Genes, rev
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Subject Areas on Research
- An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys.
- Derivation of a biologically contained replication system for human immunodeficiency virus type 1.
- Effects of chimeric mutants of human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex on nucleolar targeting signals.
- HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency.
- Identification of cis-acting repressor activity within human immunodeficiency virus type 1 protease sequences.
- Identification of the activation domain of equine infectious anemia virus rev.
- Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization.
- Overexpression of RRE-derived sequences inhibits HIV-1 replication in CEM cells.
- Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference.
- Regulation of HIV-1 gene expression.
- Retroviruses as model systems for the study of nuclear RNA export pathways.
- Rev and the fate of pre-mRNA in the nucleus: implications for the regulation of RNA processing in eukaryotes.
- Structural and functional analysis of the visna virus Rev-response element.
- The HIV-1 Rev protein: prototype of a novel class of eukaryotic post-transcriptional regulators.
- The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence.