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Subject Areas on Research
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A comparison of murine T-cell-depleted adult bone marrow and full-term fetal blood cells in hematopoietic engraftment and immune reconstitution.
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A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection.
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Alpha-glycosylceramides enhance the antitumor cytotoxicity of hepatic lymphocytes obtained from cancer patients by activating CD3-CD56+ NK cells in vitro.
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Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage.
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Aplastic anaemia as an autoimmune complication of thymoma.
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Association of age-dependent liver injury and fibrosis with immune cell populations.
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CD19 expression in B cells regulates atopic dermatitis in a mouse model.
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CD2-mediated IL-12-dependent signals render human gamma delta-T cells resistant to mitogen-induced apoptosis, permitting the large-scale ex vivo expansion of functionally distinct lymphocytes: implications for the development of adoptive immunotherapy strategies.
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CD4 immunophenotyping in HIV infection.
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Changes in T and non-T lymphocyte subsets following seroconversion to HIV-1: stable CD3+ and declining CD3- populations suggest regulatory responses linked to loss of CD4 lymphocytes. The Multicenter AIDS Cohort Study.
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Changes in immune parameters seen in Gulf War veterans but not in civilians with chronic fatigue syndrome.
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Characterization of banked umbilical cord blood hematopoietic progenitor cells and lymphocyte subsets and correlation with ethnicity, birth weight, sex, and type of delivery: a Cord Blood Transplantation (COBLT) Study report.
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Characterization of human CD7 transgenic mice.
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Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers.
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Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses.
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Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.
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Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome.
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Donor immune reconstitution after liver-small bowel transplantation for multiple intestinal atresia with immunodeficiency.
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Effect of a metalloporphyrin antioxidant (MnTE-2-PyP) on the response of a mouse prostate cancer model to radiation.
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Effect of influenza virus vaccine on the expression of human immunodeficiency virus co-receptor CCR5.
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Establishment of normative ranges of the healthy human immune system with comprehensive polychromatic flow cytometry profiling.
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Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation.
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Hierarchical modeling for rare event detection and cell subset alignment across flow cytometry samples.
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High cell-free virus load and robust autologous humoral immune responses in breast milk of simian immunodeficiency virus-infected african green monkeys.
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Immunologic and virologic analyses of an acutely HIV type 1-infected patient with extremely rapid disease progression.
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Immunological response in chronic fatigue syndrome following a graded exercise test to exhaustion.
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Immunoreconstitution after ritonavir therapy in children with human immunodeficiency virus infection involves multiple lymphocyte lineages.
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Influence of HIV-1 infection and cigarette smoking on leukocyte profiles in homosexual men. The Multicenter AIDS Cohort Study.
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Late effects of total body irradiation on hematopoietic recovery and immune function in rhesus macaques.
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Leukocyte rolling velocities and migration are optimized by cooperative L-selectin and intercellular adhesion molecule-1 functions.
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Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms.
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Linkage of the CCR5 Delta 32 mutation with a functional polymorphism of CD45RA.
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Longitudinal peripheral blood lymphocyte subsets correlate with decreased disease activity in juvenile dermatomyositis.
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Lymphocyte accumulation in the spleen of retinoic acid receptor-related orphan receptor gamma-deficient mice.
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Lymphocyte and monocyte subset changes during cardiopulmonary bypass: effects of aging and gender.
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Lymphocyte reconstitution following non-myeloablative hematopoietic stem cell transplantation follows two patterns depending on age and donor/recipient chimerism.
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Lymphocyte shedding from genital tract of human immunodeficiency virus-infected women: immunophenotypic and clinical correlates.
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Lymphocyte subsets in healthy children during the first 5 years of life.
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Mechanisms of immune stimulation by bacterial DNA.
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Mucosally-administered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIVSF162P3.
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NK cell activation by dendritic cell vaccine: a mechanism of action for clinical activity.
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Nasal DNA-MVA SIV vaccination provides more significant protection from progression to AIDS than a similar intramuscular vaccination.
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Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequences.
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Outcomes in two Japanese adenosine deaminase-deficiency patients treated by stem cell gene therapy with no cytoreductive conditioning.
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Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-γ+CD4+ T cell numbers during colitis development in mice.
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Phase I studies of interleukin (IL)-2 and rituximab in B-cell non-hodgkin's lymphoma: IL-2 mediated natural killer cell expansion correlations with clinical response.
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Possible extrathymic development of nonfunctional T cells in a patient with complete DiGeorge syndrome.
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Potent simian immunodeficiency virus-specific cellular immune responses in the breast milk of simian immunodeficiency virus-infected, lactating rhesus monkeys.
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Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues.
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Recovery of a human natural antibody against the noncollagenous-1 domain of type IV collagen using humanized models.
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Relationship and prognostic value of endogenous interferon-alpha, beta 2-microglobulin, and neopterin serum levels in patients with Kaposi sarcoma and AIDS.
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Safety and immunogenicity of an HLA-based HIV envelope polyvalent synthetic peptide immunogen. DATRI 010 Study Group. Division of AIDS Treatment Research Initiative.
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Secondary lymphoid-tissue chemokine (SLC) stimulates integrin alpha 4 beta 7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) under flow.
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Silica Exposure Differentially Modulates Autoimmunity in Lupus Strains and Autoantibody Transgenic Mice.
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Split tolerance induced by immunotoxin in a rhesus kidney allograft model.
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Statistical mixture modeling for cell subtype identification in flow cytometry.
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Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of neutralizing antibodies in rhesus monkeys.
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T-Cell recovery in adults and children following umbilical cord blood transplantation.
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Tandem mass spectrometry, but not T-cell receptor excision circle analysis, identifies newborns with late-onset adenosine deaminase deficiency.
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The role of ACAID and CD4+CD25+FOXP3+ regulatory T cells on CTL function against MHC alloantigens.
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Thymopoiesis in HIV-infected adults after highly active antiretroviral therapy.
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Transgenic expression of the viral FLIP MC159 causes lpr/gld-like lymphoproliferation and autoimmunity.
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Treatment of active refractory rheumatoid arthritis with humanized monoclonal antibody CAMPATH-1H administered by daily subcutaneous injection.
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Treatment of steroid-refractory acute graft-versus-host disease with anti-CD147 monoclonal antibody ABX-CBL.
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VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression.
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Virologic response of nine therapy-experienced children receiving 64 weeks of nelfinavir salvage therapy.
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mTORC2 in Thymic Epithelial Cells Controls Thymopoiesis and T Cell Development.
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Keywords of People
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Ferrari, Guido,
Professor in Surgery,
Molecular Genetics and Microbiology
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Schanberg, Laura Eve,
Professor of Pediatrics,
Pediatrics, Rheumatology
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Weinhold, Kent James,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, in the School of Medicine,
Immunology