Carcinogenicity Tests

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  Subject Areas on Research

  • A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity. 
  • Analysis of renal cell transformation following exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-L-cysteine in vitro. 
  • Atypical tubule hyperplasia and renal tubule tumors in conventional rats on 90-day toxicity studies. 
  • Bayesian models for multivariate current status data with informative censoring. 
  • Carcinogenicity of inhaled benzene in CBA mice. 
  • Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion. 
  • Evolution of a tumorigenic property conferred by glycophosphatidyl-inositol membrane anchors of carcinoembryonic antigen gene family members during the primate radiation. 
  • Genetic instability and tumorigenesis: introduction. 
  • Herpes simplex virus (HSV)-mediated ICAM-1 gene transfer abrogates tumorigenicity and induces anti-tumor immunity. 
  • Isolation and characterization of a novel human prostatic stromal cell culture: DuK50. 
  • Local production of TGF beta1 inhibits cerebral edema, enhances TNF-alpha induced apoptosis and improves survival in a murine glioma model. 
  • Magnetic resonance microscopy of chemically-induced liver foci. 
  • Mesotheliomas induced in rats by the fibrous mineral erionite are independent from p53 alterations. 
  • Modeling tumor onset and multiplicity using transition models with latent variables. 
  • Morphological and neoplastic transformation of C3H/10T1/2 Cl 8 mouse embryo cells by insoluble carcinogenic nickel compounds. 
  • Mutation, DNA strand cleavage and nitric oxide formation caused by N-nitrosoproline with sunlight: a possible mechanism of UVA carcinogenicity. 
  • New murine cell line derived from a spontaneous lung tumor induces paraneoplastic syndromes. 
  • Resolving mechanisms of toxicity while pursuing ecotoxicological relevance? 
  • Retinoic acid receptor-beta2 promoter methylation in random periareolar fine needle aspiration. 
  • Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. 
  • Statistical analysis of skin tumor data from Tg.AC mouse bioassays. 
  • The Ras-related protein AGS1/RASD1 suppresses cell growth. 
  • Ultrastructural alterations in liver of medaka (Oryzias latipes) exposed to diethylnitrosamine. 
  • Use of genetically modified mouse models for evaluation of carcinogenic risk: considerations for the laboratory animal scientist. 
  • Weight of the evidence on the human carcinogenicity of 2,4-D. 
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  Keywords of People

  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Immunology