Immunodominant Epitopes
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Subject Areas on Research
- A threshold for central T cell tolerance to an inducible serum protein.
- Absence of immunodominant anti-Gag p17 (SL9) responses among Gag CTL-positive, HIV-uninfected vaccine recipients expressing the HLA-A*0201 allele.
- Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses.
- Cytotoxic-T-lymphocyte-mediated elimination of target cells transduced with engineered adeno-associated virus type 2 vector in vivo.
- Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants.
- Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.
- Ethylenecarbodiimide-treated splenocytes carrying male CD4 epitopes confer histocompatibility Y chromosome antigen transplant protection by inhibiting CD154 upregulation.
- Expansion of tumor-T cell pairs from fine needle aspirates of melanoma metastases.
- Functional and molecular characterization of human monoclonal antibody reactive with the immunodominant region of HIV type 1 glycoprotein 41.
- Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
- HIV type 1 V3 region primer-induced antibody suppression is overcome by administration of C4-V3 peptides as a polyvalent immunogen.
- Hierarchy of risk of childhood-onset rheumatoid arthritis conferred by HLA-DRB1 alleles encoding the shared epitope.
- Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses.
- Immunodominance and cross-reactivity of B5703-restricted CD8 T lymphocytes from HIV type 1 subtype C-infected Ethiopians.
- Influence of HLA-C expression level on HIV control.
- Mutational analysis of the IgE-binding epitopes of P34/Gly m Bd 30K.
- Mutations in a dominant Nef epitope of simian immunodeficiency virus diminish TCR:epitope peptide affinity but not epitope peptide:MHC class I binding.
- Nasal peptide vaccination elicits CD8 responses and reduces viral burden after challenge with virulent murine cytomegalovirus.
- Potent simian immunodeficiency virus-specific cellular immune responses in the breast milk of simian immunodeficiency virus-infected, lactating rhesus monkeys.
- Primary vascularization of the graft determines the immunodominance of murine minor H antigens during organ transplantation.
- Protein structure plays a critical role in peanut allergen stability and may determine immunodominant IgE-binding epitopes.
- Recognition of a small number of diverse epitopes dominates the cytotoxic T lymphocytes response to HIV type 1 in an infected individual.
- Residues critical for duck hepatitis B virus neutralization are involved in host cell interaction.
- Role of chaperones in antigen processing.
- Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.
- Targeted Elimination of Immunodominant B Cells Drives the Germinal Center Reaction toward Subdominant Epitopes.
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Keywords of People
- Ferrari, Guido, Associate Professor of Surgery, Molecular Genetics and Microbiology