Mason-Pfizer monkey virus

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  Subject Areas on Research

  • Analysis of cellular factors that mediate nuclear export of RNAs bearing the Mason-Pfizer monkey virus constitutive transport element. 
  • Inhibition of human immunodeficiency virus Rev and human T-cell leukemia virus Rex function, but not Mason-Pfizer monkey virus constitutive transport element activity, by a mutant human nucleoporin targeted to Crm1. 
  • The betaretrovirus Mason-Pfizer monkey virus selectively excludes simian APOBEC3G from virion particles. 
  • The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences. 
  • Using viral species specificity to define a critical protein/RNA interaction surface.