Vasodilation

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  Subject Areas on Research

  • A VEGF trap inhibits the beneficial effect of bFGF on vasoreactivity in corporal tissues of hypercholesterolemic rabbits. 
  • Acute local subcutaneous VEGF165 injection for augmentation of skin flap viability: efficacy and mechanism. 
  • Acute reductions in haematocrit increase flow-mediated dilatation independent of resting nitric oxide bioavailability in humans. 
  • Alpha adrenergic vasoconstriction and nitroglycerin vasodilation of large coronary arteries in the conscious dog. 
  • Amrinone: its effect on vascular resistance and capacitance in human subjects. 
  • An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation. 
  • Analysis of responses to bradykinin in the pulmonary vascular bed of the cat. 
  • Analysis of responses to substance P in the pulmonary vascular bed of the cat. 
  • Anticoagulant responses to thrombin are enhanced during regression of atherosclerosis in monkeys. 
  • Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia. 
  • Antiplatelet Effect Durability of a Novel, 24-Hour, Extended-Release Prescription Formulation of Acetylsalicylic Acid in Patients With Type 2 Diabetes Mellitus. 
  • Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation. 
  • Arterial response to shear stress critically depends on endothelial TRPV4 expression. 
  • Ascites as a marker for the hyperdynamic heart of Laennec's cirrhosis. 
  • Assessment of whole-brain vasodilatory capacity with acetazolamide challenge at 1.5 T using dynamic contrast imaging with frequency-shifted burst. 
  • Behavioral approaches to Raynaud's disease. 
  • Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease. 
  • Bicarbonate-dependent superoxide release and pulmonary artery tone. 
  • Bradykinin type 2 receptor BE1 genotype influences bradykinin-dependent vasodilation during angiotensin-converting enzyme inhibition. 
  • Calcium-activated potassium channels mask vascular dysfunction associated with oxidized LDL exposure in rabbit aorta. 
  • Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species. 
  • Cardioprotective role of S-nitrosylated hemoglobin from rbc. 
  • Cardiovascular function in normotensive offspring of persons with essential hypertension and black race. 
  • Cerebral vasodilation and vasoconstriction associated with acute anxiety. 
  • Changes in plasma volume associated with mental stress ischemia in patients with coronary artery disease. 
  • Changing the Carburetor Without Changing the Plugs: The Intersection of Stock Car Racing With Mechanically Assisted Circulation. 
  • Clarifying the Relative Impacts of Vascular and Nerve Injury That Culminate in Erectile Dysfunction in a Pilot Study Using a Rat Model of Prostate Irradiation and a Thrombopoietin Mimetic. 
  • Clinical significance of perfusion defects by thallium-201 single photon emission tomography following oral dipyridamole early after coronary angioplasty. 
  • Comparative effects of L-NNA and alkyl esters of L-NNA on pulmonary vasodilator responses to ACh, BK, and SP. 
  • Comparison of relaxation responses to multiple vasodilators in TxA(2)-analog and endothelin-1-precontracted pulmonary arteries. 
  • Complex Role for E-Prostanoid 4 Receptors in Hypertension. 
  • Contributions of neuroendocrine and local autocrine-paracrine mechanisms to the pathophysiology and pharmacology of congestive heart failure. 
  • Coronary Microvascular Dysfunction as a Mechanism of Angina in Severe AS: Prospective Adenosine-Stress CMR Study. 
  • Coronary input impedance is constant during systole and diastole. 
  • Correlation of light-flicker-induced retinal vasodilation and retinal vascular caliber measurements in diabetes. 
  • Diastolic coronary resistance and capacitance are independent of the duration of diastole. 
  • Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease. 
  • Diltiazem preserves direct vasodilator response but fails to suppress intimal proliferation in rat allograft coronary artery disease. 
  • Dynamic Responses in Retinal Vessel Caliber With Flicker Light Stimulation and Risk of Diabetic Retinopathy and Its Progression. 
  • Dynamic changes in retinal vessel diameter during acute hyperglycemia in type 1 diabetes. 
  • Dynamic denitrosylation via S-nitrosoglutathione reductase regulates cardiovascular function. 
  • Effect of anger provocation on endothelium-dependent and -independent vasodilation. 
  • Effect of cardiac cycle on ultrasound assessment of endothelial function. 
  • Effect of denervation on endothelium-derived relaxing factor-dependent relaxation in the rat cremaster muscle. 
  • Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. 
  • Effect of the nitric oxide donor V-PYRRO/NO on portal pressure and sinusoidal dynamics in normal and cirrhotic mice. 
  • Effects of U-37883A, a vascular selective KATP+ channel antagonist, in the pulmonary and hindlimb circulation. 
  • Effects of atrial natriuretic peptide on the coronary arterial vasculature in humans. 
  • Effects of cardiopulmonary bypass and circulatory arrest on endothelium-dependent vasodilation in the lung. 
  • Effects of pulsatile perfusion on human saphenous vein vasoreactivity: a preliminary report. 
  • Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function. 
  • Endothelial dysfunction and the risk of hypertension: the multi-ethnic study of atherosclerosis. 
  • Endothelial superoxide production is altered in sheep programmed by early gestation dexamethasone exposure. 
  • Endothelium-dependent relaxations in canine coronary arteries are enhanced in early heart failure and persist in recovery. 
  • Enhanced vasorelaxation by overexpression of beta 2-adrenergic receptors in large arteries. 
  • Ethnic differences in forearm vasodilator capacity. 
  • Evolution of adverse changes in stored RBCs. 
  • Evolution of plus disease in retinopathy of prematurity: quantification by ROPtool. 
  • Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans. 
  • Extrapulmonary effects of inhaled nitric oxide: role of reversible S-nitrosylation of erythrocytic hemoglobin. 
  • Fibrosis-related biomarkers and large and small vessel disease: the Cardiovascular Health Study. 
  • Flicker light-induced retinal vasodilation in diabetes and diabetic retinopathy. 
  • Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. 
  • Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature. 
  • GLOBAL REACH 2018: intra-arterial vitamin C improves endothelial-dependent vasodilatory function in humans at high altitude. 
  • Gene transfer of endothelial nitric oxide synthase improves relaxation of carotid arteries from diabetic rabbits. 
  • Global REACH 2018: High Blood Viscosity and Hemoglobin Concentration Contribute to Reduced Flow-Mediated Dilation in High-Altitude Excessive Erythrocytosis. 
  • Hemoglobin and nitric oxide. 
  • Hemoglobin, nitric oxide and molecular mechanisms of hypoxic vasodilation. 
  • Hostility, coronary risk, and alpha-adrenergic to beta-adrenergic receptor density ratio. 
  • How do red blood cells cause hypoxic vasodilation? The SNO-hemoglobin paradigm. 
  • How do red blood cells dilate blood vessels? 
  • Human Vascular Microphysiological System for in vitro Drug Screening. 
  • Impact of cinematic viewing on endothelial function. 
  • Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction. 
  • Impaired coronary vasodilation by magnetic resonance angiography is associated with advanced coronary artery calcification. 
  • Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. 
  • Increased oxygen extraction fraction is associated with prior ischemic events in patients with carotid occlusion. 
  • Influence of Zaprinast on vascular tone and vasodilator responses in the cat pulmonary vascular bed. 
  • Influence of blood pressure on retinal vascular caliber in young children. 
  • Influences of inflation rate and duration on vasodilatory effect by intermittent pneumatic compression in distant skeletal muscle. 
  • Inhaled nitric oxide selectively dilates pulmonary vasculature in adult patients with pulmonary hypertension, irrespective of etiology. 
  • Inhibition of nitric oxide synthase on brain oxygenation in anesthetized rats exposed to hyperbaric oxygen. 
  • Interrelations between contracting striated muscle and precapillary microvessels. 
  • Intracoronary basic fibroblast growth factor enhances myocardial collateral perfusion in dogs. 
  • Intracranial and extracranial blood flow during acute anxiety. 
  • Intradialytic hypertension and its association with endothelial cell dysfunction. 
  • Investigation of the role of prostaglandins in nitroglycerin-induced relaxation of isolated rabbit blood vessels. 
  • Ischemic limb necrosis in septic shock: What is the role of high-dose vasopressor therapy? 
  • L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits. 
  • L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans. 
  • Limits of detection of regional differences in vasodilated flow in viable myocardium by first-pass magnetic resonance perfusion imaging. 
  • Local Peroxynitrite Impairs Endothelial Transient Receptor Potential Vanilloid 4 Channels and Elevates Blood Pressure in Obesity. 
  • Magnetic resonance versus radionuclide pharmacological stress perfusion imaging for flow-limiting stenoses of varying severity. 
  • Management of systemic and pulmonary hypertension. 
  • Mechanical compression during repeated sustained isometric muscle contractions and hyperemic recovery in healthy young males. 
  • Mechanism of natriuresis during intrarenal infusion of prostaglandins. 
  • Mechanisms underlying cardiovascular defense reaction evoked by dorsal periaqueductal gray stimulation. 
  • Methylene blue inhibits neurogenic cholinergic vasodilator responses in the pulmonary vascular bed of the cat. 
  • Microparticles in cardiovascular disease pathophysiology and outcomes. 
  • Microvascular determinants of blood flow. 
  • Microvascular dilatation after haemodialysis is determined by the volume of fluid removed and fall in mean arterial pressure. 
  • Myocardial uptake and clearance of T1-201 in healthy subjects: comparison of adenosine-induced hyperemia and exercise stress. 
  • N omega-nitro-L-arginine methyl ester selectively inhibits pulmonary vasodilator responses to acetylcholine and bradykinin. 
  • Neural correlates of single-vessel haemodynamic responses in vivo. 
  • Nitric oxide in the human respiratory cycle. 
  • Normal and shear stresses influence the spatial distribution of intracellular adhesion molecule-1 expression in human umbilical vein endothelial cells exposed to sudden expansion flow. 
  • Novel versus traditional risk markers for diabetic retinopathy. 
  • Opposing hemodynamic effects of substance P on pulmonary vasculature in rabbits. 
  • Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm. 
  • Pannexin 1 channels control the hemodynamic response to hypoxia by regulating O2-sensitive extracellular ATP in blood. 
  • Pericyte constriction underlies capillary derecruitment during hyperemia in the setting of arterial stenosis. 
  • Pharmacologic Targeting of Red Blood Cells to Improve Tissue Oxygenation. 
  • Photoacoustic microscopy of microvascular responses to cortical electrical stimulation. 
  • Potential mechanisms for reduced delivery of nitric oxide to peripheral tissues in diabetes mellitus. 
  • Pro: Vasopressin is the vasoconstrictor of choice after cardiopulmonary bypass. 
  • Probing the mechanisms of intradialytic hypertension: a pilot study targeting endothelial cell dysfunction. 
  • Prognostic Implications of Blunted Feature-Tracking Global Longitudinal Strain During Vasodilator Cardiovascular Magnetic Resonance Stress Imaging. 
  • Progressive Retinal Vasodilation in Patients With Type 1 Diabetes: A Longitudinal Study of Retinal Vascular Geometry. 
  • Pulmonary vascular impedance analysis of adaptation to chronically elevated blood flow in the awake dog. 
  • Pulmonary vasodilation by ketamine is mediated in part by L-type calcium channels. 
  • Pulmonary vasodilator response to vagal stimulation is blocked by N omega-nitro-L-arginine methyl ester in the cat. 
  • Pulmonary vasodilator responses to RP 52891 are mediated by activation of a glibenclamide-sensitive K+ATP channel. 
  • Pungent products from garlic activate the sensory ion channel TRPA1. 
  • Purine nucleotides contribute to pulmonary vasodilation caused by birth-related stimuli in the ovine fetus. 
  • Reactive hyperemia is associated with adverse clinical outcomes in heart failure. 
  • Reactive oxygen species mediate arachidonic acid-induced dilation in porcine coronary microvessels. 
  • Reduced beta 2-receptor mediated vasodilation in African Americans. 
  • Regional anesthesia for vascular access surgery. 
  • Regional brain blood flow in man during acute changes in arterial blood gases. 
  • Relative contribution of vasopressin and angiotensin II to the altered renal microcirculatory dynamics in two-kidney Goldblatt hypertension. 
  • Relaxin, a pleiotropic vasodilator for the treatment of heart failure. 
  • Reperfusion injury is reduced in skeletal muscle by inhibition of inducible nitric oxide synthase. 
  • Reproducibility of the retinal vascular response to flicker light in Asians. 
  • Response of finger circulation to energy equivalent combinations of magnitude and duration of vibration. 
  • Retinal Vessel Tortuosity and Its Relation to Traditional and Novel Vascular Risk Markers in Persons with Diabetes. 
  • Retinal microvascular structure and function in patients with risk factors of atherosclerosis and coronary artery disease. 
  • Retinal vascular caliber and brachial flow-mediated dilation: the Multi-Ethnic Study of Atherosclerosis. 
  • Role of K+ATP channels and EDRF in reactive hyperemia in the hindquarters vascular bed of cats. 
  • Role of nitric oxide in vasodilation in upstream muscle during intermittent pneumatic compression. 
  • S-nitrosohemoglobin is distinguished from other nitrosovasodilators by unique oxygen-dependent responses that support an allosteric mechanism of action. 
  • SNO-hemoglobin and hypoxic vasodilation. 
  • Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels. 
  • Sex-Specific Mechanisms of Resistance Vessel Endothelial Dysfunction Induced by Cardiometabolic Risk Factors. 
  • Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. 
  • Superoxide production, risk factors, and endothelium-dependent relaxations in human internal mammary arteries. 
  • Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex. 
  • Suppression of inflammatory disease activity in rheumatoid arthritis is associated with improvements in retinal microvascular health. 
  • Surviving Without Oxygen: How Low Can the Human Brain Go? 
  • Synergistic effect of shear stress and streptavidin-biotin on the expression of endothelial vasodilator and cytoskeleton genes. 
  • Systemic associations of dynamic retinal vessel analysis: a review of current literature. 
  • TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure. 
  • The desaturation response time of finger pulse oximeters during mild hypothermia. 
  • The effect of aspirin on endothelial progenitor cell biology: preliminary investigation of novel properties. 
  • The effect of rate of heating or cooling prior to heating on tumor and normal tissue microcirculatory blood flow. 
  • The in vitro reversal of histamine-induced vasodilation in the human internal mammary artery. 
  • Therapeutic implications of estrogen for cerebral vasospasm and delayed cerebral ischemia induced by aneurysmal subarachnoid hemorrhage. 
  • Transpulmonary flux of S-nitrosothiols and pulmonary vasodilation during nitric oxide inhalation: role of transport. 
  • Tumor necrosis factor-alpha antagonism with etanercept improves endothelial progenitor cell counts in patients with psoriasis: etanercept, vascular function and endothelial progenitor cells in psoriasis. 
  • UBC-Nepal expedition: upper and lower limb conduit artery shear stress and flow-mediated dilation on ascent to 5,050 m in lowlanders and Sherpa. 
  • Usefulness of retinal microvascular endothelial dysfunction as a predictor of coronary artery disease. 
  • Vascular and renal prostaglandins as counter-regulatory systems in heart failure. 
  • Vasoactive drugs produce selective changes in flow to experimental brain tumors. 
  • Vasodilator action of pentoxifylline on microcirculation of rat cremaster muscle. 
  • Vasodilatory state of decompensated cirrhosis: relation to hepatic dysfunction, ascites, and vasoactive substances. 
  • Vasopressin-mediated forearm vasodilation in normal humans. Evidence for a vascular vasopressin V2 receptor. 
  • Wheal and flare responses to opioids in humans. 
  • [Nphe1]nociceptin(1-13)-NH2 antagonizes nociceptin-induced hypotension, bradycardia, and hindquarters vasodilation in the anesthetized rat. 
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  Keywords of People

  • Jordt, Sven Eric, Associate Professor in Anesthesiology, Pharmacology & Cancer Biology