Viral Fusion Proteins
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Subject Areas on Research
- ARF1 regulates Nef-induced CD4 degradation.
- An inducible HIV type 1 gp41 HR-2 peptide-binding site on HIV type 1 envelope gp120.
- An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface.
- Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120.
- Attenuated poxvirus-based simian immunodeficiency virus (SIV) vaccines given in infancy partially protect infant and juvenile macaques against repeated oral challenge with virulent SIV.
- Constitutively active retinoid receptors exhibit interfamily and intrafamily promoter specificity.
- Effect of CD8+ lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239delta3-vaccinated rhesus macaques.
- Enhanced oncolytic activity of vesicular stomatitis virus encoding SV5-F protein against prostate cancer.
- Fusigenic viral liposome for gene therapy in cardiovascular diseases.
- Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
- Herpes simplex virus proteins ICP27 and UL47 associate with polyadenylate-binding protein and control its subcellular distribution.
- Immunogens Modeling a Fusion-Intermediate Conformation of gp41 Elicit Antibodies to the Membrane Proximal External Region of the HIV Envelope Glycoprotein.
- Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251.
- Phage display screening for peptides that inhibit polyglutamine aggregation.
- Propensity for a leucine zipper-like domain of human immunodeficiency virus type 1 gp41 to form oligomers correlates with a role in virus-induced fusion rather than assembly of the glycoprotein complex.
- Pseudotyped viruses permit rapid detection of neutralizing antibodies in human and equine serum against Venezuelan equine encephalitis virus.
- Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein.
- Respiratory Syncytial Virus Vaccination during Pregnancy and Effects in Infants.
- SIV vaccine protection of rhesus monkeys.
- Safety and Immunogenicity of a Respiratory Syncytial Virus Fusion (F) Protein Nanoparticle Vaccine in Healthy Third-Trimester Pregnant Women and Their Infants.
- Six-helix bundle assembly and characterization of heptad repeat regions from the F protein of Newcastle disease virus.
- Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.
- The bacteriophage T4 insertion/substitution vector system. A method for introducing site-specific mutations into the virus chromosome.
- The stoichiometry of trimeric SIV glycoprotein interaction with CD4 differs from that of anti-envelope antibody Fab fragments.
- VSV transmembrane domain (TMD) peptide promotes PEG-mediated fusion of liposomes in a conformationally sensitive fashion.