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Subject Areas on Research
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A T cell-specific transcriptional enhancer within the human T cell receptor delta locus.
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A Therapeutic Antibody for Cancer, Derived from Single Human B Cells.
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A case of infantile acute lymphoblastic leukemia presenting with rearrangement of MLL at 11q23 and apparent insertion or translocation at 10p12.
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A family of human Y chromosomes has dispersed throughout northern Eurasia despite a 1.8-Mb deletion in the azoospermia factor c region.
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A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone.
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A systematic analysis of recombination activity and genotype-phenotype correlation in human recombination-activating gene 1 deficiency.
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A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence.
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Allele separation facilitates interpretation of potential splicing alterations and genomic rearrangements.
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Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance.
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BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma.
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Biclonal evolution of chronic lymphocytic leukaemia.
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Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop 'G4 Kissing' interaction.
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Characterization of the interleukin 1 receptor-associated kinase 4 (IRAK4)-encoding gene in salmonid fish: the functional copy is rearranged in Oncorhynchus mykiss and that factor can impair TLR signaling in mammalian cells.
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Chromosomal abnormalities and molecular genetics of non-Hodgkin's lymphoma.
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Chromosomal microarray analysis in clinical evaluation of neurodevelopmental disorders-reporting a novel deletion of SETDB1 and illustration of counseling challenge.
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Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair.
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Clinical features, tumor biology, and prognosis associated with MYC rearrangement and Myc overexpression in diffuse large B-cell lymphoma patients treated with rituximab-CHOP.
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CloneRetriever: An Automated Algorithm to Identify Clonal B and T Cell Gene Rearrangements by Next-Generation Sequencing for the Diagnosis of Lymphoid Malignancies.
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Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution.
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Composite lymphoma of mycosis fungoides and cutaneous small B-cell lymphoma in a 73-year-old male patient.
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Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes.
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DNA sequence characterization and molecular evolution of MAT1 and MAT2 mating-type loci of the self-compatible ascomycete mold Neosartorya fischeri.
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Deletion-mutant epidermal growth factor receptor in human gliomas: effects of type II mutation on receptor function.
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Deletions and rearrangements inactivate the p16INK4 gene in human glioma cells.
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Developmental activation of the TCR alpha enhancer requires functional collaboration among proteins bound inside and outside the core enhancer.
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Diffuse Large B-Cell Lymphoma Version 1.2016.
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Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.
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Double IGHV DNA gene rearrangements in CLL: influence of mixed-mutated and -unmutated rearrangements on outcomes in CLL.
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Dramatic mitochondrial gene rearrangements in the hermit crab Pagurus longicarpus (Crustacea, anomura).
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Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
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EBV+ high-grade B cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements: a multi-institutional study.
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Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival.
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Evidence for Dobzhansky-Muller incompatibilites contributing to the sterility of hybrids between Mimulus guttatus and M. nasutus.
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Expanding the Spectrum of EBV-positive Marginal Zone Lymphomas: A Lesion Associated With Diverse Immunodeficiency Settings.
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Follicular lymphoma with prominent Dutcher body formation: a pathologic study of 3 cases in comparison with nodal or splenic lymphoplasmacytic lymphoma and marginal zone lymphoma.
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Frequent TMPRSS2-ERG rearrangement in prostatic small cell carcinoma detected by fluorescence in situ hybridization: the superiority of fluorescence in situ hybridization over ERG immunohistochemistry.
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Gene segment selection in V(D)J recombination: accessibility and beyond.
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Generation and characterization of a mouse/human chimeric antibody directed against extracellular matrix protein tenascin.
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Genetic structure and DNA sequences at junctions involved in the rearrangements of Bacillus subtilis strains carrying the trpE26 mutation.
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Genome-wide mapping of spontaneous genetic alterations in diploid yeast cells.
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Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis.
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Hairy Cell Leukemia, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.
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Heart rate decrease during crizotinib treatment and potential correlation to clinical response.
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Hepatosplenic T-cell lymphoma: an unusual case of a gamma delta T-cell lymphoma with a blast-like terminal transformation.
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High dose cyclophosphamide plus recombinant human granulocyte-colony stimulating factor (rhG-CSF) in the treatment of follicular, low grade non-Hodgkin's lymphoma: CALGB 9150.
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High levels of nuclear MYC protein predict the presence of MYC rearrangement in diffuse large B-cell lymphoma.
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High-grade B cell lymphoma, unclassifiable, with blastoid features: an unusual morphological subgroup associated frequently with BCL2 and/or MYC gene rearrangements and a poor prognosis.
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Hobnail variant of papillary thyroid carcinoma: an institutional case series and molecular profile.
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In situ studies of the antigen-driven somatic hypermutation of immunoglobulin genes.
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In situ studies of the germinal center reaction.
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Inclusion of a sensitivity control to add a quality-control parameter and improve reproducibility in BCR, immunoglobulin, and T-cell receptor gene-rearrangement studies.
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Infantile leukemia-What factors determine its distinct biological nature? Clinicopathological study of 78 cases.
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Intracranial Ewing sarcoma.
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MYC/BCL2 double-hit high-grade B-cell lymphoma.
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Mantle Cell Lymphoma With MYC Rearrangement: A Report of 17 Patients.
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Methods for Study of Mouse T Cell Receptor α and β Gene Rearrangements.
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Molecular analysis of highly enriched populations of T-cell-depleted monocytes.
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Molecular evidence of a genotypically novel large T-cell lymphoma after anti-CD4 therapy for refractory mycosis fungoides.
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Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line.
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Nanopore sequencing of complex genomic rearrangements in yeast reveals mechanisms of repeat-mediated double-strand break repair.
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Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells.
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Neural cell adhesion molecule (CD56)-positive acute myelogenous leukemia and myelodysplastic and myeloproliferative syndromes.
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Oncogenes and anti-oncogenes in human central nervous system tumors.
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Orchestrating T-cell receptor α gene assembly through changes in chromatin structure and organization.
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PAX8/PPARγ rearrangement in thyroid nodules predicts follicular-pattern carcinomas, in particular the encapsulated follicular variant of papillary carcinoma.
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Peripheral T-cell lymphoma with unusual clinical presentation of rhabdomyolysis.
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Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
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Prospective analysis of TEL gene rearrangements in childhood acute lymphoblastic leukemia: a Children's Oncology Group study.
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Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling.
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Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell lymphoma patients treated with rituximab-CHOP.
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Recombination between retrotransposons as a source of chromosome rearrangements in the yeast Saccharomyces cerevisiae.
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Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers.
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Sakacin P non-producing Lactobacillus sakei strains contain homologues of the sakacin P gene cluster.
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Sequence signatures of a recent chromosomal rearrangement in Drosophila mojavensis.
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Single nucleotide polymorphisms act as modifiers and correlate with the development of medullary and simultaneous medullary/papillary thyroid carcinomas in 2 large, non-related families with the RET V804M proto-oncogene mutation.
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Structural alterations of the epidermal growth factor receptor gene in human gliomas.
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T-lymphoblastic lymphoma and acute myeloid leukaemia transformed from myeloid neoplasm with eosinophilia: a divergent evolution of myeloid neoplasm with monosomy 7 but no detectable tyrosine kinase gene rearrangements designated by the WHO Classification.
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TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome.
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The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks.
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The structural basis of repertoire shift in an immune response to phosphocholine.
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Transformation of follicular lymphoma to precursor B-cell lymphoblastic lymphoma with c-myc gene rearrangement as a critical event.
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Triple-hit B-cell Lymphoma With MYC, BCL2, and BCL6 Translocations/Rearrangements: Clinicopathologic Features of 11 Cases.
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V(D)J recombinase-mediated processing of coding junctions at cryptic recombination signal sequences in peripheral T cells during human development.
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VCL-ALK renal cell carcinoma in children with sickle-cell trait: the eighth sickle-cell nephropathy?
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Keywords of People