Mammary Neoplasms, Animal

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  Subject Areas on Research

  • A Quantitative Diffuse Reflectance Imaging (QDRI) System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins. 
  • A novel rodent mammary window of orthotopic breast cancer for intravital microscopy. 
  • ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming. 
  • Adipocyte mesenchymal transition contributes to mammary tumor progression. 
  • Anti-angiogenic effects of interleukin-12 delivered by a novel hyperthermia induced gene construct. 
  • Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis. 
  • CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer. 
  • Differences in leucocyte-endothelium interactions between normal and adenocarcinoma bearing tissues in response to radiation. 
  • Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior. 
  • Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice. 
  • Endocrine modulation of reproduction. 
  • Enhancing Radiation Therapy Through Cherenkov Light-Activated Phototherapy. 
  • Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression. 
  • Evidence for an alternative glycolytic pathway in rapidly proliferating cells. 
  • Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle in rats. 
  • G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program. 
  • Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis. 
  • Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells. 
  • Ligand-specific dynamics of the androgen receptor at its response element in living cells. 
  • Mammary gland morphology in Sprague-Dawley rats following treatment with an organochlorine mixture in utero and neonatal genistein. 
  • Metabolic plasticity of metastatic breast cancer cells: adaptation to changes in the microenvironment. 
  • Metaboloptics: Visualization of the tumor functional landscape via metabolic and vascular imaging. 
  • Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent. 
  • Near-simultaneous intravital microscopy of glucose uptake and mitochondrial membrane potential, key endpoints that reflect major metabolic axes in cancer. 
  • Number of pregnancies and ovariectomy modify mammary carcinoma development in transgenic HER-2/neu female mice. 
  • Oncogene pathway activation in mammary tumors dictates FDG-PET uptake. 
  • Perivascular oxygen tensions in a transplantable mammary tumor growing in a dorsal flap window chamber. 
  • Persistent genetic instability in cancer cells induced by non-DNA-damaging stress exposures. 
  • RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence. 
  • Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. 
  • STING suppresses bone cancer pain via immune and neuronal modulation. 
  • Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo. 
  • The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma. 
  • The pervasive presence of fluctuating oxygenation in tumors. 
  • The type III TGF-beta receptor suppresses breast cancer progression through GIPC-mediated inhibition of TGF-beta signaling. 
  • The type III TGF-beta receptor suppresses breast cancer progression. 
  • Tumor vascular permeability to a nanoprobe correlates to tumor-specific expression levels of angiogenic markers. 
  • Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. 
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  Keywords of People

  • Badea, Cristian Tudorel, Professor in Radiology, Biomedical Engineering