Single-Blind Method

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  Subject Areas on Research

  • A Brief Prenatal Intervention of Behavioral Change to Reduce the Risk of Maternal Cytomegalovirus: A Randomized Controlled Trial. 
  • A Multicenter, Rater-Blinded, Randomized Controlled Study of Auditory Processing-Focused Cognitive Remediation Combined With Open-Label Lurasidone in Patients With Schizophrenia and Schizoaffective Disorder. 
  • A Phase 2 Study of AMO-02 (Tideglusib) in Congenital and Childhood-Onset Myotonic Dystrophy Type 1 (DM1). 
  • A Pilot Randomized Trial of an Interactive Web-based Tool to Support Surrogate Decision Makers in the Intensive Care Unit. 
  • A Prospective Randomized Comparative Study of Three Guided Bronchoscopic Approaches for Investigating Pulmonary Nodules: The PRECISION-1 Study. 
  • A Randomized Controlled Trial to Determine the Effect of Depth of Anesthesia on Emergence Agitation in Children. 
  • A Shorter Invitation Period for AJR Manuscript Reviewers: Impact on Time to Completion of Reviews. 
  • A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds. 
  • A blinded randomized assessment of laser Doppler flowmetry efficacy in standardizing outcome from intraluminal filament MCAO in the rat. 
  • A comparison of a homemade central line simulator to commercial models. 
  • A comparison of perineometer to brink score for assessment of pelvic floor muscle strength. 
  • A comparison of ultrasound-guided and landmark-based approaches to saphenous nerve blockade: a prospective, controlled, blinded, crossover trial. 
  • A controlled trial of acute effects of human exposure to traffic particles on pulmonary oxidative stress and heart rate variability. 
  • A phase I/II study of polymerized bovine hemoglobin in adult patients with sickle cell disease not in crisis at the time of study. 
  • A physiotherapist-delivered integrated exercise and pain coping skills training intervention for individuals with knee osteoarthritis: a randomised controlled trial protocol. 
  • A physiotherapist-delivered, combined exercise and pain coping skills training intervention for individuals with knee osteoarthritis: a pilot study. 
  • A primary care "friendly" cognitive behavioral insomnia therapy. 
  • A randomised trial of peri-operative positive airway pressure for postoperative delirium in patients at risk for obstructive sleep apnoea after regional anaesthesia with sedation or general anaesthesia for joint arthroplasty. 
  • A randomized trial of exercise on well-being and function following breast cancer surgery: the RESTORE trial. 
  • A randomized trial of glutamine and antioxidants in critically ill patients. 
  • A randomized, controlled trial of a removable brace versus casting in children with low-risk ankle fractures. 
  • A scheme for categorizing traumatic military events. 
  • A video-based educational pilot for basal cell carcinoma (BCC) treatment: A randomized controlled trial. 
  • ALSUntangled No. 35: Hyperbaric Oxygen Therapy. 
  • Accuracy of glenohumeral joint injections: comparing approach and experience of provider. 
  • Accuracy of the Emergency Severity Index triage instrument for identifying elder emergency department patients receiving an immediate life-saving intervention. 
  • Achievement and maintenance of sustained response during the Treatment for Adolescents With Depression Study continuation and maintenance therapy. 
  • Additional Post-Concussion Impact Exposure May Affect Recovery in Adolescent Athletes. 
  • Adult template circumcision: a prospective, randomized, patient-blinded, comparative study evaluating the safety and efficacy of a novel circumcision device. 
  • Adverse baseline physiological and psychosocial profiles of women enrolled in a cardiac rehabilitation clinical trial. 
  • Age and African-American race impact the validity and reliability of the asthma control test in persistent asthmatics. 
  • Age effects of coronary artery bypass graft on cognitive status change among elderly male twins. 
  • Agreement Between Magnetic Resonance Imaging Proton Density Fat Fraction Measurements and Pathologist-Assigned Steatosis Grades of Liver Biopsies From Adults With Nonalcoholic Steatohepatitis. 
  • American College of Cardiology/ European Society of Cardiology international study of angiographic data compression phase I. The effects of lossy data compression on recognition of diagnostic features in digital coronary angiography. 
  • American College of Cardiology/European Society of Cardiology International Study of Angiographic Data Compression Phase I: The effect of lossy data compression on recognition of diagnostic features in digital coronary angiography. 
  • An economic analysis of an aggressive diagnostic strategy with single photon emission computed tomography myocardial perfusion imaging and early exercise stress testing in emergency department patients who present with chest pain but nondiagnostic electrocardiograms: Results from a randomized trial. 
  • An evaluation of prosthetic aortic valves using transesophageal echocardiography: the double-envelope technique. 
  • An exploratory analysis of the impact of family functioning on treatment for depression in adolescents. 
  • An open-label preliminary trial of sertraline for treatment of major depression after acute myocardial infarction (the SADHAT Trial). Sertraline Anti-Depressant Heart Attack Trial. 
  • Analysis of centromeric activity in Robertsonian translocations: implications for a functional acrocentric hierarchy. 
  • Aortic aneurysmal disease: assessment of stent-graft treatment-CT versus conventional angiography. 
  • Aortic atheroma burden and cognitive dysfunction after coronary artery bypass graft surgery. 
  • Apolipoprotein E4 polymorphism as a genetic predisposition to delirium in critically ill patients. 
  • Assessing the impact of ureteral stent design on patient comfort. 
  • Behavioral insomnia therapy for fibromyalgia patients: a randomized clinical trial. 
  • Biceps tenotomy has earlier pain relief compared to biceps tenodesis: a randomized prospective study. 
  • Brain Oxygen Optimization in Severe Traumatic Brain Injury Phase-II: A Phase II Randomized Trial. 
  • Branched-chain amino acid supplementation lowers perceived exertion but does not affect performance in untrained males. 
  • CXCL10/IP-10 is a biomarker and mediator for Kawasaki disease. 
  • Can Vascular Patterns on Preoperative Magnetic Resonance Imaging Help Predict Skin Necrosis after Nipple-Sparing Mastectomy? 
  • Caregiver-guided pain coping skills training for patients with advanced cancer: Background, design, and challenges for the CaringPals study. 
  • Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial. 
  • Cell-free DNA analysis for noninvasive examination of trisomy. 
  • Cerebral physiology of cardiac surgical patients treated with the perfluorocarbon emulsion, AF0144. 
  • Changes in quality of life, cognition and functional status following catheter ablation of atrial fibrillation. 
  • Characterization of bilateral frontal lobe cerebral oxygen saturation in patients with mild traumatic brain injury. 
  • Chemotherapy-induced splenic volume increase is independently associated with major complications after hepatic resection for metastatic colorectal cancer. 
  • Clinical and angiographic outcomes in diabetic patients following single or multivessel stenting in the COSTAR II randomized trial. 
  • Clinical and cost effectiveness of booklet based vestibular rehabilitation for chronic dizziness in primary care: single blind, parallel group, pragmatic, randomised controlled trial. 
  • Clinical aspects of MuSK antibody positive seronegative MG. 
  • Combining levodopa and virtual reality-based therapy for rehabilitation of the upper limb after acute stroke: pilot study Part II. 
  • Combining medications to enhance depression outcomes (CO-MED): acute and long-term outcomes of a single-blind randomized study. 
  • Comparative-Effectiveness of Simulation-Based Deliberate Practice Versus Self-Guided Practice on Resident Anesthesiologists' Acquisition of Ultrasound-Guided Regional Anesthesia Skills. 
  • Comparing the effects of ipragliflozin versus metformin on visceral fat reduction and metabolic dysfunction in Japanese patients with type 2 diabetes treated with sitagliptin: A prospective, multicentre, open-label, blinded-endpoint, randomized controlled study (PRIME-V study). 
  • Comparison in humans of the potency and pharmacokinetics of intravenously injected cocaethylene and cocaine. 
  • Comparison of an automated algorithm to expert physician interpretation of 80-lead body surface mapping in the evaluation of acute myocardial ischemia and infarction in patients presenting to the emergency department with chest pain: results from the Optimal Cardiovascular Diagnostic Evaluation Enabling Faster Treatment of Myocardial Infarction trial. 
  • Comparison of elliptical excision versus punch incision for the treatment of epidermal inclusion cysts: A prospective, randomized study. 
  • Comparison of pooled fresh frozen serum to proficiency testing material in College of American Pathologists surveys: cortisol and immunoglobulin E. 
  • Comparison of synovial fluid cartilage marker concentrations and chondral damage assessed arthroscopically in acute knee injury. 
  • Comparison of the safety and immunogenicity of an investigational and a licensed quadrivalent meningococcal conjugate vaccine in children 2-10 years of age. 
  • Complementary clinical benefits of coronary-artery stenting and blockade of platelet glycoprotein IIb/IIIa receptors. Evaluation of Platelet IIb/IIIa Inhibition in Stenting Investigators. 
  • Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder. 
  • Concordance of hypervascular liver nodule characterization between the organ procurement and transplant network and liver imaging reporting and data system classifications. 
  • Conditions for enhancing the encoding of an elementary motor memory by rTMS. 
  • Continuous chest compression cardiopulmonary resuscitation training promotes rescuer self-confidence and increased secondary training: a hospital-based randomized controlled trial*. 
  • Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia. 
  • Coronary Plaque Characterization in Psoriasis Reveals High-Risk Features That Improve After Treatment in a Prospective Observational Study. 
  • Correlates and outcomes of depressed out-patients with greater and fewer anxious symptoms: a CO-MED report. 
  • Cost-benefit and efficacy of aprotinin compared with epsilon-aminocaproic acid in patients having repeated cardiac operations: a randomized, blinded clinical trial. 
  • Cost-effectiveness of a preferred intensity exercise programme for young people with depression compared with treatment as usual: an economic evaluation alongside a clinical trial in the UK. 
  • Current knowledge of the platelet glycoprotein IIb/IIIa receptor antagonists for the treatment of coronary artery disease. 
  • Daily process methodology for measuring earlier antidepressant response. 
  • Daily rifapentine for treatment of pulmonary tuberculosis. A randomized, dose-ranging trial. 
  • Deep Learning Computer-aided Polyp Detection Reduces Adenoma Miss Rate: A United States Multi-center Randomized Tandem Colonoscopy Study (CADeT-CS Trial). 
  • Dental attendance among low-income women and their children following a brief motivational counseling intervention: A community randomized trial. 
  • Depression treatment in patients with general medical conditions: results from the CO-MED trial. 
  • Design issues in randomized phase II/III trials. 
  • Design of VA Cooperative Study #591: CERV-PTSD, comparative effectiveness research in veterans with PTSD. 
  • Designation and distribution of events in the Multicenter UnSustained Tachycardia Trial (MUSTT). 
  • Detection of pulmonary embolism: comparison of contrast-enhanced spiral CT and time-of-flight MR techniques. 
  • Diagnosis of canine visceral leishmaniasis with a dot-enzyme-linked immunosorbent assay. 
  • Diagnostic impact of SPECT image display on assessment of obstructive coronary artery disease. 
  • Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. 
  • Dialectical behavior therapy for high suicide risk in individuals with borderline personality disorder: a randomized clinical trial and component analysis. 
  • Differences in baseline characteristics and outcomes at 1- and 2-year follow-up of cancer survivors accrued via self-referral versus cancer registry in the FRESH START Diet and exercise trial. 
  • Differences in imaging characteristics of HPV-positive and HPV-Negative oropharyngeal cancers: a blinded matched-pair analysis. 
  • Differentiation of Diabetic Macular Edema From Pseudophakic Cystoid Macular Edema by Spectral-Domain Optical Coherence Tomography. 
  • Does antidepressant therapy improve cognition in elderly depressed patients? 
  • Does early-onset chronic or recurrent major depression impact outcomes with antidepressant medications? A CO-MED trial report. 
  • Does functional ability in the postoperative period differ between remifentanil- and fentanyl-based anesthesia? 
  • Does ketamine-mediated N-methyl-D-aspartate receptor antagonism cause schizophrenia-like oculomotor abnormalities? 
  • Early Impedance-Guided Intervention Improves Long-Term Outcome in Patients With Heart Failure. 
  • Early Self-directed Home Exercise Program After Anterior Cervical Discectomy and Fusion: A Pilot Study. 
  • Early childhood caries: analysis of psychosocial and biological factors in a high-risk population. 
  • Early normalization of Quality of Life predicts later remission in depression: Findings from the CO-MED trial. 
  • Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial. 
  • Ecological validity of neurofeedback: modulation of slow wave EEG enhances musical performance. 
  • Editorial Comment. 
  • Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial. 
  • Effect of Caloric Restriction or Aerobic Exercise Training on Peak Oxygen Consumption and Quality of Life in Obese Older Patients With Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial. 
  • Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2: A Randomized Clinical Trial. 
  • Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema: The RENEW Randomized Clinical Trial. 
  • Effect of Financial Incentives on Glucose Monitoring Adherence and Glycemic Control Among Adolescents and Young Adults With Type 1 Diabetes: A Randomized Clinical Trial. 
  • Effect of Natriuretic Peptide-Guided Therapy on Hospitalization or Cardiovascular Mortality in High-Risk Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial. 
  • Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation: A Randomized Clinical Trial. 
  • Effect of a multifaceted intervention on use of evidence-based therapies in patients with acute coronary syndromes in Brazil: the BRIDGE-ACS randomized trial. 
  • Effect of a tailored assistive technology intervention on older adults and their family caregiver: a pragmatic study protocol. 
  • Effect of an Early Palliative Care Telehealth Intervention vs Usual Care on Patients With Heart Failure: The ENABLE CHF-PC Randomized Clinical Trial. 
  • Effect of an advocacy intervention on mental health in Chinese women survivors of intimate partner violence: A randomized controlled trial 
  • Effect of an educational script on postpartum contraceptive use: a randomized controlled trial. 
  • Effect of an implantable gentamicin-collagen sponge on sternal wound infections following cardiac surgery: a randomized trial. 
  • Effect of antidepressant medication treatment on suicidal ideation and behavior in a randomized trial: an exploratory report from the Combining Medications to Enhance Depression Outcomes Study. 
  • Effect of candesartan on cause-specific mortality in heart failure patients: the Candesartan in Heart failure Assessment of Reduction in Mortality and morbidity (CHARM) program. 
  • Effect of fluconazole prophylaxis on candidiasis and mortality in premature infants: a randomized clinical trial. 
  • Effect of improving the quality of radiographic interpretation on the ability to predict pulmonary tuberculosis relapse. 
  • Effect of intrathecal fentanyl dose on the duration of labor analgesia. 
  • Effect of low versus high dialysate sodium concentration on blood pressure and endothelial-derived vasoregulators during hemodialysis: a randomized crossover study. 
  • Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial. 
  • Effect of rifampicin on S-ketamine and S-norketamine plasma concentrations in healthy volunteers after intravenous S-ketamine administration. 
  • Effectiveness of Group Problem Management Plus (Group-PM+) for adults affected by humanitarian crises in Nepal: study protocol for a cluster randomized controlled trial. 
  • Effectiveness of Sequential Psychological and Medication Therapies for Insomnia Disorder: A Randomized Clinical Trial. 
  • Effectiveness of a breath-hold monitoring system in improving the reproducibility of different breath-hold positions in multiphasic CT imaging. 
  • Effectiveness of thigh-length graduated compression stockings to reduce the risk of deep vein thrombosis after stroke (CLOTS trial 1): a multicentre, randomised controlled trial. 
  • Effects of Cuisine-Based Chinese Heart-Healthy Diet in Lowering Blood Pressure Among Adults in China: Multicenter, Single-Blind, Randomized, Parallel Controlled Feeding Trial. 
  • Effects of a caregiver-inclusive assistive technology intervention: a randomized controlled trial. 
  • Effects of an online personal health record on medication accuracy and safety: a cluster-randomized trial. 
  • Effects of dietary phosphate restriction and phosphate binders on FGF23 levels in CKD. 
  • Effects of exercise and stress management training on nighttime blood pressure dipping in patients with coronary heart disease: A randomized, controlled trial. 
  • Effects of functional taping compared with sham taping and minimal intervention on pain intensity and static postural control for patients with non-specific chronic low back pain: a randomised clinical trial protocol. 
  • Effects of postischemic halothane administration on outcome from transient focal cerebral ischemia in the rat. 
  • Effects of telerehabilitation on physical function and disability for stroke patients: a randomized, controlled trial. 
  • Effects of transcranial direct current stimulation with virtual reality on upper limb function in patients with ischemic stroke: a randomized controlled trial. 
  • Efficacy and Safety of Once-Daily Minoxidil Foam 5% Versus Twice-Daily Minoxidil Solution 2% in Female Pattern Hair Loss: A Phase III, Randomized, Investigator-Blinded Study. 
  • Efficacy and cost-effectiveness of an outcall program to reduce carer burden and depression among carers of cancer patients [PROTECT]: rationale and design of a randomized controlled trial. 
  • Efficacy and feasibility of a novel tri-modal robust exercise prescription in a retirement community: a randomized, controlled trial. 
  • Efficacy of Flecainide in the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia: A Randomized Clinical Trial. 
  • Efficacy of a telephone outcall program to reduce caregiver burden among caregivers of cancer patients [PROTECT]: a randomised controlled trial. 
  • Efficacy of finasteride 1 mg in the treatment of androgenetic alopecia in men. 
  • Electrocardiographic predictors of arrhythmic death and total mortality in the multicenter unsustained tachycardia trial. 
  • Emerging evidence on renal denervation for the treatment of hypertension. 
  • Endoscopic full-thickness plication for the treatment of gastroesophageal reflux disease: A randomized, sham-controlled trial. 
  • Enhancing Cardiac Rehabilitation With Stress Management Training: A Randomized, Clinical Efficacy Trial. 
  • Enhancing communication between oncologists and patients with a computer-based training program: a randomized trial. 
  • Estimation of the contribution of norketamine to ketamine-induced acute pain relief and neurocognitive impairment in healthy volunteers. 
  • Eszopiclone coadministered with escitalopram in patients with insomnia and comorbid generalized anxiety disorder. 
  • Evaluating disparities in door-to-EKG time for patients with noncardiac chest pain. 
  • Evaluation of eszopiclone discontinuation after cotherapy with fluoxetine for insomnia with coexisting depression. 
  • Experimental manipulations of the phenomenology of memory. 
  • Failure of glucagon-like peptide-1 to induce panic attacks or anxiety in patients with panic disorder. 
  • Family systemic psychosocial support for at-risk adolescents in Lebanon: study protocol for a multi-site randomised controlled trial. 
  • Feasibility and utility of screening for depression and anxiety disorders in patients with cardiovascular disease. 
  • Female gender is associated with impaired quality of life 1 year after coronary artery bypass surgery. 
  • Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease. 
  • Final Results of the RHAPSODY Trial: A Multi-Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke. 
  • Foot drop stimulation versus ankle foot orthosis after stroke: 30-week outcomes. 
  • Functional electrical stimulation in-bed cycle ergometry in mechanically ventilated patients: a multicentre randomised controlled trial. 
  • Gastric graft-versus-host disease: a blinded histologic study. 
  • Gated 99mTc-tetrofosmin and 18F-FDG studies: a comparison of single-acquisition and separate-acquisition protocols. 
  • Gene expression signatures that predict radiation exposure in mice and humans. 
  • Goal-Directed Fluid Therapy Using Stroke Volume Variation for Resuscitation after Low Central Venous Pressure-Assisted Liver Resection: A Randomized Clinical Trial. 
  • Group Versus Individual Physical Therapy for Veterans With Knee Osteoarthritis: Randomized Clinical Trial. 
  • Heart Failure Prevention in Older Patients Using Intensive Blood Pressure Reduction: Potential Role of Diuretics. 
  • Hemodynamics and emergence profile of remifentanil versus fentanyl prospectively compared in a large population of surgical patients. 
  • High-dose aprotinin effectively reduces blood loss during on-pump coronary artery bypass grafting with bivalirudin anticoagulation. 
  • Histological assessment of breast lesions identified exclusively by magnetic resonance. 
  • How obesity affects the cut-points for B-type natriuretic peptide in the diagnosis of acute heart failure. Results from the Breathing Not Properly Multinational Study. 
  • Hybrid Interactive and Didactic Teaching Format Improves Resident Retention and Attention Compared to Traditional Lectures. 
  • Identification of mild cognitive impairment in ACTIVE: algorithmic classification and stability. 
  • IgA and IgG1 Specific to Vi Polysaccharide of Salmonella Typhi Correlate With Protection Status in a Typhoid Fever Controlled Human Infection Model. 
  • Imagery reduces children's post-operative pain 
  • Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention. 
  • Immediate changes after manual therapy in resting-state functional connectivity as measured by functional magnetic resonance imaging in participants with induced low back pain. 
  • Impact of Baseline Characteristics on Geographic Atrophy Progression in the FILLY Trial Evaluating the Complement C3 Inhibitor Pegcetacoplan. 
  • Impact of Standardized Simulated Patients on First-Year Pharmacy Students' Knowledge Retention of Insulin Injection Technique and Counseling Skills. 
  • Impact of a depression care management program for hospitalized cardiac patients. 
  • Impact of cryopreservation on tetramer, cytokine flow cytometry, and ELISPOT. 
  • Impact of rate-modulated pacing on quality of life and exercise capacity--evidence from the Advanced Elements of Pacing Randomized Controlled Trial (ADEPT). 
  • Inadequate postgraduate training of skin and soft tissue infections in an era of community-associated methicillin-resistant Staphylococcus aureus. 
  • Incidence and Prognostic Impact of Incomplete Revascularization Documented by Coronary Angiography 1 Year After Coronary Artery Bypass Grafting. 
  • Influenza A vaccine decreases the incidence of otitis media in 6- to 30-month-old children in day care. 
  • Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program. 
  • Insulin resistance and alterations in angiogenesis: additive insults that may lead to preeclampsia. 
  • Internet-Based Vestibular Rehabilitation for Older Adults With Chronic Dizziness: A Randomized Controlled Trial in Primary Care. 
  • Internet-based vestibular rehabilitation for adults aged 50 years and over: a protocol for a randomised controlled trial. 
  • Intravascular ultrasound insights from the Cobalt Chromium Stent With Antiproliferative for Restenosis II (COSTAR II) trial comparing CoStar and Taxus paclitaxel-eluting stents. 
  • Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic Cardiomyopathy: Safety and Efficacy Results of a Phase II-A Randomized Trial. 
  • Japan-United States of America Harmonized Assessment by Randomized Multicentre Study of OrbusNEich's Combo StEnt (Japan-USA HARMONEE) study: primary results of the pivotal registration study of combined endothelial progenitor cell capture and drug-eluting stent in patients with ischaemic coronary disease and non-ST-elevation acute coronary syndrome. 
  • Jump starting shared medical appointments for diabetes with weight management: Rationale and design of a randomized controlled trial. 
  • Lack of association between patients' measured burden of disease and risk for hospital readmission. 
  • Lack of utility of symptoms and signs at first presentation as predictors of inflammatory bowel disease in secondary care. 
  • Landing biomechanics are not immediately altered by a single-dose patellar tendon isometric exercise protocol in male athletes with patellar tendinopathy: A single-blinded randomized cross-over trial. 
  • Laparo-endoscopic single-site (LESS) cholecystectomy with epidural vs. general anesthesia. 
  • Laparoscopic compared with robotic sacrocolpopexy for vaginal prolapse: a randomized controlled trial. 
  • Late safety, efficacy, and cost-effectiveness of a zotarolimus-eluting stent compared with a paclitaxel-eluting stent in patients with de novo coronary lesions: 2-year follow-up from the ENDEAVOR IV trial (Randomized, Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Taxus Paclitaxel-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions). 
  • Lidocaine lollipop as single-agent anesthesia in upper GI endoscopy. 
  • Lisdexamfetamine dimesylate augmentation in adults with persistent executive dysfunction after partial or full remission of major depressive disorder. 
  • Long-term outcomes after catheter-based renal artery denervation for resistant hypertension: final follow-up of the randomised SYMPLICITY HTN-3 Trial. 
  • Low-dose dobutamine tissue-tagged magnetic resonance imaging with 3-dimensional strain analysis allows assessment of myocardial viability in patients with ischemic cardiomyopathy. 
  • MRI evaluation of anterior knee pain: predicting response to nonoperative treatment. 
  • Main outcomes of the FRESH START trial: a sequentially tailored, diet and exercise mailed print intervention among breast and prostate cancer survivors. 
  • Mechanical bowel preparation for gynecologic laparoscopy: a prospective randomized trial of oral sodium phosphate solution vs single sodium phosphate enema. 
  • Minimal manifestation status and prednisone withdrawal in the MGTX trial. 
  • Modeling fade patterns of nipple areola complex tattoos following breast reconstruction. 
  • Modeling statin myopathy in a human skeletal muscle microphysiological system. 
  • Morning Versus Evening Bright Light Treatment at Home to Improve Function and Pain Sensitivity for Women with Fibromyalgia: A Pilot Study. 
  • Multicenter Pivotal Clinical Trial of Urine Malaria Test for Rapid Diagnosis of Plasmodium falciparum Malaria. 
  • Multicenter randomized controlled trial on Duration of Therapy for Thrombosis in Children and Young Adults (the Kids-DOTT trial): pilot/feasibility phase findings. 
  • Multiple pulmonary nodules in AIDS: usefulness of CT in distinguishing among potential causes. 
  • Needle preference in patients receiving cosmetic botulinum toxin type A. 
  • Nurse-led behavioral management of diabetes and hypertension in community practices: a randomized trial. 
  • Olanzapine on trial. 
  • On-pump versus off-pump coronary-artery bypass surgery. 
  • One-year outcome of subacromial corticosteroid injection compared with manual physical therapy for the management of the unilateral shoulder impingement syndrome: a pragmatic randomized trial. 
  • Online repetitive transcranial magnetic stimulation during working memory in younger and older adults: A randomized within-subject comparison. 
  • Onset and extent of platelet inhibition by clopidogrel loading in patients undergoing elective coronary stenting: the Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial. 
  • Onset and recovery of neuromuscular blockade after two doses of rocuronium in children. 
  • Opacification and border delineation improvement in patients with suboptimal endocardial border definition in routine echocardiography: results of the Phase III Albunex Multicenter Trial. 
  • Outcomes of a randomized controlled trial assessing a smartphone Application to reduce unmet needs among people diagnosed with CancEr (ACE). 
  • Overview of registered studies in orthodontics: Evaluation of the ClinicalTrials.gov registry. 
  • Paravertebral somatic nerve block compared with peripheral nerve blocks for outpatient inguinal herniorrhaphy. 
  • Pathologic response to preoperative chemotherapy in colorectal liver metastases: fibrosis, not necrosis, predicts outcome. 
  • Patients with asthma demonstrate airway inflammation after exposure to concentrated ambient particulate matter. 
  • Percutaneous Tibial Nerve Stimulation vs Sham Stimulation for Fecal Incontinence in Women: NeurOmodulaTion for Accidental Bowel Leakage Randomized Clinical Trial. 
  • Perflubron emulsion (AF0144) augments harvesting of autologous blood: a phase II study in cardiac surgery. 
  • Pharmacokinetic and tolerance evaluation of actisomide, a new antiarrhythmic agent, in healthy volunteers. 
  • Placebo response mitigation with a participant-focused psychoeducational procedure: a randomized, single-blind, all placebo study in major depressive and psychotic disorders. 
  • Polymerase chain reaction detection of the BCR-ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in 346 patients. 
  • Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia. 
  • Poststress measurements of left ventricular function with gated perfusion SPECT: comparison with resting measurements by using a same-day perfusion-function protocol. 
  • Potential Use of American College of Radiology BI-RADS Mammography Atlas for Reporting and Assessing Lesions Detected on Dedicated Breast CT Imaging: Preliminary Study. 
  • Prasugrel 5 mg in the very elderly attenuates platelet inhibition but maintains noninferiority to prasugrel 10 mg in nonelderly patients: the GENERATIONS trial, a pharmacodynamic and pharmacokinetic study in stable coronary artery disease patients. 
  • Pre-treatment insomnia as a predictor of single and combination antidepressant outcomes: a CO-MED report. 
  • Predicting survival after coronary revascularization for ischemic cardiomyopathy. 
  • Prediction of 30-day mortality among patients with thrombolysis-related intracranial hemorrhage. 
  • Prediction of readmissions and mortality in patients with heart failure: lessons from the IMPEDANCE-HF extended trial. 
  • Primary angiitis of the central nervous system at conventional angiography. 
  • Prognostic significance of amino acid transport imaging in patients with brain tumors. 
  • Prognostic value of quantitative contrast-enhanced cardiovascular magnetic resonance for the evaluation of sudden death risk in patients with hypertrophic cardiomyopathy. 
  • Progressive loss of synaptic integrity in human apolipoprotein E4 targeted replacement mice and attenuation by apolipoprotein E2. 
  • Prospective randomized study of mode switching in a clinical trial of pacemaker therapy for sinus node dysfunction. 
  • Protocol of a multicenter, single-blind, randomised, parallel controlled feeding trial evaluating the effect of a Chinese Healthy Heart (CHH) diet in lowering blood pressure and other cardiovascular risk factors. 
  • Psychedelic effects of ketamine in healthy volunteers: relationship to steady-state plasma concentrations. 
  • Randomised controlled trial and economic analysis of an internet-based weight management programme: POWeR+ (Positive Online Weight Reduction). 
  • Randomized Trial of Hepatic Artery Embolization for Hepatocellular Carcinoma Using Doxorubicin-Eluting Microspheres Compared With Embolization With Microspheres Alone. 
  • Randomized Trial of Pleural Fluid Drainage Frequency in Patients with Malignant Pleural Effusions. The ASAP Trial. 
  • Randomized Trial of Thymectomy in Myasthenia Gravis. 
  • Randomized comparison of selective serotonin reuptake inhibitor (escitalopram) monotherapy and antidepressant combination pharmacotherapy for major depressive disorder with melancholic features: a CO-MED report. 
  • Randomized trial of lacosamide versus fosphenytoin for nonconvulsive seizures. 
  • Randomized trial to improve fracture prevention in nursing home residents. 
  • Randomized, blinded trial comparing fondaparinux with unfractionated heparin in patients undergoing contemporary percutaneous coronary intervention: Arixtra Study in Percutaneous Coronary Intervention: a Randomized Evaluation (ASPIRE) Pilot Trial. 
  • Ranibizumab and bevacizumab for neovascular age-related macular degeneration. 
  • Ranibizumab combined with verteporfin photodynamic therapy in neovascular age-related macular degeneration (FOCUS): year 2 results. 
  • Rationale and Design of ORCHID: A Randomized Placebo-controlled Clinical Trial of Hydroxychloroquine for Adults Hospitalized with COVID-19. 
  • Rationale and design of a randomized controlled trial of allogeneic mesenchymal stem cells in patients with nonischemic cardiomyopathy. 
  • Rationale and design of the Japan-USA harmonized assessment by randomized, multicenter study of OrbusNEich's combo StEnt (Japan-USA HARMONEE): Assessment of a novel DES platform for percutaneous coronary revascularization in patients with ischemic coronary disease and non-ST-elevation acute coronary syndrome. 
  • Rationale, design, and baseline data for a multicenter randomized clinical trial comparing depression screening strategies after acute coronary syndrome: The comparison of depression identification after acute Coronary Syndromes-Quality of Life and Cost Outcomes (CODIACS-QOL) trial. 
  • Reduced need for alveolar bone grafting by presurgical orthopedics and primary gingivoperiosteoplasty. 
  • Regional cerebral blood flow response to oral amphetamine challenge in healthy volunteers. 
  • Relationship between obesity and depression: characteristics and treatment outcomes with antidepressant medication. 
  • Relationships amongst osteoarthritis biomarkers, dynamic knee joint load, and exercise: results from a randomized controlled pilot study. 
  • Reliability of early postoperative radiographic assessment of tunnel placement after anterior cruciate ligament reconstruction. 
  • Reliability of quantification measures of actinic keratosis. 
  • Reliable methods to evaluate the burden of actinic keratoses. 
  • Response inhibition predicts poor antidepressant treatment response in very old depressed patients. 
  • Risk for valvular heart disease among users of fenfluramine and dexfenfluramine who underwent echocardiography before use of medication. 
  • Rituximab as treatment for anti-MuSK myasthenia gravis: Multicenter blinded prospective review. 
  • Rivaroxaban in Patients with Atrial Fibrillation and a Bioprosthetic Mitral Valve. 
  • Role of microvolt T-wave alternans in assessment of arrhythmia vulnerability among patients with heart failure and systolic dysfunction: primary results from the T-wave alternans sudden cardiac death in heart failure trial substudy. 
  • Safety and Tolerability of Neladenoson Bialanate, a Novel Oral Partial Adenosine A1 Receptor Agonist, in Patients With Chronic Heart Failure. 
  • Safety of very early sheath removal in patients treated with REG1 for acute coronary syndromes: insights from the RADAR trial. 
  • Safety, pharmacokinetics, and immunological activities of multiple intravenous or subcutaneous doses of an anti-HIV monoclonal antibody, VRC01, administered to HIV-uninfected adults: Results of a phase 1 randomized trial. 
  • Saline vs Tissue Plasminogen Activator Irrigations after Drain Placement for Appendicitis-Associated Abscess: A Prospective Randomized Trial. 
  • Sentinel node staging of resectable colon cancer: results of a multicenter study. 
  • Sildenafil does not improve cardiomyopathy in Duchenne/Becker muscular dystrophy. 
  • Silent cerebral infarct definitions and full-scale IQ loss in children with sickle cell anemia. 
  • Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trial. 
  • Similar Effects of Thrust and Nonthrust Spinal Manipulation Found in Adults With Subacute and Chronic Low Back Pain: A Controlled Trial With Adaptive Allocation. 
  • Singapore Tele-technology Aided Rehabilitation in Stroke (STARS) trial: protocol of a randomized clinical trial on tele-rehabilitation for stroke patients. 
  • Single incision versus standard 3-port laparoscopic appendectomy: a prospective randomized trial. 
  • Single-Blind and Double-Blind Peer Review: Effects on National Representation. 
  • Sonographic Detection of Extracapsular Extension in Papillary Thyroid Cancer. 
  • Standard subcutaneous dosing of unfractionated heparin for venous thromboembolism prophylaxis in surgical ICU patients leads to subtherapeutic factor Xa inhibition. 
  • Store-and-forward teledermatology results in similar clinical outcomes to conventional clinic-based care. 
  • Strategies for supporting intervention fidelity in the rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial. 
  • Subcutaneous bupivacaine infiltration and postoperative pain perception after percutaneous nephrolithotomy. 
  • Sunitinib efficacy against advanced renal cell carcinoma. 
  • Surface normal overlap: a computer-aided detection algorithm with application to colonic polyps and lung nodules in helical CT. 
  • Suspicious ultrasound characteristics predict BRAF V600E-positive papillary thyroid carcinoma. 
  • Symptomatic Carotid Occlusion Is Frequently Associated With Microembolization. 
  • Technical skills improve after practice on virtual-reality temporal bone simulator. 
  • Texting Motivational Interviewing: A Randomized Controlled Trial of Motivational Interviewing Text Messages Designed to Augment Childhood Obesity Treatment. 
  • The "final" 5-year follow-up from the ENDEAVOR IV trial comparing a zotarolimus-eluting stent with a paclitaxel-eluting stent. 
  • The Antimicrobial Scrub Contamination and Transmission (ASCOT) Trial: A Three-Arm, Blinded, Randomized Controlled Trial With Crossover Design to Determine the Efficacy of Antimicrobial-Impregnated Scrubs in Preventing Healthcare Provider Contamination. 
  • The Cobalt chromium STent with Antiproliferative for Restenosis II (COSTAR II) trial study design: advancing the active-control evaluation of second-generation drug-eluting stents. 
  • The Concise Health Risk Tracking Self-Report (CHRT-SR) assessment of suicidality in depressed outpatients: A psychometric evaluation. 
  • The Effects of 12-Week Beta-Hydroxy-Beta-Methylbutyrate Supplementation in Patients with Liver Cirrhosis: Results from a Randomized Controlled Single-Blind Pilot Study. 
  • The Manual Therapy and Strengthening for the Hip (MASH) Trial: Protocol for a Multisite Randomized Trial of a Subgroup of Older Adults With Chronic Back and Hip Pain. 
  • The Use of Liposomal Bupivacaine Administered With Standard Bupivacaine in Ankle Fractures Requiring Open Reduction Internal Fixation: A Single-Blinded Randomized Controlled Trial. 
  • The addition of cervical unilateral posterior-anterior mobilisation in the treatment of patients with shoulder impingement syndrome: a randomised clinical trial. 
  • The clinician as investigator: participating in clinical trials in the practice setting: Appendix 1: fundamentals of study design. 
  • The comparative effects of spinal and peripheral thrust manipulation and exercise on pain sensitivity and the relation to clinical outcome: a mechanistic trial using a shoulder pain model. 
  • The effect of endoscopic olfactory cleft polyp removal on olfaction. 
  • The effect of indapamide versus hydrochlorothiazide on ventricular and arterial function in patients with hypertension and diabetes: results of a randomized trial. 
  • The effect of reactive atypia/inflammation on the laser-induced fluorescence diagnosis of non-dysplastic Barrett's esophagus. 
  • The effects of a tailored cardiac rehabilitation program on depressive symptoms in women: A randomized clinical trial. 
  • The electromechanical substrate for response to cardiac resynchronization therapy in patients with right bundle branch block. 
  • The impact of chronic depression on acute and long-term outcomes in a randomized trial comparing selective serotonin reuptake inhibitor monotherapy versus each of 2 different antidepressant medication combinations. 
  • The impact of eszopiclone on sleep and cognition in patients with schizophrenia and insomnia: a double-blind, randomized, placebo-controlled trial. 
  • The influence of history on interobserver agreement for diagnosing actinic keratoses and malignant skin lesions. 
  • The keys to healthy family child care homes intervention: study design and rationale. 
  • The limited reliability of the Ramsay scale. 
  • The mode selection trial (MOST) in sinus node dysfunction: design, rationale, and baseline characteristics of the first 1000 patients. 
  • The relationship of age, gender, and degenerative changes observed on radiographs of the shoulder in asymptomatic individuals. 
  • The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery. 
  • The role of F-18 FDG positron emission tomography in preoperative assessment of the liver in patients being considered for curative resection of hepatic metastases from colorectal cancer. 
  • The undertreatment of dysthymia. 
  • The use of bovine hemoglobin glutamer-250 (Hemopure) in surgical patients: results of a multicenter, randomized, single-blinded trial. 
  • Thoracic paravertebral block for breast surgery. 
  • Ticagrelor versus clopidogrel after fibrinolytic therapy in patients with ST-elevation myocardial infarction: Rationale and design of the ticagrelor in patients with ST elevation myocardial infarction treated with thrombolysis (TREAT) trial. 
  • Topical chemotherapy in cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine, 0.02%, gel in mycosis fungoides. 
  • Tracheal intubation following training with the GlideScope compared to direct laryngoscopy. 
  • Transesophageal assessment of left atrial thrombus using a 3.3-mm monoplane probe. 
  • Two-year outcomes after arthroscopic surgery compared to physical therapy for femoracetabular impingement: A protocol for a randomized clinical trial. 
  • Vagus nerve stimulation (VNS) for treatment-resistant depressions: a multicenter study. 
  • Veliparib with temozolomide or carboplatin/paclitaxel versus placebo with carboplatin/paclitaxel in patients with BRCA1/2 locally recurrent/metastatic breast cancer: randomized phase II study. 
  • Very Early Constraint-Induced Movement during Stroke Rehabilitation (VECTORS): A single-center RCT. 
  • X-linked hypophosphatemic rickets without "rickets". 
  • Zolpidem for persistent insomnia in SSRI-treated depressed patients. 
  • Zonisamide for weight loss in obese adults: a randomized controlled trial. 
• 

  Keywords of People

  • Clements III, Dennis Alfred, Professor Emeritus of Pediatrics, Pediatrics, General Pediatrics and Adolescent Health
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Milano, Carmelo Alessio, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology
  • Olsen, Maren Karine, Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology