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Subject Areas on Research
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A Genetic Cardiomyocyte Ablation Model for the Study of Heart Regeneration in Zebrafish.
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A Roadmap to Heart Regeneration Through Conserved Mechanisms in Zebrafish and Mammals.
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A Wnt-CKIvarepsilon-Rap1 pathway regulates gastrulation by modulating SIPA1L1, a Rap GTPase activating protein.
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A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations.
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A bioenergetics assay for studying the effects of environmental stressors on mitochondrial function in vivo in zebrafish larvae.
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A classification system for zebrafish adipose tissues.
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A conserved role of αA-crystallin in the development of the zebrafish embryonic lens.
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A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome.
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A dual role for ErbB2 signaling in cardiac trabeculation.
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A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration.
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A non-canonical type 2 immune response coordinates tuberculous granuloma formation and epithelialization.
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A novel alternative splice domain in zebrafish tenascin-C.
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A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development.
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A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS.
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A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development.
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A novel ribosomopathy caused by dysfunction of RPL10 disrupts neurodevelopment and causes X-linked microcephaly in humans.
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A robust and flexible CRISPR/Cas9-based system for neutrophil-specific gene inactivation in zebrafish.
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A tale of two species: Neural integration in zebrafish and monkeys.
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A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation.
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A zebrafish model for the Shwachman-Diamond syndrome (SDS).
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A zebrafish model of germ cell aneuploidy.
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AHR2 knockdown prevents PAH-mediated cardiac toxicity and XRE- and ARE-associated gene induction in zebrafish (Danio rerio).
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AHR2 morpholino knockdown reduces the toxicity of total particulate matter to zebrafish embryos.
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AHR2-Mediated transcriptomic responses underlying the synergistic cardiac developmental toxicity of PAHs.
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Acoustofluidic rotational tweezing enables high-speed contactless morphological phenotyping of zebrafish larvae.
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Acute Exposure to Permethrin Modulates Behavioral Functions, Redox, and Bioenergetics Parameters and Induces DNA Damage and Cell Death in Larval Zebrafish.
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Acute administration of dopaminergic drugs has differential effects on locomotion in larval zebrafish.
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Acute and developmental behavioral effects of flame retardants and related chemicals in zebrafish.
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Acute neuroactive drug exposures alter locomotor activity in larval zebrafish.
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Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish.
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Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation.
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Agrin is required for posterior development and motor axon outgrowth and branching in embryonic zebrafish.
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An ancestral mycobacterial effector promotes dissemination of infection.
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An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair.
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An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection.
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An explant technique for high-resolution imaging and manipulation of mycobacterial granulomas.
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An injury-responsive gata4 program shapes the zebrafish cardiac ventricle.
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Angiopellosis as an Alternative Mechanism of Cell Extravasation.
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Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease.
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Animal models of hereditary iron transport disorders.
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Antioxidant Rescue of Selenomethionine-Induced Teratogenesis in Zebrafish Embryos.
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Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish.
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Anxiolytic effects of nicotine in zebrafish.
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Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor.
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Assessing locomotor activity in larval zebrafish: Influence of extrinsic and intrinsic variables.
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BDE 49 and developmental toxicity in zebrafish.
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BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning.
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Back in Black.
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Best practices for germ-free derivation and gnotobiotic zebrafish husbandry.
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Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway.
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Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes.
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Biallelic SQSTM1 mutations in early-onset, variably progressive neurodegeneration.
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Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2.
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Biotic and abiotic interactions in aquatic microcosms determine fate and toxicity of Ag nanoparticles: part 2-toxicity and Ag speciation.
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Bleb Expansion in Migrating Cells Depends on Supply of Membrane from Cell Surface Invaginations.
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Bmp and Fgf signaling are essential for liver specification in zebrafish.
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Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion.
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Brief embryonic strychnine exposure in zebrafish causes long-term adult behavioral impairment with indications of embryonic synaptic changes.
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Building and re-building the heart by cardiomyocyte proliferation.
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Building bridges, not walls: spinal cord regeneration in zebrafish.
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Buspirone, chlordiazepoxide and diazepam effects in a zebrafish model of anxiety.
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C/EBPβ controls exercise-induced cardiac growth and protects against pathological cardiac remodeling.
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CERKL gene knockout disturbs photoreceptor outer segment phagocytosis and causes rod-cone dystrophy in zebrafish.
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CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis.
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CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections.
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COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness.
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CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation.
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CYP1B1 knockdown does not alter synergistic developmental toxicity of polycyclic aromatic hydrocarbons in zebrafish (Danio rerio).
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Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative study.
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Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development.
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Calcium signaling regulates ventricular hypertrophy during development independent of contraction or blood flow.
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Ccn2a is an injury-induced matricellular factor that promotes cardiac regeneration in zebrafish.
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Cellular projections from sensory hair cells form polarity-specific scaffolds during synaptogenesis.
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Cerium oxide nanoparticles are more toxic than equimolar bulk cerium oxide in Caenorhabditis elegans.
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Cftr controls lumen expansion and function of Kupffer's vesicle in zebrafish.
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Changes in gravitational force induce alterations in gene expression that can be monitored in the live, developing zebrafish heart.
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Characterizing sources of variability in zebrafish embryo screening protocols.
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Chlorpyrifos exposure of developing zebrafish: effects on survival and long-term effects on response latency and spatial discrimination.
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Cilia proteins are biomarkers of altered flow in the vasculature.
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Ciliogenesis mechanisms mediated by PAK2-ARL13B signaling in brain endothelial cells is responsible for vascular stability.
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Clonally dominant cardiomyocytes direct heart morphogenesis.
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Cloning of zebrafish vsx1: expression of a paired-like homeobox gene during CNS development.
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Commensal Bacteria Regulate Gene Expression and Differentiation in Vertebrate Olfactory Systems Through Transcription Factor REST.
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Commensal Microbiota Regulate Vertebrate Innate Immunity-Insights From the Zebrafish.
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Commensal microbiota stimulate systemic neutrophil migration through induction of serum amyloid A.
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Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor.
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Comparative pathogenesis of Mycobacterium marinum and Mycobacterium tuberculosis.
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Computational 3D histological phenotyping of whole zebrafish by X-ray histotomography.
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Connectomics of the zebrafish's lateral-line neuromast reveals wiring and miswiring in a simple microcircuit.
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Conserved anti-inflammatory effects and sensing of butyrate in zebrafish.
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Conserved roles for Hnf4 family transcription factors in zebrafish development and intestinal function.
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Construction and detection of fluorescent, germline transgenic zebrafish.
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Construction of a zebrafish cDNA microarray: gene expression profiling of the zebrafish during development.
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Contribution of neutral processes to the assembly of gut microbial communities in the zebrafish over host development.
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Control of osteoblast regeneration by a train of Erk activity waves.
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Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3.
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Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation.
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Correcting for physical distortions in visual stimuli improves reproducibility in zebrafish neuroscience.
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Coupled mutagenesis screens and genetic mapping in zebrafish.
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Critical duration of exposure for developmental chlorpyrifos-induced neurobehavioral toxicity.
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Cse1l is a negative regulator of CFTR-dependent fluid secretion.
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Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling.
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DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.
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De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome.
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Deep phenotyping in zebrafish reveals genetic and diet-induced adiposity changes that may inform disease risk.
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Defining drinking water metal contaminant mixture risk by coupling zebrafish behavioral analysis with citizen science.
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Deletion of the transmembrane protein Prom1b in zebrafish disrupts outer-segment morphogenesis and causes photoreceptor degeneration.
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Detection of autofluorescent Mycobacterium chelonae in living zebrafish.
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Development of a quantitative morphological assessment of toxicant-treated zebrafish larvae using brightfield imaging and high-content analysis.
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Developmental Exposure to Low Concentrations of Organophosphate Flame Retardants Causes Life-Long Behavioral Alterations in Zebrafish.
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Developmental chlorpyrifos effects on hatchling zebrafish swimming behavior.
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Developmental exposure of zebrafish to neonicotinoid pesticides: Long-term effects on neurobehavioral function.
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Developmental exposure of zebrafish to vitamin D receptor acting drugs and environmental toxicants disrupts behavioral function.
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Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio).
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Developmental exposure to an organophosphate flame retardant alters later behavioral responses to dopamine antagonism in zebrafish larvae.
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Developmental exposure to low concentrations of two brominated flame retardants, BDE-47 and BDE-99, causes life-long behavioral alterations in zebrafish.
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Developmental exposure to organophosphate flame retardants causes behavioral effects in larval and adult zebrafish.
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Developmental exposure to organophosphate flame retardants elicits overt toxicity and alters behavior in early life stage zebrafish (Danio rerio).
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Developmental exposure to the flame retardant, triphenyl phosphate, causes long-lasting neurobehavioral and neurochemical dysfunction.
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Developmental exposure to valproate and ethanol alters locomotor activity and retino-tectal projection area in zebrafish embryos.
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Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs.
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Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β.
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Developmentally regulated expression of two members of the Nrarp family in zebrafish.
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Differential acetylcholinesterase inhibition of chlorpyrifos, diazinon and parathion in larval zebrafish.
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Differential recruitment of co-regulatory proteins to the human estrogen receptor 1 in response to xenoestrogens.
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Direct In Vivo Manipulation and Imaging of Calcium Transients in Neutrophils Identify a Critical Role for Leading-Edge Calcium Flux.
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Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer.
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Discovery and ramifications of incidental Magnéli phase generation and release from industrial coal-burning.
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Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos.
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Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration.
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Distinct roles for luminal acidification in apical protein sorting and trafficking in zebrafish.
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Dopamine D1 and D2 receptor antagonism during development alters later behavior in zebrafish.
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Drug-Induced Liver Injury.
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Drug-Inducible, Cell-Specific Manipulation of Intracellular Calcium in Zebrafish Through Mammalian TRPV1 Expression.
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Dual Molecular Effects of Dominant RORA Mutations Cause Two Variants of Syndromic Intellectual Disability with Either Autism or Cerebellar Ataxia.
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Dwarfism and increased adiposity in the gh1 mutant zebrafish vizzini.
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Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway.
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Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity.
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Early zebrafish embryogenesis is susceptible to developmental TDCPP exposure.
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Early-onset stroke and vasculopathy associated with mutations in ADA2.
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Effect-directed analysis of Elizabeth River porewater: developmental toxicity in zebrafish (Danio rerio).
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Effects of sub-chronic methylphenidate on risk-taking and sociability in zebrafish (Danio rerio).
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Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.
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Elucidating the role of plexin D1 in body fat distribution and susceptibility to metabolic disease using a zebrafish model system.
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Embryonic exposure to PFAS causes long-term, compound-specific behavioral alterations in zebrafish.
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Embryonic exposure to benzo[a]pyrene causes age-dependent behavioral alterations and long-term metabolic dysfunction in zebrafish.
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Embryonic expression and steroid regulation of brain aromatase cyp19a1b in zebrafish (Danio rerio).
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Embryonic expression of zebrafish MiT family genes tfe3b, tfeb, and tfec.
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Endogenous Tagging at the cdh1 Locus for Live Visualization of E-Cadherin Dynamics.
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Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis.
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Enhancer selection dictates gene expression responses in remote organs during tissue regeneration.
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Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways.
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Epicardial regeneration is guided by cardiac outflow tract and Hedgehog signalling.
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Epigenetic control of intestinal barrier function and inflammation in zebrafish.
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Epithelial delamination is protective during pharmaceutical-induced enteropathy.
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Evaluating the zebrafish embryo toxicity test for pesticide hazard screening.
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Evidence for a core gut microbiota in the zebrafish.
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Expanding allelic and phenotypic spectrum of ZC4H2-related disorder: A novel hypomorphic variant and high prevalence of tethered cord.
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Explant culture of adult zebrafish hearts for epicardial regeneration studies.
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Exposure to 1,2-Propanediol Impacts Early Development of Zebrafish (Danio rerio) and Induces Hyperactivity.
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Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development.
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Expression of cyp26b1 during zebrafish early development.
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Expression of fgf23 and αklotho in developing embryonic tissues and adult kidney of the zebrafish, Danio rerio.
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Extended haplotype-phasing of long-read de novo genome assemblies using Hi-C.
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Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis.
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FGF signaling regulates rod photoreceptor cell maintenance and regeneration in zebrafish.
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Feedback mechanisms regulate retinoic acid production and degradation in the zebrafish embryo.
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Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration.
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Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish.
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Fgfs control homeostatic regeneration in adult zebrafish fins.
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Fibronectin is deposited by injury-activated epicardial cells and is necessary for zebrafish heart regeneration.
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First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass.
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Fit for consumption: zebrafish as a model for tuberculosis.
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Flow Cytometry for the Immunotoxicologist.
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Fluoranthene, but not benzo[a]pyrene, interacts with hypoxia resulting in pericardial effusion and lordosis in developing zebrafish.
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From Whole-Brain Data to Functional Circuit Models: The Zebrafish Optomotor Response.
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From man to fish: What can Zebrafish tell us about ApoL1 nephropathy?
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Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder.
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Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine.
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G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.
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GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish.
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Gene expression changes in developing zebrafish as potential markers for rapid developmental neurotoxicity screening.
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Generation of specialized blood vessels via lymphatic transdifferentiation.
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Genetic Reprogramming of Positional Memory in a Regenerating Appendage.
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Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.
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Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions.
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Genetic control of single lumen formation in the zebrafish gut.
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Genome-wide association and functional follow-up reveals new loci for kidney function.
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Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells.
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Genomic sequencing-based mutational enrichment analysis identifies motility genes in a genetically intractable gut microbe.
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Genomic structure and embryonic expression of estrogen receptor beta a (ERbetaa) in zebrafish (Danio rerio).
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Germ cell aneuploidy in zebrafish with mutations in the mitotic checkpoint gene mps1.
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Getting the inside tract: new frontiers in zebrafish digestive system biology.
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Getting to the heart of regeneration in zebrafish.
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Gigapixel imaging with a novel multi-camera array microscope.
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Glafenine-induced intestinal injury in zebrafish is ameliorated by μ-opioid signaling via enhancement of Atf6-dependent cellular stress responses.
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Glutathione and zebrafish: Old assays to address a current issue.
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Glutathione transferase pi class 2 (GSTp2) protects against the cardiac deformities caused by exposure to PAHs but not PCB-126 in zebrafish embryos.
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Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota.
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Halogenated carbazoles induce cardiotoxicity in developing zebrafish (Danio rerio) embryos.
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Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration.
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Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish.
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Haploinsufficiency of the Sin3/HDAC corepressor complex member SIN3B causes a syndromic intellectual disability/autism spectrum disorder.
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Heart regeneration in zebrafish.
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High fat diet induces microbiota-dependent silencing of enteroendocrine cells.
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High-Throughput Tissue Bioenergetics Analysis Reveals Identical Metabolic Allometric Scaling for Teleost Hearts and Whole Organisms.
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High-Throughput Video Processing of Heart Rate Responses in Multiple Wild-type Embryonic Zebrafish per Imaging Field.
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Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections.
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Host-microbe interactions in the developing zebrafish.
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How the zebrafish gets its stripes.
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Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish.
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Identification and characterization of a functional zebrafish smrt corepressor (ncor2).
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Identification and requirements of enhancers that direct gene expression during zebrafish fin regeneration.
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Identification of enhancer regulatory elements that direct epicardial gene expression during zebrafish heart regeneration.
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Identification of nonvisual photomotor response cells in the vertebrate hindbrain.
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Imaging and Isolation of Extravasation-Participating Endothelial and Melanoma Cells During Angiopellosis.
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Immediate and long-term consequences of vascular toxicity during zebrafish development.
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In Toto Imaging of Dynamic Osteoblast Behaviors in Regenerating Skeletal Bone.
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In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress.
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In vivo analysis of white adipose tissue in zebrafish.
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In vivo imaging and genetic analysis link bacterial motility and symbiosis in the zebrafish gut.
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In vivo imaging and quantification of regional adiposity in zebrafish.
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In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma.
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In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration.
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In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration.
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Increased coiling frequency linked to apoptosis in the brain and altered thyroid signaling in zebrafish embryos (Danio rerio) exposed to the PBDE metabolite 6-OH-BDE-47.
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Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration.
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Induction of lef1 during zebrafish fin regeneration.
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Infection-Induced Vascular Permeability Aids Mycobacterial Growth.
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Infectious disease models in zebrafish.
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Inhibition of infection-induced vascular permeability modulates host leukocyte recruitment to Mycobacterium marinum granulomas in zebrafish.
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Injury-induced ctgfa directs glial bridging and spinal cord regeneration in zebrafish.
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Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation.
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Integrating light-sheet imaging with virtual reality to recapitulate developmental cardiac mechanics
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Interception of host angiogenic signalling limits mycobacterial growth.
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Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.
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Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization.
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Introduction to zebrafish: current discoveries and emerging technologies for neurobehavioral toxicology and teratology.
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Intronic cis-regulatory modules mediate tissue-specific and microbial control of angptl4/fiaf transcription.
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Investigating the importance of anatomical homology for cross-species phenotype comparisons using semantic similarity. - Accepted at pacific symposium on biocomputing, 2016
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Knock-in tagging in zebrafish facilitated by insertion into non-coding regions.
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Knockdown of AHR1A but not AHR1B exacerbates PAH and PCB-126 toxicity in zebrafish (Danio rerio) embryos.
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Knocking out lca5 in zebrafish causes cone-rod dystrophy due to impaired outer segment protein trafficking.
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Knockout of Nr2e3 prevents rod photoreceptor differentiation and leads to selective L-/M-cone photoreceptor degeneration in zebrafish.
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L-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome.
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Laser-scanning velocimetry: a confocal microscopy method for quantitative measurement of cardiovascular performance in zebrafish embryos and larvae.
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Learning: Plasticity without Stabilization in Olfactory Cortex.
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Less is more: compact genomes pay dividends.
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Ligament versus bone cell identity in the zebrafish hyoid skeleton is regulated by mef2ca.
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Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion.
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Live Imaging of Host-Pathogen Interactions in Zebrafish Larvae.
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Live Monitoring of Blastemal Cell Contributions during Appendage Regeneration.
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Live fate-mapping of joint-associated fibroblasts visualizes expansion of cell contributions during zebrafish fin regeneration.
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Local Dkk1 crosstalk from breeding ornaments impedes regeneration of injured male zebrafish fins.
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Locomotion in larval zebrafish: Influence of time of day, lighting and ethanol.
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Long-term behavioral impairment following acute embryonic ethanol exposure in zebrafish.
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Loss of cftr function leads to pancreatic destruction in larval zebrafish.
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Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations.
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Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration.
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Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut.
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MNK2 deficiency potentiates β-cell regeneration via translational regulation.
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Macrophage ACKRobatics: An atypical Cxcr3 keeps macrophages in check.
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Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection.
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Macrophage NFATC2 mediates angiogenic signaling during mycobacterial infection.
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Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins.
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Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species.
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Maternal transfer of nanoplastics to offspring in zebrafish (Danio rerio): A case study with nanopolystyrene.
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Mathematical modeling of Erk activity waves in regenerating zebrafish scales.
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Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight.
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Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation.
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Meeting report: high-throughput technologies for in vivo imaging agents.
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Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits.
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Methodologies for Inducing Cardiac Injury and Assaying Regeneration in Adult Zebrafish.
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Methods for generating and colonizing gnotobiotic zebrafish.
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Microarray gene expression profiling during the segmentation phase of zebrafish development.
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Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract.
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Microbial colonization is required for normal neurobehavioral development in zebrafish.
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Microbiota regulate intestinal absorption and metabolism of fatty acids in the zebrafish.
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Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha.
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Microgavage of zebrafish larvae.
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Mitochondria as a target of organophosphate and carbamate pesticides: Revisiting common mechanisms of action with new approach methodologies.
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Mitochondrial response and resilience to anthropogenic chemicals during embryonic development.
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Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research.
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Modulation of tissue repair by regeneration enhancer elements.
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Monitoring neural activity with bioluminescence during natural behavior.
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Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration.
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Mucosal candidiasis elicits NF-κB activation, proinflammatory gene expression and localized neutrophilia in zebrafish.
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Multicolor Cell Barcoding Technology for Long-Term Surveillance of Epithelial Regeneration in Zebrafish.
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Multicolor mapping of the cardiomyocyte proliferation dynamics that construct the atrium.
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Mutational analysis of endothelin receptor b1 (rose) during neural crest and pigment pattern development in the zebrafish Danio rerio.
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Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy.
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Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination.
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Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies.
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Mutations in fam20b and xylt1 reveal that cartilage matrix controls timing of endochondral ossification by inhibiting chondrocyte maturation.
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Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS.
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Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids.
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Myocardial NF-κB activation is essential for zebrafish heart regeneration.
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Myocardium and BMP signaling are required for endocardial differentiation.
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Nanoplastics Decrease the Toxicity of a Complex PAH Mixture but Impair Mitochondrial Energy Production in Developing Zebrafish.
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Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration.
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Neural Circuits Underlying Visually Evoked Escapes in Larval Zebrafish.
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Neural circuits. Labeling of active neural circuits in vivo with designed calcium integrators.
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Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact?
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Neurobehavioral effects of 1,2-propanediol in zebrafish (Danio rerio).
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Neurobehavioral impairments caused by developmental imidacloprid exposure in zebrafish.
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Neuronal regulation of the spatial patterning of neurogenesis.
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Neurotoxicity of FireMaster 550® in zebrafish (Danio rerio): Chronic developmental and acute adolescent exposures.
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Neutrons do not produce a bystander effect in zebrafish irradiated in vivo.
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New regulators of vertebrate appendage regeneration.
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Newspapers and newspaper ink contain agonists for the ah receptor.
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Nicotine effects on learning in zebrafish: the role of dopaminergic systems.
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Nicotinic involvement in memory function in zebrafish.
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Notochord vacuoles absorb compressive bone growth during zebrafish spine formation.
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Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis.
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Notochordal Signals Establish Phylogenetic Identity of the Teleost Spine.
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Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish.
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Nuclear phosphatase PPM1G in cellular survival and neural development.
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Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion.
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Ontogenetic Differences in Dietary Fat Influence Microbiota Assembly in the Zebrafish Gut.
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Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio).
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Origin, Specification, and Plasticity of the Great Vessels of the Heart.
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Otx but not Mitf transcription factors are required for zebrafish retinal pigment epithelium development.
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Outcomes of developmental exposure to total particulate matter from cigarette smoke in zebrafish (Danio rerio).
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PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia.
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PCR-Based Determination of Mitochondrial DNA Copy Number in Multiple Species.
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Persistent behavioral effects following early life exposure to retinoic acid or valproic acid in zebrafish.
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Persistent behavioral impairment caused by embryonic methylphenidate exposure in zebrafish.
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Persisting effects of a PBDE metabolite, 6-OH-BDE-47, on larval and juvenile zebrafish swimming behavior.
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Perspectives on zebrafish neurobehavioral pharmacology.
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Pharmacological analyses of learning and memory in zebrafish (Danio rerio).
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Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2.
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Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathway.
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Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue.
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Polycyclic aromatic hydrocarbon and hypoxia exposures result in mitochondrial dysfunction in zebrafish.
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Positional cloning of a temperature-sensitive mutant emmental reveals a role for sly1 during cell proliferation in zebrafish fin regeneration.
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Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.
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Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.
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Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi.
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Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection.
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Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes.
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Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models.
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Quantitative label-free phosphoproteomics strategy for multifaceted experimental designs.
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RNA sequencing of isolated cell populations expressing human APOL1 G2 risk variant reveals molecular correlates of sickle cell nephropathy in zebrafish podocytes.
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ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm.
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RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro.
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Radial migration: Retinal neurons hold on for the ride.
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Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish.
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Rapid, accurate time estimation in zebrafish (Danio rerio).
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Rare and de novo coding variants in chromodomain genes in Chiari I malformation.
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Ras controls melanocyte expansion during zebrafish fin stripe regeneration.
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Rearing conditions differentially affect the locomotor behavior of larval zebrafish, but not their response to valproate-induced developmental neurotoxicity.
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Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection.
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Redirecting cardiac growth mechanisms for therapeutic regeneration.
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Regeneration Genetics.
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Regeneration of amputated zebrafish fin rays from de novo osteoblasts.
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Regulated addition of new myocardial and epicardial cells fosters homeostatic cardiac growth and maintenance in adult zebrafish.
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Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b.
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Regulation of zebrafish fin regeneration by vitamin D signaling.
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Regulation of zebrafish heart regeneration by miR-133.
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Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heart.
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Repeated therapeutic lumbar punctures in cryptococcal meningitis - necessity and/or opportunity?
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Reply to Corbeil et al.: Deletion of the transmembrane protein Prom1b in zebrafish disrupts outer-segment morphogenesis and causes photoreceptor degeneration.
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Requirements for the kit receptor tyrosine kinase during regeneration of zebrafish fin melanocytes.
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Resolving Heart Regeneration by Replacement Histone Profiling.
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Restriction of hepatic competence by Fgf signaling.
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Retinal ganglion cell genesis requires lakritz, a Zebrafish atonal Homolog.
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Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration.
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Retinoic acid-mediated gene expression in transgenic reporter zebrafish.
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Retinoid regulation of the zebrafish cyp26a1 promoter.
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Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography.
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Roles for Fgf signaling during zebrafish fin regeneration.
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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.
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SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder.
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SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease.
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Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity.
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Self-organization of apical membrane protein sorting in epithelial cells.
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Sequence and expression of zebrafish foxc1a and foxc1b, encoding conserved forkhead/winged helix transcription factors.
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Sexually dimorphic fin regeneration in zebrafish controlled by androgen/GSK3 signaling.
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Sheath Cell Invasion and Trans-differentiation Repair Mechanical Damage Caused by Loss of Caveolae in the Zebrafish Notochord.
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Silver exposure in developing zebrafish (Danio rerio): persistent effects on larval behavior and survival.
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Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes.
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Silver nanoparticles alter zebrafish development and larval behavior: distinct roles for particle size, coating and composition.
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Silver nanoparticles compromise neurodevelopment in PC12 cells: critical contributions of silver ion, particle size, coating, and composition.
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Single continuous lumen formation in the zebrafish gut is mediated by smoothened-dependent tissue remodeling.
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Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration.
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Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart.
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Single-cell imaging of T cell immunotherapy responses in vivo.
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Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish.
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Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative insults.
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Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis.
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Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase.
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Specification of epibranchial placodes in zebrafish.
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Spinal projection neurons control turning behaviors in zebrafish.
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Spine Patterning Is Guided by Segmentation of the Notochord Sheath.
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Spotlight on zebrafish: the next wave of translational research.
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Stac3 is a component of the excitation-contraction coupling machinery and mutated in Native American myopathy.
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Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina.
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Starvation causes changes in the intestinal transcriptome and microbiome that are reversed upon refeeding.
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Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis.
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Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis.
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Study of host-microbe interactions in zebrafish.
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Subchronic effects of plant alkaloids on anxiety-like behavior in zebrafish.
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Sulfidation of silver nanoparticles: natural antidote to their toxicity.
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Synergistic induction of AHR regulated genes in developmental toxicity from co-exposure to two model PAHs in zebrafish.
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Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration.
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Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes.
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TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone.
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Tafenoquine: A Step toward Malaria Elimination.
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Tales of regeneration in zebrafish.
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Temperature-activated ion channels in neural crest cells confer maternal fever-associated birth defects.
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Temporal and molecular separation of the kit receptor tyrosine kinase's roles in zebrafish melanocyte migration and survival.
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Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue.
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Teratogenic, bioenergetic, and behavioral effects of exposure to total particulate matter on early development of zebrafish (Danio rerio) are not mimicked by nicotine.
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The Affinity of Brominated Phenolic Compounds for Human and Zebrafish Thyroid Receptor β: Influence of Chemical Structure.
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The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes.
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The Human FSGS-Causing ANLN R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes.
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The Macrophage-Specific Promoter mfap4 Allows Live, Long-Term Analysis of Macrophage Behavior during Mycobacterial Infection in Zebrafish.
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The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development.
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The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma.
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The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation.
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The actin nucleator Cordon-bleu is required for development of motile cilia in zebrafish.
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The case for thyroid disruption in early life stage exposures to thiram in zebrafish (Danio rerio).
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The composition of the zebrafish intestinal microbial community varies across development.
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The dynamics of successive induction in larval zebrafish.
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The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis.
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The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure.
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The insecticide synergist piperonyl butoxide inhibits hedgehog signaling: assessing chemical risks.
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The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans.
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The negative side of retinoic acid receptors.
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The organophosphate insecticide diazinon and aging: Neurobehavioral and mitochondrial effects in zebrafish exposed as embryos or during aging.
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The people behind the papers - Yingxi Cao, Ken Poss and Jingli Cao.
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The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion.
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The role of CYP1A inhibition in the embryotoxic interactions between hypoxia and polycyclic aromatic hydrocarbons (PAHs) and PAH mixtures in zebrafish (Danio rerio).
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The role of alpha7 and alpha4beta2 nicotinic receptors in the nicotine-induced anxiolytic effect in zebrafish.
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The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafish.
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The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
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The use of tocofersolan as a rescue agent in larval zebrafish exposed to benzo[a]pyrene in early development.
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The use of zebrafish (Danio rerio) as a model system in neurobehavioral toxicology.
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The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish.
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The zebrafish as a model for complex tissue regeneration.
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The zebrafish embryo model in toxicology and teratology, September 2–3, 2010, Karlsruhe, Germany.
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Thrombocyte Inhibition Restores Protective Immunity to Mycobacterial Infection in Zebrafish.
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Timing of nicotine effects on learning in zebrafish.
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Tissue Repair: A Tendon-see to Regenerate.
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Tissue self-organization underlies morphogenesis of the notochord.
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Total particulate matter from cigarette smoke disrupts vascular development in zebrafish brain (Danio rerio).
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Toward safer multi-walled carbon nanotube design: Establishing a statistical model that relates surface charge and embryonic zebrafish mortality.
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Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration.
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Transcriptional components of anteroposterior positional information during zebrafish fin regeneration.
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Transcriptional programmes underlying cellular identity and microbial responsiveness in the intestinal epithelium.
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Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights.
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Transgene expression in zebrafish: A comparison of retroviral-vector and DNA-injection approaches.
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Transient laminin beta 1a Induction Defines the Wound Epidermis during Zebrafish Fin Regeneration.
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Transient requirement for ganglion cells during assembly of retinal synaptic layers.
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Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration.
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Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants.
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Triphenyl phosphate-induced developmental toxicity in zebrafish: potential role of the retinoic acid receptor.
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Triphenyl phosphate-induced pericardial edema in zebrafish embryos is dependent on the ionic strength of exposure media.
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Tris(1,3-dichloro-2-propyl)phosphate Induces Genome-Wide Hypomethylation within Early Zebrafish Embryos.
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Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium.
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Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour.
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Untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy.
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Uptake, tissue distribution, and toxicity of polystyrene nanoparticles in developing zebrafish (Danio rerio).
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Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity.
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Use of non-mammalian alternative models for neurotoxicological study.
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Using whole mount in situ hybridization to examine thyroid hormone deiodinase expression in embryonic and larval zebrafish: a tool for examining OH-BDE toxicity to early life stages.
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Using zebrafish to understand reciprocal interactions between the nervous and immune systems and the microbial world.
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Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling.
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Vegfaa instructs cardiac muscle hyperplasia in adult zebrafish.
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Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish.
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Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
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Vitamin D Stimulates Cardiomyocyte Proliferation and Controls Organ Size and Regeneration in Zebrafish.
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Voltage-gated sodium channel scn8a is required for innervation and regeneration of amputated adult zebrafish fins.
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Whole-brain activity mapping onto a zebrafish brain atlas.
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Whole-brain interactions underlying zebrafish behavior.
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Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.
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Windows into development: historic, current, and future perspectives on transgenic zebrafish.
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Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates.
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Zebrafish CYP1A expression in transgenic Caenorhabditis elegans protects from exposures to benzo[a]pyrene and a complex polycyclic aromatic hydrocarbon mixture.
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Zebrafish Erc1b mediates motor innervation and organization of craniofacial muscles in control of jaw movement.
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Zebrafish Locomotor Responses Reveal Irritant Effects of Fine Particulate Matter Extracts and a Role for TRPA1.
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Zebrafish Posterior Lateral Line primordium migration requires interactions between a superficial sheath of motile cells and the skin.
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Zebrafish Transcription Factor ORFeome for Gene Discovery and Regulatory Network Elucidation.
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Zebrafish as a model for apolipoprotein biology: comprehensive expression analysis and a role for ApoA-IV in regulating food intake.
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Zebrafish as a neurotoxicological model.
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Zebrafish assessment of cognitive improvement and anxiolysis: filling the gap between in vitro and rodent models for drug development.
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Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists.
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Zebrafish developmental screening of the ToxCast™ Phase I chemical library.
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Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like.
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Zebrafish irritant responses to wildland fire-related biomass smoke are influenced by fuel type, combustion phase, and byproduct chemistry.
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Zebrafish kit mutation reveals primary and secondary regulation of melanocyte development during fin stripe regeneration.
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Zebrafish model systems for developmental neurobehavioral toxicology.
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Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits.
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Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function.
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Zebrafish show long-term behavioral impairments resulting from developmental vitamin D deficiency.
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Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development.
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Zebrafish: a see-through host and a fluorescent toolbox to probe host-pathogen interaction.
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Zebrafish: as an integrative model for twenty-first century toxicity testing.
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hapln1 Defines an Epicardial Cell Subpopulation Required for Cardiomyocyte Expansion During Heart Morphogenesis and Regeneration.
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mTOR-regulated mitochondrial metabolism limits mycobacterium-induced cytotoxicity.
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tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration.
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t⁴ workshop report. Nanotoxicology: "the end of the beginning" - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterials.
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zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish.
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Keywords of People
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Dunn, Timothy,
Assistant Professor of Biomedical Engineering,
Center for Cognitive Neuroscience
-
Erickson, Harold Paul,
James B. Duke Distinguished Professor Emeritus,
Cell Biology
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Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
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Staddon, John E. R.,
James B. Duke Distinguished Professor Emeritus of Psychology and Neuroscience,
Psychology & Neuroscience
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Tobin, David M.,
Associate Professor of Molecular Genetics and Microbiology,
Cell Biology