Glucose Clamp Technique
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Subject Areas on Research
- A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.
- Acute effects of hyperinsulinemia and hyperglycemia on vascular inflammatory biomarkers and endothelial function in overweight and obese humans.
- Age attenuates leucine oxidation after eccentric exercise.
- Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene.
- BMI, RQ, diabetes, and sex affect the relationships between amino acids and clamp measures of insulin action in humans.
- Bypassing the duodenum does not improve insulin resistance associated with diet-induced obesity in rodents.
- Ceramide content is increased in skeletal muscle from obese insulin-resistant humans.
- Comparative effects of acute hypoglycemia and hyperglycemia on pro-atherothrombotic biomarkers and endothelial function in non-diabetic humans.
- Comparison of insulin sensitivity assessment indices with euglycemic-hyperinsulinemic clamp data after a dietary and exercise intervention in older adults.
- Contributions of fat and protein to the incretin effect of a mixed meal.
- Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.
- Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding.
- Effect of Progressive Weight Loss on Lactate Metabolism: A Randomized Controlled Trial.
- Effects of short-term very low-calorie diet on intramyocellular lipid and insulin sensitivity in nondiabetic and type 2 diabetic subjects.
- Exercise increases muscle GLUT-4 levels and insulin action in subjects with impaired glucose tolerance.
- Human aging is associated with altered TNF-alpha production during hyperglycemia and hyperinsulinemia.
- Human brain glycogen metabolism during and after hypoglycemia.
- Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans.
- Impact of olanzapine or risperidone treatment on insulin sensitivity in schizophrenia or schizoaffective disorder.
- Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose.
- Impaired insulin response after oral but not intravenous glucose in heart- and liver-transplant recipients.
- Improved glycemic control enhances the incretin effect in patients with type 2 diabetes.
- Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.
- Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt-mTOR-S6K1 pathway and insulin sensitivity.
- Long-term effects of a high-carbohydrate diet and exercise on insulin action in older subjects with impaired glucose tolerance.
- Plasma acylcarnitines during insulin stimulation in humans are reflective of age-related metabolic dysfunction.
- Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis.
- Regulation of islet hormone release and gastric emptying by endogenous glucagon-like peptide 1 after glucose ingestion.
- Suppression of glucose production by GLP-1 independent of islet hormones: a novel extrapancreatic effect.
- β-Cell Sensitivity to GLP-1 in Healthy Humans Is Variable and Proportional to Insulin Sensitivity.