Inflammatory Bowel Diseases

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  Subject Areas on Research

  • A Programme for Risk Assessment and Minimisation of Progressive Multifocal Leukoencephalopathy Developed for Vedolizumab Clinical Trials. 
  • A case of vanishing bile duct syndrome and IBD secondary to Hodgkin's lymphoma. 
  • A functional genomics predictive network model identifies regulators of inflammatory bowel disease. 
  • Aberrant expression of maspin in idiopathic inflammatory bowel disease is associated with disease activity and neoplastic transformation. 
  • Accuracy of the medication list in the electronic health record-implications for care, research, and improvement. 
  • An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease. 
  • An i2b2-based, generalizable, open source, self-scaling chronic disease registry. 
  • Anti-TNF and thiopurine therapy in pregnant IBD patients does not significantly alter a panel of B-cell and T-cell subsets in 1-year-old infants. 
  • Anxiety and Depressive Symptoms Are Not Associated With Future Pediatric Crohn's Disease Activity. 
  • Assessing patient preferences for treatment options and process of care in inflammatory bowel disease: a critical review of quantitative data. 
  • Association of Transition Readiness to Intentional Self-Regulation and Hopeful Future Expectations in Youth With Illness. 
  • Bacterial-mucosal interactions in inflammatory bowel disease: an alliance gone bad. 
  • Bromelain treatment decreases secretion of pro-inflammatory cytokines and chemokines by colon biopsies in vitro. 
  • CD4+CD45RBHi T cell transfer induced colitis in mice is accompanied by osteopenia which is treatable with recombinant human osteoprotegerin. 
  • CT Versus MR Enterography: Point-CT Enterography Remains Essential to Imaging Patients With Inflammatory Bowel Disease in the Acute Setting. 
  • Cavitary lung nodules as an extraintestinal manifestation of ulcerative colitis. 
  • Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT. 
  • Chronic recurrent multifocal osteomyelitis associated with chronic inflammatory bowel disease in children. 
  • Clinical and histologic findings in patients with uveal melanomas after taking tumor necrosis factor-α inhibitors. 
  • Clostridium Difficile Infection from a Surgical Perspective. 
  • Clostridium difficile infection and treatment in the pediatric inflammatory bowel disease population. 
  • Colorectal cancer surveillance in inflammatory bowel disease: Practice guidelines and recent developments. 
  • Comparison of Assays for Therapeutic Monitoring of Infliximab and Adalimumab in Patients With Inflammatory Bowel Diseases. 
  • Cost-effectiveness of Venous Thromboembolism Prophylaxis After Hospitalization in Patients With Inflammatory Bowel Disease. 
  • Cytomegalovirus infection increases the risk for inflammatory bowel disease. 
  • Defying Occam's Razor: Colonic Luminal Endometriosis in an Adolescent With Crohn's Disease. 
  • Diet rapidly and reproducibly alters the human gut microbiome. 
  • Dietary Salt Exacerbates Experimental Colitis. 
  • Disrupted metabolic signatures in amniotic fluid associated with increased risk of intestinal inflammation in cesarean section offspring. 
  • Double Negativity for Expression of YAP1 and CDX2 Defines an Aggressive Type of Colitis-associated Cancer. 
  • Editorial: awareness and prevention of intravenous iron-induced hypophosphataemia. 
  • Editorial: rising rates of venous thromboembolism among hospitalised patients with inflammatory bowel disease in the USA-authors' reply. 
  • Effect of Diagnosis on Outcomes in the Setting of Enhanced Recovery Protocols. 
  • Effect of a Practice-wide Anti-TNF Proactive Therapeutic Drug Monitoring Program on Outcomes in Pediatric Patients with Inflammatory Bowel Disease. 
  • Endothelial dysfunction in chronic inflammatory diseases. 
  • Epigenetic control of intestinal barrier function and inflammation in zebrafish. 
  • Evaluation of SLC11A1 as an inflammatory bowel disease candidate gene. 
  • Exploring the generalist-subspecialist interface in internal medicine. 
  • Factors associated with reduced infliximab exposure in the treatment of pediatric autoimmune disorders: a cross-sectional prospective convenience sampling study. 
  • Gender-specific differences in pelvic organ function after proctectomy for inflammatory bowel disease. 
  • Giardia hinders growth by disrupting nutrient metabolism independent of inflammatory enteropathy. 
  • Glutamine therapy improves outcome of in vitro and in vivo experimental colitis models. 
  • HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease. 
  • Helicobacter typhlonius and Helicobacter rodentium differentially affect the severity of colon inflammation and inflammation-associated neoplasia in IL10-deficient mice. 
  • Human-Centered Design of a Clinical Decision Support for Anemia Screening in Children with Inflammatory Bowel Disease. 
  • Immunology of inflammatory bowel disease: summary of the proceedings of the Subcommittee on Immunosuppressive Use in IBD. 
  • Immunosuppressive therapy in pediatric inflammatory bowel disease: results of a survey of the North American Society for Pediatric Gastroenterology and Nutrition. Subcommittee on Immunosuppressive Use of the Pediatric IBD Collaborative Research Forum. 
  • Immunosuppressive/Autoimmune Disorders. 
  • Improving Quality in the Care of Patients with Inflammatory Bowel Diseases. 
  • Increased risk for non-melanoma skin cancer in patients with inflammatory bowel disease. 
  • Increasing rates of venous thromboembolism among hospitalised patients with inflammatory bowel disease: a nationwide analysis. 
  • Inflammatory Bowel Disease Patients' Willingness to Accept Medication Risk to Avoid Future Disease Relapse. 
  • Inflammatory Bowel Disease in Children With Systemic Juvenile Idiopathic Arthritis. 
  • Inflammatory bowel disease after liver transplantation: risk factors for recurrence and de novo disease. 
  • Inflammatory bowel disease following solid organ transplantation. 
  • Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs. 
  • Infliximab and Adalimumab Concentrations May Vary Between the Enzyme-Linked Immunosorbent Assay and the Homogeneous Mobility Shift Assay in Patients With Inflammatory Bowel Disease: A Prospective Cross-Sectional Observational Study. 
  • Intestinal Inflammation Promotes MDL-1+ Osteoclast Precursor Expansion to Trigger Osteoclastogenesis and Bone Loss. 
  • Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium. 
  • Letter to the Editor Regarding Optimizing Selection of Biologics in Inflammatory Bowel Disease: Development of an Online Patient Decision Aid Using Conjoint Analysis. 
  • Letter: fighting the battle but losing the war-inflammatory bowel disease and venous thromboembolism. Authors' reply. 
  • Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel Targets. 
  • MR Imaging Evaluation of Inflammatory Bowel Disease in Children:: Where Are We Now in 2019. 
  • Mercaptopurine metabolite results in clinical gastroenterology practice. 
  • Meta-analyses of colorectal cancer risk factors. 
  • Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha. 
  • NFIL3-deficient mice develop microbiota-dependent, IL-12/23-driven spontaneous colitis. 
  • Neonatal co-infection with helicobacter species markedly accelerates the development of inflammation-associated colonic neoplasia in IL-10(-/-) mice. 
  • Neurologic manifestations of gastrointestinal disease. 
  • Nonmelanoma skin cancer in inflammatory bowel disease: a review. 
  • Patients With Inflammatory Bowel Diseases Are at Higher Risk for Meningitis. 
  • Platelet hyaluronidase-2: an enzyme that translocates to the surface upon activation to function in extracellular matrix degradation. 
  • Postoperative Venous Thromboembolism in Patients Undergoing Abdominal Surgery for IBD: A Common but Rarely Addressed Problem. 
  • Preoperative biological therapy and short-term outcomes of abdominal surgery in patients with inflammatory bowel disease. 
  • Prevalence and significance of inflammatory bowel disease-like morphologic features in collagenous and lymphocytic colitis. 
  • Prevalence of factor V G1691A (Leiden), prothrombin G20210A, and methylene tetrahydrofolate reductase C677T thrombophilic mutations in children with inflammatory bowel disease. 
  • Relationships between sclerosing cholangitis, inflammatory bowel disease, and cancer in patients undergoing liver transplantation. 
  • Reproduction and Growth in a Murine Model of Early Life-Onset Inflammatory Bowel Disease. 
  • Risk of Postpartum Flare Hospitalizations in Patients with Inflammatory Bowel Disease Persists After Six Months. 
  • Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease. 
  • Role of mast cells in inflammatory bowel disease and inflammation-associated colorectal neoplasia in IL-10-deficient mice. 
  • Selective role for TRPV4 ion channels in visceral sensory pathways. 
  • Spatial organization of bacterial flora in normal and inflamed intestine: a fluorescence in situ hybridization study in mice. 
  • Spectrum of diseases associated with pyoderma gangrenosum and correlation with effectiveness of therapy: New insights on the diagnosis and therapy of comorbid hidradenitis suppurativa. 
  • Structured reporting of CT enterography for inflammatory bowel disease: effect on key feature reporting, accuracy across training levels, and subjective assessment of disease by referring physicians. 
  • Substance P binding sites on intestinal lymphoid aggregates and blood vessels in inflammatory bowel disease correspond to authentic NK-1 receptors. 
  • Survey of gastroenterologists' awareness and implementation of AGA guidelines on osteoporosis in inflammatory bowel disease patients: are the guidelines being used and what are the barriers to their use? 
  • Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation. 
  • Tetomilast: new promise for phosphodiesterase-4 inhibitors? 
  • The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. 
  • The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis. 
  • The association between genetically elevated polyunsaturated fatty acids and risk of cancer. 
  • The scaffold-dependent function of RIPK1 in dendritic cells promotes injury-induced colitis. 
  • Treatment with oral bromelain decreases colonic inflammation in the IL-10-deficient murine model of inflammatory bowel disease. 
  • Untreated Hypertension and Subsequent Incidence of Colorectal Cancer: Analysis of a Nationwide Epidemiological Database. 
  • Update on multi-center clinical trials in the United States. 
  • Updates in colorectal cancer screening in inflammatory bowel disease. 
  • Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner. 
  • What Clues Can We Use From Primary Sclerosing Cholangitis With Inflammatory Bowel Disease Phenotypes? 
  • Which Patients Require Extended Thromboprophylaxis After Colectomy? Modeling Risk and Assessing Indications for Post-discharge Pharmacoprophylaxis. 
  • Women's Willingness to Accept Risks of Medication for Inflammatory Bowel Disease During Pregnancy. 
  • rHuKGF ameliorates symptoms in DSS and CD4(+)CD45RB(Hi) T cell transfer mouse models of inflammatory bowel disease. 
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  Keywords of People

  • Grego, Sonia, Associate Research Professor in the Department of Electrical and Computer Engineering, Electrical and Computer Engineering
  • Lee, Kate, House Staff, Medicine
  • Rassadkina, Yelizaveta, Student, Molecular Genetics and Microbiology
  • Zhang, Cecelia, Assistant Professor of Medicine, Medicine, Gastroenterology