Lipid Peroxidation

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  Subject Areas on Research

  • A review of molecular mechanisms linked to potential renal injury agents in tropical rural farming communities. 
  • Abnormal exhaled ethane concentrations in scleroderma. 
  • Absence of direct antioxidant effects from volatile anesthetics in primary mixed neuronal-glial cultures. 
  • Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis. 
  • Antioxidant and cytotoxic tocopheryl quinones in normal and cancer cells. 
  • Antioxidant lazaroid U-74006F improves renal function and reduces the expression of cytokines, inducible nitric oxide synthase, and MHC antigens in a syngeneic renal transplant model. Partial support for the response-to-injury hypothesis. 
  • Antioxidant responses and oxidative stress in sheepshead minnow larvae exposed to Corexit 9500^® or its component surfactant, DOSS. 
  • Assessment of the phototoxicity of weathered Alaska North Slope crude oil to juvenile pink salmon. 
  • Catabolism of (2E)-4-hydroxy-2-nonenal via ω- and ω-1-oxidation stimulated by ketogenic diet. 
  • Cataract formation in a strain of rats selected for high oxidative stress. 
  • Citrate and vitamin E blunt the shock wave-induced free radical surge in an in vitro cell culture model. 
  • Comparative proteomic analysis of proteins in response to simulated acid rain in Arabidopsis. 
  • Comparison of lung protective ventilation strategies in a rabbit model of acute lung injury. 
  • Competitive apnea and its effect on the human brain: focus on the redox regulation of blood-brain barrier permeability and neuronal-parenchymal integrity. 
  • Concentrations of urinary 8-hydroxy-2'-deoxyguanosine and 8-isoprostane in women exposed to woodsmoke in a cookstove intervention study in San Marcos, Peru. 
  • Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination. 
  • Crosslinking of apolipoprotein E by products of lipid peroxidation. 
  • Current status of antioxidant therapy for Alzheimer's Disease. 
  • Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. 
  • Cyclosporine increases local glomerular synthesis of reactive oxygen species in rats: effect of vitamin E on cyclosporine nephrotoxicity. 
  • DNA adducts in human pancreatic tissues and their potential role in carcinogenesis. 
  • Depletion of total antioxidant capacity in type 2 diabetes. 
  • Dietary regulation of catabolic disposal of 4-hydroxynonenal analogs in rat liver. 
  • Differences in the metabolic response to exogenous homocysteine in juvenile and adult rabbits. 
  • Differential regulation of c-jun and CREB by acrolein and 4-hydroxynonenal. 
  • Differential susceptibility of fish and rat liver cells to oxidative stress and cytotoxicity upon exposure to prooxidants 
  • E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures. 
  • ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis. 
  • Effect of potent redox-modulating manganese porphyrin, MnTM-2-PyP, on the Na(+)/H(+) exchangers NHE-1 and NHE-3 in the diabetic rat. 
  • Effects of a single bout of ultraendurance exercise on lipid levels and susceptibility of lipids to peroxidation in triathletes. 
  • Effects of beta-carotene repletion on beta-carotene absorption, lipid peroxidation, and neutrophil superoxide formation in young men. 
  • Effects of phytanic acid on the vitamin E status, lipid composition and physical properties of retinal cell membranes: implications for adult Refsum disease. 
  • Endothelial superoxide production is altered in sheep programmed by early gestation dexamethasone exposure. 
  • Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair. 
  • Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins. 
  • Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism. 
  • Gender differences in exercise-induced changes in sex hormone levels and lipid peroxidation in athletes participating in the Hawaii Ironman triathlon. Ginsburg-gender and exercise-induced lipid peroxidation. 
  • Glutathionylated 4-hydroxy-2-(E)-alkenal enantiomers in rat organs and their contributions toward the disposal of 4-hydroxy-2-(E)-nonenal in rat liver. 
  • Human halothane metabolism, lipid peroxidation, and cytochromes P(450)2A6 and P(450)3A4. 
  • Hypothesis: is lung disease after silicate inhalation caused by oxidant generation? 
  • Identification of a negative feedback loop in biological oxidant formation fegulated by 4-hydroxy-2-(E)-nonenal. 
  • In Vivo Assessment of Ferroptosis and Ferroptotic Stress in Mice. 
  • In vivo assessment of free radical activity during shock wave lithotripsy using a microdialysis system: the renoprotective action of allopurinol. 
  • Increase in oxidative stress as measured by cerebrospinal fluid lipid peroxidation during treatment for childhood acute lymphoblastic leukemia. 
  • Increased palmitate intake: higher acylcarnitine concentrations without impaired progression of β-oxidation. 
  • Induction of oxidative cell damage by photo-treatment with zinc meta N-methylpyridylporphyrin. 
  • Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. 
  • Interleukin 1-induced production of nitric oxide inhibits benzenetriol-mediated oxidative injury in rat hepatocytes. 
  • Intramuscular triacylglycerol and insulin resistance: guilty as charged or wrongly accused? 
  • Leptin directly alters lipid partitioning in skeletal muscle. 
  • Lipid hydroperoxy and hydroxy derivatives in copper-catalyzed oxidation of low density lipoprotein. 
  • Long-term cellular effects in humans chronically exposed to ionizing radiation. 
  • M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice. 
  • Manganese-porphyrin reactions with lipids and lipoproteins. 
  • Mechanisms of the antioxidant effects of nitric oxide. 
  • Metalloporphyrins are potent inhibitors of lipid peroxidation. 
  • Metallothionein alleviates glutathione depletion-induced oxidative cardiomyopathy in murine hearts. 
  • Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading. 
  • Nano-C60 cytotoxicity is due to lipid peroxidation. 
  • Nucleotide metabolism is linked to cysteine availability. 
  • Nutrition Modulation of Cardiotoxicity and Anticancer Efficacy Related to Doxorubicin Chemotherapy by Glutamine and ω-3 Polyunsaturated Fatty Acids. 
  • Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production. 
  • Oxidants, antioxidants and the ischemic brain. 
  • Oxidative changes in cerebral spinal fluid phosphatidylcholine during treatment for acute lymphoblastic leukemia. 
  • Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa. 
  • Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos. 
  • Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential. 
  • Oxidative stress from diverse developmental neurotoxicants: antioxidants protect against lipid peroxidation without preventing cell loss. 
  • Oxidative stress in human abdominal aortic aneurysms: a potential mediator of aneurysmal remodeling. 
  • Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories. 
  • Oxidative stress, antioxidant defenses and nitric oxide production following hyperoxic exposures. 
  • Oxidized lipid-mediated alterations in proteoglycan metabolism in cultured pulmonary endothelial cells. 
  • Partial liquid ventilation with perflubron attenuates in vivo oxidative damage to proteins and lipids. 
  • Perfluorooctyl bromide (perflubron) attenuates oxidative injury to biological and nonbiological systems. 
  • Perinatal environmental tobacco smoke exposure in rhesus monkeys: critical periods and regional selectivity for effects on brain cell development and lipid peroxidation. 
  • Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells. 
  • Phospholipid-protein adducts of lipid peroxidation: synthesis and study of new biotinylated phosphatidylcholines. 
  • Phototoxicity in human retinal pigment epithelial cells promoted by hypericin, a component of St. John's wort. 
  • Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells. 
  • Protective effect of 21-aminosteroid pretreatment in peripheral nerve low-load crush injury in mature and immature rats. 
  • Rational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents. 
  • Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment. 
  • Shock wave lithotripsy causes ipsilateral renal injury remote from the focal point: the role of regional vasoconstriction. 
  • Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. 
  • Synthesis and in vitro antioxidant properties of manganese(III) beta-octabromo-meso-tetrakis(4-carboxyphenyl)porphyrin. 
  • The Arabidopsis sn-1-specific mitochondrial acylhydrolase AtDLAH is positively correlated with seed viability. 
  • The Hippo Pathway Effector YAP Promotes Ferroptosis via the E3 Ligase SKP2. 
  • The nitric oxide donor S-nitroso-N-acetylpenicillamine (SNAP) increases free radical generation and degrades left ventricular function after myocardial ischemia-reperfusion. 
  • The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages. 
  • The relationship between plasma lipid peroxidation products and primary graft dysfunction after lung transplantation is modified by donor smoking and reperfusion hyperoxia. 
  • TiO₂ Nanoparticle-Induced Oxidation of the Plasma Membrane: Importance of the Protein Corona. 
  • Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants. 
  • Urinary F2-isoprostanes and the risk of hypertension. 
  • Urinary F2-isoprostanes are not associated with increased risk of type 2 diabetes. 
  • Urinary Isoprostane Levels and Age-Related Macular Degeneration. 
  • Urinary biomarkers of oxidative status. 
  • [Oxidative and anti-oxidative effects of ambroxol on acute hydrochloric acid-induced lung injury in rats]. 
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  Keywords of People

  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology