Gene Expression Regulation, Bacterial
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Subject Areas on Research
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A 'Semi-Protected Oligonucleotide Recombination' Assay for DNA Mismatch Repair in vivo Suggests Different Modes of Repair for Lagging Strand Mismatches.
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A Bacterial Chromosome Structuring Protein Binds Overtwisted DNA to Stimulate Type II Topoisomerases and Enable DNA Replication.
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A Bayesian network approach to operon prediction.
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A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
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A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection.
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A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon.
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A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus.
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A eukaryote-like cardiolipin synthase is present in Streptomyces coelicolor and in most actinobacteria.
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A hairpin near the 5' end stabilises the DNA gyrase mRNA in Mycobacterium smegmatis.
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A noisy linear map underlies oscillations in cell size and gene expression in bacteria.
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A novel relaxase homologue is involved in chromosomal DNA processing for type IV secretion in Neisseria gonorrhoeae.
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A regulatory hierarchy controls the dynamic transcriptional response to extreme oxidative stress in archaea.
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A strong effect of AT mutational bias on amino acid usage in Buchnera is mitigated at high-expression genes.
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A whole more than the sum of its synthetic parts.
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Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy.
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An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation.
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Avicinylation (thioesterification): a protein modification that can regulate the response to oxidative and nitrosative stress.
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Axial distortion as a sensor of supercoil changes: a molecular model for the homeostatic regulation of DNA gyrase.
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Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction.
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Bioelectronic measurement and feedback control of molecules in living cells.
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Broad-host-range vectors for protein expression across gram negative hosts.
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Calcium binding properties of the Kingella kingae PilC1 and PilC2 proteins have differential effects on type IV pilus-mediated adherence and twitching motility.
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Characterization and structure of the manganese-responsive transcriptional regulator ScaR.
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Characterization of the SarA virulence gene regulator of Staphylococcus aureus.
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Chromosomal expression of the Haemophilus influenzae Hap autotransporter allows fine-tuned regulation of adhesive potential via inhibition of intermolecular autoproteolysis.
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Comparative transcriptome analysis of the CO2 sensing pathway via differential expression of carbonic anhydrase in Cryptococcus neoformans.
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Computational design of a Zn2+ receptor that controls bacterial gene expression.
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Conformational plasticity of the coiled-coil domain of BmrR is required for bmr operator binding: the structure of unliganded BmrR.
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Coupling spatial segregation with synthetic circuits to control bacterial survival.
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Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the alpha C-terminal domain of RNA polymerase.
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Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus.
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DNA damage responses in prokaryotes: regulating gene expression, modulating growth patterns, and manipulating replication forks.
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DNA mismatch repair: functions and mechanisms.
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Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR.
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Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system.
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Diet rapidly and reproducibly alters the human gut microbiome.
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Discrimination of tRNALeu isoacceptors by the insertion mutant of Escherichia coli leucyl-tRNA synthetase.
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Dissecting the in vivo metabolic potential of two human gut acetogens.
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Dissection of the molecular circuitry controlling virulence in Francisella tularensis.
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DsbB is required for the pathogenesis process of Xanthomonas campestris pv. campestris.
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Effect of carbon source addition on toluene biodegradation by an Escherichia coli DH5alpha transconjugant harboring the TOL plasmid.
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Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition.
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Employing Rhodobacter sphaeroides to functionally express and purify human G protein-coupled receptors.
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Engineering key components in a synthetic eukaryotic signal transduction pathway.
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Epigenetic regulation of the nitrosative stress response and intracellular macrophage survival by extraintestinal pathogenic Escherichia coli.
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Escherichia coli, but not Staphylococcus aureus triggers an early increased expression of factors contributing to the innate immune defense in the udder of the cow.
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Examination of type IV pilus expression and pilus-associated phenotypes in Kingella kingae clinical isolates.
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Examining relationships between total silver concentration and Sil silver resistance genes in domestic wastewater treatment plants.
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Expression of Kingella kingae type IV pili is regulated by sigma54, PilS, and PilR.
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Expression of penicillin G acylase from the cloned pac gene of Escherichia coli ATCC11105. Effects of pacR and temperature.
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Filamentation by Escherichia coli subverts innate defenses during urinary tract infection.
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Flavin-dependent thymidylate synthase ThyX activity: implications for the folate cycle in bacteria.
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Fluorescence-based isolation of bacterial genes expressed within host cells.
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Functional consequences of substitution mutations in MepR, a repressor of the Staphylococcus aureus MepA multidrug efflux pump gene.
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Gene expression level influences amino acid usage, but not codon usage, in the tsetse fly endosymbiont Wigglesworthia.
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Gene expression levels influence amino acid usage and evolutionary rates in endosymbiotic bacteria.
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Genetic analysis of the requirements for SOS induction by nalidixic acid in Escherichia coli.
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Genetic and Molecular Basis of Kingella kingae Encapsulation.
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Genetic heterogeneity in MCAD deficiency: frequency of K329E allele and identification of three additional mutant alleles.
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Global gene expression of Prochlorococcus ecotypes in response to changes in nitrogen availability.
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Glutathione activates virulence gene expression of an intracellular pathogen.
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High-level expression of Escherichia coli NADPH-sulfite reductase: requirement for a cloned cysG plasmid to overcome limiting siroheme cofactor.
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HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
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HspR is a global negative regulator of heat shock gene expression in Deinococcus radiodurans.
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Identification of a regulated alkaline phosphatase, a cell surface-associated lipoprotein, in Mycobacterium smegmatis.
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Identification of host-induced pathogen genes by differential fluorescence induction reporter systems.
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Identification of unusual Chlamydia pecorum genotypes in Victorian koalas (Phascolarctos cinereus) and clinical variables associated with infection.
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Impacts of silver nanoparticle coating on the nitrification potential of Nitrosomonas europaea.
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In vitro interactions of CysB protein with the cysK and cysJIH promoter regions of Salmonella typhimurium.
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Involvement of two putative alternative sigma factors in stress response of the radioresistant bacterium Deinococcus radiodurans.
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Kingella kingae expresses type IV pili that mediate adherence to respiratory epithelial and synovial cells.
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Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles.
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LeuX tRNA-dependent and -independent mechanisms of Escherichia coli pathogenesis in acute cystitis.
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LexA protein of Escherichia coli represses expression of the Tn5 transposase gene.
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Low-shear modeled microgravity: a global environmental regulatory signal affecting bacterial gene expression, physiology, and pathogenesis.
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Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival.
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Mating pair formation homologue TraG is a variable membrane protein essential for contact-independent type IV secretion of chromosomal DNA by Neisseria gonorrhoeae.
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Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus.
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Methylthioadenosine Suppresses Salmonella Virulence.
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Microarray analysis identifies Salmonella genes belonging to the low-shear modeled microgravity regulon.
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Modelling regulatory pathways in E. coli from time series expression profiles.
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Molecular basis of ChvE function in sugar binding, sugar utilization, and virulence in Agrobacterium tumefaciens.
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Molecular microbiology: new dimensions for cutaneous biology and wound healing.
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Multifunctional analysis of Chlamydia-specific genes in a yeast expression system.
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Mutations within the mepA operator affect binding of the MepR regulatory protein and its induction by MepA substrates in Staphylococcus aureus.
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Niche-specific contribution to streptococcal virulence of a MalR-regulated carbohydrate binding protein.
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Nitrosative stress: activation of the transcription factor OxyR.
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NlpI-mediated modulation of outer membrane vesicle production through peptidoglycan dynamics in Escherichia coli.
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Noise reduction by diffusional dissipation in a minimal quorum sensing motif.
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Optimal tuning of bacterial sensing potential.
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Oscillations by minimal bacterial suicide circuits reveal hidden facets of host-circuit physiology.
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Perturbation of Staphylococcus aureus gene expression by the enoyl-acyl carrier protein reductase inhibitor AFN-1252.
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Photosynthesis genes in marine viruses yield proteins during host infection.
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Probing for Binding Regions of the FtsZ Protein Surface through Site-Directed Insertions: Discovery of Fully Functional FtsZ-Fluorescent Proteins.
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Prochlorococcus: approved for export.
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Programmed population control by cell-cell communication and regulated killing.
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Prokaryotic transcription regulators: more than just the helix-turn-helix motif.
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Protection from nitrosative stress: a central role for microbial flavohemoglobin.
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Purification and mutagenesis of LpxL, the lauroyltransferase of Escherichia coli lipid A biosynthesis.
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Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms.
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Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa.
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Recognition of U-rich RNA by Hfq from the Gram-positive pathogen Listeria monocytogenes.
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Recombinant Rhodobacter capsulatus xanthine dehydrogenase, a useful model system for the characterization of protein variants leading to xanthinuria I in humans.
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Regulation of DNA gyrase operon in Mycobacterium smegmatis: a distinct mechanism of relaxation stimulated transcription.
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Regulation of carbon utilization by sulfur availability in Escherichia coli and Salmonella typhimurium.
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Regulation of iron transport related genes by boron in the marine bacterium Marinobacter algicola DG893.
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Relationships between protein-encoding gene abundance and corresponding process are commonly assumed yet rarely observed.
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Residue threonine-149 of the Salmonella typhimurium CysB transcription activator: mutations causing constitutive expression of positively regulated genes of the cysteine regulon.
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Reversal of P-glycoprotein expressed in Escherichia coli leaky mutant by ascorbic acid.
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Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis.
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RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa.
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SOS induction as an in vivo assay of enzyme-DNA interactions.
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Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines.
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Selection of strains for quality assessment of the disk induction method for detection of inducible clindamycin resistance in Staphylococci: a CLSI collaborative study.
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Sinorhizobium meliloti phospholipase C required for lipid remodeling during phosphorus limitation.
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Stress-induced outer membrane vesicle production by Pseudomonas aeruginosa.
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Structural and Functional Analyses Reveal Insights into the Molecular Properties of the Escherichia coli Z Ring Stabilizing Protein, ZapC.
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Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA.
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Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR.
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Structural basis for the metal-selective activation of the manganese transport regulator of Bacillus subtilis.
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Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR.
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Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR.
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Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
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Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis.
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Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
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Structures of the activator of K. pneumonia biofilm formation, MrkH, indicates PilZ domains involved in c-di-GMP and DNA binding.
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Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein.
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Synthetic biology: Division of logic labour.
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Temporal control of self-organized pattern formation without morphogen gradients in bacteria.
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The Haemophilus influenzae Hap autotransporter mediates microcolony formation and adherence to epithelial cells and extracellular matrix via binding regions in the C-terminal end of the passenger domain.
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The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development.
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The crystal structure of the RsbN-σBldN complex from Streptomyces venezuelae defines a new structural class of anti-σ factor.
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The cysP promoter of Salmonella typhimurium: characterization of two binding sites for CysB protein, studies of in vivo transcription initiation, and demonstration of the anti-inducer effects of thiosulfate.
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The effect of osmotic stress on the production of nukacin ISK-1 from Staphylococcus warneri ISK-1.
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The lipid lysyl-phosphatidylglycerol is present in membranes of Rhizobium tropici CIAT899 and confers increased resistance to polymyxin B under acidic growth conditions.
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The molecular basis for positive regulation of cys promoters in Salmonella typhimurium and Escherichia coli.
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The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus.
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The ompU Paralogue vca1008 is required for virulence of Vibrio cholerae.
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The staphylococcal QacR multidrug regulator binds a correctly spaced operator as a pair of dimers.
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The vibrio cholerae hybrid sensor kinase VieS contributes to motility and biofilm regulation by altering the cyclic diguanylate level.
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Tn5-mediated bleomycin resistance in Escherichia coli requires the expression of host genes.
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Transcription-associated mutation of lasR in Pseudomonas aeruginosa.
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Tuberculosis genes expressed during persistence and reactivation in the resistant rabbit model.
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Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization.
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[Synthesis of human proinsulin in Escherichia coli cells]
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cPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatis.
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