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Subject Areas on Research
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'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.
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(Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling.
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A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice.
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A Molecular Switch Regulating Cell Fate Choice between Muscle Progenitor Cells and Brown Adipocytes.
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A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease.
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A balancing act: RNA binding protein HuR/TTP axis in endometriosis patients.
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A macrophage subpopulation recruited by CC chemokine ligand-2 clears apoptotic cells in noninfectious lung injury.
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A mathematical model of the folate cycle: new insights into folate homeostasis.
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A new prostate cancer therapeutic approach: combination of androgen ablation with COX-2 inhibitor.
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A novel approach to maintain gut mucosal integrity using an oral enzyme supplement.
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A pentapeptide monocyte locomotion inhibitory factor protects brain ischemia injury by targeting the eEF1A1/endothelial nitric oxide synthase pathway.
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A reappraisal of loop diuretic choice in heart failure patients.
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A spatially and temporally restricted mouse model of soft tissue sarcoma.
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A unifying hypothesis to explain the retardation of aging and tumorigenesis by caloric restriction.
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A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis.
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Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling.
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Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract.
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Acadesine inhibits neutrophil CD11b up-regulation in vitro and during in vivo cardiopulmonary bypass.
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Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression.
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Activation and cross-talk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78.
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Activation of Galpha q-coupled signaling pathways in glomerular podocytes promotes renal injury.
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Activation of Nrf2 Pathway Contributes to Neuroprotection by the Dietary Flavonoid Tiliroside.
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Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal Staphylococcus aureus sepsis.
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Activation of src-family tyrosine kinases by LPS regulates cytokine production in dendritic cells by controlling AP-1 formation.
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Acute pancreatitis induces FasL gene expression and apoptosis in the liver.
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Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells.
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Administration of nicotine to adolescent rats evokes regionally selective upregulation of CNS alpha 7 nicotinic acetylcholine receptors.
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Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy.
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Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase.
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Adrenergic receptors in premenstrual dysphoric disorder. II. Neutrophil beta2-adrenergic receptors: Gs protein coupling, phase of menstrual cycle and prediction of luteal phase symptom severity.
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Advancing biomarker science in the 21st century.
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Aging enhances the basal production of IL-6 and CCL2 in vascular smooth muscle cells.
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Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies.
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Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.
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Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells.
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Allelic exclusion of mouse T cell receptor alpha chains occurs at the time of thymocyte TCR up-regulation.
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Alpha7 nicotinic acetylcholine receptors targeted by cholinergic developmental neurotoxicants: nicotine and chlorpyrifos.
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Alterations of serotonin synaptic proteins in brain regions of neonatal Rhesus monkeys exposed to perinatal environmental tobacco smoke.
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Altered T-dependent antigen responses and development of autoimmune symptoms in mice lacking E2A in T lymphocytes.
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Altered prefrontal dopaminergic function in chronic recreational ketamine users.
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Ameroid constrictor versus hydraulic occluder: creation of hibernating myocardium.
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Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer.
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Amplification of HER-2/neu gene in human gastric adenocarcinomas: correlation with primary site.
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An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer.
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An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models.
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Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.
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Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/paracrine factors.
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Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin.
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Angiotensin II-induced MMP-2 activity and MMP-14 and basigin protein expression are mediated via the angiotensin II receptor type 1-mitogen-activated protein kinase 1 pathway in retinal pigment epithelium: implications for age-related macular degeneration.
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Ank3-dependent SVZ niche assembly is required for the continued production of new neurons.
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Anomalous regulation of beta-adrenoceptor signaling in brain regions of the newborn rat.
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Antibody binding to a conformation-dependent epitope induces L-selectin association with the detergent-resistant cytoskeleton.
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Antibody to E- and L-selectin does not prevent lung injury or mortality in septic baboons.
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Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish.
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Apolipoprotein E and peptide mimetics modulate inflammation by binding the SET protein and activating protein phosphatase 2A.
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Apolipoprotein E modifies the CNS response to injury via a histamine-mediated pathway.
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Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal.
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Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier.
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Association Between Blood Lead Level and Uncontrolled Hypertension in the US Population (NHANES 1999-2016).
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Association of chronic congestive heart failure in humans with an intrinsic upregulation in skeletal muscle sarcoplasmic reticulum calcium ion adenosine triphosphatase activity.
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Association of serum phosphorus level with anemia in kidney transplant recipients.
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Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling.
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Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis.
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Bacterial infection of osteoblasts induces interleukin-1beta and interleukin-18 transcription but not protein synthesis.
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Basic fibroblast growth factor is upregulated in hibernating myocardium.
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Bcl-xL is an oncogenic driver in colorectal cancer.
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Beet the Best?
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Beta-catenin mediates soft tissue contracture in clubfoot.
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Biology of cerebral arteriovenous malformations with a focus on inflammation.
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Biomanufacturing organized collagen-based microfibers as a Tissue ENgineered Device (TEND) for tendon regeneration.
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Biomarkers, mineralocorticoid receptor antagonism, and cardiorenal remodeling.
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Blocking CCR7 at the ocular surface impairs the pathogenic contribution of dendritic cells in allergic conjunctivitis.
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Blood pressure homeostasis is maintained by a P311-TGF-β axis.
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Blood transfusions are associated with urinary biomarkers of kidney injury in cardiac surgery.
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Blood-derived macrophages infiltrate the retina and activate Muller glial cells under experimental choroidal neovascularization.
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Bombesin-like peptide and receptors in lung injury models: diverse gene expression, similar function.
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Bone Marrow Mesenchymal Stem Cell Transplantation Increases GAP-43 Expression via ERK1/2 and PI3K/Akt Pathways in Intracerebral Hemorrhage.
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Bone morphogenetic proteins induce pancreatic cancer cell invasiveness through a Smad1-dependent mechanism that involves matrix metalloproteinase-2.
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Brain nicotinic acetylcholine receptor availability and response to smoking cessation treatment: a randomized trial.
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Bronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression.
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CBX3/HP1γ promotes tumor proliferation and predicts poor survival in hepatocellular carcinoma.
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CD19 regulates the development of bleomycin-induced pulmonary fibrosis in a mouse model.
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CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.
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CS-4,6 is differentially upregulated in glial scar and is a potent inhibitor of neurite extension.
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CXCL10 is upregulated in synovium and cartilage following articular fracture.
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CXCL12 prolongs naive CD4+ T lymphocytes survival via activation of PKA, CREB and Bcl2 and BclXl up-regulation.
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Ca2+/calmodulin-dependent protein kinase type IV in dorsal root ganglion: colocalization with peptides, axonal transport and effect of axotomy.
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CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells.
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Calcium dependent CAMTA1 in adult stem cell commitment to a myocardial lineage.
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Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial.
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Cardiac catheterization within 1 to 3 days of proximal aortic surgery is not associated with increased postoperative acute kidney injury.
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Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart.
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Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia.
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Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension.
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Cells en route to apoptosis are characterized by the upregulation of c-fos, c-myc, c-jun, cdc2, and RB phosphorylation, resembling events of early cell-cycle traverse.
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Changes in novel biomarkers of disease activity in juvenile and adult dermatomyositis are sensitive biomarkers of disease course.
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Changes in tumour expression of programmed death-ligand 1 after neoadjuvant concurrent chemoradiotherapy in patients with squamous oesophageal cancer.
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Characterization of the PC4 binding domain and its interactions with HNF4alpha.
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Chemoattractant receptor-induced phosphorylation of L-selectin.
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Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide.
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Chronic activation of the kinase IKKβ impairs T cell function and survival.
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Chronic ethanol intoxication enhances the production of cytokine-induced neutrophil chemoattractant and macrophage inflammatory protein-2 by hepatocytes after human immunodeficiency virus-1 glycoprotein 120 vaccination.
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Chronic prenatal nicotine exposure sensitizes rat brain to acute postnatal nicotine challenge as assessed with ornithine decarboxylase.
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Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.
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Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration.
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Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma.
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Cloning and characterization of a novel endothelial promoter of the human CYP19 (aromatase P450) gene that is up-regulated in breast cancer tissue.
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Coadministration of IL-12 or IL-10 expression cassettes drives immune responses toward a Th1 phenotype.
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Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool.
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Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity.
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Combined PI3K/Akt and Smad2 Activation Promotes Corneal Endothelial Cell Proliferation.
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Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells.
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Common cancer biomarkers.
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Comparative transcriptome analysis reveals novel roles of the Ras and cyclic AMP signaling pathways in environmental stress response and antifungal drug sensitivity in Cryptococcus neoformans.
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Complement activation contributes to perioperative neurocognitive disorders in mice.
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Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
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Connective tissue growth factor-mediated upregulation of neuromedin U expression in trabecular meshwork cells and its role in homeostasis of aqueous humor outflow.
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Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice.
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Consequences of unilateral hearing loss: time dependent regulation of protein synthesis in auditory brainstem nuclei.
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Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms.
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Conserved and divergent expression dynamics during early patterning of the telencephalon in mouse and chick embryos.
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Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation.
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Contracture and transient receptor potential channel upregulation in the anterior glenohumeral joint capsule of patients with end-stage osteoarthritis.
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Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1.
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Cooperation between transcription factor AP-1 and NF-kappaB in the induction of interleukin-8 in human pancreatic adenocarcinoma cells by hypoxia.
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Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation.
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Copper signaling axis as a target for prostate cancer therapeutics.
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Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.
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Coronavirus Disease 2019 and Hypertension: The Role of Angiotensin-Converting Enzyme 2 and the Renin-Angiotensin System.
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Correlates of osteoprotegerin and association with aortic pulse wave velocity in patients with chronic kidney disease.
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Correlating notch signaling with thymocyte maturation.
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Creatine kinase overexpression improves ATP kinetics and contractile function in postischemic myocardium.
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Critical prenatal and postnatal periods for persistent effects of dexamethasone on serotonergic and dopaminergic systems.
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Curcumin inhibits LPS-induced CCL2 expression via JNK pathway in C6 rat astrocytoma cells.
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Cyclin D1 overexpression and response to bortezomib treatment in a breast cancer model.
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Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes.
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Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer.
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Cytokines and adhesion molecules in the pathogenesis of vasculitis.
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Cytokines in murine lyme carditis: Th1 cytokine expression follows expression of proinflammatory cytokines in a susceptible mouse strain.
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Cytosolic branched chain aminotransferase (BCATc) mRNA is up-regulated in restricted brain areas of BDNF transgenic mice.
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Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28.
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DHX15 is up-regulated in castration-resistant prostate cancer and required for androgen receptor sensitivity to low DHT concentrations.
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DNA methyltransferase levels and altered CpG methylation in the total genome and in the GSTP1 gene in human glioma cells transfected with sense and antisense DNA methyltransferase cDNA.
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Dehydroascorbate transport in human chondrocytes is regulated by hypoxia and is a physiologically relevant source of ascorbic acid in the joint.
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Derlin-1 is overexpressed in non-small cell lung cancer and promotes cancer cell invasion via EGFR-ERK-mediated up-regulation of MMP-2 and MMP-9.
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Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis.
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Design of a phase 2b trial of intracoronary administration of AAV1/SERCA2a in patients with advanced heart failure: the CUPID 2 trial (calcium up-regulation by percutaneous administration of gene therapy in cardiac disease phase 2b).
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Destabilization of the VCP-Ufd1-Npl4 complex is associated with decreased levels of ERAD substrates.
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Determination of an angiotensin II-regulated proteome in primary human kidney cells by stable isotope labeling of amino acids in cell culture (SILAC).
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Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.
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Developmental Neurotoxicity of Tobacco Smoke Directed Toward Cholinergic and Serotonergic Systems: More Than Just Nicotine.
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Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio).
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Diacetyl induces amphiregulin shedding in pulmonary epithelial cells and in experimental bronchiolitis obliterans.
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Dietary intake of palmitate and oleate has broad impact on systemic and tissue lipid profiles in humans.
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Different effects of glucose starvation on expression and stability of VEGF mRNA isoforms in murine ovarian cancer cells.
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Differential cardiac gene expression during cardiopulmonary bypass: ischemia-independent upregulation of proinflammatory genes.
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Differential collagen I gene expression in fetal fibroblasts.
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Differential development of cholinergic nerve terminal markers in rat brain regions: implications for nerve terminal density, impulse activity and specific gene expression.
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Differential expression of systemic inflammatory mediators in amputees with chronic residual limb pain.
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Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior.
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Differential regulation of genes by retrotransposons in rice promoters.
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Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer.
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Direct vaccination with tumor cells killed with ICP4-deficient HSVd120 elicits effective antitumor immunity.
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Dishevelled-3 activates p65 to upregulate p120-catenin transcription via a p38-dependent pathway in non-small cell lung cancer.
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Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death.
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Disruption of the Ang II type 1 receptor promotes longevity in mice.
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Dissecting the roles of DR4, DR5 and c-FLIP in the regulation of geranylgeranyltransferase I inhibition-mediated augmentation of TRAIL-induced apoptosis.
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Distal-Less Homeobox 5 Is a Therapeutic Target for Attenuating Hypertrophy and Apoptosis of Mesenchymal Progenitor Cells.
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Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.
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Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain.
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Distribution and functional significance of cardiac angiotensin converting enzyme in hypertrophied rat hearts.
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Distribution, levels and phosphorylation of Raf-1 in Alzheimer's disease.
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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling.
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Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13.
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Dll4 Inhibition plus Aflibercept Markedly Reduces Ovarian Tumor Growth.
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Does a rise in plasma erythropoietin after high-altitude exposure affect FGF23 in healthy volunteers on a normal or low-phosphorus diet?
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Down-regulation of neu/HER-2 by interferon-gamma in prostate cancer cells.
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Down-regulation of the orphan nuclear receptor ROR gamma t is essential for T lymphocyte maturation.
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Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch.
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Dysregulated activation of fetal liver programme in acute liver failure.
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Dysregulation of the miR-30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication.
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E protein transcription factors are required for the development of CD4(+) lineage T cells.
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E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene.
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E-Cadherin Represses Anchorage-Independent Growth in Sarcomas through Both Signaling and Mechanical Mechanisms.
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E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program.
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EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer.
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ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells.
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ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity.
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Early B-cell activation after West Nile virus infection requires alpha/beta interferon but not antigen receptor signaling.
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Early effects of imatinib mesylate on the expression of insulin-like growth factor binding protein-3 and positron emission tomography in patients with gastrointestinal stromal tumor.
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Early trends in serum phosphate and creatinine levels are associated with mortality following major hepatectomy.
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Effect of UV-B phototherapy on plasma HIV type 1 RNA viral level: a self-controlled prospective study.
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Effect of ionizing radiation on thymidine uptake, differentiation, and VEGFR2 receptor expression in endothelial cells: the role of VEGF(165).
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Effect of randomized serum progesterone concentration on secretory endometrial histologic development and gene expression.
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Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors.
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Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.
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Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy--Cancer and Leukemia Group B Trial 30203.
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Electrical stimulation of neonatal cardiac myocytes activates the NFAT3 and GATA4 pathways and up-regulates the adenylosuccinate synthetase 1 gene.
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Elevated levels of adrenomedullin in eutopic endometrium and plasma from women with endometriosis.
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Elevated nitric oxide production in children with malarial anemia: hemozoin-induced nitric oxide synthase type 2 transcripts and nitric oxide in blood mononuclear cells.
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Emergence of simian immunodeficiency virus-specific cytotoxic CD4+ T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency virus.
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Encapsulation and controlled release of retinol from silicone particles for topical delivery.
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Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model.
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Endotoxin-mediated nitric oxide synthesis inhibits IL-1beta gene transcription in ANA-1 murine macrophages.
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Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach.
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Enhanced Th17-cell responses render CCR2-deficient mice more susceptible for autoimmune arthritis.
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Enhanced Uterine Contractility and Stillbirth in Mice Lacking G Protein-Coupled Receptor Kinase 6 (GRK6): Implications for Oxytocin Receptor Desensitization.
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Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice.
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Enhanced expression of cytokines and chemokines by blood monocytes to in vitro lipopolysaccharide stimulation are associated with hostility and severity of depressive symptoms in healthy women.
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Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cells.
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Enrichment of putative prostate cancer stem cells after androgen deprivation: upregulation of pluripotency transactivators concurs with resistance to androgen deprivation in LNCaP cell lines.
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Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression.
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Epigallocatechin-3-Gallate Upregulates miR-221 to Inhibit Osteopontin-Dependent Hepatic Fibrosis.
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Equalizing cDNA subtraction based on selective suppression of polymerase chain reaction: cloning of Jurkat cell transcripts induced by phytohemaglutinin and phorbol 12-myristate 13-acetate.
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Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium.
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Estrogen up-regulates cyclooxygenase-2 via estrogen receptor in human uterine microvascular endothelial cells.
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Ethylenecarbodiimide-treated splenocytes carrying male CD4 epitopes confer histocompatibility Y chromosome antigen transplant protection by inhibiting CD154 upregulation.
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Evaluation of CD86/CD28 and CD40/CD154 pathways in regulating monocyte-derived CD80 expression during their interaction with allogeneic endothelium.
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Evaluation of Urine Aquaporin-1 and Perilipin-2 Concentrations as Biomarkers to Screen for Renal Cell Carcinoma: A Prospective Cohort Study.
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Evidence That an Unconventional Actin Can Provide Essential F-Actin Function and That a Surveillance System Monitors F-Actin Integrity in Chlamydomonas.
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Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement.
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Exacerbation of established pulmonary fibrosis in a murine model by gammaherpesvirus.
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Exacerbation of systemic inflammation and increased cerebral infarct volume with cardiopulmonary bypass after focal cerebral ischemia in the rat.
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Examination of Potential Modifiers of the Association of APOL1 Alleles with CKD Progression.
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Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction.
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Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection.
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Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain.
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Expression and modulation of RPE cell membrane complement regulatory proteins.
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Expression of E-selectin messenger RNA and protein in rheumatoid arthritis.
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Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain.
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Expression of cell-adhesion molecules in the salivary gland microenvironment of Sjögren's syndrome.
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Expression of heme oxygenase-1 in the lung in chronic hypoxia.
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Expression of mRNAs, miRNAs, and lncRNAs in Human Trabecular Meshwork Cells Upon Mechanical Stretch.
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Expression of proliferation-specific genes in the mucosa adjacent to colon carcinoma.
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Expression of terminin in the rat brain during neuronal differentiation.
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Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma.
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Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion.
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Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women.
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Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion.
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FAK overexpression and p53 mutations are highly correlated in human breast cancer.
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FGF-23 levels in patients with AKI and risk of adverse outcomes.
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FGF23 and Left Ventricular Hypertrophy in Children with CKD.
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FGFR2 in gastric cancer: protein overexpression predicts gene amplification and high H-index predicts poor survival.
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FIH-1-modulated HIF-1α C-TAD promotes acute kidney injury to chronic kidney disease progression via regulating KLF5 signaling.
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FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
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Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-κB-dependent pathways.
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Fas/FasL play a central role in pancreatitis-induced hepatocyte apoptosis.
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Fetal chlorpyrifos exposure: adverse effects on brain cell development and cholinergic biomarkers emerge postnatally and continue into adolescence and adulthood.
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Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues.
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Fibroblast Growth Factor 23 and Incident Cardiovascular Disease and Mortality in Middle-Aged Adults.
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Fibroblast Growth Factor 23 and Kidney Disease Progression in Autosomal Dominant Polycystic Kidney Disease.
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Fibroblast Growth Factor-23, Heart Failure Risk, and Renin-Angiotensin-Aldosterone-System Blockade in Hypertension: The MESA Study.
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Fibroblast growth factor 23 and incident CKD in type 2 diabetes.
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Fibroblast growth factor 23 and the future of phosphorus management.
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Fibroblast growth factor 23 in patients undergoing peritoneal dialysis.
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Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease.
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Fibroblast growth factor 23 is not associated with and does not induce arterial calcification.
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Fibronectin Extra Domain A Promotes Liver Sinusoid Repair following Hepatectomy.
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Fine ambient particles induce oxidative stress and metal binding genes in human alveolar macrophages.
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Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes.
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Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations.
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Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis.
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Foxo-dependent Par-4 Upregulation Prevents Long-term Survival of Residual Cells Following PI3K-Akt Inhibition.
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Fragile X males with unmethylated, full mutation trinucleotide repeat expansions have elevated levels of FMR1 messenger RNA.
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Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line.
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G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization.
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G protein-coupled receptor kinase 5 in cultured vascular smooth muscle cells and rat aorta. Regulation by angiotensin II and hypertension.
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G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal.
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GPI-defective monocytes from paroxysmal nocturnal hemoglobinuria patients show impaired in vitro dendritic cell differentiation.
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GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain.
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GW112, a novel antiapoptotic protein that promotes tumor growth.
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Gallbladder Na+/H+ exchange activity is up-regulated prior to cholesterol crystal formation.
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Gene expression and survival changes in Saccharomyces cerevisiae during suspension culture.
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Gene expression during normal and FSHD myogenesis.
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Gene expression in obliterative bronchiolitis-like lesions in 2,3-pentanedione-exposed rats.
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Gene expression profile in circulating mononuclear cells after exposure to ultrafine carbon particles.
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Gene expression profiling in RAS oncogene-transformed cell lines and in solid tumors using subtractive suppression hybridization and cDNA arrays.
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Gene expression profiling of mouse bladder inflammatory responses to LPS, substance P, and antigen-stimulation.
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Gene products promoting remyelination are up-regulated in a cell therapy product manufactured from banked human cord blood.
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Gene up-regulation in heart during mammalian hibernation.
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Genetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model.
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Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner.
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Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue.
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Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes.
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Gi-biased β2AR signaling links GRK2 upregulation to heart failure.
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Global analysis of gene expression in renal ischemia-reperfusion in the mouse.
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Glutamine attenuates lung injury and improves survival after sepsis: role of enhanced heat shock protein expression.
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Glutamine-mediated dual regulation of heat shock transcription factor-1 activation and expression.
-
Gq-dependent signaling upregulates COX2 in glomerular podocytes.
-
Growth factor control of extracellular proteolysis.
-
Growth factor receptors expression in anaplastic thyroid carcinoma: potential markers for therapeutic stratification.
-
HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis.
-
HIF-1 Alpha Regulates the Response of Primary Sarcomas to Radiation Therapy through a Cell Autonomous Mechanism.
-
HIV-1 infection initiates an inflammatory cascade in human renal tubular epithelial cells.
-
HSV oncolytic therapy upregulates interferon-inducible chemokines and recruits immune effector cells in ovarian cancer.
-
Hedgehog Signaling is Associated with Liver Response to Fractionated Irradiation in Mice.
-
Hedgehog regulates yes-associated protein 1 in regenerating mouse liver.
-
Hedgehog signaling in human medullary thyroid carcinoma: a novel signaling pathway.
-
Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation.
-
Helicobacter pylori-induced Th17 responses modulate Th1 cell responses, benefit bacterial growth, and contribute to pathology in mice.
-
Heme: a novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms.
-
Hemoglobin-induced endothelial cell permeability is controlled, in part, via a myeloid differentiation primary response gene-88-dependent signaling mechanism.
-
Heparin-binding epidermal growth factor-like growth factor promotes neuroblastoma differentiation.
-
Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
-
Heterogeneity of glycolysis in cancers and therapeutic opportunities.
-
Heterologous expression, and biochemical and cellular characterization of CaPLA1 encoding a hot pepper phospholipase A1 homolog.
-
High relative deoxyribonucleic acid content of trophectoderm biopsy adversely affects pregnancy outcomes.
-
High-Mobility Group Box-1 Is Associated With Obesity, Inflammation, and Subclinical Cardiovascular Risk Among Young Adults: A Longitudinal Cohort Study.
-
High-Sensitivity Troponin I and Coronary Computed Tomography in Symptomatic Outpatients With Suspected CAD: Insights From the PROMISE Trial.
-
High-Sensitivity Troponin I in Hospitalized and Ambulatory Patients With Heart Failure With Preserved Ejection Fraction: Insights From the Heart Failure Clinical Research Network.
-
Higher aldosterone and lower N-terminal proatrial natriuretic peptide as biomarkers of salt sensitivity in the community.
-
Higher high-density lipoprotein cholesterol in African-American women with polycystic ovary syndrome compared with Caucasian counterparts.
-
Homeobox genes Hoxd3 and Hoxd8 are differentially expressed in fetal mouse excisional wounds.
-
Human epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomas.
-
Human uterine NK cells interact with uterine macrophages via NKG2D upon stimulation with PAMPs.
-
Hyaluronan interactions with innate immunity in lung biology.
-
Hypo-CpG methylation controls PTEN expression and cell apoptosis in irradiated lung.
-
Hypoxia reprograms calcium signaling and regulates myoglobin expression.
-
Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores.
-
Hypoxic Gene Expression of Donor Bronchi Linked to Airway Complications after Lung Transplantation.
-
ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration.
-
IFN-beta inhibits human Th17 cell differentiation.
-
IFN-beta1a inhibits the secretion of Th17-polarizing cytokines in human dendritic cells via TLR7 up-regulation.
-
IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response.
-
IL-10 induces regulatory T cell apoptosis by up-regulation of the membrane form of TNF-alpha.
-
IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy.
-
ITGA1 is upregulated in response to oxygen over time in a BMP4 model of trophoblast.
-
Ibudilast sensitizes glioblastoma to temozolomide by targeting Macrophage Migration Inhibitory Factor (MIF).
-
Identification of a human heme exporter that is essential for erythropoiesis.
-
Identification of differentially expressed microRNAs in human hepatocellular adenoma associated with type I glycogen storage disease: a potential utility as biomarkers.
-
Identification of novel cellular targets in biliary tract cancers using global gene expression technology.
-
Identification of novel mediators of NF-kappaB through genome-wide survey of monocyte adherence-induced genes.
-
Immunomodulation of human CD8⁺ T cells by thymoglobulin in vitro.
-
Immunomodulator effect of picroliv and its potential in treatment against resistant Plasmodium yoelii (MDR) infection in mice.
-
Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma.
-
Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular endothelial growth factor receptor 1.
-
In vitro and in vivo effects of leukotriene B4 antagonism in a primate model of asthma.
-
In vivo molecular analysis of cytokines in a murine model of ocular onchocerciasis. I. Up-regulation of IL-4 and IL-5 mRNAs and not IL-2 and IFN gamma mRNAs in the cornea due to experimental interstitial keratitis.
-
In vivo regulation of hTERT expression and telomerase activity by androgen.
-
Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease.
-
Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression.
-
Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6.
-
Increased expression of anti-apoptosis genes in peripheral blood cells from patients with paroxysmal nocturnal hemoglobinuria.
-
Increased expression of estrogen receptor beta in pachytene spermatocytes after short-term methoxyacetic acid administration.
-
Increased expression of p130 in Alzheimer disease.
-
Increased expression of senescence markers in cystic fibrosis airways.
-
Increased renal dopamine and acute renal adaptation to a high-phosphate diet.
-
Increasing atmospheric CO2 reduces metabolic and physiological differences between isoprene- and non-isoprene-emitting poplars.
-
Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced transmembrane calcium flux.
-
Induction of hippocampal long-term potentiation during waking leads to increased extrahippocampal zif-268 expression during ensuing rapid-eye-movement sleep.
-
Induction of protein secretory pathway is required for systemic acquired resistance.
-
Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation.
-
Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.
-
Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5.
-
Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease.
-
Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis.
-
Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.
-
Inhibition of Wnt6 by Sfrp2 regulates adult cardiac progenitor cell differentiation by differential modulation of Wnt pathways.
-
Inhibition of matrix metalloproteinases enhances in vitro repair of the meniscus.
-
Inhibition of radiation-induced up-regulation of leukocyte adhesion to endothelial cells with the platelet-activating factor inhibitor, BN52021.
-
Inhibition of thioredoxin activates mitophagy and overcomes adaptive bortezomib resistance in multiple myeloma.
-
Interaction of human mesenchymal stem cells with disc cells: changes in extracellular matrix biosynthesis.
-
Intercellular adhesion molecule-1 deficiency attenuates the development of skin fibrosis in tight-skin mice.
-
Interferon regulatory factor-1 up-regulates angiotensin II type 2 receptor and induces apoptosis.
-
Interferon regulatory factors regulate interleukin-1beta-converting enzyme expression and apoptosis in vascular smooth muscle cells.
-
Interleukin-1 stimulates the beta-amyloid precursor protein promoter.
-
Intradiscal injection of simvastatin results in radiologic, histologic, and genetic evidence of disc regeneration in a rat model of degenerative disc disease.
-
Invasive prostate carcinoma driven by c-Src and androgen receptor synergy.
-
Ischemic Stroke with Troponin Elevation: Patient Characteristics, Resource Utilization, and In-Hospital Outcomes.
-
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism.
-
JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain.
-
Ketamine up-regulates a cluster of intronic miRNAs within the serotonin receptor 2C gene by inhibiting glycogen synthase kinase-3.
-
Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.
-
L-Threonine induces heat shock protein expression and decreases apoptosis in heat-stressed intestinal epithelial cells.
-
LIN28B promotes the development of neuroendocrine prostate cancer.
-
LPS elicits a much larger and broader inflammatory response than Escherichia coli infection within the hippocampus of neonatal rats.
-
Lactose supports Muller cell protein expression patterns in the absence of the retinal pigment epithelium.
-
Lasting effects of developmental dexamethasone treatment on neural cell number and size, synaptic activity, and cell signaling: critical periods of vulnerability, dose-effect relationships, regional targets, and sex selectivity.
-
Lens fiber cell elongation and differentiation is associated with a robust increase in myosin light chain phosphorylation in the developing mouse.
-
Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury.
-
Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function.
-
Ligand-induced overexpression of a constitutively active beta2-adrenergic receptor: pharmacological creation of a phenotype in transgenic mice.
-
Ligation of cell surface-associated glucose-regulated protein 78 by receptor-recognized forms of alpha 2-macroglobulin: activation of p21-activated protein kinase-2-dependent signaling in murine peritoneal macrophages.
-
Ligation of prostate cancer cell surface GRP78 activates a proproliferative and antiapoptotic feedback loop: a role for secreted prostate-specific antigen.
-
Lipopolysaccharide up-regulates platelet-derived growth factor (PDGF) alpha-receptor expression in rat lung myofibroblasts and enhances response to all PDGF isoforms.
-
Lipopolysaccharide upregulates bradykinin 1 receptors in the isolated mouse bladder.
-
LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism.
-
Localized increase of chemokines in the lumen of human cerebral aneurysms.
-
Long-lasting CNS effects of a short-term chemical knockout of ornithine decarboxylase during development: nicotinic cholinergic receptor upregulation and subtle macromolecular changes in adulthood.
-
Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy.
-
Loss of sarcomeric proteins via upregulation of JAK/STAT signaling underlies interferon-γ-induced contractile deficit in engineered human myocardium.
-
Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds.
-
Low K+ promotes NF-kappaB/DNA binding in neuronal apoptosis induced by K+ loss.
-
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.
-
Lymphangitis after self-administration of lipopolysaccharide.
-
Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine.
-
Macrophage imbalance (M1 vs. M2) and upregulation of mast cells in wall of ruptured human cerebral aneurysms: preliminary results.
-
Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: an epithelial-stromal interaction in breast tumors mediated by CCAAT/enhancer binding protein beta.
-
Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion.
-
Manipulating large-scale Arabidopsis microarray expression data: identifying dominant expression patterns and biological process enrichment.
-
Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-Low Induction of Therapy Resistance.
-
Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis.
-
Mechanisms of resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea in human medulloblastoma and rhabdomyosarcoma.
-
Mesenchymal-Epithelial Transition in Sarcomas Is Controlled by the Combinatorial Expression of MicroRNA 200s and GRHL2.
-
Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells.
-
MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation.
-
Microglia in Pain: Detrimental and Protective Roles in Pathogenesis and Resolution of Pain.
-
Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration.
-
Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1.
-
Mitochondrial Oxidative Phosphorylation Complex Regulates NLRP3 Inflammasome Activation and Predicts Patient Survival in Nasopharyngeal Carcinoma.
-
Mitochondrial adaptations to obesity-related oxidant stress.
-
Mitogen-activated protein kinase (MAPK) hyperactivation and enhanced NRAS expression drive acquired vemurafenib resistance in V600E BRAF melanoma cells.
-
Modulation of Xenopus oocyte-expressed phospholemman-induced ion currents by co-expression of protein kinases.
-
Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78.
-
Molecular characterization of the tumor-suppressive function of nischarin in breast cancer.
-
Molecular footprint of Medawar's mutation accumulation process in mammalian aging.
-
Molecular interactions of B-CAM (basal-cell adhesion molecule) and laminin in epithelial skin cancer.
-
Molecular markers in ductal carcinoma in situ of the breast.
-
Monitoring changes in gene expression in renal ischemia-reperfusion in the rat.
-
Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas.
-
Multiple signals are required for maturation of human dendritic cells mobilized in vivo with Flt3 ligand.
-
Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I.
-
Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion.
-
Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS.
-
Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signatures.
-
Myocardial overexpression of adrenergic receptors and receptor kinases.
-
N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ATM pathway.
-
NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase.
-
Negative regulation of lymphocyte activation by the adaptor protein LAX.
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Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization.
-
Neonatal chronic hind paw inflammation alters sensitization to intradermal capsaicin in adult rats: a behavioral and immunocytochemical study.
-
Netrin-1-mediated axon guidance in mouse embryonic stem cells overexpressing neurogenin-1.
-
Neural input and the development of adrenergic intracellular signaling: neonatal denervation evokes neither receptor upregulation nor persistent supersensitivity of adenylate cyclase.
-
Neurotrophic factor-α1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone.
-
New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 2): Identification of nephrotoxic metabolites.
-
Nicotinic acetylcholine receptor expression and susceptibility to cholinergic immunomodulation in human monocytes of smoking individuals.
-
Nitric oxide donors protect murine myocardium against infarction via modulation of mitochondrial permeability transition.
-
Nitrous oxide anesthesia and plasma homocysteine in adolescents.
-
Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors.
-
Non-erythroid effects of erythropoietin.
-
Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity.
-
Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node.
-
Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork.
-
Nuclear factor-kappaB mediates Kupffer cell apoptosis through transcriptional activation of Fas/FasL.
-
Oestrogen receptors enhance dopamine neurone survival in rat midbrain.
-
Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression.
-
Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4.
-
Ontogeny of seizure-induced increases in BDNF immunoreactivity and TrkB receptor activation in rat hippocampus.
-
Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of early growth response-1 and platelet-derived growth factor ligands in pulmonary fibroblasts.
-
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
-
Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni.
-
Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis.
-
Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis.
-
Osteopontin is up-regulated in chronic hepatitis C and is associated with cellular permissiveness for hepatitis C virus replication.
-
Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice.
-
Osteopontin up-regulates critical epithelial-mesenchymal transition transcription factors to induce an aggressive breast cancer phenotype.
-
Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells.
-
Overexpressed BAG3 is a potential therapeutic target in chronic lymphocytic leukemia.
-
Overexpression of CRKL correlates with poor prognosis and cell proliferation in non-small cell lung cancer.
-
Overexpression of decoy receptor 3 in precancerous lesions and adenocarcinoma of the esophagus.
-
Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases: immunohistochemistry and real-time PCR analyses.
-
Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function.
-
Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma.
-
Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study.
-
Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy.
-
Oxygen-induced mitochondrial biogenesis in the rat hippocampus.
-
PCK1 regulates neuroendocrine differentiation in a positive feedback loop of LIF/ZBTB46 signalling in castration-resistant prostate cancer.
-
PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue.
-
PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice.
-
PILAR is a novel modulator of human T-cell expansion.
-
PSORS2 is due to mutations in CARD14.
-
PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP.
-
Paradoxical effects of a stress signal on pro- and anti-apoptotic machinery in HTLV-1 Tax expressing cells.
-
Patients with acute and chronic coronary syndromes have elevated long-term thrombin generation.
-
Pattern of liver enzyme elevations in acute ST-elevation myocardial infarction.
-
Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells.
-
Perinatal diazinon exposure compromises the development of acetylcholine and serotonin systems.
-
Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain.
-
Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate.
-
Peritoneal and subperitoneal stroma may facilitate regional spread of ovarian cancer.
-
Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.
-
Phospho-MED1-enhanced UBE2C locus looping drives castration-resistant prostate cancer growth.
-
Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4alpha transcriptional activity.
-
Pleiotropic roles of the Msi1-like protein Msl1 in Cryptococcus neoformans.
-
Point sources of Schwann cells result in growth into a nerve entubulation repair site in the absence of axons: effects of freeze-thawing.
-
Positive regulation of the vitamin D receptor by its cognate ligand in heterologous expression systems.
-
Post-transcriptional regulation of transcript abundance by a conserved member of the tristetraprolin family in Candida albicans.
-
Postnatal alterations in beta-adrenergic receptor binding in rat brain regions after continuous prenatal exposure to propranolol via maternal infusion.
-
Predictors of increased PaCO2 during immersed prone exercise at 4.7 ATA.
-
Pregnancy and estradiol modulate myometrial G-protein pathways in the guinea pig.
-
Prenatal stress elicits regionally selective changes in basal FGF-2 gene expression in adulthood and alters the adult response to acute or chronic stress.
-
Pressure overload selectively up-regulates Ca2+/calmodulin-dependent protein kinase II in vivo.
-
Pretreatment with an inhibitor of mac-1 alters regional and systemic platelet function during ischemia-reperfusion in swine.
-
Prevalence and incidence of liver enzyme elevations in a pooled oncology clinical trial cohort.
-
Prevalence of low ankle-brachial index, elevated plasma fibrinogen and CRP across Framingham risk categories: data from the National Health and Nutrition Examination Survey (NHANES) 1999-2004.
-
Prevention of ischemically induced neointimal hyperplasia using ex vivo antisense oligodeoxynucleotides.
-
Primate-specific melanoma antigen-A11 regulates isoform-specific human progesterone receptor-B transactivation.
-
Pro-oxidant status and Nrf2 levels in psoriasis vulgaris skin tissues and dimethyl fumarate-treated HaCaT cells.
-
Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target.
-
Progesterone, Inflammatory Cytokine (TNF-α), and Oxidative Stress (H2O2) Regulate Progesterone Receptor Membrane Component 1 Expression in Fetal Membrane Cells.
-
Prognostic and Practical Validation of Current Definitions of Myocardial Infarction Associated With Percutaneous Coronary Intervention.
-
Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial.
-
Progress in therapy for Duchenne muscular dystrophy.
-
Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation.
-
Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors.
-
Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.
-
Protective effects of resveratrol in experimental retinal detachment.
-
Protein expression and functional analysis of the FHIT gene in human tumor cells.
-
Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response.
-
Protein kinase C-zeta is critical in pancreatitis-induced apoptosis of Kupffer cells.
-
Proteomic analysis of proteins related to rice grain chalkiness using iTRAQ and a novel comparison system based on a notched-belly mutant with white-belly.
-
Prothioconazole induces cell cycle arrest by up-regulation of EIF4EBP1 in extravillous trophoblast cells.
-
Prurigo Nodularis Is Characterized by Systemic and Cutaneous T Helper 22 Immune Polarization.
-
Pulmonary expression of iNOS and HO-1 protein is upregulated in a rat model of prehepatic portal hypertension.
-
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma.
-
REST and stress resistance in ageing and Alzheimer's disease.
-
RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence.
-
RNA Pol II accumulates at promoters of growth genes during developmental arrest.
-
Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.
-
Redox-mediated upregulation of hepatocyte iNOS transcription requires coactivator PC4.
-
Regulation of Kupffer cell TNF gene expression during experimental acute pancreatitis: the role of p38-MAPK, ERK1/2, SAPK/JNK, and NF-kappaB.
-
Regulation of Kv1 subunit expression in oligodendrocyte progenitor cells and their role in G1/S phase progression of the cell cycle.
-
Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression.
-
Regulation of human interleukin-8 receptor A: identification of a phosphorylation site involved in modulating receptor functions.
-
Regulation of mitochondrial biogenesis in skeletal muscle by CaMK.
-
Regulation of myeloid leukaemia by the cell-fate determinant Musashi.
-
Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin.
-
Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma.
-
Relationship Between Peak Troponin Values and Long-Term Ischemic Events Among Medically Managed Patients With Acute Coronary Syndromes.
-
Relationship between lifetime ovulatory cycles and overexpression of mutant p53 in epithelial ovarian cancer.
-
Release of endogenous danger signals from HIFU-treated tumor cells and their stimulatory effects on APCs.
-
Renin-angiotensin-aldosterone genotype influences ventricular remodeling in infants with single ventricle.
-
Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease.
-
Requirement of the human T-cell leukemia virus (HTLV-1) tax-stimulated HIAP-1 gene for the survival of transformed lymphocytes.
-
Restoration of the cystic fibrosis transmembrane conductance regulator function by splicing modulation.
-
Retinal pigment epithelial cells induce foxp3(+) regulatory T cells via membrane-bound TGF-β.
-
Rising PSA Level in an Anxious Postprostatectomy Patient.
-
Role of JAK3 in CD40-mediated signaling.
-
Role of alternative oxidase gene in pathogenesis of Cryptococcus neoformans.
-
Role of cyclin D1 as a mediator of c-Met- and beta-catenin-induced hepatocarcinogenesis.
-
Role of hyaluronan and hyaluronan-binding proteins in human asthma.
-
Role of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growth.
-
Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype.
-
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
-
SOCS3 inhibiting migration of A549 cells correlates with PYK2 signaling in vitro.
-
STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers.
-
STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation.
-
SYT-SSX1 (synovial sarcoma translocated) regulates PIASy ligase activity to cause overexpression of NCOA3 protein.
-
Scarecrow-like 3 promotes gibberellin signaling by antagonizing master growth repressor DELLA in Arabidopsis.
-
Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair.
-
Secretion of MIP-1β and MIP-1α by CD8(+) T-lymphocytes correlates with HIV-1 inhibition independent of coreceptor usage.
-
Segment-specific association between plasma homocysteine level and carotid artery intima-media thickness in the Framingham Offspring Study.
-
Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis.
-
Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons.
-
Selective upregulated expression of the alpha2-macroglobulin signaling receptor in highly metastatic 1-LN prostate carcinoma cells.
-
Semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells.
-
Serum C-reactive protein level and prehypertension in two Asian populations.
-
Serum Troponin Level in Acute Ischemic Stroke Identifies Patients with Visceral Infarcts.
-
Severe tuberculosis induces unbalanced up-regulation of gene networks and overexpression of IL-22, MIP-1alpha, CCL27, IP-10, CCR4, CCR5, CXCR3, PD1, PDL2, IL-3, IFN-beta, TIM1, and TLR2 but low antigen-specific cellular responses.
-
Sex Differential in 15-Hydroxyprostaglandin Dehydrogenase Levels in the Lumen of Human Intracranial Aneurysms.
-
ShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis.
-
Short small-interfering RNAs produce interferon-α-mediated analgesia.
-
Simultaneous proteomic profiling of four different growth states of human fibroblasts, using amine-reactive isobaric tagging reagents and tandem mass spectrometry.
-
Simvastatin increases endothelial nitric oxide synthase and ameliorates cerebral vasospasm resulting from subarachnoid hemorrhage.
-
Simvastatin treatment improves functional recovery after experimental spinal cord injury by upregulating the expression of BDNF and GDNF.
-
Single cell RNA-seq reveals profound transcriptional similarity between Barrett's oesophagus and oesophageal submucosal glands.
-
Single-molecule analysis of myocyte differentiation reveals bimodal lineage commitment.
-
Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction.
-
Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo.
-
Soluble alpha2-macroglobulin receptor is increased in endotracheal aspirates from infants and children after cardiopulmonary bypass.
-
Soluble miniagrin enhances contractile function of engineered skeletal muscle.
-
Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent.
-
Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.
-
Stanniocalcin-1 is a Modifier of Oxygen-Induced Retinopathy Severity.
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Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism.
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Stimulation of GCMa transcriptional activity by cyclic AMP/protein kinase A signaling is attributed to CBP-mediated acetylation of GCMa.
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Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model.
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Superfibronectin, a multimeric form of fibronectin, increases HIV infection of primary CD4+ T lymphocytes.
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Surgery upregulates high mobility group box-1 and disrupts the blood-brain barrier causing cognitive dysfunction in aged rats.
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Survival of retinal pigment epithelium after exposure to prolonged oxidative injury: a detailed gene expression and cellular analysis.
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Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis.
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Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior.
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Syndecan-1 expression is up-regulated in pancreatic but not in other gastrointestinal cancers.
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Syndecan-1 facilitates breast cancer metastasis to the brain.
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Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis.
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Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers.
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T cell activation up-regulates the expression of the focal adhesion kinase Pyk2: opposing roles for the activation of protein kinase C and the increase in intracellular Ca2+.
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T-cell receptor α enhancer is inactivated in αβ T lymphocytes.
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TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination.
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TLR agonists regulate PDGF-B production and cell proliferation through TGF-beta/type I IFN crosstalk.
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TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling.
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TRPV4 Moves toward Center-Fold in Rosacea Pathogenesis.
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Targeted activation of c-Jun N-terminal kinase in vivo induces restrictive cardiomyopathy and conduction defects.
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Targeted inhibition of calcineurin in pressure-overload cardiac hypertrophy. Preservation of systolic function.
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Targeting RET Kinase in Neuroendocrine Prostate Cancer.
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Targeting UDP-α-D-glucose 6-dehydrogenase inhibits glioblastoma growth and migration.
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Tau deficiency leads to the upregulation of BAF-57, a protein involved in neuron-specific gene repression.
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Temporal spatial expression and function of non-muscle myosin II isoforms IIA and IIB in scar remodeling.
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Tenascin-C, over expressed in lung cancer down regulates effector functions of tumor infiltrating lymphocytes.
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Testosterone supplementation upregulates androgen receptor expression and translational capacity during severe energy deficit.
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The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis.
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The Alzheimer's associated 5' region of the SORL1 gene cis regulates SORL1 transcripts expression.
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The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.
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The Dynamic and Transient Immune Microenvironment in Locally Advanced Esophageal Adenocarcinoma Post Chemoradiation.
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The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells.
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The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis.
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The MicroRNA miR-191 Supports T Cell Survival Following Common γ Chain Signaling.
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The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming.
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The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer.
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The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages.
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The aorta wall of patients presenting to the emergency department with acute myocardial infarction by cardiac magnetic resonance.
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The c-Abl tyrosine kinase is regulated downstream of the B cell antigen receptor and interacts with CD19.
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The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages.
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The chromatin-binding protein Smyd1 restricts adult mammalian heart growth.
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The clinical utility of immunoglobulin G4 in the evaluation of autoimmune pancreatitis and pancreatic adenocarcinoma.
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The conformation-dependent interaction of alpha 2-macroglobulin with vascular endothelial growth factor. A novel mechanism of alpha 2-macroglobulin/growth factor binding.
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The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis.
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The influence of various patient characteristics on D-dimer concentration in critically ill patients and its role as a prognostic indicator in the intensive care unit setting.
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The interleukin-2 receptor α chain (CD25) plays an important role in regulating monocyte-derived CD40 expression during anti-porcine cellular responses.
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The monomeric receptor binding domain of tetrameric α2-macroglobulin binds to cell surface GRP78 triggering equivalent activation of signaling cascades.
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The multifunctional Ca²⁺/calmodulin-dependent kinase IIδ (CaMKIIδ) regulates arteriogenesis in a mouse model of flow-mediated remodeling.
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The pulling, pushing and fusing of lens fibers: a role for Rho GTPases.
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The release of microparticles by apoptotic cells and their effects on macrophages.
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The role of alterations in mitochondrial dynamics and PGC-1α over-expression in fast muscle atrophy following hindlimb unloading.
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The role of membrane lipids in the induction of macrophage apoptosis by microparticles.
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The role of p65 NF-kappaB/RelA in pancreatitis-induced Kupffer cell apoptosis.
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The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response.
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The transcription factor Twist1 in the distal nephron but not in macrophages propagates aristolochic acid nephropathy.
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The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.
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The utrophin A 5'-untranslated region confers internal ribosome entry site-mediated translational control during regeneration of skeletal muscle fibers.
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Therapeutic Benefit of Autophagy Modulation in Pompe Disease.
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Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states.
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Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.
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Thymic microenvironment induces HIV expression. Physiologic secretion of IL-6 by thymic epithelial cells up-regulates virus expression in chronically infected cells.
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Thymic model for examining BRCA2 expression and function.
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Time course of LPS-induced gene expression in a mouse model of genitourinary inflammation.
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Tissue-engineered cartilage with inducible and tunable immunomodulatory properties.
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Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.
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Toll-like receptor 2-dependent and -independent activation of macrophages by group B streptococci.
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Transcription factor TFII-I causes transcriptional upregulation of GRP78 synthesis in prostate cancer cells.
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Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways.
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Transcriptional regulation of Bim by FOXO3a and Akt mediates scleroderma serum-induced apoptosis in endothelial progenitor cells.
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Transcriptional regulation of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa: dissection of key promoter elements.
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Transcriptional regulation of matrix gla protein.
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Transcriptional response to hypoxia in human tumors.
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Transdifferentiation of human endothelial progenitors into smooth muscle cells.
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Transforming growth factor beta3 regulates the versican variants in the extracellular matrix-rich uterine leiomyomas.
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Transglutaminase 2 protects against ischemic stroke.
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Transiently overexpressed alpha2-adrenoceptors and their control of DNA synthesis in the developing brain.
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Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression.
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Tumor Suppressors RB1 and CDKN2a Cooperatively Regulate Cell-Cycle Progression and Differentiation During Cardiomyocyte Development and Repair.
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Tumor cells upregulate normoxic HIF-1α in response to doxorubicin.
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Type I interferon pathway in adult and juvenile dermatomyositis.
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Tyrosine kinase ETK/BMX is up-regulated in bladder cancer and predicts poor prognosis in patients with cystectomy.
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Ultraviolet light exposure suppresses contact hypersensitivity by abrogating endothelial intercellular adhesion molecule-1 up-regulation at the elicitation site.
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Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia.
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Up-Regulation of PARP1 Expression Significantly Correlated with Poor Survival in Mucosal Melanomas.
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Up-regulated P21CIP1 expression is part of the regulation quantitatively controlling serum deprivation-induced apoptosis.
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Up-regulated cytotrophoblast DOCK4 contributes to over-invasion in placenta accreta spectrum.
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Up-regulated expression of extracellular matrix remodeling genes in phagocytically challenged trabecular meshwork cells.
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Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells.
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Up-regulation of GRP78 and antiapoptotic signaling in murine peritoneal macrophages exposed to insulin.
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Up-regulation of Hedgehog pathway is associated with cellular permissiveness for hepatitis C virus replication.
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Up-regulation of SNCA gene expression: implications to synucleinopathies.
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Up-regulation of connexin45 in heart failure.
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Up-regulation of cyclooxygenase-2 expression and prostaglandin synthesis in endometrial stromal cells by malignant endometrial epithelial cells. A paracrine effect mediated by prostaglandin E2 and nuclear factor-kappa B.
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Up-regulation of hypoxia-inducible factor 1 alpha and hemodynamic responses following massive small bowel resection.
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Up-regulation of nicotinic acetylcholine receptors in menthol cigarette smokers.
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Up-regulation of proline-rich tyrosine kinase 2 in non-small cell lung cancer.
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Up-regulation of the alpha2-macroglobulin signaling receptor on rheumatoid synovial fibroblasts.
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Up-regulation of tissue factor in human pulmonary artery endothelial cells after ultrafine particle exposure.
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Up-regulation of tumor susceptibility gene 101 conveys poor prognosis through suppression of p21 expression in ovarian cancer.
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Update on fibroblast growth factor 23 in chronic kidney disease.
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Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner.
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Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study.
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Upregulation of AKT1 protein expression in forskolin-stimulated macrophage: evidence from ChIP analysis that CREB binds to and activates the AKT1 promoter.
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Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice.
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Upregulation of IL-1β, IL-6, and CCL-2 by a novel mouse model of pancreatic ischemia-reperfusion injury.
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Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.
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Upregulation of cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) in wall of ruptured human cerebral aneurysms: preliminary results.
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Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis.
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Upregulation of forces and morphogenic asymmetries in dorsal closure during Drosophila development.
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Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.
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Upregulation of macrophage plasma membrane and nuclear phospholipase D activity on ligation of the alpha2-macroglobulin signaling receptor: involvement of heterotrimeric and monomeric G proteins.
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Upregulation of osmo-mechanosensitive TRPV4 channel facilitates chronic hypoxia-induced myogenic tone and pulmonary hypertension.
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Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats.
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Upregulation of the voltage-gated sodium channel beta2 subunit in neuropathic pain models: characterization of expression in injured and non-injured primary sensory neurons.
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Use of gene expression profiling to direct in vivo molecular imaging of lung cancer.
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Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants.
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Vascular endothelial growth factor up-regulates cyclooxygenase-2 expression in human endothelial cells.
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Venous thromboembolism, interleukin-6 and survival outcomes in patients with advanced ovarian clear cell carcinoma.
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WIPI1 is a conserved mediator of right ventricular failure.
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Whole blood gene expression analyses in patients with single versus recurrent venous thromboembolism.
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Wnt proteins synergize to activate β-catenin signaling.
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Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27.
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ZAP-70 tyrosine kinase is required for the up-regulation of Fas ligand in activation-induced T cell apoptosis.
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c-FLIP protects eosinophils from TNF-α-mediated cell death in vivo.
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c-Jun promotes whereas JunB inhibits epidermal neoplasia.
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cDNA array of lipopolysaccharide-induced bladder gene expression.
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eIF4E-phosphorylation-mediated Sox2 upregulation promotes pancreatic tumor cell repopulation after irradiation.
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hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.
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lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.
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p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia.
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Keywords of People
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Bennett, Vann,
George Barth Geller Distinguished Professor of Molecular Biology,
Duke Cancer Institute
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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Bradford, Daniel William,
Professor of Psychiatry and Behavioral Sciences,
Psychiatry, Child & Family Mental Health & Community Psychiatry
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Buckley, Rebecca Hatcher,
Professor Emeritus of Pediatrics,
Pediatrics, Allergy and Immunology
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Choi, Steven Sok,
Associate Professor of Medicine,
Medicine, Gastroenterology
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Gunn, Michael Dee,
Professor of Medicine,
Immunology
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Hirschey, Matthew,
Associate Professor of Medicine,
Cell Biology
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Laskowitz, Daniel Todd,
Professor of Neurology,
Duke Science & Society
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Luftig, Micah Alan,
Associate Professor of Molecular Genetics and Microbiology,
Cell Biology
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McDonnell, Donald Patrick,
Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine,
Cell Biology
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Milano, Carmelo Alessio,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Surgery, Cardiovascular and Thoracic Surgery
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Yan, Hai,
Adjunct Professor of Pathology,
Pathology