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Subject Areas on Research
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A radiologic syndrome after high dose chemotherapy and autologous bone marrow transplantation, with clinical and pathologic features of systemic candidiasis.
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A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole.
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AIDSāassociated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic dilemma in resourceālimited settings.
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AMBITION-cm: intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa: study protocol for a randomized controlled trial.
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Alopecia associated with fluconazole therapy.
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An observational study on the epidemiological and mycological profile of Candidemia in ICU patients.
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Antifungal Extraction by the Extracorporeal Membrane Oxygenation Circuit.
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Antifungal Susceptibility and Clinical Outcome in Neonatal Candidiasis.
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Antifungal resistance: the clinical front.
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Antifungal therapy and outcomes in infants with invasive Candida infections.
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Approaches to antifungal therapies and their effectiveness among patients with cryptococcosis.
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Breakthrough invasive fungal infections: Who is at risk?
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Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis.
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Calcineurin governs thermotolerance and virulence of Cryptococcus gattii.
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Calcineurin is essential for survival during membrane stress in Candida albicans.
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Calcineurin promotes infection of the cornea by Candida albicans and can be targeted to enhance fluconazole therapy.
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Candida albicans reprioritizes metal handling during fluconazole stress.
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Candida glabrata fungemia in transplant patients receiving voriconazole after fluconazole.
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Candidal anastomotic infection in lung transplant recipients: successful treatment with a combination of systemic and inhaled antifungal agents.
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Candidemia in women with breast carcinoma treated with high-dose chemotherapy and autologous bone marrow transplantation.
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Caspofungin versus amphotericin B for invasive candidiasis.
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Clinical characteristics and response to prophylactic fluconazole of preterm VLBW neonates with baseline and acquired fungal colonisation in NICU: data from a multicentre RCT.
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Clinical effectiveness of posaconazole versus fluconazole as antifungal prophylaxis in hematology-oncology patients: a retrospective cohort study.
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Clonal and spontaneous origins of fluconazole resistance in Candida albicans.
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Colony size can be used to determine the MIC of fluconazole for pathogenic yeasts.
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Comparative cost-effectiveness analysis of voriconazole and fluconazole for prevention of invasive fungal infection in patients receiving allogeneic hematopoietic cell transplants.
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Comparison of itraconazole and fluconazole in treatment of cryptococcal meningitis and candida pyelonephritis in rabbits.
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Congenital candidiasis: an uncommon skin eruption presenting at birth.
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Copper Availability Influences the Transcriptomic Response of Candida albicans to Fluconazole Stress.
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Correlation of in vitro fluconazole resistance of Candida isolates in relation to therapy and symptoms of individuals seropositive for human immunodeficiency virus type 1.
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Cost-effectiveness of posaconazole versus fluconazole for prevention of invasive fungal infections in U.S. patients with graft-versus-host disease.
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Cost-effectiveness of posaconazole versus fluconazole or itraconazole in the prevention of invasive fungal infections among neutropenic patients in the United States.
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Could risk assessment for non-albicans Candida improve empiric treatment for invasive candidiasis?
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Cryptococcal meningitis in patients with glioma: a report of two cases.
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Cryptococcal meningoencephalitis: time for action.
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Cryptococcosis in human immunodeficiency virus-negative patients in the era of effective azole therapy.
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Cryptococcus neoformans methionine synthase: expression analysis and requirement for virulence.
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Cryptococcus neoformans phosphoinositide-dependent kinase 1 (PDK1) ortholog is required for stress tolerance and survival in murine phagocytes.
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Cryptococcus neoformans-Cryptococcus gattii species complex: an international study of wild-type susceptibility endpoint distributions and epidemiological cutoff values for fluconazole, itraconazole, posaconazole, and voriconazole.
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Cutaneous cryptococcosis in solid organ transplant recipients.
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Deletion of Cryptococcus neoformans AIF ortholog promotes chromosome aneuploidy and fluconazole-resistance in a metacaspase-independent manner.
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Dosing in neonates: special considerations in physiology and trial design.
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Dosing of Antimicrobials in the Neonatal Intensive Care Unit: Does Clinical Practice Reflect Pharmacokinetics-based Recommendations?
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Dynamic and heterogeneous mutations to fluconazole resistance in Cryptococcus neoformans.
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Editorial commentary: Fluconazole therapeutic drug monitoring in children with cancer: not today.
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Effect of fluconazole prophylaxis on Candida fluconazole susceptibility in premature infants.
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Effect of fluconazole prophylaxis on candidiasis and mortality in premature infants: a randomized clinical trial.
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Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence.
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Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo.
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External Evaluation of Two Fluconazole Infant Population Pharmacokinetic Models.
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First, do no harm.
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Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance.
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Fluconazole Prophylaxis for the Prevention of Candidiasis in Premature Infants: A Meta-analysis Using Patient-level Data.
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Fluconazole analogues with metal-binding motifs impact metal-dependent processes and demonstrate antifungal activity in Candida albicans.
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Fluconazole and Candida krusei fungemia.
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Fluconazole dosing for the prevention or treatment of invasive candidiasis in young infants.
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Fluconazole loading dose pharmacokinetics and safety in infants.
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Fluconazole pharmacokinetics and safety in premature infants.
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Fluconazole population pharmacokinetics and dosing for prevention and treatment of invasive Candidiasis in children supported with extracorporeal membrane oxygenation.
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Fluconazole prophylaxis for prevention of invasive candidiasis in infants.
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Fluconazole therapy for experimental cryptococcosis and candidiasis in the rabbit.
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Genotypic diversity and clinical outcome of cryptococcosis in renal transplant recipients in Brazil.
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Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease.
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Hepatic candidiasis: persistent pyrexia in a patient with acute myeloid leukaemia after recovery from consolidation therapy-induced neutropenia.
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Immunosuppressive and nonimmunosuppressive cyclosporine analogs are toxic to the opportunistic fungal pathogen Cryptococcus neoformans via cyclophilin-dependent inhibition of calcineurin.
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Immunotherapy with tacrolimus (FK506) does not select for resistance to calcineurin inhibitors in Candida albicans isolates from liver transplant patients.
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In Vitro and In Vivo Assessment of FK506 Analogs as Novel Antifungal Drug Candidates.
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In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus.
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In vitro and in vivo efficacies of the azole SCH56592 against Cryptococcus neoformans.
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In vitro and in vivo efficacies of the new triazole albaconazole against Cryptococcus neoformans.
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In-vitro activity of dicationic aromatic compounds and fluconazole against Cryptococcus neoformans and Candida spp.
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Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers.
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Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species.
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Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries.
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Management of injuries caused by Cryptococcus neoformans--contaminated needles.
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Neonatal candidiasis: prophylaxis and treatment.
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Non-comparative evaluation of the safety of aerosolized amphotericin B lipid complex in patients undergoing allogeneic hematopoietic stem cell transplantation.
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Old and new: appropriate dosing for neonatal antifungal drugs in the nursery.
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Oropharyngeal yeast flora and fluconazole resistance in HIV-infected patients receiving long-term continuous versus intermittent fluconazole therapy.
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Penetration of imidazoles and triazoles into cerebrospinal fluid of rabbits.
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Penetration of new azole compounds into the eye and efficacy in experimental Candida endophthalmitis.
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Persistence of the same Candida albicans strain despite fluconazole therapy. Documentation by pulsed-field gel electrophoresis.
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Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant.
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Pharmacokinetics and pharmacodynamics of fluconazole for cryptococcal meningoencephalitis: implications for antifungal therapy and in vitro susceptibility breakpoints.
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Pharmacokinetics and safety of fluconazole in young infants supported with extracorporeal membrane oxygenation.
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Pharmacotherapy of disseminated histoplasmosis in patients with AIDS.
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Phenotypic and genotypic evaluation of fluconazole resistance in vaginal Candida strains isolated from HIV-infected women from Brazil.
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Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on ECMO.
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Physiologically-Based Pharmacokinetic Modeling Characterizes the CYP3A-Mediated Drug-Drug Interaction Between Fluconazole and Sildenafil in Infants.
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Physiologically-Based Pharmacokinetic Modeling of Fluconazole Using Plasma and Cerebrospinal Fluid Samples From Preterm and Term Infants.
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Population Pharmacokinetics of Fluconazole in Premature Infants with Birth Weights Less than 750 Grams.
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Population pharmacokinetics of fluconazole in young infants.
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Population pharmacokinetics of sildenafil in extremely premature infants.
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Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia.
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Predictors and outcomes of Candida bloodstream infection: eight-year surveillance, western Saudi Arabia.
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Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation.
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Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method.
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Reduced Visual Acuity Following Kidney Stone Extraction.
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Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimally invasive and noninvasive probes for hepatic and first-pass CYP3A activity.
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Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase.
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Successful treatment of Trichosporon mucoides infection with fluconazole in a heart and kidney transplant recipient.
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Surgical infection prophylaxis prior to left ventricular assist device implantation: A survey of clinical practice.
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Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans.
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Synergistic effect of calcineurin inhibitors and fluconazole against Candida albicans biofilms.
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Targeting the calcineurin pathway enhances ergosterol biosynthesis inhibitors against Trichophyton mentagrophytes in vitro and in a human skin infection model.
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The calcineurin target, Crz1, functions in azole tolerance but is not required for virulence of Candida albicans.
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The pharmacokinetics of BAY R3783 and its efficacy in the treatment of experimental cryptococcal meningitis.
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Treatment of experimental cryptococcal meningitis and disseminated candidiasis with SCH39304.
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Treatment of lymphocutaneous and visceral sporotrichosis with fluconazole.
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Trehalose pathway as an antifungal target.
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Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans.
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Use of fluconazole in a patient with documented malabsorption of ketoconazole.
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Keywords of People