-
Subject Areas on Research
-
14-3-3 proteins are part of an abscisic acid-VIVIPAROUS1 (VP1) response complex in the Em promoter and interact with VP1 and EmBP1.
-
3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency.
-
4D MRI of polycystic kidneys from rapamycin-treated Glis3-deficient mice.
-
A Common Glaucoma-risk Variant of SIX6 Alters Retinal Nerve Fiber Layer and Optic Disc Measures in a European Population: The EPIC-Norfolk Eye Study.
-
A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist.
-
A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy.
-
A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation.
-
A TAZ-ANGPTL4-NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer.
-
A VGF-derived peptide attenuates development of type 2 diabetes via enhancement of islet β-cell survival and function.
-
A c-Fos- and E1A-interacting component of the tissue factor basal promoter complex mediates synergistic activation of transcription by transforming growth factor-beta1.
-
A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4).
-
A conserved domain of the viviparous-1 gene product enhances the DNA binding activity of the bZIP protein EmBP-1 and other transcription factors.
-
A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumor.
-
A human erythropoietin receptor gene mutant causing familial erythrocytosis is associated with deregulation of the rates of Jak2 and Stat5 inactivation.
-
A micromere induction signal is activated by beta-catenin and acts through notch to initiate specification of secondary mesenchyme cells in the sea urchin embryo.
-
A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis.
-
A mutant PTH/PTHrP type I receptor in enchondromatosis.
-
A new activating role for CO in cardiac mitochondrial biogenesis.
-
A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas.
-
A role for sonic hedgehog signaling in the pathogenesis of human tracheoesophageal fistula.
-
A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation.
-
A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression.
-
A structure-based mechanism for drug binding by multidrug transporters.
-
A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with Staphylococcal aureus sepsis.
-
A yeast TATA-binding protein mutant that selectively enhances gene expression from weak RNA polymerase II promoters.
-
ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling.
-
AP-1 and STAT mediate hyperoxia-induced gene transcription of heme oxygenase-1.
-
APC-mediated downregulation of beta-catenin activity involves nuclear sequestration and nuclear export.
-
Abnormal mouse lung alveolarization caused by Smad3 deficiency is a developmental antecedent of centrilobular emphysema.
-
Activated armadillo/beta-catenin does not play a general role in cell migration and process extension in Drosophila.
-
Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility.
-
Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine.
-
Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.
-
Activation of orphan receptor-mediated transcription by Ca(2+)/calmodulin-dependent protein kinase IV.
-
Activation of pmar1 controls specification of micromeres in the sea urchin embryo.
-
Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2.
-
Adaptive mechanisms that preserve cardiac function in mice without myoglobin.
-
Adaptor proteins in lymphocyte activation.
-
Adenomatous polyposis coli gene mutation alters proliferation through its beta-catenin-regulatory function in aggressive fibromatosis (desmoid tumor).
-
Age-related changes in the cellular composition and epithelial organization of the mouse trachea.
-
Airway-specific inducible transgene expression using aerosolized doxycycline.
-
An essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*.
-
An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses.
-
Analysis of the role of E2A-encoded proteins in insulin gene transcription.
-
Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation.
-
Apolipoprotein E isotype-dependent modulation of microRNA-146a in plasma and brain.
-
Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF.
-
Association between the N-terminally truncated (DeltaN) p63alpha (DeltaNp63alpha) isoform and debulking status, VEGF expression and progression-free survival in previously untreated, advanced stage epithelial ovarian cancer: A Gynecologic Oncology Group study.
-
Association of common SIX6 polymorphisms with peripapillary retinal nerve fiber layer thickness: the Singapore Chinese Eye Study.
-
B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.
-
BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.
-
BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia.
-
BMPs induce dermal markers and ectopic feather tracts.
-
Beryllofluoride mimics phosphorylation of NtrC and other bacterial response regulators.
-
Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway.
-
Beta-catenin expression in Dupuytren's disease: potential role for cell-matrix interactions in modulating beta-catenin levels in vivo and in vitro.
-
Biological activity of interleukin-10 in the central nervous system.
-
Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development.
-
Branching morphogenesis of the lung: new models for a classical problem.
-
CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC.
-
CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine retrovirus SL3-3 in T lymphocytes.
-
Calcineurin is required for Candida albicans to survive calcium stress in serum.
-
Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus.
-
Calcineurin-NFAT signaling, together with GABP and peroxisome PGC-1{alpha}, drives utrophin gene expression at the neuromuscular junction.
-
Calcium dependent CAMTA1 in adult stem cell commitment to a myocardial lineage.
-
Calponin-3 deficiency augments contractile activity, plasticity, fibrogenic response and Yap/Taz transcriptional activation in lens epithelial cells and explants.
-
Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury.
-
Cardiac repolarization: current knowledge, critical gaps, and new approaches to drug development and patient management.
-
Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex.
-
Casein kinase Iepsilon plays a functional role in the transforming growth factor-beta signaling pathway.
-
Cell cycle: Flies teach an old dogma new tricks.
-
Cell lineage mapping of taste bud cells and keratinocytes in the mouse tongue and soft palate.
-
Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors.
-
Changes in the pattern of adherens junction-associated beta-catenin accompany morphogenesis in the sea urchin embryo.
-
Chaperone-mediated 26S proteasome remodeling facilitates free K63 ubiquitin chain production and aggresome clearance.
-
Characterization of the SarA virulence gene regulator of Staphylococcus aureus.
-
Characterization of the role of cadherin in regulating cell adhesion during sea urchin development.
-
Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein.
-
Characterization of the transcriptional trans activator of human foamy retrovirus.
-
Characterization of transcriptional activation and DNA-binding functions in the hinge region of the vitamin D receptor.
-
Checkpoint signals in grasshopper meiosis are sensitive to microtubule attachment, but tension is still essential.
-
Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis.
-
Chromatin accessibility mapping identifies mediators of basal transcription and retinoid-induced repression of OTX2 in medulloblastoma.
-
Cigarette smoke modulates vascular smooth muscle phenotype: implications for carotid and cerebrovascular disease.
-
Circular RNA RSF1 promotes inflammatory and fibrotic phenotypes of irradiated hepatic stellate cell by modulating miR-146a-5p.
-
Clamp subunit dissociation dictates bacteriophage T4 DNA polymerase holoenzyme disassembly.
-
Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.
-
Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma.
-
Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene.
-
Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements.
-
Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus.
-
Computing a Synthetic Chronic Psychosocial Stress Measurement in Multiple Datasets and its Application in the Replication of G × E Interactions of the EBF1 Gene.
-
Conformational plasticity of the coiled-coil domain of BmrR is required for bmr operator binding: the structure of unliganded BmrR.
-
Conformational studies of the nucleic acid binding sites for Xenopus transcription factor IIIA.
-
Connections and regulation of the human estrogen receptor.
-
Consensus and variant cAMP-regulated enhancers have distinct CREB-binding properties.
-
Conserved functional organization of the human immunodeficiency virus type 1 and visna virus Rev proteins.
-
Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation.
-
Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation.
-
Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing.
-
Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promoting MHC class II expression via IRF4 and CIITA.
-
Crystal structure of MtaN, a global multidrug transporter gene activator.
-
Crystal structure of the transcription activator BmrR bound to DNA and a drug.
-
Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus.
-
Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae.
-
Cyclooxygenase-two (COX-2) modulates proliferation in aggressive fibromatosis (desmoid tumor).
-
Cytokine signals through STAT3 promote expression of granulocyte secondary granule proteins in 32D cells.
-
Cytokine transcriptional events during helper T cell subset differentiation.
-
Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma.
-
Definition of a FoxA1 Cistrome that is crucial for G1 to S-phase cell-cycle transit in castration-resistant prostate cancer.
-
Dependence of corneal stem/progenitor cells on ocular surface innervation.
-
Derivation and functional characterization of a consensus DNA binding sequence for the tas transcriptional activator of simian foamy virus type 1.
-
Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis.
-
Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors.
-
Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors.
-
Development of peptide antagonists that target estrogen receptor beta-coactivator interactions.
-
Developmental biology informs cancer: the emerging role of the hedgehog signaling pathway in upper gastrointestinal cancers.
-
Developmental pathways in musculoskeletal neoplasia: involvement of the Indian Hedgehog-parathyroid hormone-related protein pathway.
-
Differential expression of p63 isoforms in female reproductive organs.
-
Differential regulation of the PGC family of genes in a mouse model of Staphylococcus aureus sepsis.
-
Differential requirement for STAT by gain-of-function and wild-type receptor tyrosine kinase Torso in Drosophila.
-
Dimerization of a chimeric CD4-interferon-alpha receptor reconstitutes the signaling events preceding STAT phosphorylation.
-
Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase.
-
Discovery and functional annotation of SIX6 variants in primary open-angle glaucoma.
-
Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss.
-
Dissecting the order of bacteriophage T4 DNA polymerase holoenzyme assembly.
-
Distinct regions of the cadherin cytoplasmic domain are essential for functional interaction with Galpha 12 and beta-catenin.
-
Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation.
-
Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic β cell fate in response to cytokines.
-
Does the human immunodeficiency virus Tat trans-activator contain a discrete activation domain?
-
Down-regulation of neu/HER-2 by interferon-gamma in prostate cancer cells.
-
Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin
-
Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis.
-
Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells.
-
Drosophila Tcf and Groucho interact to repress Wingless signalling activity.
-
Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component.
-
Dysregulation of hedgehog signalling predisposes to synovial chondromatosis.
-
EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development.
-
Early differential elevation and persistence of phosphorylated cAMP-response element binding protein (p-CREB) in the central nervous system of hens treated with diisopropyl phosphorofluoridate, an OPIDN-causing compound.
-
Elevated levels of beta-catenin and fibronectin in three-dimensional collagen cultures of Dupuytren's disease cells are regulated by tension in vitro.
-
Engineering key components in a synthetic eukaryotic signal transduction pathway.
-
Enhancer-origin interaction in plasmid R6K involves a DNA loop mediated by initiator protein.
-
Epigenetic control of intestinal barrier function and inflammation in zebrafish.
-
Epstein-Barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency.
-
Erythropoietin activates mitochondrial biogenesis and couples red cell mass to mitochondrial mass in the heart.
-
Erythropoietin hypersensitivity in primary familial and congenital polycythemia: role of tyrosines Y285 and Y344 in erythropoietin receptor cytoplasmic domain.
-
Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation.
-
Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors.
-
Evaluating the precision of EBF1 SNP x stress interaction association: sex, race, and age differences in a big harmonized data set of 28,026 participants.
-
Evidence for the involvement of the Gli gene family in embryonic mouse lung development.
-
Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis.
-
Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.
-
Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway.
-
Expression and hormonal regulation of coactivator and corepressor genes.
-
Expression of a murine cytomegalovirus early-late protein in "latently" infected mice.
-
Expression of bone morphogenetic protein-4 (BMP-4), bone morphogenetic protein-7 (BMP-7), fibroblast growth factor-8 (FGF-8) and sonic hedgehog (SHH) during branchial arch development in the chick.
-
Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog.
-
Expression of the vaccinia virus A2.5L redox protein is required for virion morphogenesis.
-
Expression, purification and primary crystallographic study of human androgen receptor in complex with DNA and coactivator motifs.
-
FBW2 targets GCMa to the ubiquitin-proteasome degradation system.
-
Familial polycythemia due to truncations of the erythropoietin receptor.
-
Female steroid hormones use signal transducers and activators of transcription protein-mediated pathways to modulate the expression of T-bet in epithelial cells: a mechanism for local immune regulation in the human reproductive tract.
-
Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung.
-
FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.
-
Frequent TMPRSS2-ERG rearrangement in prostatic small cell carcinoma detected by fluorescence in situ hybridization: the superiority of fluorescence in situ hybridization over ERG immunohistochemistry.
-
Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome.
-
Functional Variants in Notch Pathway Genes NCOR2, NCSTN, and MAML2 Predict Survival of Patients with Cutaneous Melanoma.
-
Functional analysis of the Tat trans activator of human immunodeficiency virus type 2.
-
Functional comparison of the Rev trans-activators encoded by different primate immunodeficiency virus species.
-
Functional organization of the Bel-1 trans activator of human foamy virus.
-
Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein.
-
Functional similarities between HIV-1 Tat and DNA sequence-specific transcriptional activators.
-
G(s)alpha deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency.
-
Gadolinium chloride alters the acinar distribution of phagocytosis and balance between pro- and anti-inflammatory cytokines.
-
Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene.
-
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.
-
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP.
-
Genetic analysis indicates that the human foamy virus Bel-1 protein contains a transcription activation domain of the acidic class.
-
Genetic variants in the PIWI-piRNA pathway gene DCP1A predict melanoma disease-specific survival.
-
Genome-wide analysis of STAT target genes: elucidating the mechanism of STAT-mediated oncogenesis.
-
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.
-
Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis.
-
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer.
-
Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape.
-
Genotypic characteristics of Staphylococcus aureus isolates from a multinational trial of complicated skin and skin structure infections.
-
Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis.
-
Global analysis of the relationship between the binding of the Bas1p transcription factor and meiosis-specific double-strand DNA breaks in Saccharomyces cerevisiae.
-
Global re-wiring of p53 transcription regulation by the hepatitis B virus X protein.
-
Growth factors regulate beta-catenin-mediated TCF-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing.
-
HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence.
-
HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey.
-
Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein.
-
Hedgehog signaling maintains resident hepatic progenitors throughout life.
-
Hepatocyte nuclear factor-4alpha mediates redox sensitivity of inducible nitric-oxide synthase gene transcription.
-
High-resolution solution structure of the beryllofluoride-activated NtrC receiver domain.
-
Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3.
-
Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo.
-
Human T-cell leukemia virus type 1 tax attenuates the ATM-mediated cellular DNA damage response.
-
Human immunodeficiency virus type 1 (HIV-1) induces activation of multiple STATs in CD4+ cells of lymphocyte or monocyte/macrophage lineages.
-
Human immunodeficiency virus type 1 rev protein as a negative trans-regulator.
-
Hydrophobic residues Phe751 and Leu753 are essential for STAT5 transcriptional activity.
-
Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP.
-
Hypoxia-inducible factor pathway genes predict survival in metastatic clear cell renal cell carcinoma.
-
Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter.
-
IL-13 and IL-1beta promote lung fibroblast growth through coordinated up-regulation of PDGF-AA and PDGF-Ralpha.
-
ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation.
-
Identification and functional characterization of a high-affinity Bel-1 DNA binding site located in the human foamy virus internal promoter.
-
Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors.
-
Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid.
-
Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing.
-
Identification of a cell of origin for human prostate cancer.
-
Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors.
-
Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle.
-
Identification of hepatitis B virus aetiologic antigens, HBx and Pre-S2, in diffuse large B-cell lymphoma.
-
Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.
-
Identification of novel steroid-response elements.
-
Identification of the TBX5 transactivating domain and the nuclear localization signal.
-
Ihh controls cartilage development by antagonizing Gli3, but requires additional effectors to regulate osteoblast and vascular development.
-
Immunohistochemical and genetic analysis of non-small cell and small cell gallbladder carcinoma and their precursor lesions.
-
Immunomodulation of experimental autoimmune encephalomyelitis by helminth ova immunization.
-
Importance of a c-Myb binding site for lymphomagenesis by the retrovirus SL3-3.
-
In vitro interleukin-6 treatment prevents mortality associated with fatty liver transplants in rats.
-
In-vivo studies on the cis-acting replication initiator protein of IncFII plasmid NR1.
-
Increase in PDX-1 levels suppresses insulin gene expression in RIN 1046-38 cells.
-
Increased beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatoses (desmoid tumors).
-
Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus.
-
Inducible regulation of Runx2-stimulated osteogenesis.
-
Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
-
Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro.
-
Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.
-
Innate inhibition of adaptive immunity: Mycobacterium tuberculosis-induced IL-6 inhibits macrophage responses to IFN-gamma.
-
Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation.
-
Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release.
-
Interferon gamma (IFNgamma) gene transfer of an EMT6 tumor that is poorly responsive to IFNgamma stimulation: increase in tumor immunogenicity is accompanied by induction of a mouse class II transactivator and class II MHC.
-
Interleukin-3-induced activation of the JAK/STAT pathway is prolonged by proteasome inhibitors.
-
Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry.
-
Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis.
-
Involvement of the mt1 melatonin receptor in human breast cancer.
-
Isolation and characterization of the replicon of a Thiobacillus intermedius plasmid.
-
Isolation and initial characterization of the BRCA2 promoter.
-
Isolation of two E-box binding factors that interact with the rat tyrosine hydroxylase enhancer.
-
Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification.
-
Isoprenylcysteine carboxylmethyltransferase is required for the impact of mutant KRAS on TAZ protein level and cancer cell self-renewal.
-
JAK2 is required for induction of the murine DUB-1 gene.
-
Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation.
-
Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence.
-
LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression.
-
Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor.
-
Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3.
-
Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast.
-
Lineage-specific signaling in melanocytes. C-kit stimulation recruits p300/CBP to microphthalmia.
-
Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1.
-
Lovastatin-induced cytoskeletal reorganization in lens epithelial cells: role of Rho GTPases.
-
LvGroucho and nuclear beta-catenin functionally compete for Tcf binding to influence activation of the endomesoderm gene regulatory network in the sea urchin embryo.
-
LvNotch signaling plays a dual role in regulating the position of the ectoderm-endoderm boundary in the sea urchin embryo.
-
LvTbx2/3, a T-box Family Transcription Factor Involved in Formation of the Oral/Aboral Axis of the Sea Urchin Embryo
-
Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells.
-
MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300.
-
Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth.
-
Maternal Diet and Insulin-Like Signaling Control Intergenerational Plasticity of Progeny Size and Starvation Resistance.
-
Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes.
-
Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
-
Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors.
-
Mitochondrial biogenesis restores oxidative metabolism during Staphylococcus aureus sepsis.
-
Modeling Glaucoma: Retinal Ganglion Cells Generated from Induced Pluripotent Stem Cells of Patients with SIX6 Risk Allele Show Developmental Abnormalities.
-
Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1.
-
Mouse Mesenchyme forkhead 2 (Mf2): expression, DNA binding and induction by sonic hedgehog during somitogenesis.
-
Multiparity leads to obesity and inflammation in mothers and obesity in male offspring.
-
Multiple different missense mutations in the pore region of HERG in patients with long QT syndrome.
-
Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm.
-
Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector.
-
Muscle oxidative capacity during IL-6-dependent cancer cachexia.
-
Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.
-
Mutation of p53 gene in hepatocellular carcinoma cell lines with HBX DNA.
-
Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat.
-
Myocardin induces cardiomyocyte hypertrophy.
-
N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma.
-
Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways.
-
Negative feedback control of jasmonate signaling by an alternative splice variant of JAZ10.
-
Negative regulation of Armadillo, a Wingless effector in Drosophila.
-
Neuronal CRTC-1 governs systemic mitochondrial metabolism and lifespan via a catecholamine signal.
-
Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice.
-
Nomenclature: vertebrate mediators of TGFbeta family signals.
-
Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.
-
Novel gene functions required for melanization of the human pathogen Cryptococcus neoformans.
-
Novel missense mutation in the cyclic nucleotide-binding domain of HERG causes long QT syndrome.
-
Nuclear beta-catenin is required to specify vegetal cell fates in the sea urchin embryo.
-
Nuclear beta-catenin-dependent Wnt8 signaling in vegetal cells of the early sea urchin embryo regulates gastrulation and differentiation of endoderm and mesodermal cell lineages.
-
Nuclear protein CBP is a coactivator for the transcription factor CREB.
-
Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion.
-
Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study.
-
Oxidative phenotype protects myofibers from pathological insults induced by chronic heart failure in mice.
-
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum.
-
PGC-1alpha mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle.
-
PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans.
-
Paracrine signaling through the JAK/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila.
-
Paralogous VDRs in teleosts:transition of nuclear receptor function
-
Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.
-
Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1).
-
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals.
-
Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein.
-
Persistent expression of MNF identifies myogenic stem cells in postnatal muscles.
-
Peutz-Jeghers LKB1 mutants fail to activate GSK-3beta, preventing it from inhibiting Wnt signaling.
-
Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein.
-
Plasmacellular differentiation in extranodal marginal zone B cell lymphomas of the ocular adnexa: an analysis of the neoplastic plasma cell phenotype and its prognostic significance in 136 cases.
-
Polyploidization and cell fusion contribute to wound healing in the adult Drosophila epithelium.
-
Post-transcriptional regulation of MTA family by microRNAs in the context of cancer.
-
Precise pattern of recombination in serotonergic and hypothalamic neurons in a Pdx1-cre transgenic mouse line.
-
Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor).
-
Preliminary structural studies on the multi-ligand-binding domain of the transcription activator, BmrR, from Bacillus subtilis.
-
Prokaryotic transcription regulators: more than just the helix-turn-helix motif.
-
Prolactin induction of insulin gene transcription: roles of glucose and signal transducer and activator of transcription 5.
-
Prolonged beta-catenin stabilization and tcf-dependent transcriptional activation in hyperplastic cutaneous wounds.
-
Prolonged survival of class II transactivator-deficient cardiac allografts.
-
Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains.
-
Promotion of the development of enteric neurons and glia by neuropoietic cytokines: interactions with neurotrophin-3.
-
Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription.
-
Protein interactions among the vaccinia virus late transcription factors.
-
Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation.
-
Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus.
-
Protein phosphatase 2A: a panoply of enzymes.
-
Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II.
-
Protein-protein and protein-DNA interactions at the bacteriophage T4 DNA replication fork. Characterization of a fluorescently labeled DNA polymerase sliding clamp.
-
Proteomic analysis of calcium/calmodulin-dependent protein kinase I and IV in vitro substrates reveals distinct catalytic preferences.
-
Quantitative Trait Locus Analysis of SIX1-SIX6 With Retinal Nerve Fiber Layer Thickness in Individuals of European Descent.
-
Quantitative, noninvasive imaging of radiation-induced DNA double-strand breaks in vivo.
-
Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa.
-
RAP2 mediates mechanoresponses of the Hippo pathway.
-
ROR alpha augments thyroid hormone receptor-mediated transcriptional activation.
-
RacGap50C negatively regulates wingless pathway activity during Drosophila embryonic development.
-
Rapid selection of tetracycline-controlled inducible cell lines using a green fluorescent-transactivator fusion protein.
-
Reactivation of Epstein-Barr Virus by HIF-1α Requires p53.
-
Receptors that induce erythroid differentiation of Ba/F3 cells: structural requirements and effect on STAT5 binding.
-
Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family.
-
Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.
-
Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation.
-
Redox-mediated upregulation of hepatocyte iNOS transcription requires coactivator PC4.
-
Reduced susceptibility of Staphylococcus aureus to vancomycin and platelet microbicidal protein correlates with defective autolysis and loss of accessory gene regulator (agr) function.
-
Regulation of E2A activities by histone acetyltransferases in B lymphocyte development.
-
Regulation of T-cell survival and mitochondrial homeostasis by TSC1.
-
Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A.
-
Regulation of early adipose commitment by Zfp521.
-
Regulation of mast cell survival and function by tuberous sclerosis complex 1.
-
Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL.
-
Regulation of the transcriptional activator NtrC1: structural studies of the regulatory and AAA+ ATPase domains.
-
Regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF-A) expression in podocytes.
-
Requirement for JAK/STAT signaling throughout border cell migration in Drosophila.
-
Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.
-
Retrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneurons.
-
Ribosome exchange revisited: a mechanism for translation-coupled ribosome detachment from the ER membrane.
-
Ribozyme cleavage of a 2,5-phosphodiester linkage: mechanism and a restricted divalent metal-ion requirement.
-
Role for hedgehog signaling in hepatic stellate cell activation and viability.
-
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.
-
Role of transforming growth factor Beta in human cancer.
-
SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility.
-
SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators.
-
SOCS36E, a novel Drosophila SOCS protein, suppresses JAK/STAT and EGF-R signalling in the imaginal wing disc.
-
SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression.
-
STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers.
-
STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection.
-
STAT6-independent production of IL-4 by mast cells.
-
Selective LXXLL peptides antagonize transcriptional activation by the retinoid-related orphan receptor RORgamma.
-
Senescent phenotypes and telomere lengths of peripheral blood T-cells mobilized by acute exercise in humans.
-
Sequential roles of Hedgehog and Wnt signaling in osteoblast development.
-
Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface.
-
Signaling by wingless in Drosophila.
-
Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury.
-
Sliding clamp of the bacteriophage T4 polymerase has open and closed subunit interfaces in solution.
-
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice.
-
Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells.
-
Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction.
-
Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta.
-
Smad5 induces ventral fates in Xenopus embryo.
-
Smads "freeze" when they ski.
-
Smads bind directly to the Jun family of AP-1 transcription factors.
-
Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2.
-
Sonic hedgehog is required for cardiac outflow tract and neural crest cell development.
-
Sox2 is required for development of taste bud sensory cells.
-
Specific binding of the human T-cell leukemia virus type I Rex protein to a short RNA sequence located within the Rex-response element.
-
Specification of endoderm and mesoderm in the sea urchin.
-
Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina.
-
Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process.
-
Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling.
-
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.
-
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis.
-
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.
-
Stimulation of different subtypes of angiotensin II receptors, AT1 and AT2 receptors, regulates STAT activation by negative crosstalk.
-
Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
-
Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter.
-
Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
-
Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action.
-
Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion.
-
Study of a US cohort supports the role of ZNF644 and high-grade myopia susceptibility.
-
Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis.
-
Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
-
Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice.
-
Suppressor of fused negatively regulates beta-catenin signaling.
-
TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein.
-
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.
-
Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells.
-
Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction.
-
Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs.
-
Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour).
-
The 2015 World Health Organization Classification of Tumors of the Pleura: Advances since the 2004 Classification.
-
The Bel-1 protein of human foamy virus activates human immunodeficiency virus type 1 gene expression via a novel DNA target site.
-
The Epstein-Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression.
-
The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma.
-
The MotA transcriptional activator of bacteriophage T4 binds to its specific DNA site as a monomer.
-
The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.
-
The Role of Brachyruy (T) During Gastrulations Movement in the Sea Urchin, Lytechinus variegatus
-
The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals.
-
The Salmonella Secreted Effector SarA/SteE Mimics Cytokine Receptor Signaling to Activate STAT3.
-
The Smads: transcriptional regulation and mouse models.
-
The Transcriptional Coactivator TAZ Is a Potent Mediator of Alveolar Rhabdomyosarcoma Tumorigenesis.
-
The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence.
-
The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation.
-
The crystal structure of the Escherichia coli MobA protein provides insight into molybdopterin guanine dinucleotide biosynthesis.
-
The dishevelled protein is modified by wingless signaling in Drosophila.
-
The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments.
-
The gamma2 late glycoprotein K promoter of equine herpesvirus 1 is differentially regulated by the IE and EICP0 proteins.
-
The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome.
-
The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo.
-
The human foamy virus Bel-1 transcription factor is a sequence-specific DNA binding protein.
-
The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis.
-
The mammalian twisted gastrulation gene functions in foregut and craniofacial development.
-
The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.
-
The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis.
-
The promoter of human T-cell leukemia virus type-I is repressed by the immediate-early gene region of human cytomegalovirus in primary blood lymphocytes.
-
The role of Alzheimer's disease-related presenilin 1 in intercellular adhesion.
-
The role of Smad3 in mediating mouse hepatic stellate cell activation.
-
The roles of orphan nuclear receptors in the development and function of the immune system.
-
The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus.
-
The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair.
-
The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
-
The transcription factor B-Myb is maintained in an inhibited state in target cells through its interaction with the nuclear corepressors N-CoR and SMRT.
-
The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle.
-
The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2.
-
Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation.
-
Tissue interactions pattern the mesenchyme of the embryonic mouse lung.
-
Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway.
-
Trans-activating rev protein of the human immunodeficiency virus 1 interacts directly and specifically with its target RNA.
-
Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway.
-
Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming.
-
Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae.
-
Transcription-associated mutation of lasR in Pseudomonas aeruginosa.
-
Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors.
-
Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells.
-
Transcriptional trans activators of human and simian foamy viruses contain a small, highly conserved activation domain.
-
Transdifferentiation of human endothelial progenitors into smooth muscle cells.
-
Transforming growth factor beta 1 dysregulation in a human oral carcinoma tumour progression model.
-
Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element.
-
Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines.
-
Transforming growth factor-beta1 inhibition of vascular smooth muscle cell activation is mediated via Smad3.
-
Transgenic mice expressing a constitutively active retinoic acid receptor in the lens exhibit ocular defects.
-
Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice.
-
Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism.
-
Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein.
-
Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle.
-
Twist is an integrator of SHH, FGF, and BMP signaling.
-
Two novel TP63 mutations associated with the ankyloblepharon, ectodermal defects, and cleft lip and palate syndrome: a skin fragility phenotype.
-
Ubiquitin-mediated degradation a mechanism for fine-tuning TGF-beta signaling.
-
Uncoupling of the signaling and caspase-inhibitory properties of X-linked inhibitor of apoptosis.
-
Vanadium-induced STAT-1 activation in lung myofibroblasts requires H2O2 and P38 MAP kinase.
-
Variants in Notch signalling pathway genes, PSEN1 and MAML2, predict overall survival in Chinese patients with epithelial ovarian cancer.
-
Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection.
-
Wnt signalling shows its versatility.
-
YAP/TAZ Mediate TGFβ2-Induced Schlemm's Canal Cell Dysfunction.
-
[A study of E-cadherin and beta-catenin expression and their correlation with prognosis of nonsmall cell lung carcinoma].
-
alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells.
-
beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds.
-
dishevelled and armadillo act in the wingless signalling pathway in Drosophila.
-
gli-1 Oncogene is highly expressed in granulomatous skin disorders, including sarcoidosis, granuloma annulare, and necrobiosis lipoidica diabeticorum.
-
hMad4, c-Myc endogenous inhibitor, induces a replicative senescence-like state when overexpressed in human fibroblasts.
-
p16 Inactivation in pancreatic intraepithelial neoplasias (PanINs) arising in patients with chronic pancreatitis.
-
p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.
-
p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.
-
p38gamma mitogen-activated protein kinase is a key regulator in skeletal muscle metabolic adaptation in mice.
-
p38γ activity is required for maintenance of slow skeletal muscle size.
-
p63 expression profile in normal and malignant prostate epithelial cells.
-
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.
-
β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium.
-
Keywords of People
-
-
Bejsovec, Amy,
Associate Professor of Biology,
Biology
-
Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
-
Buckley, Rebecca Hatcher,
Professor Emeritus of Pediatrics,
Pediatrics, Allergy and Immunology
-
Erickson, Harold Paul,
Professor Emeritus of Cell Biology,
Cell Biology
-
Hartemink, Alexander J.,
Professor in the Department of Computer Science,
Biology
-
Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
-
Liu, Yutao,
Adjunct Assistant Professor in the Department of Medicine,
Medicine, Medical Genetics
-
McDonnell, Donald Patrick,
Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine,
Cell Biology
-
McLendon, Roger Edwin,
Professor of Pathology,
Pathology
-
Pitt, Geoffrey Stuart,
Adjunct Professor in the Department of Medicine,
Medicine, Cardiology
-
Yan, Hai,
Adjunct Professor of Pathology,
Pathology
-
Zhong, Xiaoping,
Professor of Pediatrics,
Immunology