Y Chromosome

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  Subject Areas on Research

  • A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. 
  • A microarray analysis of the XX Wnt4 mutant gonad targeted at the identification of genes involved in testis vascular differentiation. 
  • A new resource for characterizing X-linked genes in Drosophila melanogaster: systematic coverage and subdivision of the X chromosome with nested, Y-linked duplications. 
  • A physical map of the human Y chromosome. 
  • Abundant gene conversion between arms of palindromes in human and ape Y chromosomes. 
  • Anti-receptor antibody-induced suppression of murine H-Y-specific delayed-type hypersensitivity responses. 
  • Cellular and molecular pathways regulating mammalian sex determination. 
  • Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content. 
  • Chromosome manipulation: a systematic approach toward understanding human chromosome structure and function. 
  • Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee. 
  • Constitutive magnification by the Ybb- chromosome of Drosophila melanogaster. 
  • Deletion of Y chromosome sequences located outside the testis determining region can cause XY female sex reversal. 
  • Deletion of azoospermia factor a (AZFa) region of human Y chromosome caused by recombination between HERV15 proviruses. 
  • Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis. 
  • Development. The minimalist Y. 
  • Differential replication of ribosomal gene repeats in polytene nuclei of Drosophila. 
  • Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad. 
  • Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. 
  • Efficient random subcloning of DNA sheared in a recirculating point-sink flow system. 
  • Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal. 
  • Ethylenecarbodiimide-treated splenocytes carrying male CD4 epitopes confer histocompatibility Y chromosome antigen transplant protection by inhibiting CD154 upregulation. 
  • Evolution of fungal sex chromosomes. 
  • Has the chimpanzee Y chromosome been sequenced? 
  • How Big Is Your Y? A Genome-Sequence Based Estimate of the Size of the Male-Specific Region in Megaselia scalaris 
  • Incomplete Y chromosomes promote magnification in male and female Drosophila. 
  • Magnification of the ribosomal genes in female Drosophila melanogaster. 
  • Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators. 
  • Mapping of sex determination loci on the white campion (Silene latifolia) Y chromosome using amplified fragment length polymorphism. 
  • Mesonephric cell migration induces testis cord formation and Sertoli cell differentiation in the mammalian gonad. 
  • Microsatellites provide evidence for Y chromosome diversity among the founders of the New World. 
  • Migration of mesonephric cells into the mammalian gonad depends on Sry. 
  • Molecular characterization of ribosomal genes on the Ybb- chromosome of Drosophila melanogaster. 
  • Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization. 
  • One tissue, two fates: molecular genetic events that underlie testis versus ovary development. 
  • Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad. 
  • Peritubular myoid cells are not the migrating population required for testis cord formation in the XY gonad. 
  • Polytenization of the ribosomal genes on the X and Y chromosomes of Drosophila melanogaster. 
  • Recombination between palindromes P5 and P1 on the human Y chromosome causes massive deletions and spermatogenic failure. 
  • Recruitment of host progenitor cells in rat liver transplants. 
  • Recruitment of marrow-derived endothelial cells to experimental choroidal neovascularization by local expression of vascular endothelial growth factor. 
  • Refined mapping and YAC contig construction of the X-linked cleft palate and ankyloglossia locus (CPX) including the proximal X-Y homology breakpoint within Xq21.3. 
  • Sequencing the mouse Y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes. 
  • Sex and the circuitry: progress toward a systems-level understanding of vertebrate sex determination. 
  • Sex in the 90s: SRY and the switch to the male pathway. 
  • Sry induces cell proliferation in the mouse gonad. 
  • Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes. 
  • The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men. 
  • The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned. 
  • The battle of the sexes: opposing pathways in sex determination. 
  • The generation of extracellular DNA in SLE: the role of death and sex. 
  • The influence of Yaa on anti-DNA responses of B6-lpr mice. 
  • Translocation of Y-linked genes to the dot chromosome in Drosophila pseudoobscura. 
  • Y chromosomes traveling south: the cohen modal haplotype and the origins of the Lemba--the "Black Jews of Southern Africa". 
  • Y353/B: a candidate multiple-copy spermiogenesis gene on the mouse Y chromosome.