Leukemia, Lymphocytic, Chronic, B-Cell
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Subject Areas on Research
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"Primum non nocere": the addition of granulocyte-macrophage colony stimulating factor to alemtuzumab in chronic lymphocytic leukemia.
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5-year survival in patients with relapsed or refractory chronic lymphocytic leukemia in a randomized, phase III trial of fludarabine plus cyclophosphamide with or without oblimersen.
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98% IGHV gene identity is the optimal cutoff to dichotomize the prognosis of Chinese patients with chronic lymphocytic leukemia.
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A genomic approach to improve prognosis and predict therapeutic response in chronic lymphocytic leukemia.
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A novel diagnostic approach for the classification of small B-cell lymphoid neoplasms based on the NanoString platform.
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A pathobiological role of the insulin receptor in chronic lymphocytic leukemia.
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A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin's lymphoma.
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A phase II study of single agent gemcitabine in relapsed or refractory follicular or small lymphocytic non-Hodgkin lymphomas: a Hoosier Oncology Group Study.
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A pilot study of high-intensity interval training in older adults with treatment naïve chronic lymphocytic leukemia.
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A retrospective comparison of venetoclax alone or in combination with an anti-CD20 monoclonal antibody in R/R CLL.
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A single tube, four-color flow cytometry assay for evaluation of ZAP-70 and CD38 expression in chronic lymphocytic leukemia.
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A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome.
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Adverse event burden in older patients with CLL receiving bendamustine plus rituximab or ibrutinib regimens: Alliance A041202.
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Alemtuzumab in relapsed or refractory chronic lymphocytic leukemia and prolymphocytic leukemia.
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Allogeneic stem cell transplantation for chronic lymphocytic leukemia in the era of novel agents.
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Analysis of age, estimated creatinine clearance and pretreatment hematologic parameters as predictors of fludarabine toxicity in patients treated for chronic lymphocytic leukemia: a CALGB (9011) coordinated intergroup study.
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Apolipoprotein E genotype as a determinant of survival in chronic lymphocytic leukemia.
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Application of a sequential multiple assignment randomized trial (SMART) design in older patients with chronic lymphocytic leukemia.
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Assessment of the Efficacy of Therapies Following Venetoclax Discontinuation in CLL Reveals BTK Inhibition as an Effective Strategy.
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Association of elevated serumfree light chains with chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis.
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Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis.
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Autoimmune disease and chronic lymphocytic leukemia: autoimmune hemolytic anemia, pure red cell aplasia, and autoimmune thrombocytopenia.
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Autologous and allogeneic hematopoietic cell transplantation for diffuse large B-cell lymphoma-type Richter syndrome.
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Axillary lymph nodes: mammographic, pathologic, and clinical correlation.
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B-lymphoblastic leukemia in a patient with chronic lymphocytic leukemia: Sequential development of biclonal B-cell neoplasms over a 23-year period in a single individual.
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Biclonal evolution of chronic lymphocytic leukaemia.
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CD38 variation as a prognostic factor in chronic lymphocytic leukemia.
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CLL cell apoptosis induced by nitric oxide synthase inhibitors: correlation with lipid solubility and NOS1 dissociation constant.
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Carcinogenicity of inhaled benzene in CBA mice.
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Cardiac tamponade in a patient with chronic lymphocytic leukemia.
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Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma With Secondary Acquisition of t(11;14)(q13;q32)/CCND1-IGH: A Rare Variant Of Richter Transformation to Mantle Cell Lymphoma.
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Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology.
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Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function.
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Chronic lymphocytic leukemia cell CD38 expression and inducible nitric oxide synthase expression are associated with serum IL-4 levels.
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Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8+ T cells and impede CAR T-cell efficacy.
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Chronic lymphocytic leukemia in African Americans.
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Chronic lymphocytic leukemia with t(6;14) (p21;q32) CCND3-IGH: CCND3 rearrangement does not necessarily define a cyclin D1-negative mantle cell lymphoma.
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Chronic lymphocytic leukemia/small lymphocytic lymphoma, version 1.2015.
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Clinical and biological relevance of genomic heterogeneity in chronic lymphocytic leukemia.
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Clinical and molecular predictors of disease severity and survival in chronic lymphocytic leukemia.
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Clinical aspects of monoclonal B-cell lymphocytosis.
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Clinical outcomes in chronic lymphocytic leukaemia associated with expression of CD5, a negative regulator of B-cell receptor signalling.
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Commentary: Comparison of current flow cytometry methods for monoclonal B cell lymphocytosis detection.
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Common genetic polymorphisms contribute to the association between chronic lymphocytic leukaemia and non-melanoma skin cancer.
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Common occurrence of monoclonal B-cell lymphocytosis among members of high-risk CLL families.
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Common variants within 6p21.31 locus are associated with chronic lymphocytic leukaemia and, potentially, other non-Hodgkin lymphoma subtypes.
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Comparative analysis of targeted novel therapies in relapsed, refractory chronic lymphocytic leukaemia.
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Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic and molecular study.
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Comprehensive biomarker and genomic analysis identifies p53 status as the major determinant of response to MDM2 inhibitors in chronic lymphocytic leukemia.
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Concurrent acute myeloid leukemia with inv(16)(p13.1q22) and chronic lymphocytic leukemia: molecular evidence of two separate diseases.
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Concurrent classical Hodgkin lymphoma and plasmablastic lymphoma in a patient with chronic lymphocytic leukemia/small lymphocytic lymphoma treated with fludarabine: a dimorphic presentation of iatrogenic immunodeficiency-associated lymphoproliferative disorder with evidence suggestive of multiclonal transformability of B cells by Epstein-Barr virus.
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Cutaneous squamous cell carcinoma in patients with chronic lymphocytic leukemia.
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Detection of trisomy 12 by fluorescence in situ hybridization on archival cytopathologic material in chronic lymphocytic leukemia/small lymphocytic lymphoma.
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Diagnostic and clinical considerations in concomitant bone marrow involvement by plasma cell myeloma and chronic lymphocytic leukemia/monoclonal B-cell lymphocytosis: a series of 15 cases and review of literature.
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Double IGHV DNA gene rearrangements in CLL: influence of mixed-mutated and -unmutated rearrangements on outcomes in CLL.
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Drivers of treatment patterns in patients with chronic lymphocytic leukemia stopping ibrutinib or idelalisib therapies.
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Effect of Azithromycin on Venetoclax Pharmacokinetics in Healthy Volunteers: Implications for Dosing Venetoclax with P-gp Inhibitors.
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Efficacy of bendamustine and rituximab in unfit patients with previously untreated chronic lymphocytic leukemia. Indirect comparison with ibrutinib in a real-world setting. A GIMEMA-ERIC and US study.
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Efficacy of venetoclax plus rituximab for relapsed CLL: 5-year follow-up of continuous or limited- duration therapy.
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Enhanced CDC of B cell chronic lymphocytic leukemia cells mediated by rituximab combined with a novel anti-complement factor H antibody.
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Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cells.
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Epidemiological and mycological characteristics of candidemia in patients with hematological malignancies attending a tertiary-care center in India.
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Epstein-Barr virus DNA load in chronic lymphocytic leukemia is an independent predictor of clinical course and survival.
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Fatal recurrence of autoimmune hemolytic anemia following pentostatin therapy in a patient with a history of fludarabine-associated hemolytic anemia.
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Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53.
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Fludarabine and cyclophosphamide with filgrastim support in patients with previously untreated indolent lymphoid malignancies.
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Fludarabine followed by alemtuzumab consolidation for previously untreated chronic lymphocytic leukemia: final report of Cancer and Leukemia Group B study 19901.
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Frequency and impact of grade three or four toxicities of novel agents on outcomes of older patients with chronic lymphocytic leukemia and non-Hodgkin lymphoma (alliance A151611).
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Fulminant hepatic failure due to disseminated adenovirus infection in a patient with chronic lymphocytic leukemia.
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G-CSF for fever and neutropenia induced by chemotherapy.
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Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia.
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Genetic susceptibility variants for chronic lymphocytic leukemia.
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Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL.
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Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.
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Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.
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Genomic characterization of chronic lymphocytic leukemia (CLL) in radiation-exposed Chornobyl cleanup workers.
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Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia.
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Genomic stratification for the treatment of lymphomas.
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Haematological cancer: Richter's transformation in CLL-a distinct lymphoma.
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Hemolytic anemia after fludarabine therapy for chronic lymphocytic leukemia.
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High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid.
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Highlights from the 46 th annual meeting of the American Society of Hematology.
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Histiocytic/dendritic cell transformation of B-cell neoplasms: pathologic evidence of lineage conversion in differentiated hematolymphoid malignancies.
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Hodgkin lymphoma arising in patients with chronic lymphocytic leukemia: outcomes from a large multi-center collaboration.
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IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria.
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IL-4 and interferon gamma regulate expression of inducible nitric oxide synthase in chronic lymphocytic leukemia cells.
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Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL.
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Ibrutinib plus fludarabine, cyclophosphamide, and rituximab as initial treatment for younger patients with chronic lymphocytic leukaemia: a single-arm, multicentre, phase 2 trial.
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Ibrutinib-Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia.
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Ibrutinib-associated invasive fungal diseases in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: An observational study.
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IgG4-related tubulointerstitial nephritis associated with chronic lymphocytic leukemia.
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Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL.
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Immunoglobulin class switch recombination in chronic lymphocytic leukemia.
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Immunologic aspects of monoclonal B-cell lymphocytosis.
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Immunophenotypic and gene expression analysis of monoclonal B-cell lymphocytosis shows biologic characteristics associated with good prognosis CLL.
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Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14.
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Integrated safety analysis of umbralisib, a dual PI3Kδ/CK1ε inhibitor, in relapsed/refractory lymphoid malignancies.
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Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms.
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In Vivo Expansion and Antitumor Activity of Coinfused CD28- and 4-1BB-Engineered CAR-T Cells in Patients with B Cell Leukemia.
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LMP-420: a novel purine nucleoside analog with potent cytotoxic effects for CLL cells and minimal toxicity for normal hematopoietic cells.
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Lipids and Their Effects in Chronic Lymphocytic Leukemia.
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Lymphoid enhancer binding factor 1 (LEF1) expression is significantly higher in Hodgkin lymphoma associated with Richter syndrome relative to de novo classic Hodgkin lymphoma.
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Malignant (Diffuse) Mesothelioma in Patients With Hematologic Malignancies: A Clinicopathologic Study of 45 Cases.
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Managing toxicities of phosphatidylinositol-3-kinase (PI3K) inhibitors.
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Mantle zone lymphoma in a gastric glomus tumor.
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Mapping of the IRF8 gene identifies a 3'UTR variant associated with risk of chronic lymphocytic leukemia but not other common non-Hodgkin lymphoma subtypes.
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Measurable residual disease does not preclude prolonged progression-free survival in CLL treated with ibrutinib.
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Merkel cell carcinoma with partial B-cell blastic immunophenotype: a potential mimic of cutaneous richter transformation in a patient with chronic lymphocytic lymphoma.
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Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia.
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Metachronous/concomitant B-cell neoplasms with discordant light-chain or heavy-chain isotype restrictions: evidence of distinct B-cell neoplasms rather than clonal evolutions.
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MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference.
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Minimal Residual Disease in Chronic Lymphocytic Leukemia in the Era of Novel Agents: A Review.
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Monoclonal B cell lymphocytosis.
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Monoclonal B cell lymphocytosis: clinical and population perspectives.
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Myeloid neoplasms in the setting of chronic lymphocytic leukaemia/chronic lymphocytic leukaemia-like disease: a clinicopathological study of 66 cases comparing cases with prior history of treatment to those without.
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NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 1.2017.
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NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 2.2019.
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Natural history of monoclonal B-cell lymphocytosis among relatives in CLL families.
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Nitric oxide enhancement of fludarabine cytotoxicity for B-CLL lymphocytes.
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Non-Hodgkin's lymphomas, version 1.2013.
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Ofatumumab monotherapy as a consolidation strategy in patients with previously untreated chronic lymphocytic leukaemia: a phase 2 trial.
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Oligoclonal TRBV gene usage among CD8(+) T cells in monoclonal B lymphocytosis and CLL.
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Optimal sequencing of ibrutinib, idelalisib, and venetoclax in chronic lymphocytic leukemia: results from a multicenter study of 683 patients.
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Outcomes of COVID-19 in patients with CLL: a multicenter international experience.
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Outcomes of front-line ibrutinib treated CLL patients excluded from landmark clinical trial.
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Overexpressed BAG3 is a potential therapeutic target in chronic lymphocytic leukemia.
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Patient-Reported Neuropsychiatric Outcomes of Long-Term Survivors after Chimeric Antigen Receptor T Cell Therapy.
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Patterns of microRNA expression characterize stages of human B-cell differentiation.
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Perifosine as a potential novel anti-telomerase therapy.
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Perifosine treatment in chronic lymphocytic leukemia: results of a phase II clinical trial and in vitro studies.
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Pharmacokinetics of the BCL-2 Inhibitor Venetoclax in Subjects with Hepatic Impairment.
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Phase 2 study of the safety and efficacy of umbralisib in patients with CLL who are intolerant to BTK or PI3Kδ inhibitor therapy.
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Phase I study of low-dose interleukin-2, fludarabine, and cyclophosphamide for previously untreated indolent lymphoma and chronic lymphocytic leukemia.
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Phase II study of cenersen, an antisense inhibitor of p53, in combination with fludarabine, cyclophosphamide and rituximab for high-risk chronic lymphocytic leukemia.
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Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL).
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Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans.
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Post-translational regulation could be determine functional differences between SET alpha and beta isoform - Response to Cristóbal et al.
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Pre-clinical evaluation of SN-38 and novel camptothecin analogs against human chronic B-cell lymphocytic leukemia lymphocytes.
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Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification.
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Progressive outer retinal necrosis.
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Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory chronic lymphocytic leukemia.
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Rationale for combinatory chronic lymphocytic leukaemia treatment paradigms in the era of the B-cell receptor pathway and anti-apoptotic inhibitors: how do we mix, match, and move forward?
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Real-world outcomes and management strategies for venetoclax-treated chronic lymphocytic leukemia patients in the United States.
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Recognizing Unmet Need in the Era of Targeted Therapy for CLL/SLL: "What's Past Is Prologue" (Shakespeare).
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Regulation of leukocyte adhesion molecule-1 (TQ1, Leu-8) expression and shedding by normal and malignant cells.
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Relationship of blood monocytes with chronic lymphocytic leukemia aggressiveness and outcomes: a multi-institutional study.
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Renal lymphoma in an azotemic patient--usefulness of magnetic resonance imaging.
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Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib.
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Richter transformation driven by Epstein-Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukaemia.
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SET alpha and SET beta mRNA isoforms in chronic lymphocytic leukaemia.
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SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target.
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Sequential lymphomas or clonally unrelated richter syndrome of chronic lymphocytic leukemia into mantle cell lymphoma.
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Single nucleotide polymorphisms and inherited risk of chronic lymphocytic leukemia among African Americans.
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Single-cell analysis reveals oligoclonality among 'low-count' monoclonal B-cell lymphocytosis.
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Small lymphocytic lymphoma presenting as a paraneoplastic syndrome with acute central nervous system demyelination.
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Statin use and need for therapy in chronic lymphocytic leukemia.
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Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia.
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Telomerase activity in normal leukocytes and in hematologic malignancies.
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The American College of Surgeons Commission on Cancer and the American Cancer Society. The National Cancer Data Base report on age, gender, treatment, and outcomes of patients with chronic lymphocytic leukemia.
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The Chronic Lymphocytic Leukemia Comorbidity Index (CLL-CI): A Three-Factor Comorbidity Model.
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The efficacy and safety of venetoclax therapy in elderly patients with relapsed, refractory chronic lymphocytic leukaemia.
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The immunologic approach to analysis of malignant lymphoma. Mantle zone lymphoma of the ileocecal region.
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The impact of the host on fungal infections.
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Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells.
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Toxicities and outcomes of 616 ibrutinib-treated patients in the United States: a real-world analysis.
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Toxicity patterns of novel PI3K combinations in patients with non-Hodgkin lymphoma.
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Treatment options for newly diagnosed patients with chronic lymphocytic leukemia.
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Tumor Lysis, Adverse Events, and Dose Adjustments in 297 Venetoclax-Treated CLL Patients in Routine Clinical Practice.
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Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome.
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Ublituximab plus ibrutinib versus ibrutinib alone for patients with relapsed or refractory high-risk chronic lymphocytic leukaemia (GENUINE): a phase 3, multicentre, open-label, randomised trial.
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Umbralisib, a novel PI3Kδ and casein kinase-1ε inhibitor, in relapsed or refractory chronic lymphocytic leukaemia and lymphoma: an open-label, phase 1, dose-escalation, first-in-human study.
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Use of polyethylene glycol-modified uricase (PEG-uricase) to treat hyperuricemia in a patient with non-Hodgkin lymphoma.
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Use of serum-free media to minimize apoptosis of chronic lymphocytic leukemia cells during in vitro culture.
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Value of CD23 determination by flow cytometry in differentiating mantle cell lymphoma from chronic lymphocytic leukemia/small lymphocytic lymphoma.
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Venetoclax for patients with chronic lymphocytic leukemia who progressed during or after idelalisib therapy.
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Venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukaemia: a phase 1b study.
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Virtual bronchoscopy for directing transbronchial needle aspiration of hilar and mediastinal lymph nodes: a pilot study.
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Keywords of People