von Willebrand Diseases

• 

  Subject Areas on Research

  • A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11. 
  • Acquired von Willebrand syndrome in continuous-flow ventricular assist device recipients. 
  • Assessment of primary hemostasis by PFA-100 analysis in a tertiary care center. 
  • Bleeding disorders in premenopausal women: (another) public health crisis for hematology? 
  • Bleeding events and other complications during pregnancy and childbirth in women with von Willebrand disease. 
  • Characterization of Leu777Pro and Ile865Thr type IIA von Willebrand disease mutations. 
  • Clinical and laboratory diagnosis of von Willebrand disease: a synopsis of the 2008 NHLBI/NIH guidelines. 
  • Comparative analysis of type 2b von Willebrand disease mutations: implications for the mechanism of von Willebrand factor binding to platelets. 
  • Complications of hysterectomy in women with von Willebrand disease. 
  • Congenital platelet disorder and type I von Willebrand disease presenting as prolonged bleeding after cleft lip and palate repair. 
  • Contemporary issues in the management of von Willebrand disease. 
  • Crucial role for the VWF A1 domain in binding to type IV collagen. 
  • Diagnosis and management of inherited von Willebrand disease in the next decade: panel discussion. 
  • Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin. 
  • Evidence that calpains and elastase do not produce the von Willebrand factor fragments present in normal plasma and IIA von Willebrand disease. 
  • Feasibility of the Von Willebrand disease PREVENT trial. 
  • Functional analysis of a type IIB von Willebrand disease missense mutation: increased binding of large von Willebrand factor multimers to platelets. 
  • Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor. 
  • Management of a patient with type IIC von Willebrand's disease during coronary artery bypass graft surgery. 
  • Management of epistaxis in patients with ventricular assist device: a retrospective review. 
  • Mechanisms of bleeding and approach to patients with axial-flow left ventricular assist devices. 
  • Molecular pathogenesis and heterogeneity in type 3 VWD families in U.S. Zimmerman program. 
  • More than menorrhagia: a review of the obstetric and gynaecological manifestations of von Willebrand disease. 
  • Obstetric management of adolescents with bleeding disorders. 
  • Postpartum von Willebrand factor levels in women with and without von Willebrand disease and implications for prophylaxis. 
  • Proteolytic degradation of von Willebrand factor after DDAVP administration in normal individuals. 
  • Pseudo-von Willebrand disease: a mutation in the platelet glycoprotein Ib alpha gene associated with a hyperactive surface receptor. 
  • Report on the workshop on Hereditary Hemorrhagic Telangiectasia, July 10-11, 1997. 
  • State of the art: von Willebrand disease. 
  • Testing for von Willebrand disease in women with menorrhagia: a systematic review. 
  • The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domain. 
  • The role of haemophilia treatment centres in providing services to women with bleeding disorders. 
  • Use of 1-desamino-8-D-arginine vasopressin in microsurgical reconstruction in a patient with von Willebrand's disease. 
  • Use of a new platelet function analyzer to detect von Willebrand disease in women with menorrhagia. 
  • Use of the levonorgestrel-releasing intrauterine system in women with hemostatic disorders. 
  • Von Willebrand Disease, Hemophilia, and Other Inherited Bleeding Disorders in Pregnancy. 
  • Von Willebrand disease and other bleeding disorders in women: consensus on diagnosis and management from an international expert panel. 
  • Von Willebrand disease in women: awareness and diagnosis. 
  • Von Willebrand disease. 
  • Von Willebrand disease: key points from the 2008 National Heart, Lung, and Blood Institute guidelines. 
  • Von Willebrand factor for menorrhagia: a survey and literature review. 
  • Warfarin and Aspirin Versus Warfarin Alone for Prevention of Embolic Events in Patients with a HeartMate II Left Ventricular Assist Device. 
  • Women and bleeding disorders. 
  • von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA). 
  • von Willebrand disease in the 21st century: current approaches and new challenges. 
  • von Willebrand disease in the RIIIS/J mouse is caused by a defect outside of the von Willebrand factor gene. 
  • von Willebrand's disease diagnosed after menorrhagia worsened from levonorgestrel intrauterine system. 
• 

  Keywords of People

  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology