CD4-Positive T-Lymphocytes

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  Subject Areas on Research

  • A Computational Model of Inhibition of HIV-1 by Interferon-Alpha. 
  • A Possible Sterilizing Cure of HIV-1 Infection Without Stem Cell Transplantation. 
  • A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice. 
  • A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis. 
  • A controlled trial of early versus late treatment with zidovudine in symptomatic human immunodeficiency virus infection. Results of the Veterans Affairs Cooperative Study. 
  • A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection. 
  • A developmental switch from TCR delta enhancer to TCR alpha enhancer function during thymocyte maturation. 
  • A feline immunodeficiency virus vif-deletion mutant remains attenuated upon infection of newborn kittens. 
  • A genetic memory initiates the epigenetic loop necessary to preserve centromere position. 
  • A multicenter trial of oral zidovudine in children with advanced human immunodeficiency virus disease. The Protocol 043 Study Group. 
  • A novel role for type 1 angiotensin receptors on T lymphocytes to limit target organ damage in hypertension. 
  • A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects. 
  • A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma. 
  • A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells. 
  • A soluble inhibitor of T lymphocyte function induced by HIV-1 infection of CD4+ T cells: characterization of a cellular protein and its relationship to p15E. 
  • A trimeric, V2-deleted HIV-1 envelope glycoprotein vaccine elicits potent neutralizing antibodies but limited breadth of neutralization in human volunteers. 
  • A vital role for interleukin-21 in the control of a chronic viral infection. 
  • A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates. 
  • ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis. 
  • ADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection. 
  • AIDS response. 
  • Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses. 
  • Absence of donor MHC antigen expression ameliorates chronic kidney allograft rejection. 
  • Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens. 
  • Activated T lymphocytes regulate hyaluronan binding to monocyte CD44 via production of IL-2 and IFN-gamma. 
  • Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis. 
  • Activation of tat-defective human immunodeficiency virus by ultraviolet light. 
  • Acute HIV Infection and CD4/CD8 Ratio Normalization After Antiretroviral Therapy Initiation. 
  • Acute IL-4 Governs Pathogenic T Cell Responses during Leishmania major Infection. 
  • Acute and chronic B cell depletion disrupts CD4+ and CD8+ T cell homeostasis and expansion during acute viral infection in mice. 
  • Adaptive immune responses to primary and secondary dengue virus infections. 
  • Adjuvanting a subunit COVID-19 vaccine to induce protective immunity. 
  • Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients. 
  • Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. 
  • Age-related variations in the methylome associated with gene expression in human monocytes and T cells. 
  • Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity. 
  • Alemtuzumab in the treatment of refractory acute rejection and bronchiolitis obliterans syndrome after human lung transplantation. 
  • Allospecific CD4(+) effector memory T cells do not induce graft-versus-host disease in mice. 
  • Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques. 
  • Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients. 
  • Altered intragraft immune responses and improved renal function in MHC class II-deficient mouse kidney allografts. 
  • Amplification of suppressor inducer pathway with monoclonal antibody, anti-2H4, identifying a novel epitope of the common leukocyte antigen/T200 antigen. 
  • An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum. 
  • An analysis of alternatively spliced CD45 mRNA transcripts during T cell maturation in humans. 
  • An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants. 
  • An essential role for c-FLIP in the efficient development of mature T lymphocytes. 
  • Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins. 
  • Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection. 
  • Analysis of the immune responses in chimpanzees infected with HIV type 1 isolates. 
  • Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model. 
  • Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines. 
  • Antibodies against retroviral proteins and nuclear antigens in a subset of idiopathic CD4+ T lymphocytopenia patients. 
  • Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial. 
  • Antibody Fab-Fc properties outperform titer in predictive models of SIV vaccine-induced protection. 
  • Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia. 
  • Antibody-Dependent Cellular Cytotoxicity (ADCC)-Mediating Antibodies Constrain Neutralizing Antibody Escape Pathway. 
  • Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development. 
  • Antigen-specific induced Foxp3+ regulatory T cells are generated following CD40/CD154 blockade. 
  • Antigenicity and Immunogenicity of HIV-1 Envelope Trimers Complexed to a Small-Molecule Viral Entry Inhibitor. 
  • Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection. 
  • Antiretroviral therapy corrects HIV-1-induced expansion of CD8+ CD45RA+ CD2-) CD11a(bright) activated T cells. 
  • Antiretroviral therapy restores diversity in the T-cell receptor Vbeta repertoire of CD4 T-cell subpopulations among human immunodeficiency virus type 1-infected children and adolescents. 
  • Association of CD8(+) T lymphocyte repertoire spreading with the severity of DRESS syndrome. 
  • Astrocyte cytolysis by MHC class II-specific mouse T cell clones. 
  • Augmentation of human immunodeficiency virus type 1 neutralizing antibody by priming with gp160 recombinant vaccinia and boosting with rgp160 in vaccinia-naive adults. The NIAID AIDS Vaccine Clinical Trials Network. 
  • Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes. 
  • B cells are required for optimal CD4+ and CD8+ T cell tumor immunity: therapeutic B cell depletion enhances B16 melanoma growth in mice. 
  • B-lymphocyte contributions to human autoimmune disease. 
  • Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection. 
  • Beta-arrestin-2 regulates the development of allergic asthma. 
  • Biochemical and immunological abnormalities in purine nucleoside phosphorylase deficient mice. 
  • Brief Report: Relationship Between Nonalcoholic Fatty Liver Disease and Cardiovascular Disease in Persons With HIV. 
  • CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cells. 
  • CD169-dependent cell-associated HIV-1 transmission: a driver of virus dissemination. 
  • CD19 expression in B cells is important for suppression of contact hypersensitivity. 
  • CD19 expression in B cells regulates atopic dermatitis in a mouse model. 
  • CD4 T cells differentially express cellular machinery for serotonin signaling, synthesis, and metabolism. 
  • CD4 T-Cell Exhaustion: Does It Exist and What Are Its Roles in Cancer? 
  • CD4 mimetics sensitize HIV-1-infected cells to ADCC. 
  • CD4 receptor diversity in chimpanzees protects against SIV infection. 
  • CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation. 
  • CD4+ CD25+ FOXP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with Campath-1H. 
  • CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells. 
  • CD4+ T-cell and monocyte interdependence during discordant xenoimmune responses. 
  • CD4+ T-cell-guided structured treatment interruptions of antiretroviral therapy in HIV disease: projecting beyond clinical trials. 
  • CD4+ and viral load outcomes of antiretroviral therapy switch strategies after virologic failure of combination antiretroviral therapy in perinatally HIV-infected youth in the United States. 
  • CD4+ lymphocyte response to zidovudine as a predictor of AIDS-free time and survival time. 
  • CD4+ memory T cells are the predominant population of HIV-1-infected lymphocytes in neonates and children. 
  • CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury. 
  • CD4+CD45RBHi T cell transfer induced colitis in mice is accompanied by osteopenia which is treatable with recombinant human osteoprotegerin. 
  • CD4+Thy1- thymocytes with a Th-type 2 cytokine response. 
  • CD4/CD8 double negative pagetoid reticulosis: a case report and literature review. 
  • CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis. 
  • CD40L-adjuvanted DNA/modified vaccinia virus Ankara simian immunodeficiency virus SIV239 vaccine enhances SIV-specific humoral and cellular immunity and improves protection against a heterologous SIVE660 mucosal challenge. 
  • CD57(+) CD4 T Cells Underlie Belatacept-Resistant Allograft Rejection. 
  • CD7 and CD28 are required for murine CD4+CD25+ regulatory T cell homeostasis and prevention of thyroiditis. 
  • CD8+ cell lines isolated from HIV-1-infected children have potent soluble HIV-1 inhibitory activity that differs from beta-chemokines. 
  • CD8+ lymphocyte activation at human immunodeficiency virus type 1 seroconversion: development of HLA-DR+ CD38- CD8+ cells is associated with subsequent stable CD4+ cell levels. The Multicenter AIDS Cohort Study Group. 
  • CD83 expression influences CD4+ T cell development in the thymus. 
  • CD83 expression is a sensitive marker of activation required for B cell and CD4+ T cell longevity in vivo. 
  • CD83: a regulatory molecule of the immune system with great potential for therapeutic application. 
  • CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. 
  • CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells. 
  • CTLA-4-Mediated inhibition of early events of T cell proliferation. 
  • CX(3)CR1 drives cytotoxic CD4(+)CD28(-) T cells into the brain of multiple sclerosis patients. 
  • CXCL12 prolongs naive CD4+ T lymphocytes survival via activation of PKA, CREB and Bcl2 and BclXl up-regulation. 
  • Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action. 
  • Cell-based vaccines for the stimulation of immunity to metastatic cancers. 
  • Cervical dysplasia in women infected with the human immunodeficiency virus (HIV): a correlation with HIV viral load and CD4+ count. 
  • Changes in CD4+ T-cell differentiation phenotype during structured treatment interruption in patients with chronic HIV-1 infection. 
  • Changes in T and non-T lymphocyte subsets following seroconversion to HIV-1: stable CD3+ and declining CD3- populations suggest regulatory responses linked to loss of CD4 lymphocytes. The Multicenter AIDS Cohort Study. 
  • Changes in thymic function with age and during the treatment of HIV infection. 
  • Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection. 
  • Characterization of the innate immune response to chronic aspiration in a novel rodent model. 
  • Chlamydia trachomatis Infection of Endocervical Epithelial Cells Enhances Early HIV Transmission Events. 
  • Chronic graft-versus-host disease. 
  • Chronic multifocal retinal infiltrates in patients infected with human immunodeficiency virus. 
  • Circulating CXCR5+PD-1+ response predicts influenza vaccine antibody responses in young adults but not elderly adults. 
  • Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers. 
  • Clinical and laboratory correlates of Pneumocystis carinii pneumonia in children infected with HIV. 
  • Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4+ T cells. 
  • Coadministration of zidovudine and interleukin-2 increases absolute CD4 cells in subjects with Walter Reed stage 2 human immunodeficiency virus infection: results of ACTG protocol 042. 
  • Cocaine dependence does not contribute substantially to white matter abnormalities in HIV infection. 
  • Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. 
  • Combined CD4 T-cell and antibody response to human minor histocompatibility antigen DBY after allogeneic stem-cell transplantation. 
  • Combined immunodeficiency due to the selective absence of CD4 inducer T lymphocytes. 
  • Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells. 
  • Comparative ability of plasmid IL-12 and IL-15 to enhance cellular and humoral immune responses elicited by a SIVgag plasmid DNA vaccine and alter disease progression following SHIV(89.6P) challenge in rhesus macaques. 
  • Comparative evaluation of simian, simian-human, and human immunodeficiency virus infections in the pigtail macaque (Macaca nemestrina) model. 
  • Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVAC, and Envelope Protein Boost. 
  • Comparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV. 
  • Comparison of systemic and mucosal vaccination: impact on intravenous and rectal SIV challenge. 
  • Comparison of vaccine strategies using recombinant env-gag-pol MVA with or without an oligomeric Env protein boost in the SHIV rhesus macaque model. 
  • Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections. 
  • Complement and CD4+ T cells drive context-specific corneal sensory neuropathy. 
  • Concerning the article by de Carvalho Bittencourt et al.: Value of HIV patients with regular follow-up as in-house internal controls of flow cytometry measurement of lymphocyte subsets. 
  • Conjugates of betulin derivatives with AZT as potent anti-HIV agents. 
  • Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals. 
  • Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses. 
  • Contemporary Strategies and Barriers to Transplantation Tolerance. 
  • Continuous improvement in the immune system of HIV-infected children on prolonged antiretroviral therapy. 
  • Contribution of IL-13 to early exocrinopathy in Id3-/- mice. 
  • Contributions of E1A to mouse adenovirus type 1 pathogenesis following intranasal inoculation. 
  • Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. 
  • Control of viremia and maintenance of intestinal CD4(+) memory T cells in SHIV(162P3) infected macaques after pathogenic SIV(MAC251) challenge. 
  • Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination. 
  • Conversion of effector CD4+ T cells to a CD8+ MHC II-recognizing lineage. 
  • Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model. 
  • Correlates of nontransmission in US women at high risk of human immunodeficiency virus type 1 infection through sexual exposure. 
  • Correlating notch signaling with thymocyte maturation. 
  • Corticosteroids improve survival of children with AIDS and Pneumocystis carinii pneumonia. 
  • Costimulation blockade alters germinal center responses and prevents antibody-mediated rejection. 
  • Costimulator dependence of lymphokine secretion by naive and activated CD4+ T lymphocytes from TCR transgenic mice. 
  • Critical issues in mucosal immunity for HIV-1 vaccine development. 
  • Critical role for Env as well as Gag-Pol in control of a simian-human immunodeficiency virus 89.6P challenge by a DNA prime/recombinant modified vaccinia virus Ankara vaccine. 
  • Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promoting MHC class II expression via IRF4 and CIITA. 
  • Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques. 
  • Cross-clade inhibition of HIV-1 replication and cytopathology by using RNase P-associated external guide sequences. 
  • Cross-reactivity of HIV vaccine responses and the microbiome. 
  • Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. 
  • Cytokine transcriptional events during helper T cell subset differentiation. 
  • Cytomegalovirus retinitis in HIV-infected patients with elevated CD4+ counts. 
  • DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial. 
  • DNA-MVA vaccine protection after X4 SHIV challenge in macaques correlates with day-of-challenge antiviral CD4+ cell-mediated immunity levels and postchallenge preservation of CD4+ T cell memory. 
  • Decreasing CD4+ T-cell count during suppressed or low-level viraemia in patients with HIV infection. 
  • Defective dendritic cell maturation in a child with nucleotide excision repair deficiency and CD4 lymphopenia. 
  • Defective signaling in a subpopulation of CD4(+) T cells in the absence of Ca(2+)/calmodulin-dependent protein kinase IV. 
  • Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis. 
  • Deficient antibody-dependent cellular cytotoxicity against human immunodeficiency virus (HIV)-expressing target cells in perinatal HIV infection. 
  • Delayed-type hypersensitivity skin tests are an independent predictor of human immunodeficiency virus disease progression. Department of Veterans Affairs Cooperative Study Group. 
  • Dendritic Cell Immunotherapy for HIV-1 Infection Using Autologous HIV-1 RNA: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. 
  • Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta. 
  • Detailed analysis of gene expression during development of T cell lineages in the thymus. 
  • Detection of HIV-1 neutralizing antibodies in a human CD4⁺/CXCR4⁺/CCR5⁺ T-lymphoblastoid cell assay system. 
  • Determination of CD4 and CD8 lymphocyte subsets by a new alternative fluorescence immunoassay. 
  • Development of a tier 1 R5 clade C simian-human immunodeficiency virus as a tool to test neutralizing antibody-based immunoprophylaxis. 
  • Developmental regulation of P-glycoprotein activity within thymocytes results in increased anti-HIV protease inhibitor activity. 
  • Developmental regulation of alpha beta T cell antigen receptor expression results from differential stability of nascent TCR alpha proteins within the endoplasmic reticulum of immature and mature T cells. 
  • Differences in HIV-specific T cell responses between HIV-exposed and -unexposed HIV-seronegative individuals. 
  • Differences in intraepithelial lymphocyte T cell subsets isolated from murine small versus large intestine. 
  • Different patterns of immune responses but similar control of a simian-human immunodeficiency virus 89.6P mucosal challenge by modified vaccinia virus Ankara (MVA) and DNA/MVA vaccines. 
  • Differential CMV-specific CD8+ effector T cell responses in the lung allograft predominate over the blood during human primary infection. 
  • Differential inhibition of HIV-1 cell binding and HIV-1-induced syncytium formation by low molecular weight sulphated polysaccharides. 
  • Differentiation and tolerance of CD4+ T lymphocytes. 
  • Disruption of intrathymic CD4-Ia interactions on immature CD4+CD8+ thymocytes results in diminished TCR expression on mature CD8+ T cell progeny. 
  • Distinct CD4+ helper T cells involved in primary and secondary responses to infection. 
  • Distinct kinetics of Gag-specific CD4+ and CD8+ T cell responses during acute HIV-1 infection. 
  • Ditiocarb sodium (diethyldithiocarbamate) therapy in patients with symptomatic HIV infection and AIDS. A randomized, double-blind, placebo-controlled, multicenter study. 
  • Divergent Roles of Epithelium-Derived Alarmins in Notch Signaling-Deficient Skin. 
  • Donor Allospecific CD44high Central Memory T Cells Have Decreased Ability to Mediate Graft-vs.-Host Disease. 
  • Donor-specific CD8+ Foxp3+ T cells protect skin allografts and facilitate induction of conventional CD4+ Foxp3+ regulatory T cells. 
  • Downregulation of the AU-rich RNA-binding protein ZFP36 in chronic HBV patients: implications for anti-inflammatory therapy. 
  • Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity. 
  • Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells. 
  • E protein transcription factors are required for the development of CD4(+) lineage T cells. 
  • ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms. 
  • EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells. 
  • Early, sustained efficacy of adeno-associated virus vector-mediated gene therapy in glycogen storage disease type Ia. 
  • Editorial: Viral Infection at the Maternal-Fetal Interface. 
  • Effect of Alemtuzumab (CAMPATH 1-H) in patients with inclusion-body myositis. 
  • Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice. 
  • Effect of complement consumption by cobra venom factor on the course of primary infection with simian immunodeficiency virus in rhesus monkeys. 
  • Effect of host factors and COVID-19 infection on the humoral immune repertoire in treated HIV. 
  • Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling. 
  • Effect of influenza virus vaccine on the expression of human immunodeficiency virus co-receptor CCR5. 
  • Effect of pregnancy and human immunodeficiency virus infection on intracellular interleukin-2 production patterns. 
  • Effect of thymectomy on human peripheral blood T cell pools in myasthenia gravis. 
  • Effect of zidovudine and Pneumocystis carinii pneumonia prophylaxis on progression of HIV-1 infection to AIDS. The Multicenter AIDS Cohort Study. 
  • Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new. 
  • Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection. 
  • Effects of human immunodeficiency virus type 1 infection on CCR5 and CXCR4 coreceptor expression on CD4 T lymphocyte subsets in infants and adolescents. 
  • Effects of human immunodeficiency virus type 1 on CD4 lymphocyte subset activation. 
  • Efficacy of DNA and fowlpox virus priming/boosting vaccines for simian/human immunodeficiency virus. 
  • Efficient Culture of Human Naive and Memory B Cells for Use as APCs. 
  • Efficient dendritic cell priming of T lymphocytes depends on the extracellular matrix protein mindin. 
  • Electron tomography of the contact between T cells and SIV/HIV-1: implications for viral entry. 
  • Elevated CD4+/CD25+ T cell frequency and function during acute hepatitis C presage chronic evolution. 
  • Elevated serum L-selectin levels and abnormal regulation of L-selectin expression on leukocytes in atopic dermatitis: soluble L-selectin levels indicate disease severity. 
  • Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif. 
  • Emergence of simian immunodeficiency virus-specific cytotoxic CD4+ T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency virus. 
  • Ena/VASP proteins regulate activated T-cell trafficking by promoting diapedesis during transendothelial migration. 
  • Enfuvirtide: the first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes. 
  • Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein. 
  • Enhanced allergen-induced airway inflammation in paucity of lymph node T cell (plt) mutant mice. 
  • Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. 
  • Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus. 
  • Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene Expression. 
  • Escape from tolerance in the human X-linked autoimmunity-allergic disregulation syndrome and the Scurfy mouse. 
  • Establishment of haematological and immunological reference values for healthy Tanzanian children in Kilimanjaro Region. 
  • Establishment, Persistence, and Reactivation of Latent HIV-1 Infection in Renal Epithelial Cells. 
  • Ethical dilemmas in continuing a zidovudine trial after early termination of similar trials. 
  • Ethylenecarbodiimide-treated splenocytes carrying male CD4 epitopes confer histocompatibility Y chromosome antigen transplant protection by inhibiting CD154 upregulation. 
  • Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays. 
  • Evaluation of CD86/CD28 and CD40/CD154 pathways in regulating monocyte-derived CD80 expression during their interaction with allogeneic endothelium. 
  • Evaluation of a method for counting absolute numbers of cells with a flow cytometer. 
  • Evaluation of host immune responses to pulmonary cryptococcosis using a temperature-sensitive C. neoformans calcineurin A mutant strain. 
  • Evaluation of humoral, mucosal, and cellular immune responses following co-immunization of HIV-1 Gag and Env proteins expressed by Newcastle disease virus. 
  • Evaluation of the blood stabilizers TransFix and Cyto-Chex BCT for low-cost CD4 T-cell methodologies. 
  • Evidence for susceptibility of intrathymic T cell precursors to human immunodeficiency virus infection: a mechanism for T4 (CD4) lymphocyte depletion. 
  • Exploiting Pre-Existing CD4+ T Cell Help from Bacille Calmette-Guérin Vaccination to Improve Antiviral Antibody Responses. 
  • Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid. 
  • Extranodal lymphoid microstructures in inflamed muscle and disease severity of new-onset juvenile dermatomyositis. 
  • Failure of T-cell homeostasis preceding AIDS in HIV-1 infection. The Multicenter AIDS Cohort Study. 
  • Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans. 
  • Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site. 
  • Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells. 
  • Follicular mucinosis as a presenting sign of acute myeloblastic leukemia. 
  • Functional Characteristics and Phenotypic Plasticity of CD57+PD1- CD4 T Cells and Their Relationship with Transplant Immunosuppression. 
  • Functional characteristics and survival requirements of memory CD4+ T lymphocytes in vivo. 
  • Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion. 
  • G-CSF induces a potentially tolerant gene and immunophenotype profile in T cells in vivo. 
  • Gene Therapy for Modulation of T-Cell-Mediated Immune Response Provoked by Corneal Transplantation. 
  • Gene targeting: applications in transplantation research. 
  • Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophages. 
  • Genetic deficiency of Irgm1 (LRG-47) suppresses induction of experimental autoimmune encephalomyelitis by promoting apoptosis of activated CD4+ T cells. 
  • Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. 
  • Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination. 
  • Glimpse of natural selection of long-lived T-cell clones in healthy life. 
  • Glucose-regulated protein 94/glycoprotein 96 elicits bystander activation of CD4+ T cell Th1 cytokine production in vivo. 
  • Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help. 
  • Glycosylated recombinant human XCL1/lymphotactin exhibits enhanced biologic activity. 
  • Gnidimacrin, a Potent Anti-HIV Diterpene, Can Eliminate Latent HIV-1 Ex Vivo by Activation of Protein Kinase C β. 
  • Growth as a prognostic indicator in children with human immunodeficiency virus infection treated with zidovudine. AIDS Clinical Trials Group Protocol 043 Study Group. 
  • Growth failure and AIDS-like cachexia syndrome in HIV-1 transgenic mice. 
  • HIV immunization. Fresh pathways to follow. 
  • HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response. 
  • HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition. 
  • HIV-1 gp120 and Modified Vaccinia Virus Ankara (MVA) gp140 Boost Immunogens Increase Immunogenicity of a DNA/MVA HIV-1 Vaccine. 
  • HIV-1 gp120 induces anergy in naive T lymphocytes through CD4-independent protein kinase-A-mediated signaling. 
  • HIV-1 reservoir evolution in infants infected with clade C from Mozambique. 
  • HIV-1 resistance to CCR5 antagonists associated with highly efficient use of CCR5 and altered tropism on primary CD4+ T cells. 
  • HIV-1 sensitivity to zidovudine and clinical outcome in children. 
  • HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes. 
  • HIV. A clever hijacker of the immune system. 
  • HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-Specific B and T Cell Immune Functions in Nonhuman Primates. 
  • HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers. 
  • Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. 
  • Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors. 
  • High level expression of CD43 inhibits T cell receptor/CD3-mediated apoptosis. 
  • High-quality CMV-specific CD4+ memory is enriched in the lung allograft and is associated with mucosal viral control. 
  • High-resolution mapping and characterization of open chromatin across the genome. 
  • Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity. 
  • Human Immunodeficiency Virus C.1086 Envelope gp140 Protein Boosts following DNA/Modified Vaccinia Virus Ankara Vaccination Fail To Enhance Heterologous Anti-V1V2 Antibody Response and Protection against Clade C Simian-Human Immunodeficiency Virus Challenge. 
  • Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques. 
  • Human dendritic cells, pulsed with either melanoma tumor cell lysates or the gp100 peptide(280-288), induce pairs of T-cell cultures with similar phenotype and lytic activity. 
  • Human gut microbiota is associated with HIV-reactive immunoglobulin at baseline and following HIV vaccination. 
  • Human immunodeficiency virus type 1 (HIV-1) induces activation of multiple STATs in CD4+ cells of lymphocyte or monocyte/macrophage lineages. 
  • Human immunodeficiency virus type 1 infection despite prior immunization with a recombinant envelope vaccine regimen. 
  • Human immunodeficiency virus type 1-specific cytotoxic T lymphocyte activity is inversely correlated with HIV type 1 viral load in HIV type 1-infected long-term survivors. 
  • Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. 
  • Humoral Immune Reconstitution Kinetics after Allogeneic Hematopoietic Stem Cell Transplantation in Children: A Maturation Block of IgM Memory B Cells May Lead to Impaired Antibody Immune Reconstitution. 
  • Hyperinflammation, T cells, and endotoxemia. 
  • Hypervariable region 1 variant acting as TCR antagonist affects hepatitis C virus-specific CD4+ T cell repertoire by favoring CD95-mediated apoptosis. 
  • IFN-beta inhibits human Th17 cell differentiation. 
  • IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis. 
  • IL-11 in multiple sclerosis. 
  • IL-12-Dependent Cytomegalovirus-Specific CD4+ T Cell Proliferation, T-bet Induction, and Effector Multifunction during Primary Infection Are Key Determinants for Early Immune Control. 
  • IL-15 expanded CD8+CD122+ cells: when do they suppress? 
  • IL-17 contributes to neutrophil recruitment but not to control of viral replication during acute mouse adenovirus type 1 respiratory infection. 
  • IL-2-dependent adaptive control of NK cell homeostasis. 
  • IL-2-induced CD4+ T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation. 
  • IL-21 deficiency influences CD8 T cell quality and recall responses following an acute viral infection. 
  • IL-4 induces differentiation and expansion of Th2 cytokine-producing eosinophils. 
  • Identification and characterization of an agonistic aptamer against the T cell costimulatory receptor, OX40. 
  • Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. 
  • Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma. 
  • Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites. 
  • Immune Activation in Early-Stage Non-Small Cell Lung Cancer Patients Receiving Neoadjuvant Chemotherapy Plus Ipilimumab. 
  • Immune Reconstitution but Persistent Activation After 48 Weeks of Antiretroviral Therapy in Youth With Pre-Therapy CD4 >350 in ATN 061. 
  • Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. 
  • Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. 
  • Immune correlates of HIV-1 reservoir cell decline in early-treated infants. 
  • Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates. 
  • Immune correlates of vaccine protection against HIV-1 acquisition. 
  • Immune failure in the absence of profound CD4+ T-lymphocyte depletion in simian immunodeficiency virus-infected rapid progressor macaques. 
  • Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection. 
  • Immune reconstitution in human immunodeficiency virus-infected children receiving highly active antiretroviral therapy: a cohort study. 
  • Immune reconstitution inflammatory syndrome involving the central nervous system in a patient with HIV infection: a case report and review of literature. 
  • Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239. 
  • Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates. 
  • Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion. 
  • Immunogenicity in macaques of the clinical product for a clade B DNA/MVA HIV vaccine: elicitation of IFN-gamma, IL-2, and TNF-alpha coproducing CD4 and CD8 T cells. 
  • Immunogenicity of AGS-004 Dendritic Cell Therapy in Patients Treated During Acute HIV Infection. 
  • Immunogenicity study of glycoprotein-deficient rabies virus expressing simian/human immunodeficiency virus SHIV89.6P envelope in a rhesus macaque. 
  • Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies. 
  • Immunologic and virologic analyses of an acutely HIV type 1-infected patient with extremely rapid disease progression. 
  • Immunologic profile of human immunodeficiency virus-infected patients during viral remission and relapse on antiretroviral therapy. 
  • Immunologic reconstitution during PEG-ADA therapy in an unusual mosaic ADA deficient patient. 
  • Immunologic targets of HIV infection: T cells. NICHD IVIG Clinical Trial Group, and the NHLBI P2C2 Pediatric Pulmonary and Cardiac Complications of HIV Infection Study Group. 
  • Immunological memory induced by genetically transduced tumor cells. 
  • Immunomagnetic selection of purified monocyte and lymphocyte populations from peripheral blood mononuclear cells following cryopreservation. 
  • Immunoreconstitution after ritonavir therapy in children with human immunodeficiency virus infection involves multiple lymphocyte lineages. 
  • Impact of HIV-1 backbone on neutralization sensitivity: neutralization profiles of heterologous envelope glycoproteins expressed in native subtype C and CRF01_AE backbone. 
  • Impact of Simian Immunodeficiency Virus Infection on Chimpanzee Population Dynamics. 
  • Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome. 
  • Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5. 
  • Improved killing of HIV-infected cells using three neutralizing and non-neutralizing antibodies. 
  • In Vitro Differentiation of CD4+ T Cell Effector and Regulatory Subsets. 
  • In utero priming of highly functional effector T cell responses to human malaria. 
  • In vivo downregulation of innate and adaptive immune responses in corneal allograft rejection by HC-HA/PTX3 complex purified from amniotic membrane. 
  • In vivo expansion, persistence, and function of peptide vaccine-induced CD8 T cells occur independently of CD4 T cells. 
  • In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms. 
  • Inability of memory T cells to induce graft-versus-host disease is a result of an abortive alloresponse. 
  • Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. 
  • Increased circulating interleukin-7 levels in HIV-1-infected women. 
  • Increased loss of CCR5+ CD45RA- CD4+ T cells in CD8+ lymphocyte-depleted Simian immunodeficiency virus-infected rhesus monkeys. 
  • Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz. 
  • Increased proportion of FoxP3+ regulatory T cells in tumor infiltrating lymphocytes is associated with tumor recurrence and reduced survival in patients with glioblastoma. 
  • Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma. 
  • Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: implication for cancer immunotherapy. 
  • Induction of human immunodeficiency virus type 1 (HIV-1)-specific cytolytic T lymphocyte responses in seronegative adults by a nonreplicating, host-range-restricted canarypox vector (ALVAC) carrying the HIV-1MN env gene. 
  • Infectious morbidity in long-term survivors of allogeneic marrow transplantation is associated with low CD4 T cell counts. 
  • Influence of CD4 T cells and the source of major histocompatibility complex class II-restricted peptides on cytotoxic T-cell priming by dendritic cells. 
  • Influence of host genotype on progression to acquired immunodeficiency syndrome among children infected with human immunodeficiency virus type 1. 
  • Inhibition of invariant chain expression in dendritic cells presenting endogenous antigens stimulates CD4+ T-cell responses and tumor immunity. 
  • Inhibitory effect of PRO 2000, a candidate microbicide, on dendritic cell-mediated human immunodeficiency virus transfer. 
  • Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. 
  • Innate immune activation by the viral PAMP poly I:C potentiates pulmonary graft-versus-host disease after allogeneic hematopoietic cell transplant. 
  • Innate immune signatures to a partially-efficacious HIV vaccine predict correlates of HIV-1 infection risk. 
  • Integrin functions play a key role in the differentiation of thymocytes in vivo. 
  • Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity. 
  • Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon. 
  • Interferon-alpha with zidovudine: safety, tolerance, and clinical and virologic effects in patients with Kaposi sarcoma associated with the acquired immunodeficiency syndrome (AIDS). 
  • Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169. 
  • Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome. 
  • Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo. 
  • Interleukin-28B gene polymorphisms do not influence the susceptibility to HIV-infection or CD4 cell decline. 
  • Interplay between Immune and Airway Smooth Muscle Cells in Obese Asthma. 
  • Intravitreal sustained-release cyclosporine in the treatment of experimental uveitis. 
  • Irgm1 regulates metabolism and function in T cell subsets. 
  • JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation. 
  • LAT-mediated signaling in CD4+CD25+ regulatory T cell development. 
  • Laboratory Accuracy Improvement in the UK NEQAS Leucocyte Immunophenotyping Immune Monitoring Program: An Eleven-Year Review via Longitudinal Mixed Effects Modeling. 
  • Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans. 
  • Lessons learned from HIV-1 vaccine trials: new priorities and directions. 
  • Long term disease-free survival and T cell and antibody responses in women with high-risk Her2+ breast cancer following vaccination against Her2. 
  • Long-term effects of intermittent interleukin 2 therapy in patients with HIV infection: characterization of a novel subset of CD4(+)/CD25(+) T cells. 
  • Long-term follow-up of symptomatic HIV-infected patients originally randomized to early versus later zidovudine treatment; report of a Veterans Affairs Cooperative Study. VA Cooperative Study Group on AIDS Treatment. 
  • Loss of tolerance of anti-dsDNA B cells in mice overexpressing CD19. 
  • Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. 
  • Lung effector memory and activated CD4+ T cells display enhanced proliferation in surfactant protein A-deficient mice during allergen-mediated inflammation. 
  • Lymphocyte subsets in healthy children during the first 5 years of life. 
  • Lyphocyte migration in L-selectin-deficient mice. Altered subset migration and aging of the immune system. 
  • MEKK3 is essential for lymphopenia-induced T cell proliferation and survival. 
  • Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions. 
  • Massive CD8 T cell response to primary HIV infection in the setting of severe clinical presentation. 
  • Mast cells impair the development of protective anti-tumor immunity. 
  • Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission. 
  • MeCP2 reinforces STAT3 signaling and the generation of effector CD4+ T cells by promoting miR-124-mediated suppression of SOCS5. 
  • Mechanism of pokeweed mitogen inhibition of rhIL-4-induced human IgE synthesis. 
  • Mechanisms of tolerance induced by PG490-88 in a bone marrow transplantation model. 
  • Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation. 
  • Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. 
  • Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. 
  • Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice. 
  • MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice. 
  • MicroRNA-23a Curbs Necrosis during Early T Cell Activation by Enforcing Intracellular Reactive Oxygen Species Equilibrium. 
  • Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice. 
  • Modelling HIV immune response and validation with clinical data. 
  • Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of IL15. 
  • Modulation of CD45 tyrosine phosphatase activity by antigen. 
  • Modulation of murine herpes simplex virus type 1 retinitis in the uninoculated eye by CD4+ T lymphocytes. 
  • Molecular analysis of highly enriched populations of T-cell-depleted monocytes. 
  • Monocytes prime autoreactive T cells after myocardial infarction. 
  • Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys. 
  • Mucosal co-infections and HIV-1 transmission and pathogenesis. 
  • Mucosal human defensins 5 and 6 antagonize the anti-HIV activity of candidate polyanion microbicides. 
  • Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response. 
  • Multivalent benzoboroxole functionalized polymers as gp120 glycan targeted microbicide entry inhibitors. 
  • Murine dendritic cells transfected with human GP100 elicit both antigen-specific CD8(+) and CD4(+) T-cell responses and are more effective than DNA vaccines at generating anti-tumor immunity. 
  • Murine leptin deficiency alters Kupffer cell production of cytokines that regulate the innate immune system. 
  • Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression. 
  • Mycobacterium bovis bacille Calmette-Guérin infection in the CNS suppresses experimental autoimmune encephalomyelitis and Th17 responses in an IFN-gamma-independent manner. 
  • Mycophenolate mofetil suppresses autoimmunity and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus. 
  • NLRC3 expression in dendritic cells attenuates CD4+ T cell response and autoimmunity. 
  • NLRC3 negatively regulates CD4+ T cells and impacts protective immunity during Mycobacterium tuberculosis infection. 
  • Nasal DNA-MVA SIV vaccination provides more significant protection from progression to AIDS than a similar intramuscular vaccination. 
  • Nasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury. 
  • Natural Killer Cells Regulate Acute SIV Replication, Dissemination, and Inflammation, but Do Not Impact Independent Transmission Events. 
  • Naïve T cells are maintained in the periphery during the first 3 months of acute HIV-1 infection: implications for analysis of thymus function. 
  • Nef expressed from human immunodeficiency virus type 1 extrachromosomal DNA downregulates CD4 on primary CD4+ T lymphocytes: implications for integrase inhibitors. 
  • Neisseria gonorrhoeae enhances HIV-1 infection of primary resting CD4+ T cells through TLR2 activation. 
  • Neisseria gonorrhoeae-induced human defensins 5 and 6 increase HIV infectivity: role in enhanced transmission. 
  • Neutralizing antibodies to HIV-1 in seronegative volunteers immunized with recombinant gp120 from the MN strain of HIV-1. NIAID AIDS Vaccine Clinical Trials Network. 
  • Normal interleukin-7 (IL7) levels and normal IL7 response to CD4 T lymphopenia in patients with multiple sclerosis and systemic sclerosis. 
  • Nucleoside-analogue reverse-transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir for pretreated children infected with human immunodeficiency virus type 1. 
  • Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1. 
  • Optimization of a highly standardized carboxyfluorescein succinimidyl ester flow cytometry panel and gating strategy design using discriminative information measure evaluation. 
  • Outer Membrane Vesicles Displaying a Heterologous PcrV-HitA Fusion Antigen Promote Protection against Pulmonary Pseudomonas aeruginosa Infection. 
  • Overview of melanoma vaccines and promising approaches. 
  • PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation. 
  • Partial protection of Simian immunodeficiency virus (SIV)-infected rhesus monkeys against superinfection with a heterologous SIV isolate. 
  • Partial resistance to infection by R5X4 primary HIV type 1 isolates in an exposed-uninfected individual homozygous for CCR5 32-base pair deletion. 
  • Passive infusion of immune serum into simian immunodeficiency virus-infected rhesus macaques undergoing a rapid disease course has minimal effect on plasma viremia. 
  • Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-γ+CD4+ T cell numbers during colitis development in mice. 
  • Pharmacovirological impact of an integrase inhibitor on human immunodeficiency virus type 1 cDNA species in vivo. 
  • Phase 1 clinical trials of the National Institutes of Health Vaccine Research Center HIV/AIDS candidate vaccines. 
  • Phase 1 safety and immunogenicity testing of DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles. 
  • Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial. 
  • Phenotypic Correlates of HIV-1 Macrophage Tropism. 
  • Phenotypic and immunologic comparison of clade B transmitted/founder and chronic HIV-1 envelope glycoproteins. 
  • Phenotypic properties of transmitted founder HIV-1. 
  • Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages. 
  • Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses. 
  • Polychromatic plots: graphical display of multidimensional data. 
  • Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys. 
  • Postintegration HIV-1 infection of cervical epithelial cells mediates contact-dependent productive infection of T cells. 
  • Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. 
  • Posttraumatic lymphocyte response: a comparison between peripheral blood T cells and tissue T cells. 
  • Potent inhibition of human immunodeficiency virus type 1 (HIV-1) replication by inducible expression of HIV-1 PR multimers. 
  • Preclinical Evaluation of a Replication-Deficient Recombinant Adenovirus Serotype 5 Vaccine Expressing Guanylate Cyclase C and the PADRE T-helper Epitope. 
  • Predictors of proteinuria and renal failure among women with HIV infection. 
  • Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys. 
  • Preexisting infection with human T-cell lymphotropic virus type 2 neither exacerbates nor attenuates simian immunodeficiency virus SIVmac251 infection in macaques. 
  • Preexisting memory CD4+ T cells contribute to the primary response in an HIV-1 vaccine trial. 
  • Preexisting vaccinia virus immunity decreases SIV-specific cellular immunity but does not diminish humoral immunity and efficacy of a DNA/MVA vaccine. 
  • Premature cell senescence and T cell receptor-independent activation of CD8+ T cells in juvenile idiopathic arthritis. 
  • Preservation of motor function by inhibition of CD8+ virus peptide-specific T cells in Theiler's virus infection. 
  • Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys. 
  • Prevention of disease induced by a partially heterologous AIDS virus in rhesus monkeys by using an adjuvanted multicomponent protein vaccine. 
  • Primary infection by a human immunodeficiency virus with atypical coreceptor tropism. 
  • Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges. 
  • Priming for virus-specific CD8+ but not CD4+ cytotoxic T lymphocytes with synthetic lipopeptide is influenced by acylation units and liposome encapsulation. 
  • Probiotic supplementation reduces inflammatory profiles but does not prevent oral immune perturbations during SIV infection. 
  • Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals differential expression of the immunologic transcriptome compared with T cells from healthy volunteers. 
  • Prolactin can modulate CD4+ T-cell response through receptor-mediated alterations in the expression of T-bet. 
  • Proliferation of HIV-infected renal epithelial cells following virus acquisition from infected macrophages. 
  • Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts. 
  • Protection of macaques against vaginal SHIV challenge by systemic or mucosal and systemic vaccinations with HIV-envelope. 
  • Protein Phosphatase 1α and Cofilin Regulate Nuclear Translocation of NF-κB and Promote Expression of the Anti-Inflammatory Cytokine Interleukin-10 by T Cells. 
  • Qa-1 restriction of CD8+ suppressor T cells. 
  • Quality control in the flow cytometric measurement of T-lymphocyte subsets: the multicenter AIDS cohort study experience. The Multicenter AIDS Cohort Study Group. 
  • Quantification of total T-cell receptor diversity by flow cytometry and spectratyping. 
  • Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production. 
  • Ranitidine improves lymphocyte function after severe head injury: results of a randomized, double-blind study. 
  • Rapid memory CD8+ T-lymphocyte induction through priming with recombinant Mycobacterium smegmatis. 
  • Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication. 
  • Receptor tyrosine kinase MerTK suppresses an allogenic type I IFN response to promote transplant tolerance. 
  • Recombinant BCG Expressing Mycobacterium ulcerans Ag85A Imparts Enhanced Protection against Experimental Buruli ulcer. 
  • Recombinant modified vaccinia virus Ankara provides durable protection against disease caused by an immunodeficiency virus as well as long-term immunity to an orthopoxvirus in a non-human primate. 
  • Recombinant rubella vectors elicit SIV Gag-specific T cell responses with cytotoxic potential in rhesus macaques. 
  • Recovery of interleukin-17 production from interleukin-15-stimulated CD4+ mononuclear cells in HIV-1-infected patients with sustained viral suppression. 
  • Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART® Molecules. 
  • Reduction of peak viremia by an integration-defective SIV proviral DNA vaccine in rhesus macaques. 
  • Reduction of simian-human immunodeficiency virus 89.6P viremia in rhesus monkeys by recombinant modified vaccinia virus Ankara vaccination. 
  • Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structure. 
  • Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. 
  • Regulation of ultraviolet radiation induced cutaneous photoimmunosuppression by toll-like receptor-4. 
  • Regulatory B cells as inhibitors of immune responses and inflammation. 
  • Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. 
  • Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation. 
  • Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease. 
  • Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques. 
  • Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC. 
  • Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity. 
  • Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells. 
  • Reprogramming after chromosome transfer into mouse blastomeres. 
  • Restriction in T-cell receptor repertoire in a patient affected by trichothiodystrophy and CD4+ lymphopenia. 
  • Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis. 
  • Retroviral E-DNA: persistence and gene expression in nondividing immune cells. 
  • Reversal of the T cell immune system reveals the molecular basis for T cell lineage fate determination in the thymus. 
  • RhCMV serostatus and vaccine adjuvant impact immunogenicity of RhCMV/SIV vaccines. 
  • Role of lymphoid organs in the pathogenesis of human immunodeficiency virus (HIV) infection. 
  • SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery. 
  • SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity. 
  • SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses. 
  • SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques. 
  • Safety and immune responses after a 12-month booster in healthy HIV-uninfected adults in HVTN 100 in South Africa: A randomized double-blind placebo-controlled trial of ALVAC-HIV (vCP2438) and bivalent subtype C gp120/MF59 vaccines. 
  • Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis. 
  • Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial. 
  • Selection of TCR V alpha by MHC class II predicts superantigen reactivity. 
  • Selective modification of antigen-specific T cells by RNA electroporation. 
  • Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses. 
  • Sequential Immunization with gp140 Boosts Immune Responses Primed by Modified Vaccinia Ankara or DNA in HIV-Uninfected South African Participants. 
  • Serum leptin and CD4+ T lymphocytes in HIV+ children during highly active antiretroviral therapy. 
  • Severe chronic graft-versus-host disease is characterized by a preponderance of CD4(+) effector memory cells relative to central memory cells. 
  • Sexually transmitted infections and immune activation among HIV-infected but virally suppressed youth on antiretroviral therapy. 
  • Short Communication: Small-Molecule CD4 Mimetics Sensitize HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity by Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Nonhuman Primates. 
  • Simian immunodeficiency virus DNA vaccine trial in macaques. 
  • Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4+ T Cells. 
  • Simulated microgravity-mediated reversion of murine lymphoma immune evasion. 
  • Simvastatin inhibits IFN regulatory factor 4 expression and Th17 cell differentiation in CD4+ T cells derived from patients with multiple sclerosis. 
  • Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. 
  • Single epitope mucosal vaccine delivered via immuno-stimulating complexes induces low level of immunity against simian-HIV. 
  • Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency. 
  • Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy. 
  • Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer. 
  • Somatic mosaicism caused by monoallelic reversion of a mutation in T cells of a patient with ADA-SCID and the effects of enzyme replacement therapy on the revertant phenotype. 
  • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. 
  • Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients. 
  • Stability of Th1 and Th2 populations. 
  • Stabilization of HIV-1 envelope in the CD4-bound conformation through specific cross-linking of a CD4 mimetic. 
  • Stable Latent HIV Infection and Low-level Viremia Despite Treatment With the Broadly Neutralizing Antibody VRC07-523LS and the Latency Reversal Agent Vorinostat. 
  • Statins' immunomodulatory potential against Th17 cell-mediated autoimmune response. 
  • Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses. 
  • Structural rearrangements in the transmembrane glycoprotein after receptor binding. 
  • Studies using a viral challenge and CD8 T cell depletions on the roles of cellular and humoral immunity in the control of an SHIV-89.6P challenge in DNA/MVA-vaccinated macaques. 
  • Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system. 
  • Substance P receptor mediated maintenance of chronic inflammation in EAE. 
  • Superfibronectin, a multimeric form of fibronectin, increases HIV infection of primary CD4+ T lymphocytes. 
  • Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses. 
  • Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer. 
  • Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease. 
  • Surrogate tolerogenesis: possible pretransplant induction of accommodation of pig xenografts. 
  • Survival of subretinal pancreatic islet cell allografts and apoptosis in infiltrating lymphocytes in rats. 
  • Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function. 
  • Systemic lupus erythematosus and HIV infection: a whimsical relationship. Reports of two cases and review of the literature. 
  • T Cell Responses against Mycobacterial Lipids and Proteins Are Poorly Correlated in South African Adolescents. 
  • T cell receptor gamma/delta expression on lymphocyte populations of breast cancer patients. 
  • T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10. 
  • T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers. 
  • T lymphocyte abnormalities in juvenile systemic sclerosis patients. 
  • T(H)2 bias: Mina tips the balance. 
  • T-bet:Eomes balance, effector function, and proliferation of cytomegalovirus-specific CD8+ T cells during primary infection differentiates the capacity for durable immune control. 
  • T-cell transcriptomics from peripheral blood highlights differences between polymyositis and dermatomyositis patients. 
  • TCR Repertoires of Thymic Conventional and Regulatory T Cells: Identification and Characterization of Both Unique and Shared TCR Sequences. 
  • TCR alpha-CD3 delta epsilon association is the initial step in alpha beta dimer formation in murine T cells and is limiting in immature CD4+ CD8+ thymocytes. 
  • TCR repertoire and CDR3 motif analyses depict the role of αβ T cells in Ankylosing spondylitis. 
  • TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation. 
  • Targeted and untargeted CD137L fusion proteins for the immunotherapy of experimental solid tumors. 
  • Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic. 
  • Targeting T-cell oxidative metabolism to improve influenza survival in a mouse model of obesity. 
  • Telomerase mRNA-transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer. 
  • Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients. 
  • Th1 inflammatory response with altered expression of profibrotic and vasoactive mediators in AT1A and AT1B double-knockout mice. 
  • The Clinical Spectrum of Primary Cutaneous CD4+ Small/Medium-Sized Pleomorphic T-Cell Lymphoproliferative Disorder: An Updated Systematic Literature Review and Case Series. 
  • The Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T Cells. 
  • The Immunology Quality Assessment Proficiency Testing Program for CD3⁺4⁺ and CD3⁺8⁺ lymphocyte subsets: a ten year review via longitudinal mixed effects modeling. 
  • The Importance of IL-6 in the Development of LAT-Mediated Autoimmunity. 
  • The MicroRNA miR-191 Supports T Cell Survival Following Common γ Chain Signaling. 
  • The diagnosis of severe combined immunodeficiency (SCID): The Primary Immune Deficiency Treatment Consortium (PIDTC) 2022 Definitions. 
  • The duration of zidovudine benefit in persons with asymptomatic HIV infection. Prolonged evaluation of protocol 019 of the AIDS Clinical Trials Group. 
  • The effector component of the cytotoxic T-lymphocyte response has a biphasic pattern after burn injury. 
  • The effects on survival of early treatment of human immunodeficiency virus infection. 
  • The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes. 
  • The global health and diagnostic (flow) cytometry--breakthroughs in HIV and tuberculosis. 
  • The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function. 
  • The human thymus. A chimeric organ comprised of central and peripheral lymphoid components. 
  • The importance of dominant negative effects of amino acid side chain substitution in peptide-MHC molecule interactions and T cell recognition. 
  • The interleukin-2 receptor α chain (CD25) plays an important role in regulating monocyte-derived CD40 expression during anti-porcine cellular responses. 
  • The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus. 
  • The presence of T-lymphocyte subpopulations (CD4 and CD8) in pterygia: evaluation of the inflammatory response. 
  • The prevalence of cervical regulatory T cells in HPV-related cervical intraepithelial neoplasia (CIN) correlates inversely with spontaneous regression of CIN. 
  • The requirement of reversible cysteine sulfenic acid formation for T cell activation and function. 
  • The role of fractalkine (CX3CL1) in regulation of CD4(+) cell migration to the central nervous system in patients with relapsing-remitting multiple sclerosis. 
  • The role of functionally distinct helper T lymphocyte subpopulations in the induction of human B cell differentiation. 
  • The role of innate APOBEC3G and adaptive AID immune responses in HLA-HIV/SIV immunized SHIV infected macaques. 
  • The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3',3'-dimethylsuccinyl}-betulinic acid. 
  • The trajectory patterns of single HIV-1 virus-like particle in live CD4 cells: A real time three-dimensional multi-resolution microscopy study using encapsulated nonblinking giant quantum dot. 
  • The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination. 
  • The variable loop 3 in the envelope glycoprotein is critical for the atypical coreceptor usage of an HIV-1 strain. 
  • Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice. 
  • Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1. 
  • Thymic model for examining BRCA2 expression and function. 
  • Thymic output markers indicate immune dysfunction in DiGeorge syndrome. 
  • Titrating T-cell epitopes within self-assembled vaccines optimizes CD4+ helper T cell and antibody outputs. 
  • Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells. 
  • Toward an understanding of the correlates of protective immunity to HIV infection. 
  • Transcriptional regulator Id2 is required for the CD4 T cell immune response in the development of experimental autoimmune encephalomyelitis. 
  • Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression. 
  • Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression. 
  • Transmembrane domain membrane proximal external region but not surface unit-directed broadly neutralizing HIV-1 antibodies can restrict dendritic cell-mediated HIV-1 trans-infection. 
  • Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7. 
  • Tumor immunotherapy targeting fibroblast activation protein, a product expressed in tumor-associated fibroblasts. 
  • Tumor-associated antigen-based personalized dendritic cell vaccine in solid tumor patients. 
  • Two-Year Follow-Up of Macaques Developing Intermittent Control of the Human Immunodeficiency Virus Homolog Simian Immunodeficiency Virus SIVmac251 in the Chronic Phase of Infection. 
  • Unexpected link between mitochondrial DNA and T cell help in systemic lupus erythematosus. 
  • Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells. 
  • Unique abnormalities of CD4(+) and CD8(+) central memory cells associated with chronic graft-versus-host disease improve after extracorporeal photopheresis. 
  • Unique cellular and humoral immunogenicity profiles generated by aerosol, intranasal, or parenteral vaccination in rhesus macaques. 
  • Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice. 
  • Upregulation of molecules associated with T-regulatory function by thymoglobulin pretreatment of human CD4+ cells. 
  • Using CD4 percentage and age to optimize pediatric antiretroviral therapy initiation. 
  • VERITAS?: A time for VERIQAS™ and a new approach to training, education, and the quality assessment of CD4+ T lymphocyte counting (I). 
  • Vaccination establishes clonal relatives of germinal center T cells in the blood of humans. 
  • Vaccination of macaques with long-standing SIVmac251 infection lowers the viral set point after cessation of antiretroviral therapy. 
  • Vaccination of vaccinia-naive adults with human immunodeficiency virus type 1 gp160 recombinant vaccinia virus in a blinded, controlled, randomized clinical trial. The AIDS Vaccine Clinical Trials Network. 
  • Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge. 
  • Vaccination with dendritic cells inhibits the growth of hepatic metastases in B6 mice. 
  • Vaccination with vif-deleted feline immunodeficiency virus provirus, GM-CSF, and TNF-alpha plasmids preserves global CD4 T lymphocyte function after challenge with FIV. 
  • Vaccine-induced boosting of influenza virus-specific CD4 T cells in younger and aged humans. 
  • Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells. 
  • Viral subversion of the immune system. 
  • Viremia control despite escape from a rapid and potent autologous neutralizing antibody response after therapy cessation in an HIV-1-infected individual. 
  • Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells. 
  • Zidovudine in asymptomatic human immunodeficiency virus infection. A controlled trial in persons with fewer than 500 CD4-positive cells per cubic millimeter. The AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases. 
  • beta-Endorphin-containing memory-cells and mu-opioid receptors undergo transport to peripheral inflamed tissue. 
  • mTOR is critical for intestinal T-cell homeostasis and resistance to Citrobacter rodentium. 
  • mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation. 
  • microRNAs at the regulatory frontier: an investigation into how microRNAs impact the development and effector functions of CD4 T cells. 
  • polyethylene glycol-conjugated adenosine deaminase (ADA) therapy provides temporary immune reconstitution to a child with delayed-onset ADA deficiency. 
  • rHuKGF ameliorates symptoms in DSS and CD4(+)CD45RB(Hi) T cell transfer mouse models of inflammatory bowel disease. 
  • β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway. 
  • β-Arrestin-2-Dependent Signaling Promotes CCR4-mediated Chemotaxis of Murine T-Helper Type 2 Cells. 
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  Keywords of People

  • Chen, Jun, Professor of Medicine, Duke Cancer Institute
  • Ciofani, Maria, Associate Professor of Integrative Immunobiology, Cell Biology
  • Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology
  • Gunn, Michael Dee, Professor of Medicine, Integrative Immunobiology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Integrative Immunobiology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
  • Shinohara, Mari L., Professor of Integrative Immunobiology, Cell Biology
  • Sparks, Matthew A., Associate Professor of Medicine, Medicine, Nephrology
  • Taylor, Gregory Alan, Professor in Medicine, Integrative Immunobiology
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Integrative Immunobiology
  • Zhong, Xiaoping, Professor of Pediatrics, Integrative Immunobiology