Vitreous Body

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  Subject Areas on Research

  • A Nine-Year Analysis of Practice Patterns, Microbiologic Yield, and Clinical Outcomes in Cases of Presumed Infectious Endophthalmitis. 
  • A fiberoptic diathermy tissue manipulator for use in vitreous surgery. 
  • A method of imaging viscoelastic parameters with acoustic radiation force. 
  • A method to free retina and vitreous from intraoperative incarceration in the sclerotomy. 
  • A novel model of persistent retinal neovascularization for the development of sustained anti-VEGF therapies. 
  • A phase I study of intravitreal vascular endothelial growth factor trap-eye in patients with neovascular age-related macular degeneration. 
  • A prospective study of early intraocular pressure changes after a single intravitreal triamcinolone injection. 
  • A randomized trial comparing intravitreal triamcinolone and focal/grid photocoagulation for diabetic macular edema: baseline features. 
  • A sticky situation. 
  • ASTEROID HYALITIS: A STUDY OF SERUM CALCIUM LEVELS IN AFFECTED PATIENTS. 
  • Aclacinomycin A in the treatment of experimental proliferative vitreoretinopathy. Efficacy and toxicity in the rabbit eye. 
  • Acute intraocular inflammation after intravitreous injections of bevacizumab for treatment of neovascular age-related macular degeneration. 
  • Adverse events after intravitreal triamcinolone in patients with and without uveitis. 
  • Age-related changes in eye morphology and aqueous humor dynamics in DBA/2J mice using contrast-enhanced ocular MRI. 
  • Age-related changes in vitreous mobility as measured by video B scan ultrasound. 
  • Agreement between clinician and reading center gradings of diabetic retinopathy severity level at baseline in a phase 2 study of intravitreal bevacizumab for diabetic macular edema. 
  • Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis. 
  • An experimental model of preretinal neovascularization in the rabbit. 
  • An exploratory study of the safety, tolerability and bioactivity of a single intravitreal injection of vascular endothelial growth factor Trap-Eye in patients with diabetic macular oedema. 
  • An intravitreal device providing sustained release of cyclosporine and dexamethasone. 
  • An intravitreal sustained-release triamcinolone and 5-fluorouracil codrug in the treatment of experimental proliferative vitreoretinopathy. 
  • An outbreak of fungal endophthalmitis after intravitreal injection of compounded combined bevacizumab and triamcinolone. 
  • Analysis of pars plana vitrectomy for optic pit-related maculopathy with intraoperative optical coherence tomography: a possible connection with the vitreous cavity. 
  • Antifibrotic and uveitogenic properties of gamma interferon in the rabbit eye. 
  • Assays for the antiangiogenic and neurotrophic serpin pigment epithelium-derived factor. 
  • Association between anatomical resolution and functional outcomes in the mivi-trust studies using ocriplasmin to treat symptomatic vitreomacular adhesion/vitreomacular traction, including when associated with macular hole. 
  • Automated fluid-gas exchange. 
  • BASELINE CHARACTERISTICS OF VITREOMACULAR TRACTION PROGRESSING TO FULL-THICKNESS MACULAR OR LAMELLAR HOLES IN THE PHASE III TRIALS OF ENZYMATIC VITREOLYSIS. 
  • Bacterial contamination of needles used for intravitreal injections: a prospective, multicenter study. 
  • Biopsy of a Choroidal Melanoma Using Transvitreal Pars Plana Vitrectomy. 
  • CLINICAL CHARACTERISTICS AND VISUAL OUTCOMES IN ENDOPHTHALMITIS AFTER KERATOPROSTHESIS IMPLANTATION. 
  • Can chorio-retinal biopsy be justified? 
  • Cellular composition of post-haemorrhagic opacities in the human vitreous. 
  • Cellular senescence in the glaucomatous outflow pathway. 
  • Characterization of vitreoretinal interface disorders using OCT in the interventional phase 3 trials of ocriplasmin. 
  • Chorioretinal venous anastomosis for central retinal vein occlusion: transvitreal venipuncture. 
  • Chromosome 3 analysis of uveal melanoma using fine-needle aspiration biopsy at the time of plaque radiotherapy in 140 consecutive cases. 
  • Clearance of antitransferrin receptor immunotoxin from the rabbit eye. 
  • Clinicopathologic correlation of surgically removed macular hole opercula. 
  • Collagen shield delivery of tissue plasminogen activator: functional and pharmacokinetic studies of anterior segment delivery. 
  • Combined fluocinolone acetonide intravitreal insertion and glaucoma drainage device placement for chronic uveitis and glaucoma. 
  • Combined phacoemulsification and pars plana vitrectomy. 
  • Comparative studies of erythrophagocytosis in the rabbit and human vitreous. 
  • Comparison of flow cytometry with the surgeon regarding ability to predict the ultimate success of surgery for proliferative vitreoretinopathy. 
  • Cytokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy. 
  • Cytologic findings in vitreous fluids. Analysis of 74 specimens. 
  • Cytomegalovirus retinitis associated with Hodgkin's disease. 
  • Cytomegalovirus retinitis: a manifestation of the acquired immune deficiency syndrome (AIDS). 
  • Daunorubicin treatment in a refined experimental model of proliferative vitreoretinopathy. 
  • Delayed recalcitrant fungal endophthalmitis secondary to Curvularia. 
  • Demographic-related variations in posterior segment ocular sarcoidosis. 
  • Detection and quantification of S-100 protein in ocular tissues and fluids from patients with intraocular melanoma. 
  • Development and characterization of a vitreous mimicking material for radiation force imaging. 
  • Dexamethasone sustained drug delivery implant for the treatment of severe uveitis. 
  • Diagnosis and Treatment of Acute Retinal Necrosis: A Report by the American Academy of Ophthalmology. 
  • Diagnosis and management of opacified silicone intraocular lenses in patients with asteroid hyalosis. 
  • Diagnosis of vitreoretinal adhesions in macular disease with optical coherence tomography. 
  • Diagnostic yield of vitrectomy in eyes with suspected posterior segment infection or malignancy. 
  • Diagnostic yield of vitreous biopsy in presumed sarcoidosis-related posterior segment inflammation. 
  • Dispase facilitates posterior vitreous detachment during vitrectomy in young pigs. 
  • Dynamic Imaging of a Pigmented Free-Floating Vitreous Cyst. 
  • EPITHELIAL DOWNGROWTH IN THE VITREOUS CAVITY AND ON THE RETINA IN ENUCLEATED SPECIMENS AND IN EYES WITH VISUAL POTENTIAL. 
  • EVALUATION OF FULL-FIELD ELECTRORETINOGRAM REDUCTIONS AFTER OCRIPLASMIN TREATMENT: Results of the OASIS Trial ERG Substudy. 
  • Early rapid rise in intraocular pressure after intravitreal triamcinolone acetonide injection. 
  • Effect of the duration of macular edema on clinical outcomes in retinal vein occlusion treated with dexamethasone intravitreal implant. 
  • Effects of aging and environmental tobacco smoke exposure on ocular and plasma circulatory microRNAs in the Rhesus macaque. 
  • Effects of intravitreous injection of preserved and non-preserved triamcinolone in rabbit retina. 
  • Efficacy and safety of multiple intravitreal triamcinolone injections for refractory diabetic macular oedema. 
  • Efficacy of intravitreal ocriplasmin for treatment of vitreomacular adhesion: subgroup analyses from two randomized trials. 
  • Efficacy of low-release-rate fluocinolone acetonide intravitreal implants to treat experimental uveitis. 
  • Electron immunocytochemical analysis of posterior hyaloid associated with diabetic macular edema. 
  • Electron microscopic observations of intravitreal Cysticercus cellulosae (Taenia solium). 
  • Elevated levels of interleukin 6 in the vitreous fluid of patients with pars planitis and posterior uveitis: the Massachusetts eye & ear experience and review of previous studies. 
  • Endophthalmitis After Descemet Stripping Endothelial Keratoplasty: Microbiological Yield and Visual Outcomes. 
  • Endophthalmitis after penetrating trauma. Risk factors and visual acuity outcomes. 
  • Endophthalmitis: current approaches. 
  • Enhanced vitreous imaging in healthy eyes using swept source optical coherence tomography. 
  • Evaluation of a delivery system providing long-term release of cyclosporine. 
  • Experimental transvitreal cyanoacrylate retinopexy in a primate model. 
  • Experimental transvitreal cyanoacrylate retinopexy through silicone oil. 
  • Experimental transvitreal cyanoacrylate retinopexy. 
  • Eye pain after vitreoretinal surgery: a prospective study of 185 patients. 
  • Flow cytometry immunophenotyping of vitreous specimens does not contribute to diagnosis of lymphoma without supporting morphologic features. 
  • Fluocinolone acetonide sustained drug delivery device for chronic central retinal vein occlusion: 12-month results. 
  • Forming a Consensus: Data and Guidance for Physicians Treating Diabetic Macular Edema. 
  • Front and side fiberoptic illuminator for vitreous surgery. 
  • Histopathology of experimental preretinal neovascularization. 
  • Hyalocytes synthesize and secrete inhibitors of retinal pigment epithelial cell proliferation in vitro. 
  • Hyperreflective Vitreous Opacities on Optical Coherence Tomography in a Patient With Bilateral Retinoblastoma. 
  • Hypoxia precedes the development of experimental preretinal neovascularization. 
  • Impact of Total Pars Plana Vitrectomy on Postoperative Complications in Aphakic, Snap-On, Type 1 Boston Keratoprosthesis. 
  • Impact of cultures on management decisions following surgical repair of penetrating ocular trauma. 
  • Improvement in efficacy of corticosteroid therapy in an animal model of proliferative vitreoretinopathy by pretreatment. 
  • Increased incidence of sterile endophthalmitis after intravitreal triamcinolone acetonide in spring 2006. 
  • Increased nonenzymatically glycosylated proteins in the vitreous humor of diabetic animals. 
  • Infectious and Sterile Endophthalmitis in Eyes with Glaucoma Drainage Device from Two Large Ophthalmic Institutions. 
  • Influence of the Vitreomacular Interface on Treatment Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials. 
  • Interaction of retinal glial cells with collagen matrices: implications for pathogenesis of cell-mediated vitreous traction. 
  • Internal deformation of a uniform elastic solid by acoustic radiation force. 
  • Intraocular injection of recombinant hirudin to prevent experimental postoperative fibrin. 
  • Intraoperative ketorolac and eye pain after viteoretinal surgery: a prospective, randomized, placebo-controlled study. 
  • Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration: a short-term study. 
  • Intravitreal clearance of tissue plasminogen activator in the rabbit. 
  • Intravitreal foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome. 
  • Intravitreal injection of therapeutic agents. 
  • Intravitreal liposome-encapsulated drugs: a preliminary human report. 
  • Intravitreal sustained release corticosteroid-5-fluoruracil conjugate in the treatment of experimental proliferative vitreoretinopathy. 
  • Intravitreal sustained-release cyclosporine in the treatment of experimental uveitis. 
  • Intravitreal sustained-release dexamethasone device in the treatment of experimental uveitis. 
  • Intravitreal tissue plasminogen activator for the treatment of central retinal vein occlusion. 
  • Intravitreal triamcinolone acetonide for acute radiation papillopathy. 
  • Intravitreal triamcinolone acetonide for radiation maculopathy after plaque radiotherapy for choroidal melanoma. 
  • Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central retinal vein occlusion. 
  • Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central retinal vein occlusion. 
  • Intravitreal triamcinolone for cystoid macular edema related to branch retinal vein occlusion. 
  • LASIK and vitreous pathology after LASIK. 
  • LONGITUDINAL CHANGES IN THE OPTIC NERVE HEAD AND RETINA OVER TIME IN VERY YOUNG CHILDREN WITH FAMILIAL EXUDATIVE VITREORETINOPATHY. 
  • Large subretinal hemorrhage after intravitreal bevacizumab (Avastin) for age-related macular degeneration. 
  • Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis. 
  • Long-term results of successful vitrectomy with silicone oil for advanced proliferative vitreoretinopathy. 
  • Long-term retinal toxicity of intravitreal commercially available preserved triamcinolone acetonide (Kenalog) in rabbit eyes. 
  • Macular features from spectral-domain optical coherence tomography as an adjunct to indirect ophthalmoscopy in retinopathy of prematurity. 
  • Management of anterior vitreous traction in proliferative vitreoretinopathy. 
  • Management of intractable glaucoma following intravitreal triamcinolone acetonide. 
  • Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. 
  • Matrix metalloproteinases and their inhibitors in human vitreous. 
  • Measurement of cellular proliferation within the vitreous during experimental proliferative vitreoretinopathy. 
  • Metabolomics of Diabetic Retinopathy. 
  • Methicillin-Resistant Staphylococcus aureus Endogenous Endophthalmitis Retinal Detachment Repairs. 
  • Methods, statistical features, and baseline results of a standardized, multicentered ophthalmologic surgical trial: the Silicone Study. 
  • Minimizing the risk of endophthalmitis following intravitreal injections. 
  • Morphology of the fibrinogen exudate during evolution of a mycobacterial-induced murine eye granuloma. 
  • Mutational hot spot potential of a novel base pair mutation of the CSPG2 gene in a family with Wagner syndrome. 
  • Myopia predicts better outcome in persistent hyperplastic primary vitreous. 
  • N,N-dimethyladriamycin for treatment of experimental proliferative vitreoretinopathy: efficacy and toxicity on the rabbit retina. 
  • New scleral plugs for use during vitrectomy. 
  • Ocular component growth curves among Singaporean children with different refractive error status. 
  • Ocular penetration of 5-fluorocytosine. 
  • Ocular reticulum cell sarcoma. 
  • Ocular toxicity of daunomycin: effects of subdivided doses on the rabbit retina after vitreous gas compression. 
  • Optical coherence tomography to detect macular edema in the presence of asteroid hyalosis. 
  • Oxygen kinetics in preretinal perfluorotributylamine. 
  • Oxygen kinetics in the vitreous substitute perfluorotributylamine: a 19F NMR study in vivo. 
  • Pars plana vitrectomy, fluocinolone acetonide implantation, and silicone oil infusion for the treatment of chronic, refractory uveitic hypotony. 
  • Periocular triamcinolone for prevention of macular edema after iodine 125 plaque radiotherapy of uveal melanoma. 
  • Pharmacokinetics of the fluocinolone/5-fluorouracil codrug in the gas-filled eye. 
  • Pharmacokinetics of the ganciclovir implant in the silicone-filled eye. 
  • Pharmacologically defined components of the normal porcine multifocal ERG. 
  • Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1). 
  • Photodynamic therapy and intravitreal triamcinolone for extrafoveal choroidal neovascularization in neovascular age-related macular degeneration. 
  • Pneumatic Vitreolysis with Perfluoropropane for Vitreomacular Traction with and without Macular Hole: DRCR Retina Network Protocols AG and AH. 
  • Posterior internal ophthalmomyiasis. Identification of a surgically removed Cuterebra larva by scanning electron microscopy. 
  • Posttraumatic endophthalmitis due to CDC coryneform group A-3 bacteria. 
  • Preretinal and intraretinal exudates in familial exudative vitreoretinopathy. 
  • Pretreatment with intravitreal triamcinolone before laser for diabetic macular edema: 6-month results of a randomized, placebo-controlled trial. 
  • Prevention of experimental proliferative vitreoretinopathy with a biodegradable intravitreal implant for the sustained release of fluorouracil. 
  • Primary scleral buckling in open-globe injury involving the posterior segment. 
  • Progression of choroidal neovascularization following injection of pegaptanib sodium (macugen) in two eyes with neovascular age-related macular degeneration. 
  • Prospective study of a fluocinolone acetonide implant for chronic macular edema from central retinal vein occlusion: thirty-six-month results. 
  • Quantification of cellular proliferation in experimental proliferative vitreoretinopathy. 
  • Quantification of diabetic macular edema. 
  • Quantitative assessment of growth stimulating activity of the vitreous during PVR. 
  • Quantitative determination of the partial oxygen pressure in the vitrectomized rabbit eye in vivo using 19F NMR. 
  • Radiation force imaging of viscoelastic properties with reduced artifacts. 
  • Ranibizumab for treatment of neovascular age-related macular degeneration: a phase I/II multicenter, controlled, multidose study. 
  • Recombinant tissue plasminogen activator injected into the vitreous cavity may penetrate the retinal veins of a porcine model of vascular occlusion. 
  • Reduced Visual Acuity Following Kidney Stone Extraction. 
  • Refractive changes from use of silicone oil in vitreous surgery. 
  • Removal of intravitreous cysticerci from the surface of the optic nervehead. A pars plana approach. 
  • Results of peripheral laser photocoagulation in pars planitis. 
  • Results of silicone oil removal in advanced proliferative vitreoretinopathy. 
  • Retained Intraocular Perfluoro-n-octane After Valved Cannula Pars Plana Vitrectomy for Retinal Detachment. 
  • Retained perfluorodecalin after retinal detachment surgery. 
  • Retinal pigment epithelial tear with vitreomacular attachment: a novel pathogenic feature. 
  • Retinal vascular caliber changes after intravitreal triamcinolone treatment for diabetic macular edema. 
  • Reversible bull's-eye maculopathy associated with intravitreal fomivirsen therapy for cytomegalovirus retinitis. 
  • Rubeosis iridis: preoperative iris fluorescein angiography and periocular steroids. 
  • SCORE Study Report 7: incidence of intravitreal silicone oil droplets associated with staked-on vs luer cone syringe design. 
  • SCORE Study report 3: study design and baseline characteristics. 
  • Safety and pharmacokinetics of an intraocular fluocinolone acetonide sustained delivery device. 
  • Safety and pharmokinetics of triamcinolone hexacetonide in rabbit eyes. 
  • Schisis contributes to necrosis in experimental HSV-1 retinitis. 
  • Sensitivity of spiral computed tomography scanning for detecting intraocular foreign bodies. 
  • Silicone oil for progressive anterior ocular neovascularization after failed diabetic vitrectomy. 
  • Silicone oil for retinal detachment with advanced proliferative vitreoretinopathy following failed vitrectomy for proliferative diabetic retinopathy. 
  • Silicone oil in vitreoretinal surgery. Part 1: Surgical techniques. 
  • Silicone oil tamponade to seal macular holes without position restrictions. 
  • Six-week outcomes after pegaptanib. 
  • Spectral-Domain Optical Coherence Tomography of the Vitreopapillary Interface in Acute Nonarteritic Anterior Ischemic Optic Neuropathy. 
  • Sterile endophthalmitis after intravitreal triamcinolone: a possible association with uveitis. 
  • Streptococcal endophthalmitis in pediatric keratoprosthesis. 
  • Subfoveal Lucency after Treatment of Vitreomacular Traction without Macular Hole in the Phase 3 Trials of Ocriplasmin Vitreolysis. 
  • T cell activation within different intraocular compartments during experimental uveitis. 
  • The cell and molecular biology of glaucoma: mechanisms in the conventional outflow pathway. 
  • The effect of combined daunorubicin and triamcinolone acetonide treatment on a refined experimental model of proliferative vitreoretinopathy. 
  • The effect of intraocular irrigating solutions on lens clarity in normal and diabetic rabbits. 
  • The effect of intraocular pressure on the absorption of air from the vitreous cavity. 
  • The effects of intravitreal triamcinolone acetonide on experimental pre-retinal neovascularization. 
  • The effects of silicone oil removal. Silicone Study Report 6. 
  • The lack of toxicity of intravitreally administered triamcinolone acetonide. 
  • The pathology of vitreous hemorrhage. I. Gross and histological appearances. 
  • The pathology of vitreous hemorrhage. II. Ultrastructure. 
  • The role of vitrectomy instrumentation in the treatment of severe traumatic hyphema. 
  • The safety of intravitreal hyaluronidase. A clinical and histologic study. 
  • The significance of intraocular hemorrhages due to subarachnoid hemorrhage. 
  • The use of silicone oil following failed vitrectomy for retinal detachment with advanced proliferative vitreoretinopathy. 
  • The use of silicone oil following failed vitrectomy for retinal detachment with advanced proliferative vitreoretinopathy. 
  • Therapeutic effect of periocular corticosteroids in experimental proliferative vitreoretinopathy. 
  • Time to Presentation after Symptom Onset in Endophthalmitis: Clinical Features and Visual Outcomes. 
  • Tissue plasminogen activator for postvitrectomy fibrin formation. 
  • Transvitreal cyanoacrylate retinopexy in the management of complicated retinal detachment. 
  • Transvitreal cyanoacrylate retinopexy in the management of complicated retinal detachment. 
  • Treatment of neovascular age-related macular degeneration with intravitreal bevacizumab: efficacy of three consecutive monthly injections. 
  • Treatment of posterior uveitis with a fluocinolone acetonide implant: three-year clinical trial results. 
  • Treatment of postvitrectomy fibrin pupillary block with tissue plasminogen activator. 
  • Triamcinolone-induced cataract in eyes with diabetic macular oedema: 3-year prospective data from a randomized clinical trial. 
  • Tug of war. 
  • Ultrastructure and clinicopathologic correlation of idiopathic preretinal macular fibrosis. 
  • Use of the polymerase chain reaction for diagnosis of ocular toxoplasmosis. 
  • Vitrectomy for diabetic macular edema. 
  • Vitrectomy for the diagnosis and management of uveitis of unknown cause. 
  • Vitrectomy for vitreomacular traction syndrome with macular detachment. 
  • Vitrectomy prevents retinal hypoxia in branch retinal vein occlusion. 
  • Vitrectomy update for macular traction in ocular toxocariasis. 
  • Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy. Silicone Study Report 3. 
  • Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 2. 
  • Vitrectomy with silicone oil or sulfur hexafluoride gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 1. 
  • Vitreous hemorrhage after intracranial hemorrhage. 
  • Vitreous hemorrhage associated with sickle-cell trait and sickle-cell hemoglobin-C disease. 
  • Vitreous membrane formation after experimental vitreous haemorrhage. 
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  Keywords of People

  • Farsiu, Sina, Professor in the Department of Biomedical Engineering, Electrical and Computer Engineering
  • Fekrat, Sharon, Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Toth, Cynthia Ann, Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology, Biomedical Engineering