Least-Squares Analysis

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  Subject Areas on Research

  • A comparison of least squares and conditional maximum likelihood estimators under volume endpoint censoring in tumor growth experiments. 
  • A framework for quality improvement: an analysis of factors responsible for improvement at hospitals participating in the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the ACC/AHA Guidelines (CRUSADE) quality improvement initiative. 
  • A generalized least-squares estimate for the origin of sporophytic self-incompatibility. 
  • A heuristic model of stone comminution in shock wave lithotripsy. 
  • A method for direct localized sound speed estimates using registered virtual detectors. 
  • A modified SPIHT algorithm for image coding with a joint MSE and classification distortion measure. 
  • A two one-sided tests procedure for assessment of individual bioequivalence. 
  • Accurate fatty acid composition estimation of adipose tissue in the abdomen based on bipolar multi-echo MRI. 
  • Acoustic radiation force impulse imaging of mechanical stiffness propagation in myocardial tissue. 
  • Adult physical health outcomes of adolescent girls with conduct disorder, depression, and anxiety. 
  • An Initial Evaluation of the Impact of Pokémon GO on Physical Activity. 
  • An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration. 
  • Antagonistic selection and pleiotropy constrain the evolution of plant chemical defenses. 
  • Anti-AIDS agents 79. Design, synthesis, molecular modeling and structure-activity relationships of novel dicamphanoyl-2',2'-dimethyldihydropyranochromone (DCP) analogs as potent anti-HIV agents. 
  • Application of quantitative coronary angiography in a cineless environment: in vivo assessment of a fully automated system for clinical use. 
  • Arterial windkessel parameter estimation: a new time-domain method. 
  • Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model. 
  • Association Between Bottle Size and Formula Intake in 2-Month-Old Infants. 
  • Assortative mating for antisocial behavior: developmental and methodological implications. 
  • Astragalar morphology of Afradapis, a large adapiform primate from the earliest late Eocene of Egypt. 
  • Automated spectral analysis II: application of wavelet shrinkage for characterization of non-parameterized signals. 
  • Bacteria localization and chorion thinning among preterm premature rupture of membranes. 
  • Behavioral consequences of conflict-oriented health news coverage: the 2009 mammography guideline controversy and online information seeking. 
  • Bias testing, bias correction, and confounder selection using an instrumental variable model. 
  • Building a predictive breast cancer risk model. 
  • Calibrating and validating bacterial water quality models: a Bayesian approach. 
  • Cardiovascular outcomes and the physical and chemical properties of metal ions found in particulate matter air pollution: a QICAR study. 
  • Career progress in online and blended learning environments. 
  • Cigarette smoking and health-related quality of life in Medicare beneficiaries. 
  • Cocaine selectively inhibits beta-adrenergic receptor binding in pregnant human myometrium. 
  • Combining structural and functional measurements to improve detection of glaucoma progression using Bayesian hierarchical models. 
  • Comparison of analytic models for estimating the effect of clinical factors on the cost of coronary artery bypass graft surgery. 
  • Comparison of physiological motion filters for in vivo cardiac ARFI. 
  • Comparison of the efficacy and safety of arformoterol 15 microg twice daily and arformoterol 30 microg once daily in COPD: a single-dose, multicenter, randomized, modified-blind, two-way crossover study. 
  • Compressed sensing with wavelet domain dependencies for coronary MRI: a retrospective study. 
  • Contrast-enhanced MRI and routine single photon emission computed tomography (SPECT) perfusion imaging for detection of subendocardial myocardial infarcts: an imaging study. 
  • Control of the orientational order and nonlinear optical response of the "push-pull" chromophore RuPZn via specific incorporation into densely packed monolayer ensembles of an amphiphilic 4-helix bundle peptide: second harmonic generation at high chromophore densities. 
  • Convergence of neural systems processing stimulus associations and coordinating motor responses. 
  • Convex hull based neuro-retinal optic cup ellipse optimization in glaucoma diagnosis. 
  • Cumulative exposure to CD8+ granzyme Bhi T cells is associated with reduced lung function early after lung transplantation. 
  • Demographic and illness-related variables associated with HIV-related fatigue. 
  • Diabetes mellitus in centenarians. 
  • Diagnosis of breast cancer using diffuse reflectance spectroscopy: Comparison of a Monte Carlo versus partial least squares analysis based feature extraction technique. 
  • Dynamic contrast-enhanced MRI and fractal characteristics of percolation clusters in two-dimensional tumor blood perfusion. 
  • Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial. 
  • Effect of Vericiguat vs Placebo on Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction: The VITALITY-HFpEF Randomized Clinical Trial. 
  • Effect of dialysis center profit-status on patient survival: a comparison of risk-adjustment and instrumental variable approaches. 
  • Effect of electrode surface microstructure on electron transfer induced conformation changes in cytochrome c monitored by in situ UV and CD spectroelectrochemistry. 
  • Effect of race on cultural justifications for caregiving. 
  • Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes. 
  • Effects of dietary phosphate restriction and phosphate binders on FGF23 levels in CKD. 
  • Effects of olanzapine, quetiapine, and risperidone on neurocognitive function in early psychosis: a randomized, double-blind 52-week comparison. 
  • Effects of premature termination codon polymorphisms in the Drosophila pseudoobscura subclade. 
  • Efficacy of guanfacine extended release in the treatment of combined and inattentive only subtypes of attention-deficit/hyperactivity disorder. 
  • Enhanced T2 contrast for MR histology of the mouse brain. 
  • Estimating stimulus response latency. 
  • Estimation of the warfarin dose with clinical and pharmacogenetic data. 
  • Evaluating medical diagnostic tests at the subunit level in the presence of verification bias. 
  • Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease. 
  • Explained and unexplained medical symptoms in generalized anxiety and panic disorder: relationship to the somatoform disorders. 
  • Fine-root respiration in a loblolly pine (Pinus taeda L.) forest exposed to elevated CO2 and N fertilization. 
  • Functional associations of "trouble seeing". 
  • Functional morphology of the hallucal metatarsal with implications for inferring grasping ability in extinct primates. 
  • Glutathione species and metabolomic prints in subjects with liver disease as biological markers for the detection of hepatocellular carcinoma. 
  • Granulocyte-colony stimulating factor use and medical costs after initial adjuvant chemotherapy in older patients with early-stage breast cancer. 
  • Greater depression severity associated with less improvement in depression-associated cognitive deficits in older subjects. 
  • Haemodynamic effects of rolofylline in the treatment of patients with heart failure and impaired renal function. 
  • Healthcare cost differences with participation in a community-based group physical activity benefit for medicare managed care health plan members. 
  • High-sensitivity analysis of buprenorphine, norbuprenorphine, buprenorphine glucuronide, and norbuprenorphine glucuronide in plasma and urine by liquid chromatography-mass spectrometry. 
  • Highly active antiretroviral therapy and the epidemic of HIV+ end-stage renal disease. 
  • Host longevity and parasite species richness in mammals. 
  • Identification of an urinary metabolite profile associated with osteoarthritis. 
  • Insurance mandates and trends in infertility treatments. 
  • Interlocking trajectories of loss-related events and depressive symptoms among elders. 
  • Intramyocardial, autologous CD34+ cell therapy for refractory angina. 
  • Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder. 
  • Investigating the relationship between surface chemistry and endothelial cell growth: partial least-squares regression of the static secondary ion mass spectra of oxygen-containing plasma-deposited films. 
  • Lack of effect of cimetidine on acetaminophen disposition in humans. 
  • Least-square NUFFT methods applied to 2-D and 3-D radially encoded MR image reconstruction. 
  • Mapping the Oxford hip score onto the EQ-5D utility index. 
  • Mathematical modeling of triphasic viral dynamics in patients with HBeAg-positive chronic hepatitis B showing response to 24-week clevudine therapy. 
  • Medicare HMO penetration and mortality outcomes of ischemic stroke. 
  • Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients. 
  • Modified error in constitutive equations (MECE) approach for ultrasound elastography. 
  • Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices. 
  • Multimodal manifold-regularized transfer learning for MCI conversion prediction. 
  • Multivariate Curve Resolution for Signal Isolation from Fast-Scan Cyclic Voltammetric Data. 
  • Native root xylem embolism and stomatal closure in stands of Douglas-fir and ponderosa pine: mitigation by hydraulic redistribution. 
  • Obesity and dyslipidemia in behaviorally HIV-infected young women: Adolescent Trials Network study 021. 
  • Optimal apodization design for medical ultrasound using constrained least squares part I: theory. 
  • Optimal apodization design for medical ultrasound using constrained least squares part II: simulation results. 
  • Outpatient utilization patterns of integrated and split psychotherapy and pharmacotherapy for depression. 
  • Persistent cannabis users show neuropsychological decline from childhood to midlife. 
  • Pharmacodynamic evaluation of clopidogrel plus PA32540: the Spaced PA32540 With Clopidogrel Interaction Gauging (SPACING) study. 
  • Pharmacokinetic equivalence, comparable safety, and immunogenicity of an adalimumab biosimilar product (M923) to Humira in healthy subjects. 
  • Physiological correlates of HIV-related fatigue. 
  • Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept. 
  • Proton and hyperpolarized helium magnetic resonance imaging of radiation-induced lung injury in rats. 
  • Racial differences in the built environment--body mass index relationship? A geospatial analysis of adolescents in urban neighborhoods. 
  • Re-evaluating the neck injury index (NII) using experimental PMHS tests. 
  • Re-evaluating the significance of the dive response during voluntary surface apneas in the bottlenose dolphin, Tursiops truncatus. 
  • Relationship between objective and subjective sleep measures in depressed patients and healthy controls. 
  • Relationships between vitamin and mineral supplement use, dietary intake, and dietary adequacy among adolescents. 
  • Relative growth of the limbs and trunk in sifakas: heterochronic, ecological, and functional considerations. 
  • Robust two-stage estimation in hierarchical nonlinear models. 
  • Secondary analysis of case-control association studies: Insights on weighting-based inference motivate a new specification test. 
  • Secure analysis of distributed chemical databases without data integration. 
  • Self-reported energy intake by age in overweight and healthy-weight children in NHANES, 2001-2008. 
  • Short-term effects of fertilization on photosynthesis and leaf morphology of field-grown loblolly pine following long-term exposure to elevated CO(2) concentration. 
  • Social problem-solving among adolescents treated for depression. 
  • Some general estimation methods for nonlinear mixed-effects models. 
  • Sparseness prior based iterative image reconstruction for retrospectively gated cardiac micro-CT. 
  • Spirometry, Static Lung Volumes, and Diffusing Capacity. 
  • Statistical genetics of an annual plant, Impatiens capensis. II. Natural selection. 
  • Statistical methods for two-sequence three-period cross-over designs with incomplete data. 
  • System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors. 
  • Testing homogeneity of intra-run variance parameters in immunoassay. 
  • The Spiritual History Scale in four dimensions (SHS-4): validity and reliability. 
  • The effect of differences in methodology among some recent applications of shearing quotients. 
  • The effect of equipment usage and residual task difficulty on use of personal assistance, days in bed, and nursing home placement. 
  • The estimation of parameters from bulked samples. 
  • The relationship of APOE genotype to cognitive functioning in older African-American and Caucasian community residents. 
  • Time trends of incidence of age-associated diseases in the US elderly population: Medicare-based analysis. 
  • Time-varying spatial spectrum estimation with a maneuverable towed array. 
  • Trends in operative time and outcomes in minimally invasive hysterectomy from 2008 to 2018. 
  • Weighted least-squares approach for comparing correlated kappa. 
  • Women and outpatient mental health services: use by black, Hispanic, and white women in a national insured population. 
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  Keywords of People

  • Badea, Cristian Tudorel, Professor in Radiology, Biomedical Engineering
  • Johnson, G. Allan, Charles E. Putman University Distinguished Professor of Radiology, Biomedical Engineering
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology
  • Palmer, Gregory M., Associate Professor of Radiation Oncology, Radiation Oncology
  • Roy Choudhury, Kingshuk, Adjunct Associate Professor in the Department of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics