1-Methyl-3-isobutylxanthine
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Subject Areas on Research
- A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF.
- Activation of calcium channels by cAMP in STC-1 cells is dependent upon Ca2+ calmodulin-dependent protein kinase II.
- Adenosine 3',5'-monophosphate: a modulator of embryonic chick cartilage growth.
- Antimitotic and cytotoxic effects of theophylline in MDA-MB-231 human breast cancer cells.
- Arachidonic acid metabolism in cultured aortic endothelial cells. Effect of cAMP and 3-isobutyl-1-methylxanthine.
- Changes in the rate of laminin and entactin synthesis in F9 embryonal carcinoma cells treated with retinoic acid and cyclic amp.
- Chemoattractant-elicited alterations of cAMP levels in human polymorphonuclear leukocytes require a Ca2+-dependent mechanism which is independent of transmembrane activation of adenylate cyclase.
- Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate.
- Elevated beta-cell calmodulin produces a unique insulin secretory defect in transgenic mice.
- Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts.
- Follicle-stimulating hormone activation of glycogen phosphorylase in the Sertoli cell-enriched rat testis.
- G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization.
- Generation of reactive oxygen species by xanthine derivatives in MDA-MB-231 human breast cancer cells.
- Glucose stimulates and potentiates islet amyloid polypeptide secretion by the B-cell.
- Hormonal activation of ornithine decarboxylase in embryonic chick pelvic cartilage.
- In vitro stimulation of alkaline phosphatase activity in immature embryonic chick pelvic cartilage by adenosine 3'5'-monophosphate.
- Interaction between the second messengers cAMP and Ca2+ in mouse presynaptic taste cells.
- Isobutylmethylxanthine stimulates adenylate cyclase by blocking the inhibitory regulatory protein, Gi.
- Morphological and functional characterization of beta TC-6 cells--an insulin-secreting cell line derived from transgenic mice.
- Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis.
- Pentoxifylline and other methyl xanthines inhibit interleukin-2 receptor expression in human lymphocytes.
- Phosphorylation of the beta-adrenergic receptor in intact cells: relationship to heterologous and homologous mechanisms of adenylate cyclase desensitization.
- Protein kinase A, cytosolic calcium, and phosphate uptake in human proximal renal cells.
- Protein phosphatases mediate depotentiation induced by high-intensity theta-burst stimulation.
- Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP.
- Regulation of cholecystokinin secretion by calcium-dependent calmodulin kinase II: differential effects of phenylalanine and cAMP.
- Regulation of insulin secretion from novel engineered insulinoma cell lines.
- Regulation of phosphorylation of aminoacyl-tRNA synthetases in the high molecular weight core complex in reticulocytes.
- Roles of the AMP-activated and cyclic-AMP-dependent protein kinases in the adrenaline-induced inactivation of acetyl-CoA carboxylase in rat adipocytes.
- Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level.
- cAMP and forskolin decrease gamma-aminobutyric acid-gated chloride flux in rat brain synaptoneurosomes.
- cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure.