Estrogen Replacement Therapy

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  Subject Areas on Research

  • A path model of chronic stress, the metabolic syndrome, and coronary heart disease. 
  • A randomized pilot trial of estrogen replacement therapy in post-menopausal women with Parkinson's disease. 
  • A situation-specific theory of Asian immigrant women's menopausal symptom experience in the United States. 
  • A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer. 
  • Active lifestyle offsets HRT-induced suppression of T cell reactivity to mitogens. 
  • Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk. 
  • Associations among personal care product use patterns and exogenous hormone use in the NIEHS Sister Study. 
  • Benefits and drawbacks to hormone replacement therapy among nursing home patients. 
  • Blood pressure control and hormone replacement therapy in postmenopausal women at risk for coronary heart disease. 
  • Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II). 
  • Clinical management of primary hyperparathyroidism and thresholds for surgical referral: a national study examining concordance between practice patterns and consensus panel recommendations. 
  • Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein. 
  • DNA repair and epidemiology of basal cell carcinoma. 
  • DNA repair related to multiple skin cancers and drug use. 
  • Depressive symptoms, menopausal status, and climacteric symptoms in women at midlife. 
  • Differences in brain volumes among males and female hormone-therapy users and nonusers. 
  • Differences in providers' beliefs about benefits and risks of hormone replacement therapy in managed care. 
  • Differences in the estrogen content of breast adipose tissue in women by menopausal status and hormone use. 
  • Do older women use estrogen replacement? Data from the Duke Established Populations for Epidemiologic Studies of the Elderly (EPESE) 
  • Effect of blood tamoxifen concentrations on surrogate biomarkers in a trial of dose reduction in healthy women. 
  • Effect of estrogen replacement therapy on corrected thrombolysis in myocardial infarction frame count. 
  • Effect of tamoxifen and transdermal hormone replacement therapy on cardiovascular risk factors in a prevention trial. Italian Chemoprevention Group. 
  • Effects of Calcium, Vitamin D, and Hormone Therapy on Cardiovascular Disease Risk Factors in the Women's Health Initiative: A Randomized Controlled Trial. 
  • Efficacy and tolerability of lovastatin in 3390 women with moderate hypercholesterolemia. 
  • Endometrial hyperplasia risk in relation to recent use of oral contraceptives and hormone therapy. 
  • Enhanced cognitive performance with estrogen use in nondemented community-dwelling older women. 
  • Estrogen effects on cognition across the lifespan. 
  • Estrogen replacement therapy and retinal vascular caliber. 
  • Estrogen, estrogen plus progestin therapy, and risk of breast cancer. 
  • Evaluating participants' use of a hormone replacement therapy decision-making intervention. 
  • Evidence supporting secondary prevention strategies. 
  • Exogenous hormone use and meningioma risk: what do we tell our patients? 
  • Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females. 
  • Focusing on inflammation in the treatment of atherosclerosis. 
  • For patients: hormone replacement therapy. 
  • Fracture Rates and Bone Density Among Postmenopausal Veteran and Non-Veteran Women From the Women's Health Initiative. 
  • Gender and heart disease. 
  • Gender and menopause impact severity of fibrosis among patients with nonalcoholic steatohepatitis. 
  • Guidelines for carotid endarterectomy: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. 
  • HRT & the World Wide Web. Helping patients find good information on the web. 
  • Hormone replacement improves hemodynamic profile and left ventricular geometry in hypertensive and normotensive postmenopausal women. 
  • Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study. 
  • Hormone replacement therapy and ischemic stroke severity in women: a case-control study. 
  • Hormone replacement therapy and the risk of death from breast cancer: a systematic review. 
  • Hormone replacement therapy menopause with a better future--a survey of views on hormone replacement therapy (HRT). 
  • Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study. 
  • Hormone therapy does not affect depression severity in older women. 
  • Hormone therapy for the management of menopausal symptoms: pharmacotherapy update. 
  • Hormone therapy: physiological complexity belies therapeutic simplicity. 
  • Impact of estrogen use on decline in cognitive function in a representative sample of older community-resident women. 
  • Impact of hormone replacement therapy on exercise training-induced improvements in insulin action in sedentary overweight adults. 
  • Implanted estrogen pellets associated with hypertriglyceridemia, biliary dyskinesia and focal nodular hyperplasia of the liver: a case report. 
  • Increased blood pressure in mice lacking cytochrome P450 2J5. 
  • Initiation and discontinuation of hormone therapy for menopausal symptoms: results from a community sample. 
  • Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up. 
  • Inverse association of female hormone replacement therapy with age-related macular degeneration and interactions with ARMS2 polymorphisms. 
  • Italian randomized trial among women with hysterectomy: tamoxifen and hormone-dependent breast cancer in high-risk women. 
  • Menopausal hormones and risk of ovarian cancer. 
  • Menopause and mood. Is depression linked with hormone changes? 
  • Menostar - a low-dose estrogen patch for osteoporosis. 
  • Mesh erosion in abdominal sacral colpopexy with and without concomitant hysterectomy. 
  • Mining the complexities of the estrogen signaling pathways for novel therapeutics. 
  • Modification of the effects of estrogen therapy on HDL cholesterol levels by polymorphisms of the HDL-C receptor, SR-BI: the Rancho Bernardo Study. 
  • Monitoring the randomized trials of the Women's Health Initiative: the experience of the Data and Safety Monitoring Board. 
  • Perceptions of menopausal stage and patterns of hormone replacement therapy use. 
  • Postmenopausal hormone replacement therapy. Information for effective patient counseling. 
  • Postmenopausal hormone use in women with acute coronary syndromes. 
  • Postmenopausal oral estrogen therapy and blood pressure in normotensive and hypertensive subjects: the Estrogen in the Prevention of Atherosclerosis Trial. 
  • Premenopausal Hysterectomy and Risk of Ovarian Cancer in African-American Women. 
  • Prevention and health services delivery. 
  • Prevention of breast cancer with tamoxifen: preliminary findings from the Italian randomised trial among hysterectomised women. Italian Tamoxifen Prevention Study. 
  • Primary prevention of stroke. 
  • Race, Menopausal Hormone Therapy, and Invasive Breast Cancer in the Carolina Breast Cancer Study. 
  • Racial differences in tumor grade among women with endometrial cancer. 
  • Relation between estrogen replacement therapy and restenosis after percutaneous coronary interventions. 
  • Risk factors for breast cancer characterized by the estrogen receptor alpha A908G (K303R) mutation. 
  • Selective estrogen receptor modulators (SERMs): A first step in the development of perfect hormone replacement therapy regimen. 
  • Smoking cessation in peri- and postmenopausal women: a review. 
  • Statin use and stroke outcomes in the Heart and Estrogen-Progestin Replacement Study (HERS). 
  • Surgical Menopause and Frailty Risk in Community-Dwelling Older Women: Study of Osteoporotic Fractures. 
  • The cardiovascular patient's perceptions of complementary and alternative medicine. 
  • The ethics of aggregation and hormone replacement therapy. 
  • The nonhuman primate model of the relationship between gonadal steroids and coronary heart disease. 
  • The role of menopausal hormone therapy in preventing osteoporotic fractures: a critical review of the clinical evidence. 
  • Transdermal progesterone cream as an alternative progestin in hormone therapy. 
  • Transdermal versus oral estrogen therapy in postmenopausal smokers: hemodynamic and endothelial effects. 
  • Treatment of menorrhagia in women undergoing hematopoietic stem cell transplantation. 
  • Type and duration of exogenous hormone use affects breast cancer histology. 
  • Unopposed estradiol therapy in postmenopausal women: results from two randomized trials. 
  • Update on Alzheimer's disease. Promising advances in detection and treatment. 
  • Using conjoint analysis to estimate healthy-year equivalents for acute conditions: an application to vasomotor symptoms. 
  • Why cardiologists should be interested in estrogen. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Duke Innovation & Entrepreneurship
  • Moorman, Patricia Gripka, Professor in Family Medicine and Community Health, Duke Cancer Institute
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology