of 71 Candidate Genes to Characterize Variation Associated with Alcohol Dependence. 
  • Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification. 
  • Deep Sequencing of Three Loci Implicated in Large-Scale Genome-Wide Association Study Smoking Meta-Analyses. 
  • Deep whole-genome sequencing of 100 southeast Asian Malays. 
  • Deficiency of Adenosine Deaminase 2 (DADA2): Hidden Variants, Reduced Penetrance, and Unusual Inheritance. 
  • Defining the role of common variation in the genomic and biological architecture of adult human height. 
  • Deleterious mutations and genetic variation for flower size in Mimulus guttatus. 
  • Density dependence and population differentiation of genetic architecture in Impatiens capensis in natural environments. 
  • Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor. 
  • Detection of allelic variations of human gene expression by polymerase colonies. 
  • Detection of diverse variants of human immunodeficiency virus-1 groups M, N, and O and simian immunodeficiency viruses from chimpanzees by using generic pol and env primer pairs. 
  • Detection of phylogenetically diverse human immunodeficiency virus type 1 groups M and O from plasma by using highly sensitive and specific generic primers. 
  • Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity. 
  • Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation. 
  • Developing a synthetic psychosocial stress measure and harmonizing CVD-risk data: a way forward to GxE meta- and mega-analyses. 
  • Developmental mediation of genetic variation in response to the Fast Track prevention program. 
  • Different evolutionary pathways of HIV-1 between fetus and mother perinatal transmission pairs indicate unique immune selection in fetuses. 
  • Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior. 
  • Diploid apomicts of the Boechera holboellii complex display large-scale chromosome substitutions and aberrant chromosomes. 
  • Direct allelic variation scanning of the yeast genome. 
  • Discordant and heterogeneous clinically relevant genomic alterations in circulating tumor cells vs plasma DNA from men with metastatic castration resistant prostate cancer. 
  • Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. 
  • Distinctive variation in the U3R region of the 5' Long Terminal Repeat from diverse HIV-1 strains. 
  • Distribution and medical impact of loss-of-function variants in the Finnish founder population. 
  • Distribution of WDR36 DNA sequence variants in patients with primary open-angle glaucoma. 
  • Distribution, ecology, life history, genetic variation, and risk of extinction of nonhuman primates from Costa Rica. 
  • Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain function. 
  • Diverse genetic causes of polymicrogyria with epilepsy. 
  • Diversification before the most recent glaciation in Balanus glandula. 
  • Diversification of phytochrome contributions to germination as a function of seed-maturation environment. 
  • Diversity and host range of foliar fungal endophytes: are tropical leaves biodiversity hotspots? 
  • Diversity and selectivity in mRNA translation on the endoplasmic reticulum. 
  • Diversity considerations in HIV-1 vaccine selection. 
  • Diversity in the realm of eukaryotic microbe form and function. 
  • Diversity of ankyrins in the brain. 
  • Diversity of full-length subtype E HIV type 1 env sequences in early seroconvertors from northern Thailand. 
  • Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program. 
  • Dramatic Response After Lamotrigine in a Patient With Epileptic Encephalopathy and a De NovoCACNA1A Variant. 
  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. 
  • Dynamics of microsatellite divergence under stepwise mutation and proportional slippage/point mutation models. 
  • Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder. 
  • EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity. 
  • Early onset prostate cancer has a significant genetic component. 
  • Early-onset of symptoms and clinical course of Pompe disease associated with the c.-32-13 T > G variant. 
  • Ecological reproductive isolation of coast and inland races of Mimulus guttatus. 
  • Education influences the association between genetic variants and refractive error: a meta-analysis of five Singapore studies. 
  • Effect of Genetic African Ancestry on eGFR and Kidney Disease. 
  • Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes. 
  • Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system. 
  • Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder. 
  • Effect of vertical sleeve gastrectomy in melanocortin receptor 4-deficient rats. 
  • Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial. 
  • Effects of selection and mutation on mitochondrial variation and inferences of historical population expansion in a Caribbean reef fish. 
  • Effects of sequence variation on differential allelic transcription factor occupancy and gene expression. 
  • Effects of variation at the flower-colour A locus on mating system parameters in Ipomoea purpurea. 
  • Efficacy of the pharmacologic chaperone migalastat in a subset of male patients with the classic phenotype of Fabry disease and migalastat-amenable variants: data from the phase 3 randomized, multicenter, double-blind clinical trial and extension study. 
  • Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone. 
  • Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal. 
  • Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells. 
  • Enlarged Dural Sac in Idiopathic Bronchiectasis Implicates Heritable Connective Tissue Gene Variants. 
  • Envelope diversity, coreceptor usage and syncytium-inducing phenotype of HIV-1 variants in saliva and blood during primary infection. 
  • Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus. 
  • Environmental and genetic influences on the germination of Arabidopsis thaliana in the field. 
  • Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC). 
  • Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. 
  • Epstein-Barr Virus Genomes Reveal Population Structure and Type 1 Association with Endemic Burkitt Lymphoma. 
  • Erythrocyte Webb-type glycophorin C variant lacks N-glycosylation due to an asparagine to serine substitution. 
  • Escape from homeostasis. 
  • Estimating the heritability of cognitive traits across dog breeds reveals highly heritable inhibitory control and communication factors. 
  • Evaluation of the Genetic Variance of Alzheimer's Disease Explained by the Disease-Associated Chromosomal Regions. 
  • Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations. 
  • Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. 
  • Evidence for substantial effect modification by gender in a large-scale genetic association study of the metabolic syndrome among coronary heart disease patients. 
  • Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. 
  • Evidence from opsin genes rejects nocturnality in ancestral primates. 
  • Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub-Saharan Africa. 
  • Evidence that methylation of the FMR-I locus is responsible for variable phenotypic expression of the fragile X syndrome. 
  • Evidence that structural variants within the human delta-globin protein may reflect genetic interactions between the delta- and beta-globin genes. 
  • Evolution and diversity in human herpes simplex virus genomes. 
  • Evolution of a polyphenism by genetic accommodation. 
  • Evolution of host range in Coleosporium ipomoeae, a plant pathogen with multiple hosts. 
  • Evolution of king crabs from hermit crab ancestors. 
  • Evolution of plant resistance at the molecular level: ecological context of species interactions. 
  • Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes. 
  • Evolution of the gene encoding mitochondrial intermediate peptidase and its cosegregation with the A mating-type locus of mushroom fungi. 
  • Evolution, interactions, and biological networks. 
  • Evolution. Chaperones as buffering agents? 
  • Evolutionary analysis of the well characterized endo16 promoter reveals substantial variation within functional sites. 
  • Evolutionary biology: significance of primate sexual swellings. 
  • Evolutionary design on a budget: robustness and optimality of bacteriophage T7. 
  • Evolutionary dissociations between homologous genes and homologous structures. 
  • Evolutionary dynamics of an Arabidopsis insect resistance quantitative trait locus. 
  • Evolutionary genetics and acclimatization in nephrology. 
  • Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. 
  • Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease. 
  • Exome sequencing identifies gene variants and networks associated with extreme respiratory outcomes following preterm birth. 
  • Exome-Based Rare-Variant Analyses in CKD. 
  • Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine. 
  • Experimental analysis of sources of error in evolutionary studies based on Roche/454 pyrosequencing of viral genomes. 
  • Experimental habitat fragmentation increases linkage disequilibrium but does not affect genetic diversity or population structure in the Amazonian liverwort Radula flaccida. 
  • Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci. 
  • Exploiting expression patterns across multiple tissues to map expression quantitative trait loci. 
  • Exploring molecular diversity with combinatorial shape libraries. 
  • Extended ORF8 Gene Region Is Valuable in the Epidemiological Investigation of Severe Acute Respiratory Syndrome-Similar Coronavirus. 
  • Extensive chloroplast haplotype variation indicates Pleistocene hybridization and radiation of North American Arabis drummondii, A. x divaricarpa, and A. holboellii (Brassicaceae). 
  • Extensive haplotype diversity in African American mothers and their cord blood units. 
  • Extensive junctional diversity of rearranged human T cell receptor delta genes. 
  • Extensive recombination due to heteroduplexes generates large amounts of artificial gene fragments during PCR. 
  • Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality. 
  • Extreme selective sweeps independently targeted the X chromosomes of the great apes. 
  • FOXP2 variation in great ape populations offers insight into the evolution of communication skills. 
  • Factors affecting harp seal (Pagophilus groenlandicus) strandings in the Northwest Atlantic. 
  • Factors associated with the diversification of the gut microbial communities within chimpanzees from Gombe National Park. 
  • Failure to replicate two mate preference QTLs across multiple strains of Drosophila pseudoobscura. 
  • Family-based association tests for rare variants with censored traits. 
  • Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1. 
  • Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity. 
  • Fine-scale crossover rate heterogeneity in Drosophila pseudoobscura. 
  • Fine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergence. 
  • Fine-scale phylogenetic architecture of a complex bacterial community. 
  • Fine-scale population genetic structure in a fission-fusion society. 
  • Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing. 
  • Flow cytometric analysis of fluorescence resonance energy transfer: a tool for high-throughput screening of molecular interactions in living cells. 
  • Flux control in a plant defense pathway is robust to environmental perturbations and controls variation in adaptive traits 
  • Formalizing morphologically cryptic biological entities: new insights from DNA taxonomy, hybridization, and biogeography in the leafy liverwort Porella platyphylla (Jungermanniopsida, Porellales). 
  • Frequent circumarctic and rare transequatorial dispersals in the lichenised agaric genus Lichenomphalia (Hygrophoraceae, Basidiomycota). 
  • From genome-wide to candidate gene: an investigation of variation at the major histocompatibility complex in common bottlenose dolphins exposed to harmful algal blooms. 
  • From genotype to phenotype: systems biology meets natural variation. 
  • From man to fish: What can Zebrafish tell us about ApoL1 nephropathy? 
  • Functional FLT1 Genetic Variation is a Prognostic Factor for Recurrence in Stage I-III Non-Small-Cell Lung Cancer. 
  • Functional Variants in Notch Pathway Genes NCOR2, NCSTN, and MAML2 Predict Survival of Patients with Cutaneous Melanoma. 
  • Functional analysis of intra-allelic variation at NACP-Rep1 in the alpha-synuclein gene. 
  • Functional analysis of novel SNPs and mutations in human and mouse genomes. 
  • Functional assessment of variants in the TSC1 and TSC2 genes identified in individuals with Tuberous Sclerosis Complex. 
  • Functional consequences of natural sequence variation in the activation domain of HIV-1 Rev. 
  • Functional divergence in tandemly duplicated Arabidopsis thaliana trypsin inhibitor genes. 
  • Functional diversity of notch family genes in fetal lung development. 
  • Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. 
  • Functional neuroimaging of genetic variation in serotonergic neurotransmission. 
  • Functional polymorphisms in the promoter regions of the FAS and FAS ligand genes and risk of bladder cancer in south China: a case-control analysis. 
  • Functional polymorphisms of matrix metalloproteinase-9 are associated with risk of occurrence and metastasis of lung cancer. 
  • Functional variants in DCAF4 associated with lung cancer risk in European populations. 
  • Fungal community analysis by large-scale sequencing of environmental samples. 
  • Fungal mating: Candida albicans flips a switch to get in the mood. 
  • Further evidence for the involvement of EFL1 in a Shwachman-Diamond-like syndrome and expansion of the phenotypic features. 
  • Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. 
  • G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers. 
  • GAA variants and phenotypes among 1,079 patients with Pompe disease: Data from the Pompe Registry. 
  • GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. 
  • GWAS or Gee Whiz, PSAS or Pshaw: elucidating the biologic and clinical significance of genetic variation in cardiovascular disease. 
  • Gene expression and adaptive noncoding changes during human evolution. 
  • Gene expression divergence and the origin of hybrid dysfunctions. 
  • General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations. 
  • Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity. 
  • Generators of phenotypic diversity in the evolution of pathogenic microorganisms. 
  • Genes and environment in neonatal intraventricular hemorrhage. 
  • Genetic Consequences of Biologically Altered Environments. 
  • Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. 
  • Genetic Influences on Plasma Homocysteine Levels in African Americans and Yoruba Nigerians. 
  • Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis. 
  • Genetic Variants Associated With Vincristine-Induced Peripheral Neuropathy in Two Populations of Children With Acute Lymphoblastic Leukemia. 
  • Genetic Variants Associated with Circulating Parathyroid Hormone. 
  • Genetic Variants Predict Optimal Timing of Radiotherapy to Reduce Side-effects in Breast Cancer Patients. 
  • Genetic Variants in WNT2B and BTRC Predict Melanoma Survival. 
  • Genetic Variants of the MDM2 Gene Are Predictive of Treatment-Related Toxicities and Overall Survival in Patients With Advanced NSCLC. 
  • Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia. 
  • Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma. 
  • Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction. 
  • Genetic analysis of the beta-tubulin gene, TUBB, in non-small-cell lung cancer. 
  • Genetic and 'cultural' similarity in wild chimpanzees. 
  • Genetic and environmental influences on functional abilities in Danish twins aged 75 years and older. 
  • Genetic and evolutionary correlates of fine-scale recombination rate variation in Drosophila persimilis. 
  • Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium. 
  • Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes. 
  • Genetic and physiological basis of adaptive salt tolerance divergence between coastal and inland Mimulus guttatus. 
  • Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing. 
  • Genetic architecture of human pain perception. 
  • Genetic association between endothelial nitric oxide synthase and Alzheimer disease. 
  • Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions. 
  • Genetic basis and consequences of niche construction: plasticity-induced genetic constraints on the evolution of seed dispersal in Arabidopsis thaliana. 
  • Genetic control of blood pressure and the angiotensinogen locus. 
  • Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent. 
  • Genetic determinants in HIV-1 Gag and Env V3 are related to viral response to combination antiretroviral therapy with a protease inhibitor. 
  • Genetic determinants of renal transplant outcome: where do we stand? 
  • Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. 
  • Genetic determinants of variable metabolism have little impact on the clinical use of leading antipsychotics in the CATIE study. 
  • Genetic dissection of interspecific differences in yeast thermotolerance. 
  • Genetic divergence causes parallel evolution of flower color in Chilean Mimulus. 
  • Genetic diversity among Mycobacterium avium complex strains recovered from children with and without human immunodeficiency virus infection. 
  • Genetic diversity does not explain variation in extra-pair paternity in multiple populations of a songbird. 
  • Genetic diversity fuels gene discovery for tobacco and alcohol use. 
  • Genetic diversity in the Mycobacterium tuberculosis complex based on variable numbers of tandem DNA repeats. 
  • Genetic diversity of coastal bottlenose dolphins revealed by structurally and functionally diverse hemoglobins. 
  • Genetic diversity of human immunodeficiency virus type 2: evidence for distinct sequence subtypes with differences in virus biology. 
  • Genetic diversity of the Cryptococcus species complex suggests that Cryptococcus gattii deserves to have varieties. 
  • Genetic diversity of the msp-1 locus and symptomatic malaria in south-west Nigeria. 
  • Genetic effects on mating success and partner choice in a social mammal. 
  • Genetic evidence and integration of various data sources for classifying uncertain variants into a single model. 
  • Genetic evidence for long-term population decline in a savannah-dwelling primate: inferences from a hierarchical bayesian model. 
  • Genetic evidence reveals temporal change in hybridization patterns in a wild baboon population. 
  • Genetic factors in susceptibility to death: a comparative analysis of bivariate survival models. 
  • Genetic heterogeneity of diffuse large B-cell lymphoma. 
  • Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes. 
  • Genetic influence of CCR5, CCR2, and SDF1 variants on human immunodeficiency virus 1 (HIV-1)-related disease progression and neurological impairment, in children with symptomatic HIV-1 infection. 
  • Genetic isolation by distance in Arabidopsis thaliana: biogeography and postglacial colonization of Europe. 
  • Genetic mechanisms and evolutionary significance of natural variation in Arabidopsis. 
  • Genetic modifier loci affecting survival and cardiac function in murine dilated cardiomyopathy. 
  • Genetic nature of individual frailty: comparison of two approaches. 
  • Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain. 
  • Genetic polymorphisms and the risk of stroke after cardiac surgery. 
  • Genetic polymorphisms modify bladder cancer recurrence and survival in a USA population-based prognostic study. 
  • Genetic polymorphisms of p21 are associated with risk of squamous cell carcinoma of the head and neck. 
  • Genetic recombination of poliovirus in a cell-free system. 
  • Genetic relationships and evolution of genotypes of yellow fever virus and other members of the yellow fever virus group within the Flavivirus genus based on the 3' noncoding region. 
  • Genetic screen of African Americans with Fuchs endothelial corneal dystrophy. 
  • Genetic structure of typical and atypical populations of Candida albicans from Africa. 
  • Genetic studies of human neuropathic pain conditions: a review. 
  • Genetic variability in beta-defensins is not associated with susceptibility to Staphylococcus aureus bacteremia. 
  • Genetic variability of Bacillus anthracis and related species. 
  • Genetic variability of the U5 and downstream sequence of major HIV-1 subtypes and circulating recombinant forms. 
  • Genetic variance and covariance for physiological traits in Lobelia: are there constraints on adaptive evolution? 
  • Genetic variance in fitness indicates rapid contemporary adaptive evolution in wild animals. 
  • Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium. 
  • Genetic variant of IRAK2 in the toll-like receptor signaling pathway and survival of non-small cell lung cancer. 
  • Genetic variant rs16430 6bp > 0bp at the microRNA-binding site in TYMS and risk of sporadic breast cancer risk in non-Hispanic white women aged ≤ 55 years. 
  • Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach. 
  • Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes. 
  • Genetic variants and disease: correlate or cause? 
  • Genetic variants associated with severe retinopathy of prematurity in extremely low birth weight infants. 
  • Genetic variants associated with vein graft stenosis after coronary artery bypass grafting. 
  • Genetic variants in 5-HTTLPR, BDNF, HTR1A, COMT, and FKBP5 and risk for treated depression after cancer diagnosis. 
  • Genetic variants in ERCC1 and XPC predict survival outcome of non-small cell lung cancer patients treated with platinum-based therapy. 
  • Genetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated with melanoma-specific survival. 
  • Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival. 
  • Genetic variants in SLC9A9 are associated with measures of attention-deficit/hyperactivity disorder symptoms in families. 
  • Genetic variants in TNF-α promoter are predictors of recurrence in patients with squamous cell carcinoma of oropharynx after definitive radiotherapy. 
  • Genetic variants in fanconi anemia pathway genes BRCA2 and FANCA predict melanoma survival. 
  • Genetic variants in microRNA-binding sites of DNA repair genes as predictors of recurrence in patients with squamous cell carcinoma of the oropharynx. 
  • Genetic variants in nucleotide excision repair pathway predict survival of esophageal squamous cell cancer patients receiving platinum-based chemotherapy. 
  • Genetic variants in peroxisome proliferator-activated receptor-gamma gene are associated with risk of lung cancer in a Chinese population. 
  • Genetic variants in the H2AFX promoter region are associated with risk of sporadic breast cancer in non-Hispanic white women aged  
  • Genetic variants in the MDM2 promoter and lung cancer risk in a Chinese population. 
  • Genetic variants in the PIWI-piRNA pathway gene DCP1A predict melanoma disease-specific survival. 
  • Genetic variants in the TEP1 gene are associated with prostate cancer risk and recurrence. 
  • Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk. 
  • Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium. 
  • Genetic variants near PDGFRA are associated with corneal curvature in Australians. 
  • Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. 
  • Genetic variants of JNK and p38α pathways and risk of non-small cell lung cancer in an Eastern Chinese population. 
  • Genetic variants of SDCCAG8 and MAGI2 in mitosis-related pathway genes are independent predictors of cutaneous melanoma-specific survival. 
  • Genetic variants of genes in the NER pathway associated with risk of breast cancer: A large-scale analysis of 14 published GWAS datasets in the DRIVE study. 
  • Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic Whites: a case-control study. 
  • Genetic variants of the ADPRT, XRCC1 and APE1 genes and risk of cutaneous melanoma. 
  • Genetic variants of the vitamin D receptor gene alter risk of cutaneous melanoma. 
  • Genetic variation across the human olfactory receptor repertoire alters odor perception. 
  • Genetic variation at MHC class II loci influences both olfactory signals and scent discrimination in ring-tailed lemurs. 
  • Genetic variation at a single locus and age of onset for Alzheimer's disease. 
  • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. 
  • Genetic variation in MAOA modulates ventromedial prefrontal circuitry mediating individual differences in human personality. 
  • Genetic variation in SP-A2 leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses. 
  • Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium. 
  • Genetic variation in a human odorant receptor alters odour perception. 
  • Genetic variation in adiponectin (ADIPOQ) and the type 1 receptor (ADIPOR1), obesity and prostate cancer in African Americans. 
  • Genetic variation in aldosterone synthase predicts plasma glucose levels. 
  • Genetic variation in components of dopamine neurotransmission impacts ventral striatal reactivity associated with impulsivity. 
  • Genetic variation in dopamine neurotransmission and motor development of infants born extremely-low-birthweight. 
  • Genetic variation in horizontally transmitted fungal endophytes of pine needles reveals population structure in cryptic species. 
  • Genetic variation in human NPY expression affects stress response and emotion. 
  • Genetic variation in surfactant protein-A2 alters responses to ozone. 
  • Genetic variation in the 3' non-coding region of dengue viruses. 
  • Genetic variation in the leptin receptor gene and obesity in survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. 
  • Genetic variation in the odorant receptor OR2J3 is associated with the ability to detect the "grassy" smelling odor, cis-3-hexen-1-ol. 
  • Genetic variation in the one-carbon transfer pathway and ovarian cancer risk. 
  • Genetic variation in the spread of Drosophila subobscura from a nonequilibrium population. 
  • Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. 
  • Genetic variation of DNA methyltransferase-3A contributes to protection against persistent MRSA bacteremia in patients. 
  • Genetic variation of HIV type 1 in four World Health Organization-sponsored vaccine evaluation sites: generation of functional envelope (glycoprotein 160) clones representative of sequence subtypes A, B, C, and E. WHO Network for HIV Isolation and Characterization. 
  • Genetic variation of an odorant receptor OR7D4 and sensory perception of cooked meat containing androstenone. 
  • Genetic variation within and among populations of the threatened lichen Lobaria pulmonaria in Switzerland and implications for its conservation. 
  • Genetic variations in TERT-CLPTM1L genes and risk of squamous cell carcinoma of the head and neck. 
  • Genetic variations of the ADIPOQgene and risk of prostate cancer in Chinese Han men. 
  • Genetic-based dosing in orthopedic patients beginning warfarin therapy. 
  • Genetically determined height and coronary artery disease. 
  • Genetically divergent strains of human immunodeficiency virus type 2 use multiple coreceptors for viral entry. 
  • Genetics of dispersal. 
  • Genetics of drought adaptation in Arabidopsis thaliana: I. Pleiotropy contributes to genetic correlations among ecological traits. 
  • Genetics of emotional regulation: the role of the serotonin transporter in neural function. 
  • Genetics of incipient speciation in Drosophila mojavensis. I. Male courtship song, mating success, and genotype x environment interactions. 
  • Genetics of incipient speciation in Drosophila mojavensis. III. Life-history divergence in allopatry and reproductive isolation. 
  • Genetics. FDA races in wrong direction. 
  • Genic intolerance to functional variation and the interpretation of personal genomes. 
  • Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii. 
  • Genome diversity in Brachypodium distachyon: deep sequencing of highly diverse inbred lines. 
  • Genome organization and three kinds of heritable changes: general description and stochastic factors (a review). 
  • Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects. 
  • Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts. 
  • Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. 
  • Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus. 
  • Genome-wide association analysis of clinical vs. nonclinical origin provides insights into Saccharomyces cerevisiae pathogenesis. 
  • Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians. 
  • Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease. 
  • Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. 
  • Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32. 
  • Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. 
  • Genome-wide meta-analyses of smoking behaviors in African Americans. 
  • Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. 
  • Genome-wide scan of copy number variation in late-onset Alzheimer's disease. 
  • Genomes and gene expression across light and productivity gradients in eastern subtropical Pacific microbial communities. 
  • Genomewide ancestry and divergence patterns from low-coverage sequencing data reveal a complex history of admixture in wild baboons. 
  • Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure. 
  • Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates. 
  • Genomic approaches for understanding the genetics of complex disease. 
  • Genomic features that predict allelic imbalance in humans suggest patterns of constraint on gene expression variation. 
  • Genomic impacts of chromosomal inversions in parapatric Drosophila species. 
  • Genomic medicine: genetic variation and its impact on the future of health care. 
  • Genomic profiling to promote a healthy lifestyle: not ready for prime time. 
  • Genomic risk profiling: attitudes and use in personal and clinical care of primary care physicians who offer risk profiling. 
  • Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species. 
  • Genomics and hypertension: concepts, potentials, and opportunities. 
  • Genomics: Lessons in complexity from yeast. 
  • Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice. 
  • Genotypic and Phenotypic Diversity among Human Isolates of Akkermansia muciniphila. 
  • Genotypic diversity and clinical outcome of cryptococcosis in renal transplant recipients in Brazil. 
  • Genotypic diversity of anaerobic isolates from bloodstream infections. 
  • Genotypic diversity within a natural coastal bacterioplankton population. 
  • Geographic and evolutionary diversification of glucosinolates among near relatives of Arabidopsis thaliana (Brassicaceae). 
  • Geographic patterns of microsatellite variation in Boechera stricta, a close relative of Arabidopsis. 
  • Geographic variation in algal partners of Cladonia subtenuis (Cladoniaceae) highlights the dynamic nature of a lichen symbiosis. 
  • Global Survey of Variation in a Human Olfactory Receptor Gene Reveals Signatures of Non-Neutral Evolution. 
  • Global and gene-specific DNA methylation across multiple tissues in early infancy: implications for children's health research. 
  • Global and regional epidemiology of HIV-1 recombinants in 1990-2015: a systematic review and global survey. 
  • Global and regional molecular epidemiology of HIV-1, 1990-2015: a systematic review, global survey, and trend analysis. 
  • Global distribution, diversity hot spots and niche transitions of an astaxanthin-producing eukaryotic microbe. 
  • Global patterns in peatmoss biodiversity. 
  • Glucose metabolism gene variants modulate the risk of pancreatic cancer. 
  • Gnao1 (G alphaO protein) is a likely genetic contributor to variation in physical dependence on opioids in mice. 
  • Great ape genetic diversity and population history. 
  • Growth of nutritionally variant streptococci on common laboratory and 10 commercial blood culture media. 
  • HBV whole-genome mutation profile in HIV-1/HBV coinfected patients in a long-term follow-up study. 
  • HER2 testing in metastatic colorectal cancer: ready for prime time? 
  • HIV quasispecies and resampling. 
  • HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees. 
  • HLA class I allelic diversity and progression of fibrosis in patients with chronic hepatitis C. 
  • HLA-DQA1 and APOL1 as Risk Loci for Childhood-Onset Steroid-Sensitive and Steroid-Resistant Nephrotic Syndrome. 
  • Half of the variation in susceptibility to mortality is genetic: findings from Swedish twin survival data. 
  • Haplotype of signal transducer and activator of transcription 3 gene predicts cardiovascular disease in dialysis patients. 
  • Haplotypes spanning the complement factor H gene are protective against age-related macular degeneration. 
  • Hb Catonsville (glutamic acid inserted between Pro-37(C2)alpha and Thr-38(C3)alpha). Nonallelic gene conversion in the globin system? 
  • Heritability estimates of endophenotypes of long and health life: the Long Life Family Study. 
  • Heritable individual-specific and allele-specific chromatin signatures in humans. 
  • Heritable resistance to tyrosine kinase inhibitors. 
  • Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition. 
  • Heteroplasmic mitochondrial DNA mutations in normal and tumour cells. 
  • High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men. 
  • High genetic diversity in a remote island population system: sans sex. 
  • High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. 
  • High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. 
  • High-frequency actionable pathogenic exome variants in an average-risk cohort. 
  • High-resolution deep sequencing reveals biodiversity, population structure, and persistence of HIV-1 quasispecies within host ecosystems. 
  • Historical effects on beta diversity and community assembly in Amazonian trees. 
  • History and evolution of alpine plants endemic to the Qinghai-Tibetan Plateau: Aconitum gymnandrum (Ranunculaceae). 
  • Homeostasis and dynamic stability of the phenotype link robustness and plasticity. 
  • Honest olfactory ornamentation in a female-dominant primate. 
  • Hormonal characteristics of free-ranging female lions (Panthera leo) of the Serengeti Plains and Ngorongoro Crater. 
  • Host Genetic Variant in CXCL16 May Be Associated With Hepatitis B Virus-Related Acute Liver Failure. 
  • Host genetic variation in susceptibility to Punta Toro virus. 
  • Host lifestyle affects human microbiota on daily timescales. 
  • Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice. 
  • How hot are drosophila hotspots? examining recombination rate variation and associations with nucleotide diversity, divergence, and maternal age in Drosophila pseudoobscura. 
  • Human B cell alloantigens; alpha subunit variability. 
  • Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants. 
  • Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic-cholinergic function. 
  • Human genetic admixture through the lens of population genomics. 
  • Human genetic admixture. 
  • Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia. 
  • Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol. 
  • Human histocompatibility antigen mutants immunoselected in vitro. Biochemical analysis of a mutant which synthesizes an altered HLA-A2 heavy chain. 
  • Human infection by genetically diverse SIVSM-related HIV-2 in west Africa. 
  • Human pain genetics database: a resource dedicated to human pain genetics research. 
  • Hybrid origin of SIV in chimpanzees. 
  • Hypertension Susceptibility Loci are Associated with Anthracycline-related Cardiotoxicity in Long-term Childhood Cancer Survivors. 
  • Hypothalamic-pituitary-adrenal axis genetic variation and early stress moderates amygdala function. 
  • ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. 
  • Ice-age survival of Atlantic cod: agreement between palaeoecology models and genetics. 
  • Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A. 
  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. 
  • Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. 
  • Identification and utilization of arbitrary correlations in models of recombination signal sequences. 
  • Identification of ENV determinants in V3 that influence the molecular anatomy of CCR5 utilization. 
  • Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine. 
  • Identification of a new variant of PDE1A calmodulin-stimulated cyclic nucleotide phosphodiesterase expressed in mouse sperm. 
  • Identification of a novel risk variant in the FUS gene in essential tremor. 
  • Identification of a region of genetic variability among Bacillus anthracis strains and related species. 
  • Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice. 
  • Identification of asteroid genera with species capable of larval cloning. 
  • Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma. 
  • Identification of novel mutations and sequence variants in the SOX2 and CHX10 genes in patients with anophthalmia/microphthalmia. 
  • Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals. 
  • Identification of variants in CNGA3 as cause for achromatopsia by exome sequencing of a single patient. 
  • Identifying susceptibility genes for prostate cancer--a family-based association study of polymorphisms in CYP17, CYP19, CYP11A1, and LH-beta. 
  • Idiopathic pain disorders--pathways of vulnerability. 
  • IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis. 
  • Imaging genetics and the neurobiological basis of individual differences in vulnerability to addiction. 
  • Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing. 
  • Impact of BDNF Val66Met and 5-HTTLPR polymorphism variants on neural substrates related to sadness and executive function. 
  • Impact of Bacterial and Human Genetic Variation on Staphylococcus aureus Infections. 
  • Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program. 
  • Impact of ancestry and common genetic variants on QT interval in African Americans. 
  • Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. 
  • Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls. 
  • Implementing a cumulative supermatrix approach for a comprehensive phylogenetic study of the Teloschistales (Pezizomycotina, Ascomycota). 
  • Implementing genome-driven personalized cardiology in clinical practice. 
  • In vitro kinetics of immunoglobulin synthesis and secretion by nonsecretory human myeloma cells. 
  • In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress. 
  • In vivo genetic variability of the human immunodeficiency virus type 2 V3 region. 
  • Incidentally identified genetic variants in arrhythmogenic right ventricular cardiomyopathy-associated genes among children undergoing exome sequencing reflect healthy population variation. 
  • Incongruence between genetic and morphological diversity in Microcebus griseorufus of Beza Mahafaly. 
  • Incorporating external information to improve sparse signal detection in rare-variant gene-set-based analyses. 
  • Increased risk of low birth weight in women with placental malaria associated with P. falciparum VAR2CSA clade. 
  • Independent variation and positive selection in env V1 and V2 domains within maternal-infant strains of human immunodeficiency virus type 1 in vivo. 
  • Individual variation in inbreeding depression: the roles of inbreeding history and mutation. 
  • Individualized therapy for hepatitis C infection: focus on the interleukin-28B polymorphism in directing therapy. 
  • Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma. 
  • Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity. 
  • Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability. 
  • Influence of interleukin-28B single-nucleotide polymorphisms on progression to liver cirrhosis in human immunodeficiency virus-hepatitis C virus-coinfected patients receiving antiretroviral therapy. 
  • Influence of nociception and stress-induced antinociception on genetic variation in isoflurane anesthetic potency among mouse strains. 
  • Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration. 
  • Initial sequencing and comparative analysis of the mouse genome. 
  • Insect sodium channels and insecticide resistance. 
  • Insight into the phenotype of infants with Pompe disease identified by newborn screening with the common c.-32-13T>G "late-onset" GAA variant. 
  • Integrating ethics and science in the International HapMap Project. 
  • Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility. 
  • Integrative annotation of variants from 1092 humans: application to cancer genomics. 
  • Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study. 
  • Intergenic and genic sequence lengths have opposite relationships with respect to gene expression. 
  • Interindividual variation in serum sodium and longitudinal blood pressure tracking in the Framingham Heart Study. 
  • Interleukin 12B (IL12B) genetic variation and pulmonary tuberculosis: a study of cohorts from The Gambia, Guinea-Bissau, United States and Argentina. 
  • Interleukin-10 promoter variants predict HPV-positive tumors and survival of squamous cell carcinoma of the oropharynx. 
  • Interpreting Incidentally Identified Variants in Genes Associated With Catecholaminergic Polymorphic Ventricular Tachycardia in a Large Cohort of Clinical Whole-Exome Genetic Test Referrals. 
  • Intraspecific Genetic Variation for Behavioral Isolation Loci in Drosophila. 
  • Intraspecific variation in symbiont genomes: bottlenecks and the aphid-buchnera association. 
  • Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor. 
  • Investigating Conservation of the Cell-Cycle-Regulated Transcriptional Program in the Fungal Pathogen, Cryptococcus neoformans. 
  • Is epigenetic inheritance a counterexample to the central dogma? 
  • Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults. 
  • Is the aneuploid chromosome in an apomictic Boechera holboellii a genuine B chromosome? 
  • Is there a dose-dependent effect of genetic susceptibility loci for gastric cancer on prognosis of the patients? 
  • Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder. 
  • Joint influence of small-effect genetic variants on human longevity. 
  • KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS) cohorts. 
  • Kidney Disease-Associated APOL1 Variants Have Dose-Dependent, Dominant Toxic Gain-of-Function. 
  • Lack of association of mutations in optineurin with disease in patients with adult-onset primary open-angle glaucoma. 
  • Lack of genetic differentiation between two geographically diverse samples of Candida albicans isolated from patients infected with human immunodeficiency virus. 
  • Lack of variation in voltage-gated sodium channels of common bottlenose dolphins (Tursiops truncatus) exposed to neurotoxic algal blooms. 
  • Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome. 
  • Large-scale gene-centric analysis identifies novel variants for coronary artery disease. 
  • Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD. 
  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 
  • Large-scale identification and analysis of genome-wide single-nucleotide polymorphisms for mapping in Arabidopsis thaliana. 
  • Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. 
  • Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group. 
  • Leaf-level gas-exchange uniformity and photosynthetic capacity among loblolly pine (Pinus taeda L.) genotypes of contrasting inherent genetic variation. 
  • Letter by Gurbel et al regarding article, "Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement". 
  • Letting the gene out of the bottle: OPRM1 interactions. 
  • Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium. 
  • Leveraging population information in family-based rare variant association analyses of quantitative traits. 
  • Lewy body pathology is a frequent co-pathology in familial Alzheimer's disease. 
  • Life, diversity and the pursuit of haplotypes. 
  • Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosis. 
  • Linkage of the MHC to familial multiple sclerosis suggests genetic heterogeneity. The Multiple Sclerosis Genetics Group. 
  • Local-scale genetic structure in the peatmoss Sphagnum fuscum. 
  • Long-distance dispersal and genetic structure of natural populations: an assessment of the inverse isolation hypothesis in peat mosses. 
  • Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants. 
  • Low genetic variation and no detectable population structure in aspergillus fumigatus compared to closely related Neosartorya species. 
  • Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. 
  • Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. 
  • Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases. 
  • MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome. 
  • MCP1 SNPs and pulmonary tuberculosis in cohorts from West Africa, the USA and Argentina: lack of association or epistasis with IL12B polymorphisms. 
  • Macroecological patterns of genetic structure and diversity in the aquatic moss Platyhypnidium riparioides. 
  • Maintenance Poly (ADP-ribose) Polymerase Inhibitor Therapy for Ovarian Cancer: Precision Oncology or One Size Fits All? 
  • Major flowering time gene, flowering locus C, regulates seed germination in Arabidopsis thaliana. 
  • Major histocompatibility complex variation and evolution at a single, expressed DQA locus in two genera of elephants. 
  • Major-gene resistance to the rust pathogen Coleosporium ipomoeae is common in natural populations of Ipomoea purpurea. 
  • Many globally isolated AD hybrid strains of Cryptococcus neoformans originated in Africa. 
  • Mapping and characterization of structural variation in 17,795 human genomes. 
  • Mapping autism risk loci using genetic linkage and chromosomal rearrangements. 
  • Mapping the proteo-genomic convergence of human diseases. 
  • Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort. 
  • Massively parallel sequencing of patients with intellectual disability, congenital anomalies and/or autism spectrum disorders with a targeted gene panel. 
  • Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants. 
  • Matroshka and ectopic polymorphisms: Two new classes of DNA sequence variation identified at the Van der Woude syndrome locus on 1q32-q41. 
  • Maximum-likelihood estimation of rates of recombination within mating-type regions. 
  • Medical genomics: Gather and use genetic data in health care. 
  • Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans. 
  • Membranomyces species are common ectomycorrhizal symbionts in Northern Hemisphere forests 
  • Mendelian randomisation study of the relationship between vitamin D and risk of glioma. 
  • Mendelian randomization provides support for obesity as a risk factor for meningioma. 
  • Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. 
  • Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. 
  • Meta-analysis of cardiomyopathy-associated variants in troponin genes identifies loci and intragenic hot spots that are associated with worse clinical outcomes. 
  • Meta-analysis of loci associated with age at natural menopause in African-American women. 
  • Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by human CYP1B1 genetic variants. 
  • Metagenomic and small-subunit rRNA analyses reveal the genetic diversity of bacteria, archaea, fungi, and viruses in soil. 
  • Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research. 
  • Metronidazole Metabolism in Neonates and the Interplay Between Ontogeny and Genetic Variation. 
  • MicroRNA regulation and interspecific variation of gene expression. 
  • Microgeographic patterns of genetic divergence and adaptation across natural environments in Boechera stricta (Brassicaceae) 
  • Microsatellite analysis of genetic diversity among clinical and nonclinical Saccharomyces cerevisiae isolates suggests heterozygote advantage in clinical environments. 
  • Microsatellite variation in populations of Drosophila pseudoobscura and Drosophila persimilis. 
  • Mismatched dsRNA (ampligen) induces protection against genomic variants of the human immunodeficiency virus type 1 (HIV-1) in a multiplicity of target cells. 
  • Missing genetic risk in neural tube defects: can exome sequencing yield an insight? 
  • Mistaken Identity: Another Bias in the Use of Relative Genetic Divergence Measures for Detecting Interspecies Introgression. 
  • Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans. 
  • Mitochondrial DNA variation in human metabolic rate and energy expenditure. 
  • Modeling Diversity: Do Homogeneous Laboratory Strains Limit Discovery? 
  • Modeling the influence of genetic and environmental variation on the expression of plant life cycles across landscapes. 
  • Molecular basis of defective anion transport in L cells expressing recombinant forms of CFTR. 
  • Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins. 
  • Molecular evolution of a Drosophila homolog of human BRCA2. 
  • Molecular evolutionary dynamics of cytochrome b in strepsirrhine primates: the phylogenetic significance of third-position transversions. 
  • Molecular genetics of AMD and current animal models. 
  • Molecular genetics of successful smoking cessation: convergent genome-wide association study results. 
  • Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination. 
  • Molecular phylogeny of the kinesin family of microtubule motor proteins. 
  • Molecular phylogeny, biogeography and speciation of the mushroom species Pleurotus cystidiosus and allied taxa. 
  • Molecular phylogeography and cryptic speciation in the mosses, Mielichhoferia elongata and M. mielichhoferiana (Bryaceae). 
  • Molecular signatures of selection on reproductive character displacement of flower color in Phlox drummondii. 
  • Molecular surveillance for drug-resistant Plasmodium falciparum in clinical and subclinical populations from three border regions of Burma/Myanmar: cross-sectional data and a systematic review of resistance studies. 
  • Monoclonal antibodies to malignant human gliomas. 
  • Montagnard ethnicity and genetic relations in northern Cameroon: comment on "The Peopling of Sub-Saharan Africa: The Case Study of Cameroon," by G. Spedini et al. 
  • Morphological and genetic differentiation and reproductive isolation among closely related taxa in the Ipomoea series Batatas. 
  • Morphological and molecular characterization of variation in common bean (Phaseolus vulgaris L.) germplasm from Azad Jammu and Kashmir, Pakistan. 
  • Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia. 
  • Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study. 
  • Multilocus analysis of variation and speciation in the closely related species Arabidopsis halleri and A. lyrata. 
  • Multilocus coalescent analyses reveal the demographic history and speciation patterns of mouse lemur sister species. 
  • Multilocus patterns of nucleotide diversity, population structure and linkage disequilibrium in Boechera stricta, a wild relative of Arabidopsis. 
  • Multilocus phylogenetic and geospatial analyses illuminate diversification patterns and the biogeographic history of Malagasy endemic plated lizards (Gerrhosauridae: Zonosaurinae). 
  • Multilocus sequence typing of serially collected isolates of Cryptococcus from HIV-infected patients in South Africa. 
  • Multilocus sequence typing suggests the chytrid pathogen of amphibians is a recently emerged clone. 
  • Multiple Functional Variants in cis Modulate PDYN Expression. 
  • Multiple gene genealogies reveal recent dispersion and hybridization in the human pathogenic fungus Cryptococcus neoformans. 
  • Multiple origins of hybrid strains of Cryptococcus neoformans with serotype AD. 
  • Multiple paternity and sporophytic inbreeding depression in a dioicous moss species. 
  • Multiple paths to similar germination behavior in Arabidopsis thaliana. 
  • Multiple regions within 8q24 independently affect risk for prostate cancer. 
  • Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence. 
  • Muscle trade-offs in a power-amplified prey capture system. 
  • Mutation and evolution of microsatellites in Drosophila melanogaster. 
  • Mutation screening of patients with Leber Congenital Amaurosis or the enhanced S-Cone Syndrome reveals a lack of sequence variations in the NRL gene. 
  • Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients. 
  • Mutational origin of new mating type specificities in flowering plants. 
  • Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review. 
  • Mutations that confer resistance to broadly-neutralizing antibodies define HIV-1 variants of transmitting mothers from that of non-transmitting mothers. 
  • Myocilin and optineurin coding variants in Hispanics of Mexican descent with POAG. 
  • Nager acrofacial dysostosis. 
  • Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume. 
  • Natural positive selection and north-south genetic diversity in East Asia. 
  • Natural selection on a leaf-shape polymorphism in the ivyleaf morning glory (Ipomoea hederacea). 
  • Natural selection on extrafloral nectar production in Chamaecrista fasciculata: the costs and benefits of a mutualism trait. 
  • Natural variation in CDC28 underlies morphological phenotypes in an environmental yeast isolate. 
  • Natural variation in HIV-1 protease, Gag p7 and p6, and protease cleavage sites within gag/pol polyproteins: amino acid substitutions in the absence of protease inhibitors in mothers and children infected by human immunodeficiency virus type 1. 
  • Natural variation in MAM within and between populations of Arabidopsis lyrata determines glucosinolate phenotype. 
  • Natural variation in germination responses of Arabidopsis to seasonal cues and their associated physiological mechanisms. 
  • Natural variation, differentiation, and genetic trade-offs of ecophysiological traits in response to water limitation in Brachypodium distachyon and its descendent allotetraploid B. hybridum (Poaceae). 
  • Near-Absent Levels Of Segregational Variation Suggest Limited Opportunities For The introduction of genetic variation via homeologous chromosome pairing In synthetic neoallotetraploid Mimulus. 
  • Nearshore fish (Pholis gunnellus) persists across the North Atlantic through multiple glacial episodes. 
  • Neutral evolution of the nonbinding region of the anthocyanin regulatory gene Ipmyb1 in Ipomoea. 
  • Neutralizing antibodies in sera from macaques infected with chimeric simian-human immunodeficiency virus containing the envelope glycoproteins of either a laboratory-adapted variant or a primary isolate of human immunodeficiency virus type 1. 
  • New nitrogen-fixing microorganisms detected in oligotrophic oceans by amplification of Nitrogenase (nifH) genes. 
  • Niche partitioning and biogeography of high light adapted Prochlorococcus across taxonomic ranks in the North Pacific. 
  • No Evidence That Genetic Variation in the Myeloid-Derived Suppressor Cell Pathway Influences Ovarian Cancer Survival. 
  • No evidence for linkage of liability to autism to HOXA1 in a sample from the CPEA network. 
  • No evidence of association of heterozygous NTF4 mutations in patients with primary open-angle glaucoma. 
  • Novel DNA sequence variations of cytochrome P450 genes in the Han Chinese population. 
  • Novel Genetic Triggers and Genotype-Phenotype Correlations in Patients With Left Ventricular Noncompaction. 
  • Novel splicing, missense, and deletion mutations in seven adenosine deaminase-deficient patients with late/delayed onset of combined immunodeficiency disease. Contribution of genotype to phenotype. 
  • Nuclear ribosomal DNA sequence variation and evolution of spotted marsh-orchids (Dactylorhiza maculata group) 
  • Nucleotide variation at the myrosinase-encoding locus, TGG1, and quantitative myrosinase enzyme activity variation in Arabidopsis thaliana. 
  • OPRM1 SNP (A118G): involvement in disease development, treatment response, and animal models. 
  • Oceanic islands are not sinks of biodiversity in spore-producing plants. 
  • Of cardiovascular illness and diversity of biological response. 
  • Olfactory Receptor Subgenomes Linked with Broad Ecological Adaptations in Sauropsida. 
  • On the evolution of genetic incompatibility systems. III. Introduction of weak gametophytic self-incompatibility under partial inbreeding. 
  • One haploid parent contributes 100% of the gene pool for a widespread species in northwest North America. 
  • Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing. 
  • Origin, fate, and architecture of ecologically relevant genetic variation. 
  • Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics. 
  • Outbreak of Invasive Wound Mucormycosis in a Burn Unit Due to Multiple Strains of Mucor circinelloides f. circinelloides Resolved by Whole-Genome Sequencing. 
  • Oxidative stress survival in a clinical Saccharomyces cerevisiae isolate is influenced by a major quantitative trait nucleotide. 
  • PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites. 
  • Parallel evolution of drug resistance in HIV: failure of nonsynonymous/synonymous substitution rate ratio to detect selection. 
  • Paraoxonase 1 (PON1) gene variants are not associated with clopidogrel response. 
  • Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome. 
  • Patterns and mechanisms of genetic and phenotypic differentiation in marine microbes. 
  • Patterns of evolutionary rate variation among genes of the anthocyanin biosynthetic pathway. 
  • Patterns of mandibular variation in Pan and Gorilla and implications for African ape taxonomy. 
  • Patterns of nucleotide diversity in two species of Mimulus are affected by mating system and asymmetric introgression. 
  • Patterns of nucleotide variation and reproductive isolation between a Mimulus allotetraploid and its progenitor species. 
  • Patterns of transcriptional parallelism and variation in the developing olfactory system of Drosophila species. 
  • Patterns of variation within self-incompatibility loci. 
  • Persistence of multiple maternal genotypes of human immunodeficiency virus type I in infants infected by vertical transmission. 
  • Persistent tetrodotoxin-sensitive sodium current resulting from U-to-C RNA editing of an insect sodium channel. 
  • Personalized medicine and human genetic diversity. 
  • Pharmacogenetic testing: not as simple as it seems. 
  • Pharmacogenetics: Ethical Issues and Policy Options 
  • Pharmacogenomics and end-organ susceptibility to injury in the perioperative period. 
  • Pharmacogenomics in cancer therapy: is host genome variability important? 
  • Pharmacogenomics of adverse drug reactions: implementing personalized medicine. 
  • PhenoDis: a comprehensive database for phenotypic characterization of rare cardiac diseases. 
  • Phenome-Wide Association Study of Severe COVID-19 Genetic Risk Variants. 
  • Phenotype analysis of patients with the risk variant LOC387715 (A69S) in age-related macular degeneration. 
  • Phenotypic Variability Correlates with Clinical Outcome in Cryptococcus Isolates Obtained from Botswanan HIV/AIDS Patients. 
  • Phylogenetic diversity of 200+ isolates of the ectomycorrhizal fungus Cenococcum geophilum associated with Populus trichocarpa soils in the Pacific Northwest, USA and comparison to globally distributed representatives. 
  • Phylogenetic relationships in the mushroom genus Coprinus and dark-spored allies based on sequence data from the nuclear gene coding for the large ribosomal subunit RNA: divergent domains, outgroups, and monophyly. 
  • Phylogenetic relationships of agaric fungi based on nuclear large subunit ribosomal DNA sequences. 
  • Phylogenetic relationships, morphological incongruence, and geographic speciation in the fontinalaceae (Bryophyta). 
  • Phylogenomic inferences from reference-mapped and de novo assembled short-read sequence data using RADseq sequencing of California white oaks (Quercus section Quercus). 
  • Phylogeny and biogeography of the American live oaks (Quercus subsection Virentes): a genomic and population genetics approach. 
  • Phylogeographic structure and cryptic speciation in the trans-Antarctic moss Pyrrhobryum mnioides. 
  • Phylogeography of a Morphologically Cryptic Golden Mole Assemblage from South-Eastern Africa. 
  • Phylogeography of the Solanaceae-infecting Basidiomycota fungus Rhizoctonia solani AG-3 based on sequence analysis of two nuclear DNA loci. 
  • Phylogeography of the arid-adapted Malagasy bullfrog, Laliostoma labrosum, influenced by past connectivity and habitat stability. 
  • Phytochrome diversity in green plants and the origin of canonical plant phytochromes 
  • Pioneering paradigms and magnificent manifestos--Leigh Van Valen's priceless contributions to evolutionary biology. 
  • Plasmodium falciparum Genetic Diversity in Coincident Human and Mosquito Hosts. 
  • Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. 
  • Pleiotropy in developmental regulation by flowering-pathway genes: is it an evolutionary constraint? 
  • Pneumococcal Colonization and the Nasopharyngeal Microbiota of Children in Botswana. 
  • Pollen limitation and natural selection on floral characters in the yellow monkeyflower, Mimulus guttatus. 
  • Pollinator-mediated selection on flower color allele drives reinforcement. 
  • Polygenic risk, rapid childhood growth, and the development of obesity: evidence from a 4-decade longitudinal study. 
  • Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. 
  • Polymerase chain reaction fingerprinting in fungi using single primers specific to minisatellites and simple repetitive DNA sequences: strain variation in Cryptococcus neoformans. 
  • Polymorphic TP53BP1 and TP53 gene interactions associated with risk of squamous cell carcinoma of the head and neck. 
  • Polymorphism at the ribosomal DNA spacers and its relation to breeding structure of the widespread mushroom Schizophyllum commune. 
  • Polymorphism of angiotensin converting enzyme gene is associated with circulating levels of plasminogen activator inhibitor-1. 
  • Polymorphisms in transforming growth factor-beta-related genes ALK1 and ENG are associated with sporadic brain arteriovenous malformations. 
  • Polymorphisms of DNA repair gene XRCC3 Thr241Met and risk of gastric cancer in a Chinese population. 
  • Polymorphisms of p21 and p27 jointly contribute to an earlier age at diagnosis of pancreatic cancer. 
  • Polymorphisms of the FAS and FAS ligand genes associated with risk of cutaneous malignant melanoma. 
  • Polymorphisms of thymidylate synthase in the 5'- and 3'-untranslated regions associated with risk of gastric cancer in South China: a case-control analysis. 
  • Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. 
  • Population differentiation and plasticity in vegetative ontogeny: effects on life-history expression in Erysimum capitatum (Brassicaceae). 
  • Population genetic analyses reveal the African origin and strain variation of Cryptococcus neoformans var. grubii. 
  • Population genetic structure of Arabidopsis lyrata in Europe. 
  • Population genetics of a trochid gastropod broadens picture of Caribbean Sea connectivity. 
  • Population genetics of tandem trypsin inhibitor genes in Arabidopsis species with contrasting ecology and life history. 
  • Population genomics in South East Asia captures unexpectedly high carrier frequency for treatable inherited disorders. 
  • Population history in Arabidopsis halleri using multilocus analysis. 
  • Population perspectives on functional genomic variation in yeast. 
  • Population-based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene for high-grade serous ovarian cancer. 
  • Positive selection driving diversification in plant secondary metabolism. 
  • Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies. 
  • Potentially functional single nucleotide polymorphisms in the core nucleotide excision repair genes and risk of squamous cell carcinoma of the head and neck. 
  • Potentially functional variants of ERAP1, PSMF1 and NCF2 in the MHC-I-related pathway predict non-small cell lung cancer survival. 
  • Predictable patterns of constraint among anthocyanin-regulating transcription factors in Ipomoea. 
  • Predictors of consent to pharmacogenomics testing in the IDEAL study. 
  • Predictors of variation in serum IGF1 and IGFBP3 levels in healthy African American and white men. 
  • Presence of diverse human immunodeficiency virus type 1 viral variants in Cameroon. 
  • Prevalence of chemokine and chemokine receptor polymorphisms in seroprevalent children with symptomatic HIV-1 infection in the United States. 
  • Prevalence of clinical isolates of Cryptococcus gattii serotype C among patients with AIDS in Sub-Saharan Africa. 
  • Prevalence of hepatitis B antiviral drug resistance variants in North American patients with chronic hepatitis B not receiving antiviral treatment. 
  • Programmed evolution for optimization of orthogonal metabolic output in bacteria. 
  • Prospective dosing of warfarin based on cytochrome P-450 2C9 genotype. 
  • Prostate cancer in men of African origin. 
  • Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism. 
  • Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension. 
  • Protein Quantitative Trait Loci Analysis Identifies Genetic Variation in the Innate Immune Regulator TOLLIP in Post-Lung Transplant Primary Graft Dysfunction Risk. 
  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. 
  • Puzzling role of genetic risk factors in human longevity: "risk alleles" as pro-longevity variants. 
  • QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival. 
  • Quality control in the flow cytometric measurement of T-lymphocyte subsets: the multicenter AIDS cohort study experience. The Multicenter AIDS Cohort Study Group. 
  • Quantifying effects of environmental and geographical factors on patterns of genetic differentiation. 
  • Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants. 
  • Quantitation of hepatitis B viremia and emergence of YMDD variants in patients with chronic hepatitis B treated with lamivudine. 
  • Quantitative genetic variation in CD19 expression correlates with autoimmunity. 
  • RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression. 
  • RNA sequencing of isolated cell populations expressing human APOL1 G2 risk variant reveals molecular correlates of sickle cell nephropathy in zebrafish podocytes. 
  • RNase 1 genes from the family Sciuridae define a novel rodent ribonuclease cluster. 
  • Race, common genetic variation, and therapeutic response disparities in heart failure. 
  • Rapid changes in the gut microbiome during human evolution. 
  • Rare Things Being Common: Implications for Common Genetic Variants in Rare Diseases Like Long-QT Syndrome. 
  • Rare and low-frequency coding variants alter human adult height 
  • Rare coding variants and X-linked loci associated with age at menarche. 
  • Rare functional genetic variants in COL7A1, COL6A5, COL1A2 and COL5A2 frequently occur in Chiari Malformation Type 1. 
  • Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. 
  • Rare-variant collapsing analyses for complex traits: guidelines and applications. 
  • Reactivity of avian RNA tumor viruses with lectins. 
  • Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype. 
  • Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity. 
  • Receptor Switching in Newly Evolved Adeno-associated Viruses. 
  • Recognition of HLA-A2 mutant and variant target cells by an HLA-A2 allospecific human cytotoxic T lymphocyte line. 
  • Recombination modulates how selection affects linked sites in Drosophila. 
  • Recombining without Hotspots: A Comprehensive Evolutionary Portrait of Recombination in Two Closely Related Species of Drosophila. 
  • Reconciling extreme branch length differences: decoupling time and rate through the evolutionary history of filmy ferns 
  • Recurrent polyploid origins and chloroplast phylogeography in the Arabis holboellii complex (Brassicaceae). 
  • Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene. 
  • Reduced selective constraint in endosymbionts: elevation in radical amino acid replacements occurs genome-wide. 
  • Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. 
  • Refugial isolation and range expansions drive the genetic structure of Oxyria sinensis (Polygonaceae) in the Himalaya-Hengduan Mountains. 
  • Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk. 
  • Relationship of disease-associated gene expression to cardiac phenotype is buffered by genetic diversity and chromatin regulation. 
  • Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery. 
  • Relaxed selection among duplicate floral regulatory genes in Lamiales. 
  • Remaining flexible in old alliances: functional plasticity in constrained mutualisms. 
  • Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection. 
  • Repeated phenotypic changes highlight molecular targets of convergent evolution. 
  • Repeated range expansion and glacial endurance of Potentilla glabra (Rosaceae) in the Qinghai-Tibetan plateau. 
  • Replicated Landscape Genomics Identifies Evidence of Local Adaptation to Urbanization in Wood Frogs. 
  • Report on the 6th African Society of Human Genetics (AfSHG) Meeting, March 12-15, 2009, Yaounde, Cameroon. 
  • Review of evidence for genetic testing for CYP450 polymorphisms in management of patients with nonpsychotic depression with selective serotonin reuptake inhibitors. 
  • Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci. 
  • S-allele diversity in a natural population of Physalis crassifolia (Solanaceae) (ground cherry) assessed by RT-PCR. 
  • SIV infection duration largely determines broadening of neutralizing antibody response in macaques. 
  • SLC6A4 variation and citalopram response. 
  • SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development. 
  • SNiPA: an interactive, genetic variant-centered annotation browser. 
  • Saccharomyces cerevisiae: population divergence and resistance to oxidative stress in clinical, domesticated and wild isolates. 
  • Searching for causal relationships of glioma: a phenome-wide Mendelian randomisation study. 
  • Secrets of the perioptome: new tools for a new concept. 
  • Seed after-ripening and dormancy determine adult life history independently of germination timing. 
  • Selection for character displacement is constrained by the genetic architecture of floral traits in the ivyleaf morning glory. 
  • Selection of HIV Envelope Strains for Standardized Assessments of Vaccine-Elicited Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies. 
  • Selective sweeps and intercontinental migration in the cosmopolitan moss Ceratodon purpureus (Hedw.) Brid. 
  • Semi-automated assembly of high-quality diploid human reference genomes. 
  • Sequence context of indel mutations and their effect on protein evolution in a bacterial endosymbiont. 
  • Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. 
  • Sequence divergence of coiled coils--structural rods, myosin filament packing, and the extraordinary conservation of cohesins. 
  • Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor. 
  • Sequence signatures of a recent chromosomal rearrangement in Drosophila mojavensis. 
  • Sequence variants in the transforming growth beta-induced factor (TGIF) gene are not associated with high myopia. 
  • Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men. 
  • Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels. 
  • Sequence variations in DNA repair gene XPC is associated with lung cancer risk in a Chinese population: a case-control study. 
  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. 
  • Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity. 
  • Sequencing studies in human genetics: design and interpretation. 
  • Serotonin transporter gene moderates the development of emotional problems among children following bullying victimization. 
  • Serotonin transporter genetic variation and the response of the human amygdala. 
  • Serotonin. 
  • Serum lipids in the GENECARD study of coronary artery disease identify quantitative trait loci and phenotypic subsets on chromosomes 3q and 5q. 
  • Sex-biased admixture and assortative mating shape genetic variation and influence demographic inference in admixed Cabo Verdeans. 
  • Sex-dependent effect of APOE on Alzheimer's disease and other age-related neurodegenerative disorders. 
  • SgD-CNV, a database for common and rare copy number variants in three Asian populations. 
  • Shared genetic variants for polypoidal choroidal vasculopathy and typical neovascular age-related macular degeneration in East Asians. 
  • Shift in S-layer protein expression responsible for antigenic variation in Campylobacter fetus. 
  • Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz. 
  • Signatures of demography and recombination at coding genes in naturally-distributed populations of Arabidopsis lyrata subsp. petraea. 
  • Simian immunodeficiency virus (SIV) envelope quasispecies transmission and evolution in infant rhesus macaques after oral challenge with uncloned SIVmac251: increased diversity is associated with neutralizing antibodies and improved survival in previously immunized animals. 
  • Simple models of genomic variation in human SNP density. 
  • Single origin and subsequent diversification of central Andean endemic Umbilicaria species. 
  • Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. 
  • Smooth nonparametric maximum likelihood estimation for population pharmacokinetics, with application to quinidine. 
  • Snapshot of the allele-specific variation in human gene expression. 
  • Social behavior shapes the chimpanzee pan-microbiome 
  • Sources of variability in John Henryism. 
  • Spatial Genetic Structure of the Abundant and Widespread Peatmoss Sphagnum magellanicum Brid. 
  • Spatial models for hybrid zones. 
  • Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus. 
  • Speciation on a local geographic scale: the evolution of a rare rock outcrop specialist in Mimulus. 
  • Spectrum of neurodevelopmental disease associated with the GNAO1 guanosine triphosphate-binding region. 
  • Sphagnum physiology in the context of changing climate: emergent influences of genomics, modelling and host-microbiome interactions on understanding ecosystem function. 
  • Spontaneous deletions and duplications of sequences in the genome of cowpox virus. 
  • Sporadic, Global Linkage Disequilibrium Between Unlinked Segregating Sites. 
  • Statistical analysis of antigen receptor spectratype data. 
  • Statistical genetics of an annual plant, Impatiens capensis. I. Genetic basis of quantitative variation. 
  • Stereoselective Ketamine Metabolism by Genetic Variants of Cytochrome P450 CYP2B6 and Cytochrome P450 Oxidoreductase. 
  • Streamlined Subpopulation, Subtype, and Recombination Analysis of HIV-1 Half-Genome Sequences Generated by High-Throughput Sequencing. 
  • Stress: a possible link between genetics, epigenetics, and childhood asthma. 
  • Structural analysis of an HLA-B7 antigen variant detected by cytotoxic T lymphocytes. 
  • Structural variants can be more informative for disease diagnostics, prognostics and translation than current SNP mapping and exon sequencing. 
  • Structure and immune recognition of trimeric pre-fusion HIV-1 Env. 
  • Structure of the human allelic glutathione S-transferase-pi gene variant, hGSTP1 C, cloned from a glioblastoma multiforme cell line. 
  • Studying genetic resilience to improve human health. 
  • Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals. 
  • Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8. 
  • Survey of variation in human transcription factors reveals prevalent DNA binding changes. 
  • Survival prediction in patients with glioblastoma multiforme by human telomerase genetic variation. 
  • Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility. 
  • Systems Biology of Phenotypic Robustness and Plasticity. 
  • Systems biology of robustness and homeostatic mechanisms. 
  • T-Cell receptor Vbeta repertoire CDR3 length diversity differs within CD45RA and CD45RO T-cell subsets in healthy and human immunodeficiency virus-infected children. 
  • T296----M, a common mutation causing mild hemophilia B in the Amish and others: founder effect, variability in factor IX activity assays, and rapid carrier detection. 
  • TERC is not a major gene in human neural tube defects. 
  • TGFβ1 Genetic Variants Predict Clinical Outcomes of HPV-Positive Oropharyngeal Cancer Patients after Definitive Radiotherapy. 
  • TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype. 
  • TSPEAR variants are primarily associated with ectodermal dysplasia and tooth agenesis but not hearing loss: A novel cohort study. 
  • Taking cardiovascular genetic association studies to the next level. 
  • Tamoxifen pharmacogenomics: the role of CYP2D6 as a predictor of drug response. 
  • Tandemly arranged variant 5S ribosomal RNA genes in the yeast Saccharomyces cerevisiae. 
  • Targeted sequencing in chromosome 17q linkage region identifies familial glioma candidates in the Gliogene Consortium. 
  • Telomere structure and maintenance gene variants and risk of five cancer types. 
  • Temporal Stability of Molecular Diversity Measures in Natural Populations of Drosophila pseudoobscura and Drosophila persimilis. 
  • Testing Rare-Variant Association without Calling Genotypes Allows for Systematic Differences in Sequencing between Cases and Controls. 
  • Testing morphological concepts of orders of pleurocarpous mosses (Bryophyta) using phylogenetic reconstructions based on TRNL-TRNF and RPS4 sequences. 
  • The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory. 
  • The DNA sequence and biological annotation of human chromosome 1. 
  • The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial. 
  • The Influenza B Virus Hemagglutinin Head Domain Is Less Tolerant to Transposon Mutagenesis than That of the Influenza A Virus. 
  • The International HapMap Project. 
  • The Intolerance of Regulatory Sequence to Genetic Variation Predicts Gene Dosage Sensitivity. 
  • The North Carolina Experience with Mucopolysaccharidosis Type I Newborn Screening. 
  • The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers. 
  • The SSV Evaluation System: A Tool to Prioritize Short Structural Variants for Studies of Possible Regulatory and Causal Variants. 
  • The Snail's Charm. 
  • The Sox10(Dom) mouse: modeling the genetic variation of Waardenburg-Shah (WS4) syndrome. 
  • The Time Scale of Recombination Rate Evolution in Great Apes. 
  • The beta3 subunit of the Na+,K+-ATPase mediates variable nociceptive sensitivity in the formalin test. 
  • The case for strategic international alliances to harness nutritional genomics for public and personal health. 
  • The clinical significance of tenascin-C splice variant expression in chondrosarcoma. 
  • The cloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system. 
  • The contribution of admixture to primate evolution. 
  • The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans. 
  • The effect of SNCA 3' region on the levels of SNCA-112 splicing variant. 
  • The effects of quantitative fecundity in the haploid stage on reproductive success and diploid fitness in the aquatic peat moss Sphagnum macrophyllum. 
  • The evolution of transcriptional regulation in eukaryotes. 
  • The evolutionary forest algorithm. 
  • The extent of amino-terminal heterogeneity in rabbit fast skeletal muscle troponin T. 
  • The functional consequences of genetic variation on tyrosine hydroxylase (TH) expression 
  • The genetic architecture of biofilm formation in a clinical isolate of Saccharomyces cerevisiae. 
  • The genetic architecture of the human cerebral cortex. 
  • The genetic architecture of type 2 diabetes. 
  • The genetic contributions of SNCA and LRRK2 genes to Lewy Body pathology in Alzheimer's disease. 
  • The genetic structure and diversity of the A and B mating-type genes from the tropical oyster mushroom, Pleurotus djamor. 
  • The genomics of speciation in Drosophila: diversity, divergence, and introgression estimated using low-coverage genome sequencing. 
  • The geography of malaria genetics in the Democratic Republic of Congo: A complex and fragmented landscape. 
  • The impact of caspase-12 on susceptibility to candidemia. 
  • The importance of dynamic re-analysis in diagnostic whole exome sequencing. 
  • The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. 
  • The intolerance to functional genetic variation of protein domains predicts the localization of pathogenic mutations within genes. 
  • The meaning of genetic research results: reflections from individuals with and without a known genetic disorder. 
  • The missense of smell: functional variability in the human odorant receptor repertoire. 
  • The molecular basis of quantitative genetic variation in central and secondary metabolism in Arabidopsis. 
  • The neurobiology of individual differences in complex behavioral traits. 
  • The origin and evolution of animal appendages. 
  • The origin of helping: the role of variability in reproductive potential. 
  • The origins and genomic diversity of American Civil War Era smallpox vaccine strains. 
  • The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa. 
  • The quick and the dead: microbial demography at the yeast thermal limit. 
  • The rise of genomic profiling in ovarian cancer. 
  • The role of CD4-Lck in T-cell receptor antagonism: evidence for negative signaling. 
  • The roles of positive and negative selection in the molecular evolution of insect endosymbionts. 
  • The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. 
  • The spatial scale of genetic subdivision in populations of Ifremeria nautilei, a hydrothermal-vent gastropod from the southwest Pacific. 
  • The tRNA-Tyr gene family of Saccharomyces cerevisiae: agents of phenotypic variation and position effects on mutation frequency. 
  • The thermolabile variant of methylenetetrahydrofolate reductase (MTHFR) is not a major risk factor for neural tube defect in American Caucasians. The NTD Collaborative Group. 
  • The transcriptional landscape of Shh medulloblastoma. 
  • Theoretical and practical advances in genome halving. 
  • Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs. 
  • Tissue-specific expression from CaMV 35S enhancer subdomains in early stages of plant development. 
  • Toward a Wolbachia multilocus sequence typing system: discrimination of Wolbachia strains present in Drosophila species. 
  • Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus. 
  • Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection. 
  • Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. 
  • Transcriptional diversity during lineage commitment of human blood progenitors. 
  • Transcriptome analysis reveals novel patterning and pigmentation genes underlying Heliconius butterfly wing pattern variation. 
  • Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations. 
  • Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys. 
  • Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences. 
  • Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype. 
  • Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. 
  • U1 small nuclear RNA variants differentially form ribonucleoprotein particles in vitro. 
  • Ultra-rare genetic variation in common epilepsies: a case-control sequencing study. 
  • Understanding human variation in infectious disease susceptibility through clinical and cellular GWAS. 
  • Unique expression of a sporophytic character on the gametophytes of notholaenid ferns (Pteridaceae). 
  • Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans. 
  • Use of Pharmacogenetic Information in the Treatment of Cardiovascular Disease. 
  • Using common genetic variation to examine phenotypic expression and risk prediction in 22q11.2 deletion syndrome. 
  • Uterine Fibroids: Burden and Unmet Medical Need. 
  • Vaccine development for HIV infection. 
  • Vaccine-induced neutralizing antibodies directed in part to the simian immunodeficiency virus (SIV) V2 domain were unable to protect rhesus monkeys from SIV experimental challenge. 
  • Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG). 
  • Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants. 
  • Variable phenotypic expression of mutations in genes of the immune system. 
  • Variant genotypes of CDKN1A and CDKN1B are associated with an increased risk of breast cancer in Chinese women. 
  • Variant of Bartter's syndrome with a distal tubular rather than loop of Henle defect. 
  • Variant-specific inflation factors for assessing population stratification at the phenotypic variance level. 
  • Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, and West Africans. 
  • Variation and fitness costs for tolerance to different types of herbivore damage in Boechera stricta genotypes with contrasting glucosinolate structures. 
  • Variation and selection in neural function. 
  • Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer. 
  • Variation in Recombination Rate: Adaptive or Not? 
  • Variation in olfactory neuron repertoires is genetically controlled and environmentally modulated. 
  • Variation in the fitness effects of mutations with population density and size in Escherichia coli. 
  • Variations in IBD (ACAD8) in children with elevated C4-carnitine detected by tandem mass spectrometry newborn screening. 
  • Variations in Prkdc and susceptibility to benzene-induced toxicity in mice. 
  • Variations of cardiovascular disease associated genes exhibit sex-dependent influence on human longevity. 
  • VarioWatch: providing large-scale and comprehensive annotations on human genomic variants in the next generation sequencing era. 
  • Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation. 
  • Virulence genes of poxviruses and reoviruses. 
  • What can patterns of differentiation across plant genomes tell us about adaptation and speciation? 
  • When two is better than one. 
  • Which evolutionary processes influence natural genetic variation for phenotypic traits? 
  • Whole-genome analysis informs breast cancer response to aromatase inhibition. 
  • Wide variation in the multiplicity of HIV-1 infection among injection drug users. 
  • Within- and between- subject variability of indices from the closing volume and flow volume traces. 
  • Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale. 
  • [Analysis of genetic heterogeneity of bronchial asthma in relation with the age at the onset of disease] 
  • [Genetic structure of geographically different populations of candida albicans]. 
  • alpha AD alpha hybrids of Cryptococcus neoformans: evidence of same-sex mating in nature and hybrid fitness. 
  • alpha-Synuclein gene haplotypes are associated with Parkinson's disease. 
  • apex: phylogenetics with multiple genes. 
  • gsSKAT: Rapid gene set analysis and multiple testing correction for rare-variant association studies using weighted linear kernels. 
  • optix Drives the Repeated Convergent Evolution of Butterfly Wing Pattern Mimicry 
  • rbcL and matK earn two thumbs up as the core DNA barcode for ferns 
  • rqt: an R package for gene-level meta-analysis. 
  • α satellite DNA variation and function of the human centromere. 
• 

  Keywords of People

  • Abbruzzese, James, D. C. I. Distinguished Professor of Medical Oncology, Medicine, Medical Oncology
  • Alberts, Susan C., Robert F. Durden Distinguished Professor of Biology, Duke Science & Society
  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Erickson, Harold Paul, Professor Emeritus of Cell Biology, Cell Biology
  • Grambow, Steven C., Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Kelsoe, Garnett H., James B. Duke Distinguished Professor of Immunology, Immunology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Immunology
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology, Cell Biology
  • Magwene, Paul Mitaari, Professor of Biology, Biology
  • Mitchell-Olds, Thomas, Newman Ivey White Distinguished Professor of Biology, Biology
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Noor, Mohamed A. F., Professor of Biology, Duke Science & Society
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology
  • Orlando, Lori Ann, Professor of Medicine, Medicine, General Internal Medicine
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics,, Molecular Genetics and Microbiology
  • Schultz, Thomas F., Assistant Professor of the Practice of Marine Molecular Conservation, Marine Science and Conservation
  • Shinohara, Mari L., Associate Professor of Immunology, Cell Biology
  • Soderling, Scott Haydn, George Barth Geller Distinguished Professor of Molecular Biology, Cell Biology
  • Tung, Jenny, Associate Professor of Evolutionary Anthropology, Duke Science & Society
  • Wernegreen, Jennifer Jo, Lee Hill Snowdon Associate Professor, Environmental Sciences and Policy
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
  • Yan, Hai, Adjunct Professor of Pathology, Pathology
  • Yoder, Anne Daphne, Braxton Craven Distinguished Professor of Evolutionary Biology, Duke Science & Society