Vitamin D

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  Subject Areas on Research

  • (1-34) Parathyroid hormone infusion acutely lowers fibroblast growth factor 23 concentrations in adult volunteers. 
  • 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. 
  • 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. 
  • 25-Hydroxyvitamin D levels and survival in advanced pancreatic cancer: findings from CALGB 80303 (Alliance). 
  • A Comparison Study of Vitamin D Deficiency among Older Adults in China and the United States. 
  • A PHEX gene mutation is responsible for adult-onset vitamin D-resistant hypophosphatemic osteomalacia: evidence that the disorder is not a distinct entity from X-linked hypophosphatemic rickets. 
  • A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization. 
  • A randomized intervention study to evaluate the effect of calcitriol therapy on the renin-angiotensin system in diabetes. 
  • A review of micronutrients in sepsis: the role of thiamine, l-carnitine, vitamin C, selenium and vitamin D. 
  • A systematic review of morphea treatments and therapeutic algorithm. 
  • Abnormal bone turnover in cystic fibrosis adults. 
  • Activated injectable vitamin D and hemodialysis survival: a historical cohort study. 
  • Adiposity, cardiometabolic risk, and vitamin D status: the Framingham Heart Study. 
  • An overview of calcium homeostasis in humans. 
  • Assessing the effects of ultraviolet radiation, residential greenness and air pollution on vitamin D levels: A longitudinal cohort study in China. 
  • Association Between Serum Vitamin D Level and Rates of Structural and Functional Glaucomatous Progression. 
  • Association between low levels of 1,25-dihydroxyvitamin D and breast cancer risk. 
  • Association of Serum Vitamins with Eczema in US Adults (NHANES 2005-2006). 
  • Association of Vitamin D Levels With Outcome in Patients With Melanoma After Adjustment For C-Reactive Protein. 
  • Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study. 
  • Baseline Characteristics of the Vitamin D and Type 2 Diabetes (D2d) Study: A Contemporary Prediabetes Cohort That Will Inform Diabetes Prevention Efforts. 
  • Beyond minerals and parathyroid hormone: role of active vitamin D in end-stage renal disease. 
  • Biomarkers of Mineral and Bone Metabolism and 20-Year Risk of Hospitalization With Infection: The Atherosclerosis Risk in Communities Study. 
  • Calcium and vitamin D intakes may be positively associated with brain lesions in depressed and nondepressed elders. 
  • Changes in bone health and skeletal-related events following implementation of a multidisciplinary consensus statement guiding surveillance and treatment of men undergoing androgen deprivation therapy for prostate cancer. 
  • Chronic kidney disease, hypovitaminosis D, and mortality in the United States. 
  • Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study. 
  • Circulating vitamin D concentrations and risk of breast and prostate cancer: a Mendelian randomization study. 
  • Clinical risk factors for recurrent fracture after hip fracture: a prospective study. 
  • Common genetic determinants of vitamin D insufficiency: a genome-wide association study. 
  • Comparison of cost-effectiveness of vitamin D screening with that of universal supplementation in preventing falls in community-dwelling older adults. 
  • Comparison of dietary and lifestyle habits among stage III and metastatic colorectal cancer patients: findings from CALGB 89803 and CALGB 80405. 
  • Comparison of two long-term chemotherapy regimens, with or without agents to modify skeletal repair, in multiple myeloma. 
  • Consumption of dairy products and the risk of breast cancer: a review of the literature. 
  • Dairy, calcium, vitamin D and ovarian cancer risk in African-American women. 
  • Deflazacort in Duchenne muscular dystrophy: a comparison of two different protocols. 
  • Determinants of 25-hydroxyvitamin D levels in African-American and Caucasian male veterans. 
  • Dietary interventions and nutritional supplements for heart failure: a systematic appraisal and evidence map. 
  • Diminished and erratic absorption of ergocalciferol in adult cystic fibrosis patients. 
  • Discovering the obvious, damaging the defenseless. 
  • Disease activity, proteinuria, and vitamin D status in children with systemic lupus erythematosus and juvenile dermatomyositis. 
  • Disordered FGF23 and mineral metabolism in children with CKD. 
  • Distribution and correlates of serum 25-hydroxyvitamin D levels in a sample of patients with hip fracture. 
  • Drug uptake and pharmacological modulation of drug sensitivity in leukemia by AQP9. 
  • Dysregulated mineral metabolism in patients with acute kidney injury and risk of adverse outcomes. 
  • Early prenatal vitamin D concentrations and social-emotional development in infants. 
  • Effect of antiepileptic drugs on bone density in ambulatory patients. 
  • Effect of vitamin D supplementation on cardiovascular risk in type 2 diabetes. 
  • Effects of Vitamin D Supplementation on C-peptide and 25-hydroxyvitamin D Concentrations at 3 and 6 Months. 
  • Effects of Vitamin D Supplementation on Insulin Sensitivity and Secretion in Prediabetes. 
  • Effects of Vitamin D2 Supplementation on Vitamin D3 Metabolism in Health and CKD. 
  • Effects of elevated lead and cadmium burdens on renal function and calcium metabolism. 
  • Effects of iron deficiency anemia and its treatment on fibroblast growth factor 23 and phosphate homeostasis in women. 
  • Effects of vitamin D insufficiency on bone mineral density in African American men. 
  • Elevated FGF-23 in a patient with rhabdomyolysis-induced acute kidney injury. 
  • Elevated calcium requirements for women and unique approaches to improving calcium adherence. 
  • Ensuring vitamin D supplementation in nursing home patients--a quality improvement project. 
  • Epistasis amongst PTPN2 and genes of the vitamin D pathway contributes to risk of juvenile idiopathic arthritis. 
  • Evaluation of a role for 1,25-dihydroxyvitamin D3 in the pathogenesis and treatment of X-linked hypophosphatemic rickets and osteomalacia. 
  • Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women. 
  • Evidence basis for integrated management of mineral metabolism in patients with end-stage renal disease. 
  • Evidence of a chemopreventive effect of progestin unrelated to ovulation on reproductive tract cancers in the egg-laying hen. 
  • Expert physician recommendations and current practice patterns for evaluating and treating men with osteoporotic hip fracture. 
  • Extraskeletal effects of vitamin D in older adults: cardiovascular disease, mortality, mood, and cognition. 
  • FGF-23 levels in patients with AKI and risk of adverse outcomes. 
  • FGF23 modifies the relationship between vitamin D and cardiac remodeling. 
  • FGF23 or PTH: which comes first in CKD ? 
  • Fibroblast Growth Factor 23 and Risk of CKD Progression in Children. 
  • Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease. 
  • Fibroblast growth factor 23 levels are elevated and associated with severe acute kidney injury and death following cardiac surgery. 
  • Genetic Variants Associated with Circulating Fibroblast Growth Factor 23. 
  • Genetic and environmental factors are associated with serum 25-hydroxyvitamin D concentrations in older African Americans. 
  • Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes. 
  • Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levels. 
  • Genetically low vitamin D concentrations and myopic refractive error: a Mendelian randomization study. 
  • Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. 
  • Health Outcomes With Vitamin D Supplementation-Reply. 
  • Host-Directed Therapies for Tuberculosis. 
  • How much vitamin D should I take? 
  • Hypercalciuria and altered intestinal calcium absorption occurring independently of vitamin D in incomplete distal renal tubular acidosis. 
  • Impact of 25-hydroxyvitamin D deficiency on perioperative parathyroid hormone kinetics and results in patients with primary hyperparathyroidism. 
  • Impact of activated vitamin D and race on survival among hemodialysis patients. 
  • Impact of activated vitamin D on insulin resistance in nondiabetic chronic kidney disease patients. 
  • Impact of vitamin D on pathological complete response and survival following neoadjuvant chemotherapy for breast cancer: a retrospective study. 
  • Implications of the Hemoglobin Glycation Index on the Diagnosis of Prediabetes and Diabetes. 
  • In HIV/hepatitis C virus co-infected patients, higher 25-hydroxyvitamin D concentrations were not related to hepatitis C virus treatment responses but were associated with ritonavir use. 
  • Increasing use of vitamin D supplementation in the chronic renal insufficiency cohort study. 
  • Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. 
  • Innovations in bones and stones. 
  • Integrating Research With Clinical Practice: Keeping It Simple. 
  • Interaction of Vitamin D and Corticosteroid Use in Hospitalized COVID-19 Patients: A Potential Explanation for Inconsistent Findings in the Literature. 
  • Interventions Against Disability in Frail Older Adults: Lessons Learned from Clinical Trials. 
  • Inverted U-shaped relationship between vitamin D and ever-reported eczema in US adults. 
  • Management of osteoporosis among home health and long-term care patients with a prior fracture. 
  • Maternal vitamin D, DNA methylation at imprint regulatory regions and offspring weight at birth, 1 year and 3 years. 
  • Mendelian randomisation study of the relationship between vitamin D and risk of glioma. 
  • Mineral metabolites and CKD progression in African Americans. 
  • Modifiers of Plasma 25-Hydroxyvitamin D and Chronic Kidney Disease Outcomes in Black Americans: The Jackson Heart Study. 
  • Molecular biology of the vitamin D hormone. 
  • Monitoring the randomized trials of the Women's Health Initiative: the experience of the Data and Safety Monitoring Board. 
  • NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition. 
  • Nephropathic Cystinosis: A Distinct Form of CKD-Mineral and Bone Disorder that Provides Novel Insights into the Regulation of FGF23. 
  • Newer knowledge of vitamin D and its metabolites in health and disease. 
  • Nocturnal heart rate and inflammation. 
  • Null association between vitamin D and PSA levels among black men in a vitamin D supplementation trial. 
  • Obesity-related asthma in children: A role for vitamin D. 
  • Osteoporosis screening and treatment among veterans with recent fracture after implementation of an electronic consult service. 
  • Osteoporosis. 
  • Outcomes of COVID-19: disparities in obesity and by ethnicity/race. 
  • Paricalcitol versus cinacalcet plus low-dose vitamin D therapy for the treatment of secondary hyperparathyroidism in patients receiving haemodialysis: results of the IMPACT SHPT study. 
  • Perioperative Serum 25-Hydroxyvitamin D Levels as a Predictor of Postoperative Opioid Use and Opioid Use Disorder: a Cohort Study. 
  • Plasma 25-Hydroxyvitamin D Concentrations Are Inversely Associated with All-Cause Mortality among a Prospective Cohort of Chinese Adults Aged ≥80 Years. 
  • Plasma 25-Hydroxyvitamin D Levels and Survival in Patients with Advanced or Metastatic Colorectal Cancer: Findings from CALGB/SWOG 80405 (Alliance). 
  • Plasma FGF23 levels increase rapidly after acute kidney injury. 
  • Post-transplant hypophosphatemia: Tertiary 'Hyper-Phosphatoninism'? 
  • Prediagnostic serum vitamin D and breast cancer. 
  • Predicted vitamin D status and colon cancer recurrence and mortality in CALGB 89803 (Alliance). 
  • Prevalence and predictors of osteoporosis treatment in nursing home residents with known osteoporosis or recent fracture. 
  • Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. 
  • Protocol for the Vitamin D Oral Replacement in Asthma (VDORA) study. 
  • Psoriasis. 
  • Race, Mineral Homeostasis and Mortality in Patients with End-Stage Renal Disease on Dialysis. 
  • Randomized trial of tamoxifen versus combined tamoxifen and octreotide LAR Therapy in the adjuvant treatment of early-stage breast cancer in postmenopausal women: NCIC CTG MA.14. 
  • Randomized trial of the anti-FGF23 antibody KRN23 in X-linked hypophosphatemia. 
  • Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus. 
  • Rare Complication of Sclerochoroidal Calcifications. 
  • Re: Epilepsy-associated bone mineral density loss should be prevented. 
  • Recent advances in the rapidly evolving field of fibroblast growth factor 23 in chronic kidney disease. 
  • Rectal cancer. 
  • Regulation of renal 25-hydroxyvitamin D-1-hydroxylase activity in the mouse after uninephrectomy. 
  • Regulation of zebrafish fin regeneration by vitamin D signaling. 
  • Relationship of low vitamin D status with positive, negative and cognitive symptom domains in people with first-episode schizophrenia. 
  • Relationship of vitamin D deficiency to clinical outcomes in critically ill patients. 
  • Reply to 'Comment on 'Dairy, calcium, vitamin D and ovarian cancer risk in African-American women''. 
  • Reply to Kim et al. 
  • Residential Greenness Alters Serum 25(OH)D Concentrations: A Longitudinal Cohort of Chinese Older Adults. 
  • Response to Letter to the Editor: Vitamin D status may help explain racial disparities in breast cancer hospitalization outcomes. 
  • Risk of hypercalcemia in blacks taking hydrochlorothiazide and vitamin D. 
  • Risk of secondary hyperparathyroidism after laparoscopic gastric bypass surgery in obese women. 
  • Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis. 
  • Safety and tolerability of high-dose daily vitamin D3 supplementation in the vitamin D and type 2 diabetes (D2d) study-a randomized trial in persons with prediabetes. 
  • Sarcopenia in Patients with Chronic Liver Disease: Can It Be Altered by Diet and Exercise? 
  • Serum 25-Hydroxyvitamin D, Albumin, and Mortality Among Chinese Older Adults: A Population-based Longitudinal Study. 
  • Serum Vitamin D Levels Affect Pathologic Complete Response in Patients Undergoing Neoadjuvant Systemic Therapy for Operable Breast Cancer. 
  • Serum levels of fibroblast growth factor 23 are elevated in patients with active Lupus nephritis. 
  • Severe obesity is associated with symptomatic presentation, higher parathyroid hormone levels, and increased gland weight in primary hyperparathyroidism. 
  • Short communication: Inadequate vitamin D exacerbates parathyroid hormone elevations in tenofovir users. 
  • Should activated vitamin D be used in patients with end-stage renal disease and low levels of parathyroid hormone? 
  • Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1alpha,25-dihydroxyvitamin D(3) in prostate cancer cells. 
  • The BraveNet prospective observational study on integrative medicine treatment approaches for pain. 
  • The HORIZON Recurrent Fracture Trial: design of a clinical trial in the prevention of subsequent fractures after low trauma hip fracture repair. 
  • The Influence of Vitamin D on Mammographic Density: Results from CALGB 70806 (Alliance) a Randomized Clinical Trial. 
  • The Interaction of Vitamin D and Corticosteroids: A Mortality Analysis of 26,508 Veterans Who Tested Positive for SARS-CoV-2. 
  • The Role of Vitamin D and Oxidative Stress in Chronic Kidney Disease. 
  • The Role of Vitamin D in CKD Stages 3 to 4: Report of a Scientific Workshop Sponsored by the National Kidney Foundation. 
  • The association between vitamin D and cardiometabolic risk factors in children: a systematic review. 
  • The association of serum vitamin D with incident diabetes in an African American population. 
  • The beehive and the merry-go-round in mineral metabolism. 
  • The effect of vitamin D supplementation on cardiovascular risk in patients with prediabetes: A secondary analysis of the D2d study. 
  • The severity of vasomotor symptoms and number of menopausal symptoms in postmenopausal women and select clinical health outcomes in the Women's Health Initiative Calcium and Vitamin D randomized clinical trial. 
  • The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation. 
  • To D or not to D: vitamin D in hematopoietic cell transplantation. 
  • Transcriptional components of anteroposterior positional information during zebrafish fin regeneration. 
  • Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations. 
  • Treating vitamin D deficiency in long-term care: it should be done yesterday, but how? 
  • Trends in Mineral Metabolism Treatment Strategies in Patients Receiving Hemodialysis in the United States. 
  • Two randomized vitamin D trials in ambulatory patients on anticonvulsants: impact on bone. 
  • Two randomized vitamin D trials in ambulatory patients on anticonvulsants: impact on bone. 
  • Uremic tumoral calcinosis: preliminary observations suggesting an association with aberrant vitamin D homeostasis. 
  • Very low levels of 25-hydroxyvitamin D are not associated with immunologic changes or clinical outcome in South African patients with HIV-associated cryptococcal meningitis. 
  • Vitamin D Levels and the Risk of Cognitive Decline in Chinese Elderly People: the Chinese Longitudinal Healthy Longevity Survey. 
  • Vitamin D Status Relates to Reproductive Outcome in Women With Polycystic Ovary Syndrome: Secondary Analysis of a Multicenter Randomized Controlled Trial. 
  • Vitamin D Stimulates Cardiomyocyte Proliferation and Controls Organ Size and Regeneration in Zebrafish. 
  • Vitamin D Supplementation and Prevention of Type 2 Diabetes. 
  • Vitamin D Supplementation for Prevention of Cancer: The D2d Cancer Outcomes (D2dCA) Ancillary Study. 
  • Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis. 
  • Vitamin D and cause-specific vascular disease and mortality: a Mendelian randomisation study involving 99,012 Chinese and 106,911 European adults. 
  • Vitamin D and prostate cancer survival in veterans. 
  • Vitamin D and the athlete-patient: state of the art. 
  • Vitamin D and uterine leiomyomata: Is it time to let the sunshine in? 
  • Vitamin D deficiency and anemia in early chronic kidney disease. 
  • Vitamin D deficiency exacerbates UV/endorphin and opioid addiction. 
  • Vitamin D deficiency in neovascular versus nonneovascular age-related macular degeneration. 
  • Vitamin D deficiency is not associated with changes in retinal geometric parameters in young people with type 1 diabetes. 
  • Vitamin D deficiency, inflammation, and albuminuria in chronic kidney disease: complex interactions. 
  • Vitamin D in patients with kidney disease: cautiously optimistic. 
  • Vitamin D in patients with renal failure: a summary of observational mortality studies and steps moving forward. 
  • Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase. 
  • Vitamin D insufficiency and cognitive impairment in Asians: a multi-ethnic population-based study and meta-analysis. 
  • Vitamin D insufficiency increases risk of chronic pain among African Americans experiencing motor vehicle collision. 
  • Vitamin D is Not Associated With Severity in NAFLD: Results of a Paired Clinical and Gene Expression Profile Analysis. 
  • Vitamin D levels and early mortality among incident hemodialysis patients. 
  • Vitamin D levels, dietary intake, and photoprotective behaviors among patients with skin cancer. 
  • Vitamin D status of black and white Americans and changes in vitamin D metabolites after varied doses of vitamin D supplementation. 
  • Vitamin D, Calcium, Magnesium, and Potassium Consumption and Markers of Glucose Metabolism in the Hispanic Community Health Study/Study of Latinos. 
  • Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. 
  • What you and your patients need to know about vitamin D. 
  • Zoledronic Acid in Reducing Clinical Fracture and Mortality after Hip Fracture. 
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  Keywords of People

  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics