Gene Expression Regulation, Viral

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  Subject Areas on Research

  • A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys. 
  • A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation. 
  • A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation. 
  • A two-phase innate host response to alphavirus infection identified by mRNP-tagging in vivo. 
  • Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability. 
  • Activity of a type 1 picornavirus internal ribosomal entry site is determined by sequences within the 3' nontranslated region. 
  • Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells. 
  • Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. 
  • An RNA tertiary switch by modifying how helices are tethered. 
  • An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface. 
  • Antisense inhibitors, ribozymes, and siRNAs. 
  • Antitermination by bacteriophage lambda Q protein. 
  • Assessment of antibody responses against gp41 in HIV-1-infected patients using soluble gp41 fusion proteins and peptides derived from M group consensus envelope. 
  • Attenuation of herpes simplex virus neurovirulence with picornavirus cis-acting genetic elements. 
  • CAF-mediated human immunodeficiency virus (HIV) type 1 transcriptional inhibition is distinct from alpha-defensin-1 HIV inhibition. 
  • CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression. 
  • Cell-type-specific repression of internal ribosome entry site activity by double-stranded RNA-binding protein 76. 
  • Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein. 
  • Comprehensive Characterization of the Transmitted/Founder env Genes From a Single MSM Cohort in China. 
  • Contribution of 3CD Region to the Virulence of Enterovirus 71. 
  • Cyclophilin B escorts the hepatitis C virus RNA polymerase: a viral achilles heel? 
  • DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifs. 
  • Defining the spatial relationship between hepatitis C virus infection and interferon-stimulated gene induction in the human liver. 
  • Dengue Virus Targets Nrf2 for NS2B3-Mediated Degradation Leading to Enhanced Oxidative Stress and Viral Replication. 
  • Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3). 
  • Distinctive variation in the U3R region of the 5' Long Terminal Repeat from diverse HIV-1 strains. 
  • Durhamycin A, a potent inhibitor of HIV Tat transactivation. 
  • Dynamic Epstein-Barr virus gene expression on the path to B-cell transformation. 
  • Effects of liver growth factors on hepadnavirus replication in chronically infected duck hepatocytes. 
  • Emergent bistability by a growth-modulating positive feedback circuit. 
  • Enhanced duck hepatitis B virus gene expression following aflatoxin B1 exposure. 
  • Enhanced transduction and improved photoreceptor survival of retinal degeneration by the combinatorial use of rAAV2 with a lower dose of adenovirus. 
  • Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene Expression. 
  • Epstein-Barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency. 
  • Expression and function of the uvsW gene of bacteriophage T4. 
  • Expression of the human poliovirus receptor/CD155 gene during development of the central nervous system: implications for the pathogenesis of poliomyelitis. 
  • HIV-1 Proviral Transcription and Latency in the New Era. 
  • HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. 
  • HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes. 
  • High-level, lasting antiviral immunity induced by a bimodal AIDS vaccine and boosted by live-virus exposure: prevention of viremia. 
  • High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression. 
  • Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements. 
  • Human immunodeficiency virus type 1 Tat activity in human neuronal cells: uptake and trans-activation. 
  • Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter. 
  • IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: the future of personalized HCV therapies. 
  • IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex. 
  • Identification of cis-acting repressor activity within human immunodeficiency virus type 1 protease sequences. 
  • Identification of the orthopoxvirus p4c gene, which encodes a structural protein that directs intracellular mature virus particles into A-type inclusions. 
  • In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms. 
  • Induction of viral, 7-methyl-guanosine cap-independent translation and oncolysis by mitogen-activated protein kinase-interacting kinase-mediated effects on the serine/arginine-rich protein kinase. 
  • Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes. 
  • Interactions between small viral RNAs of vesicular stomatitis virus and components of cellular gene expression. 
  • Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants. 
  • Intrinsic activity of human immunodeficiency virus type 1 protease heterologous fusion proteins in mammalian cells. 
  • Kinetics of cytokine expression during primary human immunodeficiency virus type 1 infection. 
  • La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. 
  • N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. 
  • N6-methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle. 
  • Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression. 
  • Novel function of prothymosin alpha as a potent inhibitor of human immunodeficiency virus type 1 gene expression in primary macrophages. 
  • Patterns of HIV-1 mRNA expression in transgenic mice are tissue-dependent. 
  • Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages. 
  • Photosynthesis genes in marine viruses yield proteins during host infection. 
  • Poliovirus receptor CD155-targeted oncolysis of glioma. 
  • Post-transcription cleavage generates the 3' end of F17R transcripts in vaccinia virus. 
  • Postintegration HIV-1 infection of cervical epithelial cells mediates contact-dependent productive infection of T cells. 
  • Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. 
  • Production of recombinant adeno-associated viral vectors and use for in vitro and in vivo administration. 
  • RNA interference of human papillomavirus type 18 E6 and E7 induces senescence in HeLa cells. 
  • Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections. 
  • Regulation of human retroviral latency by the NF-kappa B/I kappa B family: inhibition of human immunodeficiency virus replication by I kappa B through a Rev-dependent mechanism. 
  • Retroviral gene transduction of circulating progenitor cells in patients with metastatic breast cancer. 
  • Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus. 
  • Review: human endogenous retroviruses and the placenta. 
  • SENP3-mediated host defense response contains HBV replication and restores protein synthesis. 
  • Single-walled carbon nanotubes increase pandemic influenza A H1N1 virus infectivity of lung epithelial cells. 
  • Site-specific RNA cleavage generates the 3' end of a poxvirus late mRNA. 
  • Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53. 
  • The Epstein-Barr virus miR-BHRF1 microRNAs regulate viral gene expression in cis. 
  • The Epstein-Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression. 
  • The ICP0 protein of equine herpesvirus 1 is an early protein that independently transactivates expression of all classes of viral promoters. 
  • The eukaryotic translation initiation factor 4E is not modified during the course of vaccinia virus replication. 
  • The gamma2 late glycoprotein K promoter of equine herpesvirus 1 is differentially regulated by the IE and EICP0 proteins. 
  • The hepatitis C virus 3'-untranslated region or a poly(A) tract promote efficient translation subsequent to the initiation phase. 
  • The polypyrimidine tract binding protein is required for efficient picornavirus gene expression and propagation. 
  • The presence of human papillomavirus-16/-18 E6, p53, and Bcl-2 protein in cervicovaginal smears from patients with invasive cervical cancer. 
  • The products of gene I and the overlapping in-frame gene XI are required for filamentous phage assembly. 
  • The promoter of human T-cell leukemia virus type-I is repressed by the immediate-early gene region of human cytomegalovirus in primary blood lymphocytes. 
  • The role of microRNAs in Epstein-Barr virus latency and lytic reactivation. 
  • Tissue-specific expression from CaMV 35S enhancer subdomains in early stages of plant development. 
  • To be or not IIb: a multi-step process for Epstein-Barr virus latency establishment and consequences for B cell tumorigenesis. 
  • Transcription factor AP-2 regulates human immunodeficiency virus type 1 gene expression. 
  • Transcription of a poxvirus early gene is regulated both by a short promoter element and by a transcriptional termination signal controlling transcriptional interference. 
  • Transcriptional Circuit Fragility Influences HIV Proviral Fate. 
  • Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells. 
  • [Synthesis of human proinsulin in Escherichia coli cells]. 
  • c-Myc Represses Transcription of Epstein-Barr Virus Latent Membrane Protein 1 Early after Primary B Cell Infection. 
  • p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells. 
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  Keywords of People

  • Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology