Polymerase Chain Reaction

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  Subject Areas on Research

  • A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. 
  • A Comparative Study of Serum Exosome Isolation Using Differential Ultracentrifugation and Three Commercial Reagents. 
  • A PCR-RFLP typing method for adhesion molecule gene polymorphisms and allele frequencies in a normal UK population. 
  • A PCR-based strategy to generate integrative targeting alleles with large regions of homology. 
  • A candidate gene for congenital bilateral isolated ptosis identified by molecular analysis of a de novo balanced translocation. 
  • A comparative study of asymmetric migration events across a marine biogeographic boundary. 
  • A comparison of a new rapid real-time polymerase chain reaction system to traditional culture in determining group B streptococcus colonization. 
  • A comparison of methods for RNA extraction from lymphocytes for RT-PCR. 
  • A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity. 
  • A cross-sectional survey of Plasmodium falciparum pfcrt mutant haplotypes in the Democratic Republic of Congo. 
  • A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. 
  • A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells. 
  • A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. 
  • A genetic linkage map of the laboratory rat, Rattus norvegicus. 
  • A genetic map in the Mimulus guttatus species complex reveals transmission ratio distortion due to heterospecific interactions. 
  • A glucan synthase FKS1 homolog in cryptococcus neoformans is single copy and encodes an essential function. 
  • A high association of oncogenic human papillomaviruses with carcinomas of the female urethra: polymerase chain reaction-based analysis of multiple histological types. 
  • A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration. 
  • A human recombinant Fab identifies a human immunodeficiency virus type 1-induced conformational change in cell surface-expressed CD4. 
  • A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription. 
  • A linking function for the cellulose-binding protein SP85 in the spore coat of Dictyostelium discoideum. 
  • A map of 75 human ribosomal protein genes. 
  • A method for linking VL and VH region genes that allows bulk transfer between vectors for use in generating polyclonal IgG libraries. 
  • A missense mutation in exon 4 of the human adenosine deaminase gene causes severe combined immunodeficiency. 
  • A multimember kinesin gene family in Drosophila. 
  • A new T-cell receptor transgenic model of the CD4+ direct pathway: level of priming determines acute versus chronic rejection. 
  • A novel Ca2+/calmodulin-dependent protein kinase and a male germ cell-specific calmodulin-binding protein are derived from the same gene. 
  • A novel approach for the analysis of T-cell reconstitution by using a T-cell receptor beta-based oligonucleotide microarray in hematopoietic stem cell transplantation. 
  • A novel beta-globin mutation, beta Durham-NC [beta 114 Leu-->Pro], produces a dominant thalassemia-like phenotype. 
  • A novel mutation in the von Hippel-Lindau gene. 
  • A novel mutation of the ACADM gene (c.145C>G) associated with the common c.985A>G mutation on the other ACADM allele causes mild MCAD deficiency: a case report. 
  • A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs. 
  • A past mutation at isoleucine 397 is now a common cause of moderate/mild haemophilia B. 
  • A phase II study of capecitabine, oxaliplatin, bevacizumab and cetuximab in the treatment of metastatic colorectal cancer. 
  • A pilot study of dose-intensified procarbazine, CCNU, vincristine for poor prognosis brain tumors utilizing fibronectin-assisted, retroviral-mediated modification of CD34+ peripheral blood cells with O6-methylguanine DNA methyltransferase. 
  • A pipeline to determine RT-QPCR control genes for evolutionary studies: application to primate gene expression across multiple tissues. 
  • A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice. 
  • A potential role for interferon-alpha in the pathogenesis of HIV-associated dementia. 
  • A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies. 
  • A quality control program within a clinical trial Consortium for PCR protocols to detect Plasmodium species. 
  • A randomized study of combined zidovudine-lamivudine versus didanosine monotherapy in children with symptomatic therapy-naive HIV-1 infection. The Pediatric AIDS Clinical Trials Group Protocol 300 Study Team. 
  • A real-time PCR assay to identify and discriminate among wild-type and vaccine strains of varicella-zoster virus and herpes simplex virus in clinical specimens, and comparison with the clinical diagnoses. 
  • A recombination-based assay demonstrates that the fragile X sequence is transcribed widely during development. 
  • A simple procedure for the analysis of single nucleotide polymorphisms facilitates map-based cloning in Arabidopsis. 
  • A splice junction mutation in a new myopathic variant of phosphoglycerate kinase deficiency (PGK North Carolina). 
  • A standardized approach to PCR-based semiquantitation of multiple cytokine gene transcripts from small cell samples. 
  • A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation. 
  • A truncated isoform of c-Mpl with an essential C-terminal peptide targets the full-length receptor for degradation. 
  • A yeast cyclophilin gene essential for lactate metabolism at high temperature. 
  • ACE and ACE2 activity in diabetic mice. 
  • APOE polymorphism is associated with risk of severe sepsis in surgical patients. 
  • Aberrant promoter methylation of multiple genes in non-small cell lung cancers. 
  • Absence of a correlation of androgen receptor gene CAG repeat length and prostate cancer risk in an African-American population. 
  • Absence of mitochondrial progesterone receptor polymorphisms in women with spontaneous preterm birth. 
  • Absent ras gene mutations in human adrenal cortical neoplasms and pheochromocytomas. 
  • Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans. 
  • Acquired immunodeficiency syndrome-like illness associated with systemic Mycoplasma fermentans infection in a human immunodeficiency virus-negative homosexual man. 
  • Activation of Galpha q-coupled signaling pathways in glomerular podocytes promotes renal injury. 
  • Activation of human B cells by phosphorothioate oligodeoxynucleotides. 
  • Activin expression by cultured human retinal pigment epithelial cells. 
  • Adenylyl cyclase functions downstream of the Galpha protein Gpa1 and controls mating and pathogenicity of Cryptococcus neoformans. 
  • Advanced magnetic resonance imaging of cerebral cavernous malformations: part II. Imaging of lesions in murine models. 
  • Advantages of mRNA amplification for microarray analysis. 
  • Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl. 
  • African strains of hepatitis E virus that are distinct from Asian strains. 
  • African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity. 
  • Age distribution of latent herpes simplex virus 1 and varicella-zoster virus genome in human nervous tissue. 
  • Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice. 
  • Aggressive fibromatosis (desmoid tumor) is a monoclonal disorder. 
  • Aging and reactivation of latent murine cytomegalovirus. 
  • Allele loss on chromosome 1p36 in epithelial ovarian cancers. 
  • Allelic diversity and gene genealogy at the self-incompatibility locus in the Solanaceae. 
  • Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat. 
  • Alterations of the TP53 gene in human gliomas. 
  • Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease. 
  • Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing. 
  • Alternative splicing: a mechanism for phenotypic rescue of a common inherited defect. 
  • Alu-PCR fingerprinting of YACs. 
  • Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene. 
  • Amplification and cloning of near full-length HIV-2 genomes. 
  • Amplification of HIV-1 provirus from cerebrospinal fluid and its correlation with neurologic disease. 
  • Amplification of bacterial 16S ribosomal DNA with polymerase chain reaction. 
  • Amplification of phosphatidylinositol-specific phospholipase C-beta isoforms using degenerate primers. 
  • An Ehlers-Danlos syndrome type VIA patient with cystic malformations of the meninges. 
  • An FGF-WNT gene regulatory network controls lung mesenchyme development. 
  • An STS-based map of the human genome. 
  • An analysis of alternatively spliced CD45 mRNA transcripts during T cell maturation in humans. 
  • An approach to analysis of large-scale correlations between genome changes and clinical endpoints in ovarian cancer. 
  • An evaluation of the draft human genome sequence. 
  • An imaging-based approach to identify ligands for olfactory receptors. 
  • An improved protocol for the analysis of SOD1 gene mutations, and a new mutation in exon 4. 
  • An intronic splicing silencer causes skipping of the IIIb exon of fibroblast growth factor receptor 2 through involvement of polypyrimidine tract binding protein. 
  • An obligately photosynthetic bacterial anaerobe from a deep-sea hydrothermal vent. 
  • Analysis of European mitochondrial haplogroups with Alzheimer disease risk. 
  • Analysis of SCARECROW expression using a rapid system for assessing transgene expression in Arabidopsis roots. 
  • Analysis of association at single nucleotide polymorphisms in the APOE region. 
  • Analysis of the Stargardt disease gene (ABCR) in age-related macular degeneration. 
  • Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins. 
  • Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration. 
  • Analytical validation of a practical molecular assay prognostic of survival in nonsquamous non-small cell lung cancer. 
  • Androgen receptor mutations in androgen-independent prostate cancer: Cancer and Leukemia Group B Study 9663. 
  • Angiotensin converting enzyme and genetic hypertension: cloning of rat cDNAs and characterization of the enzyme. 
  • Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene. 
  • Apolipoprotein E gene polymorphisms are not associated with diabetic retinopathy: the atherosclerosis risk in communities study. 
  • Apolipoprotein E4 polymorphism as a genetic predisposition to delirium in critically ill patients. 
  • Aquaporin expression and freeze tolerance in Candida albicans. 
  • Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. 
  • Aspergillus DNA contamination in blood collection tubes. 
  • Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events. 
  • Assessment of genetic relatedness of vaginal isolates of Candida albicans from different geographical origins. 
  • Assessment of soil microbial community structure by use of taxon-specific quantitative PCR assays. 
  • Assessment of the COBAS Amplicor HBV Monitor Test for quantitation of serum hepatitis B virus DNA levels. 
  • Assignment of human transforming growth factor-beta type I and type III receptor genes (TGFBR1 and TGFBR3) to 9q33-q34 and 1p32-p33, respectively. 
  • Assignment of the creatine transporter gene (SLC6A8) to human chromosome Xq28 telomeric to G6PD. 
  • Association between genetic variation at the porphobilinogen deaminase gene and schizophrenia. 
  • Association between glutathione S-transferase p1 polymorphisms and lung cancer risk in Caucasians: a case-control study. 
  • Association between ratio of matrix metalloproteinase-1 to tissue inhibitor of metalloproteinase-1 and local recurrence, metastasis, and survival in human chondrosarcoma. 
  • Association of IL-1β -511 polymorphism with severe veno-occlusive disease in pediatric-matched allogeneic hematopoietic stem cell transplantation. 
  • Association of a functional CD19 polymorphism with susceptibility to systemic sclerosis. 
  • Association study of Parkin gene polymorphisms with idiopathic Parkinson disease. 
  • Associations between the genotypes of Staphylococcus aureus bloodstream isolates and clinical characteristics and outcomes of bacteremic patients. 
  • Atomic distance estimates from disulfides and high-affinity metal-binding sites in a K+ channel pore. 
  • Atypical features of familial hemophagocytic lymphohistiocytosis. 
  • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. 
  • Autophagy is essential for mitochondrial clearance in mature T lymphocytes. 
  • B cells in epithelial and perivascular compartments of human adult thymus. 
  • BRCA1 maps proximal to D17S579 on chromosome 17q21 by genetic analysis. 
  • Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. 
  • Bartonella clarridgeiae, a newly recognized zoonotic pathogen causing inoculation papules, fever, and lymphadenopathy (cat scratch disease). 
  • Bartonella henselae: etiology of pulmonary nodules in a patient with depressed cell-mediated immunity. 
  • Bartonella species in blood of immunocompetent persons with animal and arthropod contact. 
  • Bartonella vinsonii subsp. berkhoffii subsp. nov., isolated from dogs; Bartonella vinsonii subsp. vinsonii; and emended description of Bartonella vinsonii. 
  • Bcl10 is not a target for frequent mutation in human carcinomas. 
  • Beta-adrenergic receptor sequestration. A potential mechanism of receptor resensitization. 
  • Biphasic malignant meningioma: a comparative genomic hybridization study. 
  • Bisulfite pyrosequencing. 
  • Bisulfite sequencing of cloned alleles. 
  • Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism. 
  • Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis. 
  • Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial. 
  • Bronchoalveolar lavage and lung biopsy in patients with cancer and hematopoietic stem-cell transplantation recipients: a systematic review and meta-analysis. 
  • CD14-dependent mechanism for endotoxin-mediated nitric oxide synthesis in murine macrophages. 
  • CD57(+) CD4 T Cells Underlie Belatacept-Resistant Allograft Rejection. 
  • CDKN2A promoter methylation in gastric adenocarcinomas: clinical variables. 
  • CYP1B1, MYOC, and LTBP2 mutations in primary congenital glaucoma patients in the United States. 
  • Calcineurin mutants render T lymphocytes resistant to cyclosporin A. 
  • Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone. 
  • Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene. 
  • Changes in endoplasmic reticulum Ca(2-)-ATPase mRNA levels in transient cerebral ischemia of rat: a quantitative polymerase chain reaction study. 
  • Changes in thymic function with age and during the treatment of HIV infection. 
  • Characterization and Adaptation of Anaerobic Sludge Microbial Communities Exposed to Tetrabromobisphenol A. 
  • Characterization of Langerin-expressing dendritic cell subsets in the normal cornea. 
  • Characterization of a partial cDNA for lysyl hydroxylase from human skin fibroblasts; lysyl hydroxylase mRNAs are regulated differently by minoxidil derivatives and hydralazine. 
  • Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger. 
  • Characterization of an iron-sulfur cluster assembly protein (ISU1) from Schizosaccharomyces pombe. 
  • Characterization of gene expression in human trabecular meshwork using single-pass sequencing of 1060 clones. 
  • Characterization of the MFalpha pheromone of the human fungal pathogen cryptococcus neoformans. 
  • Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons. 
  • Characterization of the recalcitrant CYP1 phenotype found in Atlantic killifish (Fundulus heteroclitus) inhabiting a Superfund site on the Elizabeth River, VA. 
  • Characterization of the transmembrane orientation of aquaporin-1 using antibodies to recombinant fusion proteins. 
  • Chordoid glioma: a case report and molecular characterization of five cases. 
  • Chromium(VI) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle. 
  • Chromosomal localization of human glutamate receptor genes. 
  • Circular transcripts of the testis-determining gene Sry in adult mouse testis. 
  • Clarifying the role of ATOH7 in glaucoma endophenotypes. 
  • Clearance of HHV-8 from peripheral blood mononuclear cells with a protease inhibitor. 
  • Clinical and functional findings in choroideremia due to complete deletion of the CHM gene. 
  • Clinical and imaging findings suggesting human herpesvirus 6 encephalitis. 
  • Clinical phenotype and linkage analysis of the congenital fibrosis of the extraocular muscles in an Indian family. 
  • Clinical problem-solving. Index of suspicion. 
  • Clonal and spontaneous origins of fluconazole resistance in Candida albicans. 
  • Clonal expansion and decreased occurrence of peripheral blood gamma delta T cells of the V delta 2J delta 3 lineage in multiple sclerosis patients. 
  • Cloning and characterization of two yeast genes encoding members of the CCCH class of zinc finger proteins: zinc finger-mediated impairment of cell growth. 
  • Cloning and expression of a functional serotonin transporter from rat brain. 
  • Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters. 
  • Cloning and functional characterization of a cocaine-sensitive dopamine transporter. 
  • Cloning and sequence analysis of the human beta 1-adrenergic receptor 5'-flanking promoter region. 
  • Cloning and sequencing of V genes from anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: location of lysine residues and implications for radiolabeling. 
  • Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues. 
  • Cloning of a novel alpha 1-subunit of the voltage-dependent calcium channel from the beta-cell. 
  • Cloning of cDNA and analysis of the gene for mouse angiotensin II type 2 receptor. 
  • Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor. 
  • Cobalamin inhibition of HIV-1 integrase and integration of HIV-1 DNA into cellular DNA. 
  • Coexistence of macular corneal dystrophy types I and II in a single sibship. 
  • Collagenase 1 and collagenase 3 expression in a guinea pig model of osteoarthritis. 
  • Combinatorial codon scrambling enables scalable gene synthesis and amplification of repetitive proteins. 
  • Common variation in Nemo-like kinase is associated with risk of ovarian cancer. 
  • Comparative analysis of the primate X-inactivation center region and reconstruction of the ancestral primate XIST locus. 
  • Comparative evolutionary analysis of chalcone synthase and alcohol dehydrogenase loci in Arabidopsis, Arabis, and related genera (Brassicaceae). 
  • Comparative genomic hybridization studies in hydatidiform moles and choriocarcinoma: amplification of 7q21-q31 and loss of 8p12-p21 in choriocarcinoma. 
  • Comparative value of tumour grade, hormonal receptors, Ki-67, HER-2 and topoisomerase II alpha status as predictive markers in breast cancer patients treated with neoadjuvant anthracycline-based chemotherapy. 
  • Comparison of PCR, culture, and histopathology for diagnosis of tuberculous pericarditis. 
  • Comparison of conventional and integrated fixed-film activated sludge systems: attached- and suspended-growth functions and quantitative polymerase chain reaction measurements. 
  • Comparison of cytomegalovirus polymerase chain reaction and serology for screening umbilical cord blood components. 
  • Comparison of human immunodeficiency virus 1 DNA polymerase chain reaction and qualitative and quantitative RNA polymerase chain reaction in human immunodeficiency virus 1-exposed infants. 
  • Comparison of real-time PCR and microscopy for malaria parasite detection in Malawian pregnant women. 
  • Comparison of the Digene Hybrid Capture System Cytomegalovirus (CMV) DNA (version 2.0), Roche CMV UL54 analyte-specific reagent, and QIAGEN RealArt CMV LightCycler PCR reagent tests using AcroMetrix OptiQuant CMV DNA quantification panels and specimens from allogeneic-stem-cell transplant recipients. 
  • Comparison of use of phenotypic and genotypic characteristics for identification of species of the anamorph genus Candida and related teleomorph yeast species. 
  • Comprehensive analysis of chromosome 1p deletions in neuroblastoma. 
  • Concessions of an alpha male? Cooperative defence and shared reproduction in multi-male primate groups. 
  • Confirmation of TBK1 duplication in normal tension glaucoma. 
  • Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant: further clarifications. 
  • Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. 
  • Constitutively active mutants of the alpha 2-adrenergic receptor. 
  • Context-dependent activation kinetics elicited by soluble versus outer membrane vesicle-associated heat-labile enterotoxin. 
  • Contribution of hedgehog signaling to the establishment of left-right asymmetry in the sea urchin. 
  • Correct splicing despite mutation of the invariant first nucleotide of a 5' splice site: a possible basis for disparate clinical phenotypes in siblings with adenosine deaminase deficiency. 
  • Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal. 
  • Cryptococcus neoformans mitochondrial superoxide dismutase: an essential link between antioxidant function and high-temperature growth. 
  • Cryptococcus neoformans shows a remarkable genotypic diversity in Brazil. 
  • Cultured porcine trabecular meshwork cells display altered lysosomal function when subjected to chronic oxidative stress. 
  • Cutaneous acquired toxoplasmosis in a child: a case report and review of the literature. 
  • Cyanobacterial ribosomal RNA genes with multiple, endonuclease-encoding group I introns. 
  • Cyclic AMP-dependent protein kinase catalytic subunits have divergent roles in virulence factor production in two varieties of the fungal pathogen Cryptococcus neoformans. 
  • Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2. 
  • Cytochrome P450IIIA activity and cytokine-mediated synthesis of nitric oxide. 
  • Cytogenetic and molecular analysis of inv dup(15) chromosomes observed in two patients with autistic disorder and mental retardation. 
  • Cytokine mRNA expression in postischemic/reperfused myocardium. 
  • Cytokine production at the site of disease in human tuberculosis. 
  • Cytomegalovirus retinitis associated with Hodgkin's disease. 
  • D2 dopamine receptors in the human retina: cloning of cDNA and localization of mRNA. 
  • DNA damage in peripheral blood mononuclear cells correlates with response to biochemotherapy in melanoma. 
  • DNA typing for HLA-A and HLA-B identifies disparities between patients and unrelated donors matched by HLA-A and HLA-B serology and HLA-DRB1. 
  • DNA- and PCR-fingerprinting in fungi. 
  • Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease. 
  • Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency. 
  • Deletion and site-directed mutagenesis of the ATP-binding motif (P-loop) in the bifunctional murine ATP-sulfurylase/adenosine 5'-phosphosulfate kinase enzyme. 
  • Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration. 
  • Deletion of cyclin-dependent kinase 4 inhibitor genes P15 and P16 in non-Hodgkin's lymphoma. 
  • Delimiting species without nuclear monophyly in Madagascar's mouse lemurs. 
  • Derivation of a biologically contained replication system for human immunodeficiency virus type 1. 
  • Design and implementation of high-throughput RNAi screens in cultured Drosophila cells. 
  • Detailed analysis of gene expression during development of T cell lineages in the thymus. 
  • Detecting colorectal cancer in stool with the use of multiple genetic targets. 
  • Detection of APC mutations in fecal DNA from patients with colorectal tumors. 
  • Detection of BK polyomavirus after kidney transplantation: a comparison of urine electron microscopy with plasma polymerase chain reaction. 
  • Detection of Bartonella species in the blood of veterinarians and veterinary technicians: a newly recognized occupational hazard? 
  • Detection of DNA damage in transcriptionally active genes by RT-PCR and assessment of repair of cisplatin-induced damage in the glutathione S-transferase-pi gene in human glioblastoma cells. 
  • Detection of HIV-2 by PCR. 
  • Detection of Helicobacter pylori gastritis by PCR: correlation with inflammation scores and immunohistochemical and CLOtest findings. 
  • Detection of RAS mutations in archival testicular germ cell tumors by polymerase chain reaction and oligonucleotide hybridization. 
  • Detection of allelic variations of human gene expression by polymerase colonies. 
  • Detection of culture-resistant bacterial pathogens by amplification and sequencing of ribosomal DNA. 
  • Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms. 
  • Detection of human papillomavirus in the prostate by polymerase chain reaction and in situ hybridization. 
  • Detection of immunoglobulin kappa light chain rearrangements by polymerase chain reaction. An improved method for detecting clonal B-cell lymphoproliferative disorders. 
  • Detection of minor drug-resistant populations by parallel allele-specific sequencing. 
  • Detection of mouse cytomegalovirus nucleic acid in latently infected mice by in vitro enzymatic amplification. 
  • Determination of aromatase cytochrome P450 messenger ribonucleic acid in human breast tissue by competitive polymerase chain reaction amplification. 
  • Determination of estrogen receptor messenger ribonucleic acid (mRNA) and cytochrome P450 aromatase mRNA levels in adipocytes and adipose stromal cells by competitive polymerase chain reaction amplification. 
  • Development and application of a phylogenomic toolkit: resolving the evolutionary history of Madagascar's lemurs. 
  • Development of a multiplex PCR assay for the simultaneous detection and discrimination of HIV-1, HIV-2, HTLV-I and HTLV-II. 
  • Developmental changes in the extent of RNA editing of glutamate receptor subunit GluR5 in rat brain. 
  • Developmental changes of RNA editing of glutamate receptor subunits GluR5 and GluR6: in vivo versus in vitro. 
  • Developmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancer. 
  • Developmental regulation of the gibberellin biosynthetic gene GA1 in Arabidopsis thaliana. 
  • Developmental toxicity and DNA damage from exposure to parking lot runoff retention pond samples in the Japanese medaka (Oryzias latipes). 
  • Diagnosis and Treatment of Acute Retinal Necrosis: A Report by the American Academy of Ophthalmology. 
  • Diagnosis of fungal infection: new technologies for the mycology laboratory. 
  • Diagnosis of human congenital cytomegalovirus infection by amplification of viral DNA from dried blood spots on perinatal cards. 
  • Diagnosis of placental malaria in poorly fixed and processed placental tissue. 
  • Diagnostic potential of prostate-specific antigen expressing epithelial cells in blood of prostate cancer patients. 
  • Diagnostic vitrectomy in the management of ocular disease. 
  • Diagnostic yield of vitrectomy in eyes with suspected posterior segment infection or malignancy. 
  • Dideoxy fingerprinting assay for BRCA1 mutation analysis. 
  • Differences in intraepithelial lymphocyte T cell subsets isolated from murine small versus large intestine. 
  • Different methods of sample preparation influence sensitivity of Mycobacterium tuberculosis and Borrelia burgdorferi PCR. 
  • Different spectra of genomic deletions within the CCM genes between Italian and American CCM patient cohorts. 
  • Differential collagen I gene expression in fetal fibroblasts. 
  • Differential display RT-PCR for identifying novel gene expression in the lung. 
  • Differential effects of prostaglandin E2-sensitive receptors on contractility of human ocular cells that regulate conventional outflow. 
  • Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines. 
  • Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes. 
  • Differential gene expression in mouse sclera during ocular development. 
  • Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues. 
  • Differential induction of mRNAs for the glycolytic and ethanolic fermentative pathways by hypoxia and anoxia in maize seedlings. 
  • Differential regulation of inducible nitric oxide synthase gene expression by ethanol in the human intestinal epithelial cell line DLD-1. 
  • Differential requirement for STAT by gain-of-function and wild-type receptor tyrosine kinase Torso in Drosophila. 
  • Differentially methylated regions of imprinted genes in prenatal, perinatal and postnatal human tissues. 
  • Differing molecular pathology of pancreatic adenocarcinoma in Egyptian and United States patients. 
  • Digital image analysis for rapid quantification of total RNA and cDNA for SMART-PCR. 
  • Direct PCR sequencing with boronated nucleotides. 
  • Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees. 
  • Directed evolution of a pyruvate aldolase to recognize a long chain acyl substrate. 
  • Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis. 
  • Dissemination of an Enterococcus Inc18-Like vanA plasmid associated with vancomycin-resistant Staphylococcus aureus. 
  • Distal nephron renal tumors: microsatellite allelotype. 
  • Distribution of WDR36 DNA sequence variants in patients with primary open-angle glaucoma. 
  • Distribution of binding sites for thromboxane A2 in the mouse kidney. 
  • Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States. 
  • Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardium. 
  • Diversification of Ig superfamily genes in an invertebrate. 
  • Diversity and detection of nitrate assimilation genes in marine bacteria. 
  • Diversity and phylogenetic affinities of foliar fungal endophytes in loblolly pine inferred by culturing and environmental PCR. 
  • Does HLA-dependent chimerism underlie the pathogenesis of juvenile dermatomyositis? 
  • Donor polymorphisms in Toll-like receptor-4 influence the development of rejection after renal transplantation. 
  • Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease? 
  • Dr(a-) polymorphism of decay accelerating factor. Biochemical, functional, and molecular characterization and production of allele-specific transfectants. 
  • Dual infection with Ehrlichia chaffeensis and a spotted fever group rickettsia: a case report. 
  • Dynamics and elasticity of the fibronectin matrix in living cell culture visualized by fibronectin-green fluorescent protein. 
  • Dysbindin gene (DTNBP1) and schizophrenia in Korean population. 
  • EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival. 
  • ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum. 
  • ESR1 promoter hypermethylation does not predict atypia in RPFNA nor persistent atypia after 12 months tamoxifen chemoprevention. 
  • Effect of anti-V3 antibodies on cell-free and cell-to-cell human immunodeficiency virus transmission. 
  • Effect of type 1 transforming growth factor-beta on the level of aromatase cytochrome P-450 in human fetal hepatocytes. 
  • Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques. 
  • Effects of age and parasitemia on nitric oxide production/leukocyte nitric oxide synthase type 2 expression in asymptomatic, malaria-exposed children. 
  • Effects of diethylstilbestrol on rat granulosa cell and thecal/interstitial cell transforming growth factor-beta 2 mRNA expression in vivo: analysis by reverse transcription-polymerase chain reaction. 
  • Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes. 
  • Ehlers-Danlos syndrome type VI results from a nonsense mutation and a splice site-mediated exon-skipping mutation in the lysyl hydroxylase gene. 
  • Ehrlichia chaffeensis, a new species associated with human ehrlichiosis. 
  • Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency. 
  • Elevation of cAMP is required for down-regulation, but not agonist-induced desensitization, of endogenous dopamine D1 receptors in opossum kidney cells. Studies in cells that stably express a rat cAMP phosphodiesterase (rPDE3) cDNA. 
  • Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission. 
  • Elovl4 5-bp-deletion knock-in mice develop progressive photoreceptor degeneration. 
  • Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States. 
  • Emergence of the keratinocyte growth factor multigene family during the great ape radiation. 
  • Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage. 
  • Endotoxin-mediated synthesis of nitric oxide is dependent on Gq protein signal transduction. 
  • Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha. 
  • Enhancer control of local accessibility to V(D)J recombinase. 
  • Enteroviral meningoencephalitis as a complication of X-linked hyper IgM syndrome. 
  • Epidermal denervation and its effects on keratinocytes and Langerhans cells. 
  • Epidermal growth factor promotes uncoupling from adenylyl cyclase of the rat D2S receptor expressed in GH4C1 cells. 
  • Epigenetic detection of human chromosome 14 uniparental disomy. 
  • Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients. 
  • Erythrocyte Webb-type glycophorin C variant lacks N-glycosylation due to an asparagine to serine substitution. 
  • Essential light chain of Drosophila nonmuscle myosin II. 
  • Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. 
  • Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation. 
  • Etiology of the mutational spectrum of ras genes in human carcinomas. 
  • Evaluating and enhancing ribozyme reaction efficiency in mammalian cells. 
  • Evaluation of human T cell lymphotropic virus infection in a cohort of injecting drug users. 
  • Evaluation of pertussis in U.S. Marine Corps trainees. 
  • Evaluation of the beta2-adrenergic receptor gene as a candidate glaucoma gene in 2 ancestral populations. 
  • Evidence for genetic heterogeneity supports clinical differences in congenital myasthenic syndromes. 
  • Evidence for independent recruitment of zeta-crystallin/quinone reductase (CRYZ) as a crystallin in camelids and hystricomorph rodents. 
  • Evidence that SOX2 overexpression is oncogenic in the lung. 
  • Evolution of the CCU from rhythm, function and protection to reperfusion and beyond: a personal journey and perspective. 
  • Exclusion of lumican and fibromodulin as candidate genes in MYP3 linked high grade myopia. 
  • Exclusion of maternal uniparental disomy of chromosome 14 in patients referred for Prader-Willi syndrome using a multiplex methylation polymerase chain reaction assay. 
  • Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 
  • Exon circularization in mammalian nuclear extracts. 
  • Exon skipping in purine nucleoside phosphorylase mRNA processing leading to severe immunodeficiency. 
  • Expansion of CTG18.1 Trinucleotide Repeat in TCF4 Is a Potent Driver of Fuchs' Corneal Dystrophy. 
  • Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2. 
  • Experimental challenge and clinical cases of Bohle iridovirus (BIV) in native Australian anurans. 
  • Expression in Escherichia coli of the thermostable DNA polymerase from Pyrococcus furiosus. 
  • Expression of CD44 and variant isoforms in cultured human retinal pigment epithelial cells. 
  • Expression of CD44 variants in human inflammatory synovitis. 
  • Expression of a candidate sex-determining gene during mouse testis differentiation. 
  • Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers. 
  • Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer. 
  • Expression of cytokine mRNA in murine splenic dendritic cells and better induction of T cell-derived cytokines by dendritic cells than by macrophages during in vitro costimulation assay using specific antigens. 
  • Expression of human protein phosphatase-1 in Saccharomyces cerevisiae highlights the role of phosphatase isoforms in regulating eukaryotic functions. 
  • Expression of multidrug resistance gene mdr1 mRNA in a subset of normal bone marrow cells. 
  • Expression of normal and novel glucokinase mRNAs in anterior pituitary and islet cells. 
  • Expression of three forms of melanoma growth stimulating activity (MGSA)/gro in human retinal pigment epithelial cells. 
  • Expression, purification, and in vitro assays of mitochondrial single-stranded DNA-binding protein. 
  • Extensive recombination due to heteroduplexes generates large amounts of artificial gene fragments during PCR. 
  • Extent of RNA editing of glutamate receptor subunit GluR5 in different brain regions of the rat. 
  • Extrahippocampal involvement in human herpesvirus 6 encephalitis depicted at MR imaging. 
  • Factors affecting harp seal (Pagophilus groenlandicus) strandings in the Northwest Atlantic. 
  • Familial antiphospholipid antibody syndrome: criteria for disease and evidence for autosomal dominant inheritance. 
  • Familial transmission of the FMR1 CGG repeat. 
  • Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype. 
  • Fine ambient particles induce oxidative stress and metal binding genes in human alveolar macrophages. 
  • Fine localization of the CMT4A locus using a PAC contig and haplotype analysis. 
  • Fine mapping of Wilms' tumors with 16q loss of heterozygosity localizes the putative tumor suppressor gene to a region of 6.7 megabases. 
  • Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P. 
  • Fine-structure mapping of meiosis-specific double-strand DNA breaks at a recombination hotspot associated with an insertion of telomeric sequences upstream of the HIS4 locus in yeast. 
  • First report of Yersinia ruckeri biotype 2 in the USA. 
  • Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids. 
  • Focusing HIV prevention on those most likely to transmit the virus. 
  • Four new adenosine deaminase mutations, altering a zinc-binding histidine, two conserved alanines, and a 5' splice site. 
  • Frequency of breast cancer attributable to BRCA1 in a population-based series of American women. 
  • Frequency of homozygous deletion at p16/CDKN2 in primary human tumours. 
  • Frequent detection of bcl-2/JH translocations in human blood and organ samples by a quantitative polymerase chain reaction assay. 
  • Frequent detection of tumor cells in hematopoietic grafts in neuroblastoma and Ewing's sarcoma. 
  • Frequent loss of heterozygosity on chromosome arm 18q in squamous cell carcinomas. Identification of 2 regions of loss--18q11.1-q12.3 and 18q21.1-q23. 
  • Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. 
  • Functional significance of erythropoietin receptor expression in breast cancer. 
  • Fungal community analysis by large-scale sequencing of environmental samples. 
  • Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin. 
  • Gene and protein expressions of nitric oxide synthases in ischemia-reperfused peripheral nerve of the rat. 
  • Gene disruption with PCR products in Saccharomyces cerevisiae. 
  • Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction. 
  • Gene expression patterns that characterize advanced stage serous ovarian cancers. 
  • Gene targeting of a CFTR allele in HT29 human epithelial cells. 
  • Generation of melanoma-specific, cytotoxic CD4(+) T helper 2 cells: requirement of both HLA-DR15 and Fas antigens on melanomas for their lysis by Th2 cells. 
  • Generation of random mutant libraries with multiple primers in a single reaction. 
  • Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. 
  • Genetic cause of a juvenile form of Tay-Sachs disease in a Lebanese child. 
  • Genetic changes in contralateral bronchioloalveolar carcinomas of the lung. 
  • Genetic diagnosis in Lafora disease: genotype-phenotype correlations and diagnostic pitfalls. 
  • Genetic factors contribute to bleeding after cardiac surgery. 
  • Genetic instability of microsatellites in endometrial carcinoma. 
  • Genetic recombination of poliovirus in a cell-free system. 
  • Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae. 
  • Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer. 
  • Genetic structure of typical and atypical populations of Candida albicans from Africa. 
  • Genetic subtyping of human immunodeficiency virus using a heteroduplex mobility assay. 
  • Genetic variability of Bacillus anthracis and related species. 
  • Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: risk and prognosis prediction. 
  • Genome rearrangements caused by interstitial telomeric sequences in yeast. 
  • Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. 
  • Genome-wide localization of replication factors. 
  • Genome-wide search for CLN2, the gene causing late-infantile neuronal ceroid-lipofuscinosis (LNCL). 
  • Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF). 
  • Genomics and expression profiles of the Hedgehog and Notch signaling pathways in sea urchin development. 
  • Genotypic analysis of tumor suppressor genes PTEN/MMAC1 and p53 in head and neck squamous cell carcinomas. 
  • Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression. 
  • Glucose metabolism gene variants modulate the risk of pancreatic cancer. 
  • Glucose-dependent insulinotropic peptide (GIP) gene expression in the rat salivary gland. 
  • Glutathione S-transferase polymorphisms and survival in primary malignant glioma. 
  • Glutathione regulates susceptibility to oxidant-induced mitochondrial DNA damage in human lymphocytes. 
  • Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion. 
  • Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV. 
  • Growth, survival and viral load in symptomatic childhood human immunodeficiency virus infection. 
  • H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury. 
  • HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites. 
  • HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. 
  • HIV infection--induced posttranslational modification of T cell signaling molecules associated with disease progression. 
  • HIV quasispecies and resampling. 
  • HIV-1 extrachromosomal 2-LTR circular DNA is long-lived in human macrophages. 
  • HLA-A0201 positive pancreatic cell lines: new findings and discrepancies. 
  • HNF-3 beta as a regulator of floor plate development. 
  • Hb Catonsville (glutamic acid inserted between Pro-37(C2)alpha and Thr-38(C3)alpha). Nonallelic gene conversion in the globin system? 
  • Hedgehog signaling patterns mesoderm in the sea urchin. 
  • Helper Th1 and Th2 cell responses following mucosal or systemic immunization with cholera toxin. 
  • Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1. 
  • Hemeoxygenase expression after reversible ischemia of rat brain. 
  • Hemoglobin sickle-Lepore: report of two siblings and review of the literature. 
  • Hepatitis B core antibody positive donors as a safe and effective therapeutic option to increase available organs for lung transplantation. 
  • Heterogeneity of dopamine receptors. 
  • High expression of tumor necrosis factor-related apoptosis-inducing ligand is associated with favorable ovarian cancer survival. 
  • High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice. 
  • High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer. 
  • High throughput functional analysis of HIV-1 env genes without cloning. 
  • High-resolution comparative physical mapping of mouse chromosome 10 in the region of homology with human chromosome 21. 
  • High-throughput detection of glutathione s-transferase polymorphic alleles in a pediatric cancer population. 
  • High-throughput pooling and real-time PCR-based strategy for malaria detection. 
  • Histiocytic sarcoma arising in indolent small B-cell lymphoma: report of two cases with molecular/genetic evidence suggestive of a 'transdifferentiation' during the clonal evolution. 
  • Histologic and molecular assessment of human thymus. 
  • Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. 
  • Human colonic biota studied by ribosomal DNA sequence analysis. 
  • Human granulosa-luteal and cumulus cells express transforming growth factors-beta type 1 and type 2 mRNA. 
  • Human herpesvirus 6 polymerase chain reaction findings in human immunodeficiency virus associated neurological disease and multiple sclerosis. 
  • Human lung cancer cell lines exhibit resistance to retinoic acid treatment. 
  • Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. 
  • Human papillomavirus in early laryngeal carcinoma. 
  • Human papillomavirus types 16 and 18 are not involved in human prostate carcinogenesis: analysis of archival human prostate cancer specimens by differential polymerase chain reaction. 
  • Human papillomavirus types important in progression of inverted papilloma. 
  • Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1. 
  • Human smooth muscle alpha-actin gene is a transcriptional target of the p53 tumor suppressor protein. 
  • Human type 2 angiotensin II receptor gene: cloned, mapped to the X chromosome, and its mRNA is expressed in the human lung. 
  • Hybridization probes for conventional DNA fingerprinting used as single primers in the polymerase chain reaction to distinguish strains of Cryptococcus neoformans. 
  • Hydrothermal vent fields and chemosynthetic biota on the world's deepest seafloor spreading centre. 
  • Hypoxia in the thymus: role of oxygen tension in thymocyte survival. 
  • IFN-gamma production in response to neuropathogenic Cas-Br-M murine leukemia virus infection. 
  • IGF1 (CA)19 repeat and IGFBP3 -202 A/C genotypes and the risk of prostate cancer in Black and White men. 
  • IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia. 
  • Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors. 
  • Identification and characterization of a widely expressed form of adenylyl cyclase. 
  • Identification and mapping of type 1 neurofibromatosis (NF1) homologous loci. 
  • Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system. 
  • Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine. 
  • Identification of Histoplasma capsulatum from culture extracts by real-time PCR. 
  • Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor. 
  • Identification of a new family of protein phosphatase 2A regulatory subunits. 
  • Identification of a nonsense mutation at codon 128 of the Norrie's disease gene in a male infant. 
  • Identification of a novel trimeric autotransporter adhesin in the cryptic genospecies of Haemophilus. 
  • Identification of a rat glomerular mesangial cell mitogenic 5-HT2A receptor. 
  • Identification of a region of genetic variability among Bacillus anthracis strains and related species. 
  • Identification of adenylyl cyclases by amplification using degenerate primers. 
  • Identification of amino acid residues involved in structural and ubiquinone-binding functions of subunit IV of the cytochrome bc1 complex from Rhodobacter sphaeroides. 
  • Identification of amino acids essential for calmodulin binding and activation of smooth muscle myosin light chain kinase. 
  • Identification of an alternate promoter in the rat androgen-binding protein/sex hormone-binding globulin gene that regulates synthesis of a messenger RNA encoding a protein with altered function. 
  • Identification of clinical strains of Candida albicans by DNA fingerprinting with the polymerase chain reaction. 
  • Identification of genes associated with ovarian cancer metastasis using microarray expression analysis. 
  • Identification of genes from the fungal pathogen Cryptococcus neoformans related to transmigration into the central nervous system. 
  • Identification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach. 
  • Identification of new mamu-DRB alleles using DGGE and direct sequencing. 
  • Identification of novel genes preferentially expressed in the retina using a custom human retina cDNA microarray. 
  • Identification of p18 INK4c as a tumor suppressor gene in glioblastoma multiforme. 
  • Identification of pathogenic yeasts of the imperfect genus Candida by polymerase chain reaction fingerprinting. 
  • Identification of the promoter region of the human betaIGH3 gene. 
  • Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals. 
  • Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases. 
  • Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites. 
  • Identifying human immunodeficiency virus infection at birth: application of polymerase chain reaction to Guthrie cards. 
  • Immunity of patients surviving 20 to 30 years after allogeneic or syngeneic bone marrow transplantation. 
  • Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum. 
  • Immunohistochemical and genetic analysis of non-small cell and small cell gallbladder carcinoma and their precursor lesions. 
  • Impact of IL28B gene polymorphisms on interferon-λ3 plasma levels during pegylated interferon-α/ribavirin therapy for chronic hepatitis C in patients coinfected with HIV. 
  • Impact of change to molecular testing for Clostridium difficile infection on healthcare facility-associated incidence rates. 
  • Improvements to the differential display method for gene analysis. 
  • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells. 
  • In vitro analysis of the human antiporcine T-cell repertoire. 
  • In vitro selection of RNA epitopes using autoimmune patient serum. 
  • In vitro selection of aptamers from RNA libraries. 
  • Increased p53 protein does not correlate to p53 gene mutations in microdissected human testicular germ cell tumors. 
  • Independent effects of complement factor H Y402H polymorphism and cigarette smoking on risk of age-related macular degeneration. 
  • Induction and spontaneous regression of intense pulmonary neuroendocrine cell differentiation in a model of preneoplastic lung injury. 
  • Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation. 
  • Induction of ferritin and heme oxygenase-1 by endotoxin in the lung. 
  • Induction of interleukin-6 mRNA in rat alveolar macrophages by in vitro exposure to both Cryptococcus neoformans and anti-C. neoformans antiserum. 
  • Induction of the human heat shock promoter HSP70B by nutritional stress: implications for cancer gene therapy. 
  • Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. 
  • Infectious disease pathology. 
  • Influence of actin cytoskeletal integrity on matrix metalloproteinase-2 activation in cultured human trabecular meshwork cells. 
  • Infrequent RAS oncogene mutations in human prostate cancer. 
  • Inherited human complement C5 deficiency. Nonsense mutations in exons 1 (Gln1 to Stop) and 36 (Arg1458 to Stop) and compound heterozygosity in three African-American families. 
  • Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor. 
  • Initial amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of embryonic duck hepatocytes is increased by cell cycle progression. 
  • Initiation of antiretroviral therapy during primary HIV-1 infection induces rapid stabilization of the T-cell receptor beta chain repertoire and reduces the level of T-cell oligoclonality. 
  • Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer. 
  • Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes. 
  • Integration of statistical theory and practical clinical expertise. Polymerase chain reaction testing of the HIV-exposed infant. 
  • Inter-laboratory comparison of DNA preservation in archival paraffin-embedded human brain tissue from participating centres on four continents. 
  • Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer. 
  • Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults. 
  • Interferon regulatory factor-1 up-regulates angiotensin II type 2 receptor and induces apoptosis. 
  • Interferon regulatory factors are transcriptional regulators of adipogenesis. 
  • Intergenic transcribed spacer PCR ribotyping for differentiation of Saccharomyces species and interspecific hybrids. 
  • Interleukin 1-induced production of nitric oxide inhibits benzenetriol-mediated oxidative injury in rat hepatocytes. 
  • Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides. 
  • Intralysosomal iron induces lysosomal membrane permeabilization and cathepsin D-mediated cell death in trabecular meshwork cells exposed to oxidative stress. 
  • Investigation of the basis of virulence in serotype A strains of Cryptococcus neoformans from apparently immunocompetent individuals. 
  • Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. 
  • Isolated sulfite oxidase deficiency: mutation analysis and DNA-based prenatal diagnosis. 
  • Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled. 
  • Isolation and characterization of an Ehrlichia sp. from a patient diagnosed with human ehrlichiosis. 
  • Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family. 
  • Isolation and initial characterization of the 5' flanking region of the human and murine cyclic guanosine monophosphate-phosphodiesterase beta-subunit genes. 
  • Isolation of Cryptococcus gattii and Cryptococcus neoformans var. grubii from the flowers and bark of Eucalyptus trees in India. 
  • Isolation of genes negatively or positively co-expressed with human recombination activating gene 1 (RAG1) by differential display PCR (DD RT-PCR). 
  • Isolation of monoclonal antibodies with predetermined conformational epitope specificity. 
  • Isolation of song-regulated genes in the brain of songbirds. 
  • Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. 
  • Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. 
  • Kinetics of cytokine expression in melanoma metastases classifies immune responsiveness. 
  • Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes. 
  • Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. 
  • LOC387715/HTRA1 and complement factor H variants in patients with age-related macular degeneration seen at the mayo clinic. 
  • Lack of association between LOXL1 gene polymorphisms and primary open angle glaucoma in the Saudi Arabian population. 
  • Lack of evidence for a polymorphism at codon 160 of human O6-alkylguanine-DNA alkyltransferase gene in normal tissue and cancer. 
  • Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations. 
  • Lamivudine plus zidovudine compared with zalcitabine plus zidovudine in patients with HIV infection. A randomized, double-blind, placebo-controlled trial. North American HIV Working Party. 
  • Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. 
  • Leptotrichia endocarditis: report of two cases from the International Collaboration on Endocarditis (ICE) database and review of previous cases. 
  • Linkage localization of X-linked Charcot-Marie-Tooth disease. 
  • Linkage of a mild late-onset phenotype of Fuchs corneal dystrophy to a novel locus at 5q33.1-q35.2. 
  • Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22. 
  • Linkage of scapuloperoneal spinal muscular atrophy to chromosome 12q24.1-q24.31. 
  • Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1. 
  • Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase. 
  • Localization of alpha 2-adrenergic receptor subtypes in the anterior segment of the human eye with selective antibodies. 
  • Long-term exposure of chemokine CXCL10 causes bronchiolitis-like inflammation. 
  • Longitudinal studies of Plasmodium falciparum malaria in pregnant women living in a rural Cameroonian village with high perennial transmission. 
  • Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice. 
  • Loss of heterozygosity at chromosome segment Xq25-26.1 in advanced human ovarian carcinomas. 
  • Loss of p53 in benzene-induced thymic lymphomas in p53+/- mice: evidence of chromosomal recombination. 
  • Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. 
  • Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows. 
  • Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3',5'-monophosphate-dependent phosphorylation. 
  • LvGroucho and nuclear beta-catenin functionally compete for Tcf binding to influence activation of the endomesoderm gene regulatory network in the sea urchin embryo. 
  • Lymphatic mapping and sentinel node identification for colorectal cancer. 
  • Lysis and lysis inhibition in bacteriophage T4: rV mutations reside in the holin t gene. 
  • MHC class II alleles associated with clinical and immunological manifestations of HIV-1 infection among children in Catalonia, Spain. 
  • MMP20 and ARMS2/HTRA1 Are Associated with Neovascular Lesion Size in Age-Related Macular Degeneration. 
  • Major expansion of CD8+ T cells with a predominant V beta usage during the primary immune response to HIV. 
  • Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses. 
  • Malaria surveillance in the Democratic Republic of the Congo: comparison of microscopy, PCR, and rapid diagnostic test. 
  • Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor. 
  • Manganese superoxide dismutase (MnSOD: Ala-9Val) gene polymorphism may not be associated with schizophrenia and tardive dyskinesia. 
  • Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes. 
  • Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer. 
  • MeCP2 reinforces STAT3 signaling and the generation of effector CD4+ T cells by promoting miR-124-mediated suppression of SOCS5. 
  • Measurement of mouse T cell receptor excision circles. 
  • Mechanical and chemical unfolding of a single protein: a comparison. 
  • Mechanism of inactivation of CDKN2 and MTS2 in non-small cell lung cancer and association with advanced stage. 
  • Medium-chain acyl-CoA dehydrogenase deficiency: postmortem diagnosis in a case of sudden infant death and neonatal diagnosis of an affected sibling. 
  • Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae. 
  • Mekk3 is essential for early embryonic cardiovascular development. 
  • Membrane localization and topology of a viral assembly protein. 
  • Messenger RNA repair and restoration of protein function by spliceosome-mediated RNA trans-splicing. 
  • Metabolic capacity regulates iron homeostasis in endothelial cells. 
  • Metabolism of polybrominated diphenyl ethers (PBDEs) by human hepatocytes in vitro. 
  • Methods for precise sizing, automated binning of alleles, and reduction of error rates in large-scale genotyping using fluorescently labeled dinucleotide markers. FUSION (Finland-U.S. Investigation of NIDDM Genetics) Study Group. 
  • Methylation-specific PCR. 
  • Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition. 
  • Mice with duplications and deletions at the Tme locus have altered MnSOD activity. 
  • MicroRNAs in endometrial cancers from black and white patients. 
  • Microarray analysis of endometrial carcinomas and mixed mullerian tumors reveals distinct gene expression profiles associated with different histologic types of uterine cancer. 
  • Microchimerism in sensitized renal patients. 
  • Microfluidic platform versus conventional real-time polymerase chain reaction for the detection of Mycoplasma pneumoniae in respiratory specimens. 
  • Microsatellite analysis of childhood brain tumors. 
  • Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders. 
  • Mitochondrial genetic background in Ghanaian patients with primary open-angle glaucoma. 
  • Mitochondrial polymorphism A10398G and Haplogroup I are associated with Fuchs' endothelial corneal dystrophy. 
  • Modification of peanut allergen Ara h 3: effects on IgE binding and T cell stimulation. 
  • Modulation of oncogene and tumor suppressor gene expression in a hamster model of chronic lung injury with varying degrees of pulmonary neuroendocrine cell hyperplasia. 
  • Molecular analysis of Bardet-Biedl syndrome families: report of 21 novel mutations in 10 genes. 
  • Molecular analysis of P16(Ink4)/CDKN2 and P15(INK4B)/MTS2 genes in primary human testicular germ cell tumors. 
  • Molecular analysis of highly enriched populations of T-cell-depleted monocytes. 
  • Molecular analysis of recombination in a family with Duchenne muscular dystrophy and a large pericentric X chromosome inversion. 
  • Molecular analysis of spontaneous nephrotropic anti-laminin antibodies in an autoimmune MRL-lpr/lpr mouse. 
  • Molecular approaches for colorectal cancer screening. 
  • Molecular basis of adenosine deaminase deficiency. 
  • Molecular basis of reduced or absent expression of decay-accelerating factor in Cromer blood group phenotypes. 
  • Molecular characterization of chordoma xenografts generated from a novel primary chordoma cell source and two chordoma cell lines. 
  • Molecular characterization of the human delta opioid receptor in lung cancer. 
  • Molecular characterization of the tumor-suppressive function of nischarin in breast cancer. 
  • Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain. 
  • Molecular cloning and expression of the gene for a human D1 dopamine receptor. 
  • Molecular cloning of dimethyl sulfoxide reductase from Rhodobacter sphaeroides. 
  • Molecular cloning of rat glucose-dependent insulinotropic peptide (GIP). 
  • Molecular cloning, chromosomal mapping, and characterization of the human cardiac-specific homeobox gene hCsx. 
  • Molecular defects underlying the Kell null phenotype. 
  • Molecular genetic analysis of two human sperm fibrous sheath proteins, AKAP4 and AKAP3, in men with dysplasia of the fibrous sheath. 
  • Molecular genetic and immunohistochemical analysis of the tumor suppressor genes Rb and p53 in palmar and aggressive fibromatosis. 
  • Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization. 
  • Molecular genetic studies of major histocompatibility complex genes in children with juvenile dermatomyositis: increased risk associated with HLA-DQA1 *0501. 
  • Molecular markers of prognosis in astrocytic tumors. 
  • Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination. 
  • Molecular mycology: DNA probes and applications of PCR technology. 
  • Molecular profiling of activated olfactory neurons identifies odorant receptors for odors in vivo. 
  • Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase. 
  • Molecular typing of clinical adenovirus specimens by an algorithm which permits detection of adenovirus coinfections and intermediate adenovirus strains. 
  • Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. 
  • Monocyte-induced cytokine expression in cultured human retinal pigment epithelial cells. 
  • Morphological and genomic characterization of Filobasidiella depauperata: a homothallic sibling species of the pathogenic cryptococcus species complex. 
  • Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines. 
  • Mouse keratin 4 is necessary for internal epithelial integrity. 
  • Mouse small eye results from mutations in a paired-like homeobox-containing gene. 
  • Multicenter clinical validation of PITX2 methylation as a prostate specific antigen recurrence predictor in patients with post-radical prostatectomy prostate cancer. 
  • Multicenter study to determine disk diffusion and broth microdilution criteria for prediction of high- and low-level mupirocin resistance in Staphylococcus aureus. 
  • Multicentre surveillance of the prevalence and molecular epidemiology of macrolide resistance among pharyngeal isolates of group A streptococci in the USA. 
  • Multiple genetic lesions in acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma. 
  • Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy. 
  • Multiplex PCR to diagnose bloodstream infections in patients admitted from the emergency department with sepsis. 
  • Multiplexed real-time polymerase chain reaction on a digital microfluidic platform. 
  • Multivariate analysis of associations of 42 genes in ADHD, ODD and conduct disorder. 
  • Murine typhus and febrile illness, Nepal. 
  • Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line. 
  • Mutation and expression analysis of the endoglin gene in hereditary hemorrhagic telangiectasia reveals null alleles. 
  • Mutation and overexpression of p53 in early-stage epithelial ovarian cancer. 
  • Mutation detection with MutH, MutL, and MutS mismatch repair proteins. 
  • Mutation of p53 gene in hepatocellular carcinoma cell lines with HBX DNA. 
  • Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias. 
  • Mutation of the p53 tumor-suppressor gene is not a feature of endometrial hyperplasias. 
  • Mutation screening of patients with Leber Congenital Amaurosis or the enhanced S-Cone Syndrome reveals a lack of sequence variations in the NRL gene. 
  • Mutational analysis of NPHS2 and WT1 in frequently relapsing and steroid-dependent nephrotic syndrome. 
  • Mutational analysis of the fractalkine chemokine domain. Basic amino acid residues differentially contribute to CX3CR1 binding, signaling, and cell adhesion. 
  • Mutational hot spot potential of a novel base pair mutation of the CSPG2 gene in a family with Wagner syndrome. 
  • Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS). 
  • Mutations in purine nucleoside phosphorylase deficiency. 
  • Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae. 
  • Mutations in the gene encoding for the beta 2-adrenergic receptor in normal and asthmatic subjects. 
  • Mutations of the E-cadherin gene in human gynecologic cancers. 
  • Mutations of the Ki-ras oncogene in endometrial carcinoma. 
  • Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly. 
  • Mutations of the p16 gene product are rare in prostate cancer. 
  • Mycobacterium tuberculosis polymerase chain reaction findings in neurosarcoidosis. 
  • Myocardial NF-κB activation is essential for zebrafish heart regeneration. 
  • Myocilin mutations in black South Africans with POAG. 
  • N7-cyanoborane-2'-deoxyguanosine 5'-triphosphate is a good substrate for DNA polymerase. 
  • NADiA ProsVue prostate-specific antigen slope is an independent prognostic marker for identifying men at reduced risk of clinical recurrence of prostate cancer after radical prostatectomy. 
  • NF1-related locus on chromosome 15. 
  • NOV (CCN3) regulation in the growth plate and CCN family member expression in cartilage neoplasia. 
  • NPAS1 regulates branching morphogenesis in embryonic lung. 
  • National Department of Defense Surveillance for Invasive Streptococcus pneumoniae: antibiotic resistance, serotype distribution, and arbitrarily primed polymerase chain reaction analyses. 
  • Nature and distribution of large sequence polymorphisms in Saccharomyces cerevisiae. 
  • Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells. 
  • Netrin-1 and peripheral nerve regeneration in the adult rat. 
  • Neuroprotective effects of group III mGluR in traumatic neuronal injury. 
  • New nitrogen-fixing microorganisms detected in oligotrophic oceans by amplification of Nitrogenase (nifH) genes. 
  • New polymorphic short tandem repeats for PCR-based Charcot-Marie-Tooth disease type 1A duplication diagnosis. 
  • Newborn, carrier, and early childhood screening recommendations for fragile X. 
  • Next generation multilocus sequence typing (NGMLST) and the analytical software program MLSTEZ enable efficient, cost-effective, high-throughput, multilocus sequencing typing. 
  • Next-generation sequencing of the human olfactory receptors. 
  • Nitric oxide synthase 2(Lambaréné) (G-954C), increased nitric oxide production, and protection against malaria. 
  • No association between polymorphisms in the serotonin transporter gene and susceptibility to cocaine dependence among African-American individuals. 
  • No evidence for maternal-fetal microchimerism in infantile hemangioma: a molecular genetic investigation. 
  • Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. 
  • Nonrandom distribution of interhomolog recombination events induced by breakage of a dicentric chromosome in Saccharomyces cerevisiae. 
  • North Carolina macular dystrophy (MCDR1) locus: a fine resolution genetic map and haplotype analysis. 
  • Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression. 
  • Novel integrase-defective lentiviral episomal vectors for gene transfer. 
  • Novel splicing, missense, and deletion mutations in seven adenosine deaminase-deficient patients with late/delayed onset of combined immunodeficiency disease. Contribution of genotype to phenotype. 
  • Nucleotide sequence of mouse SCIP cDNA, a POU-domain transcription factor. 
  • Nucleotide variation at the myrosinase-encoding locus, TGG1, and quantitative myrosinase enzyme activity variation in Arabidopsis thaliana. 
  • Numerous group I introns with variable distributions in the ribosomal DNA of a lichen fungus. 
  • OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas. 
  • Ocular phenotype correlations in patients with TWIST versus FGFR3 genetic mutations. 
  • Oncogenic human papillomavirus type 16 is associated with squamous cell cancer of the male urethra. 
  • Oncogenic human papillomaviruses are rarely associated with squamous cell carcinoma of the bladder: evaluation by differential polymerase chain reaction. 
  • Ontogenesis of prolactin receptors in the human fetus in early gestation. Implications for tissue differentiation and development. 
  • Organization of the human zeta-crystallin/quinone reductase gene (CRYZ). 
  • Outbreak of febrile respiratory illness associated with human adenovirus type 14p1 in Gansu Province, China. 
  • Ovarian adenocarcinomas in the laying hen and women share similar alterations in p53, ras, and HER-2/neu. 
  • Overexpression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block. 
  • Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity. 
  • Overexpression of folate binding protein and mesothelin are associated with uterine serous carcinoma. 
  • Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion. 
  • P pili in uropathogenic E. coli are composite fibres with distinct fibrillar adhesive tips. 
  • PCR analysis of egyptian respiratory adenovirus isolates, including identification of species, serotypes, and coinfections. 
  • PCR based determination of mitochondrial DNA copy number in multiple species. 
  • PCR-Based Analysis of Mitochondrial DNA Copy Number, Mitochondrial DNA Damage, and Nuclear DNA Damage. 
  • PCR-restriction fragment length polymorphism (RFLP) analyses reveal both extensive clonality and local genetic differences in Candida albicans. 
  • PG27, an extract of Tripterygium wilfordii hook f, induces antigen-specific tolerance in bone marrow transplantation in mice. 
  • Pancreatic adenocarcinoma cell line, MDAPanc-28, with features of both acinar and ductal cells. 
  • Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies. 
  • Paradoxical expression of adenosine deaminase in T cells cultured from a patient with adenosine deaminase deficiency and combine immunodeficiency. 
  • Parallel evolution at multiple levels in the origin of hummingbird pollinated flowers in Ipomoea. 
  • Parasite clearance following treatment with sulphadoxine-pyrimethamine for intermittent preventive treatment in Burkina-Faso and Mali: 42-day in vivo follow-up study. 
  • Parkin mutations and susceptibility alleles in late-onset Parkinson's disease. 
  • Partitioned pulsed-field gel electrophoresis-PCR (PPF-PCR): a new method for pulsed-field mapping for STS and microsatellites. 
  • Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED). 
  • Pathogenesis of Cryptococcus neoformans is associated with quantitative differences in multiple virulence factors. 
  • Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome. 
  • Pcp1p, an Spc110p-related calmodulin target at the centrosome of the fission yeast Schizosaccharomyces pombe. 
  • Performance of a commercial polymerase chain reaction test for endocervical Chlamydia trachomatis infection in a university hospital population. 
  • Performance of polymerase chain reaction techniques detecting perforin in the diagnosis of acute renal rejection: a meta-analysis. 
  • Peroxidative stress selectively down-regulates the neuronal stress response activated under conditions of endoplasmic reticulum dysfunction. 
  • Persistence of attenuated rev genes in a human immunodeficiency virus type 1-infected asymptomatic individual. 
  • Persistent expression of MNF identifies myogenic stem cells in postnatal muscles. 
  • Pervasive genomic recombination of HIV-1 in vivo. 
  • Pharmacologic manipulation of ob expression in a dietary model of obesity. 
  • Phenol sulfotransferases: hormonal regulation, polymorphism, and age of onset of breast cancer. 
  • Phenotypic and functional consequences of herpesvirus saimiri infection of human CD8+ cytotoxic T lymphocytes. 
  • Phylogenetic analysis of feline immunodeficiency virus in feral and companion domestic cats of New Zealand. 
  • Phylogenetic evidence for the transfer of Pseudomonas cocovenenans (van Damme et al. 1960) to the genus Burkholderia as Burkholderia cocovenenans (van Damme et al. 1960) comb. nov. 
  • Phylogenetic relationships, morphological incongruence, and geographic speciation in the fontinalaceae (Bryophyta). 
  • Phylogeny of twenty Thermus isolates constructed from 16S rRNA gene sequence data. 
  • Phylogeography of the Solanaceae-infecting Basidiomycota fungus Rhizoctonia solani AG-3 based on sequence analysis of two nuclear DNA loci. 
  • Physiological genomics of cardiac disease: quantitative relationships between gene expression and left ventricular hypertrophy. 
  • Plasmids for expression of chimeric and truncated kinesin proteins. 
  • Platelet-derived growth factor in fibrous musculoskeletal disorders: a study of pathologic tissue sections and in vitro primary cell cultures. 
  • Polarized monocyte response to cytokine stimulation. 
  • Polymerase chain reaction adjustment in antimalarial trials: molecular malarkey? 
  • Polymerase chain reaction analysis of distal vaginal specimens: a less invasive strategy for detection of Trichomonas vaginalis. 
  • Polymerase chain reaction fingerprinting in fungi using single primers specific to minisatellites and simple repetitive DNA sequences: strain variation in Cryptococcus neoformans. 
  • Polymorphism in the serotonin transporter gene and moderators of prolactin response to meta-chlorophenylpiperazine in African-American cocaine abusers and controls. 
  • Polymorphism of adhesion molecule CD31 and its role in acute graft-versus-host disease. 
  • Polymorphisms of p21 and p27 jointly contribute to an earlier age at diagnosis of pancreatic cancer. 
  • Population, behavioural and environmental drivers of malaria prevalence in the Democratic Republic of Congo. 
  • Porcine granulosa cells do not express transforming growth factor-beta 2 (TGF-beta 2) messenger ribonucleic acid: molecular basis for their inability to produce TGF-beta activity comparable to that of rat granulosa cells. 
  • Positive and negative selection LYS5MX gene replacement cassettes for use in Saccharomyces cerevisiae. 
  • Postmitotic expression of ankyrinR and beta R-spectrin in discrete neuronal populations of the rat brain. 
  • Posttransplant lymphoproliferative disorder after umbilical cord blood transplantation in children. 
  • Posttransplant lymphoproliferative disorder following nonmyeloablative allogeneic stem cell transplantation. 
  • Potent inhibition of human immunodeficiency virus type 1 (HIV-1) replication by inducible expression of HIV-1 PR multimers. 
  • Poxvirus genomes encode a secreted, soluble protein that preferentially inhibits beta chemokine activity yet lacks sequence homology to known chemokine receptors. 
  • Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines. 
  • Precocious osteoarthritis in a family with recurrent COL2A1 mutation. 
  • Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial. 
  • Prenatal diagnosis and carrier detection for glycogen storage disease type III using polymorphic DNA markers. 
  • Prenatal diagnosis of glycogen storage disease type IV using PCR-based DNA mutation analysis. 
  • Prenatal diagnosis using fetal cells from the maternal circulation. 
  • Prenatal exclusion of Ehlers-Danlos syndrome type VI by mutational analysis. 
  • Preparation and screening of an arrayed human genomic library generated with the P1 cloning system. 
  • Preparation, resonance assignment, and preliminary dynamics characterization of residue specific 13C/15N-labeled elongated DNA for the study of sequence-directed dynamics by NMR. 
  • Presence of genes encoding the panton-valentine leukocidin exotoxin is not the primary determinant of outcome in patients with complicated skin and skin structure infections due to methicillin-resistant Staphylococcus aureus: results of a multinational trial. 
  • Presence of human papillomavirus predicts recurrence of inverted papilloma. 
  • Prevalence and characterization of metallo-beta-lactamases in clinical isolates of pseudomonas aeruginosa. 
  • Prevalence of factor V G1691A (Leiden), prothrombin G20210A, and methylene tetrahydrofolate reductase C677T thrombophilic mutations in children with inflammatory bowel disease. 
  • Prevalence of human papillomavirus types 16 and 18 in squamous-cell carcinoma of the penis: a retrospective analysis of primary and metastatic lesions by differential polymerase chain reaction. 
  • Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir. 
  • Prevalence of myocilin mutations in adults with primary open-angle glaucoma in Ghana, West Africa. 
  • Prevention of graft-versus-host disease by peptides binding to class II major histocompatibility complex molecules. 
  • Primary induction of CD4 T cell responses in nasal associated lymphoid tissue during group A streptococcal infection. 
  • Primary systemic therapy in breast cancer: past lessons and new approaches. 
  • Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction. 
  • Primer3 on the WWW for general users and for biologist programmers. 
  • Primer3--new capabilities and interfaces. 
  • Probable exclusion of GLC1A as a candidate glaucoma gene in a family with middle-age-onset primary open-angle glaucoma. 
  • Probe directed at a segment of Rickettsia rickettsii rRNA amplified with polymerase chain reaction. 
  • Production and role of cytokines in the CNS of mice with acute viral encephalomyelitis. 
  • Prognostic implications of chromosome 17p deletions in human medulloblastomas. 
  • Prolactin receptor gene expression in the fetal rat. 
  • Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells. 
  • Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics. 
  • Prostaglandin F2 alpha receptors in the human trabecular meshwork. 
  • Prostate specific antigen: a decade of discovery--what we have learned and where we are going. 
  • Protein expression and functional analysis of the FHIT gene in human tumor cells. 
  • Protein fabrication automation. 
  • Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type I. 
  • Protein kinase C and Ca2+ activation of mucin secretion in airway goblet cells. 
  • QTL Mapping in Three Rice Populations Uncovers Major Genomic Regions Associated with African Rice Gall Midge Resistance. 
  • Quality of DNA extracted from mouthwashes. 
  • Quantification of Plasmodium falciparum histidine-rich protein-2 in cerebrospinal spinal fluid from cerebral malaria patients. 
  • Quantitation of hepatitis B viremia and emergence of YMDD variants in patients with chronic hepatitis B treated with lamivudine. 
  • Quantitation of residual white cells in filtered blood components by polymerase chain reaction amplification of HLA DQ-A DNA. 
  • Quantitation of target molecules from polymerase chain reaction-based limiting dilution assays. 
  • Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma. 
  • Quantitative analysis of the calcium-sensing receptor messenger RNA in parathyroid adenomas. 
  • R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models. 
  • RNA editing of glutamate receptor subunits GluR2, GluR5 and GluR6 in transient cerebral ischemia in the rat. 
  • RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue. 
  • RNA interference and single particle tracking analysis of hepatitis C virus endocytosis. 
  • RNA subunit of mitochondrial RNA-processing enzyme is induced by contractile activity in striated muscle. 
  • RalA regulates vascular endothelial growth factor-C (VEGF-C) synthesis in prostate cancer cells during androgen ablation. 
  • Randomization and selection of RNA to identify targets for RRM RNA-binding proteins and antibodies. 
  • Rapid 16S ribosomal DNA sequencing from a single colony without DNA extraction or purification. 
  • Rapid freezing of whole blood or buffy coat samples for polymerase chain reaction and cell culture analysis: application to detection of human immunodeficiency virus in blood donor and recipient repositories. The Transfusion Safety Study Group. 
  • Rapid identification of Candida species by DNA fingerprinting with PCR. 
  • Rapid identification of pathogenic fungi directly from cultures by using multiplex PCR. 
  • Rapid mapping of insertional mutations to probe cell wall regulation in Cryptococcus neoformans. 
  • Rapid molecular detection of tuberculosis and rifampin resistance. 
  • Rapid, comprehensive analysis of human cytokine mRNA and its application to the study of acute renal allograft rejection. 
  • Rat thecal/interstitial cells express transforming growth factor-beta type 1 and 2, but only type 2 is regulated by gonadotropin in vitro. 
  • Rational testing of the HIV-exposed infant. 
  • Re: Detection of human papillomavirus in squamous neoplasm of the penis. 
  • Receptor class desensitization of leukocyte chemoattractant receptors. 
  • Recombinant poxvirus boosting of DNA-primed rhesus monkeys augments peak but not memory T lymphocyte responses. 
  • Recombination of 4p16 DNA markers in an unusual family with Huntington disease. 
  • Recruitment of marrow-derived endothelial cells to experimental choroidal neovascularization by local expression of vascular endothelial growth factor. 
  • Recurrent nonsense mutations at arginine residues cause severe hemophilia B in unrelated hemophiliacs. 
  • Refinement of map position of the human GluR6 kainate receptor gene (GRIK2) and lack of association and linkage with idiopathic generalized epilepsies. 
  • Regional differences in the extent of RNA editing of the glutamate receptor subunits GluR2 and GluR6 in rat brain. 
  • Regulated expression of G protein-coupled receptor kinases (GRK's) and beta-arrestins in osteoblasts. 
  • Regulated heat shock protein 27 expression in human retinal pigment epithelium. 
  • Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. 
  • Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. 
  • Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation. 
  • Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction amplification. 
  • Removal of polymerase-produced mutant sequences from PCR products. 
  • Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus. 
  • Renal epithelium is a previously unrecognized site of HIV-1 infection. 
  • Repair of double-strand breaks in bacteriophage T4 by a mechanism that involves extensive DNA replication. 
  • Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy. 
  • Replication of the TCF4 intronic variant in late-onset Fuchs corneal dystrophy and evidence of independence from the FCD2 locus. 
  • Replication of the recessive STBMS1 locus but with dominant inheritance. 
  • Replication studies in longevity: puzzling findings in Danish centenarians at the 3'APOB-VNTR locus. 
  • Research resource: nuclear receptor atlas of human retinal pigment epithelial cells: potential relevance to age-related macular degeneration. 
  • Respiratory fungal infections: molecular diagnostic tests. 
  • Respiratory syncytial virus: an important cause of acute respiratory illness among young adults undergoing military training. 
  • Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity. 
  • Retinoic acid modulation of alpha(1-->2) fucosyltransferase activity and sensitivity of tumor cells to LAK-mediated cytotoxicity. 
  • Retinoic acid receptor alpha in acute promyelocytic leukemia. 
  • Retroviral gene transduction of circulating progenitor cells in patients with metastatic breast cancer. 
  • Retrovirus-elicited interleukin-12 and tumour necrosis factor-alpha as inducers of interferon-gamma-mediated pathology in mouse AIDS. 
  • Rev and the fate of pre-mRNA in the nucleus: implications for the regulation of RNA processing in eukaryotes. 
  • Rhodopsin maturation antagonized by dominant rhodopsin mutants. 
  • Ribosomal DNA sequence analysis of mucosa-associated bacteria in Crohn's disease. 
  • Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursors. 
  • Role of JAK3 in CD40-mediated signaling. 
  • Role of subunit-9 of mitochondrial ATP synthase in Batten disease. 
  • Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd. 
  • S-allele diversity in a natural population of Physalis crassifolia (Solanaceae) (ground cherry) assessed by RT-PCR. 
  • S-allele sequence diversity in natural populations of Solanum carolinense (Horsenettle). 
  • SANDO: another presentation of mitochondrial disease. 
  • SLE nephritis is associated with an oligoclonal expansion of intrarenal T cells. 
  • SOCS3 inhibiting migration of A549 cells correlates with PYK2 signaling in vitro. 
  • Saturation mutagenesis of His114 of EcoRI reveals relaxed-specificity mutants. 
  • Selection of strains for quality assessment of the disk induction method for detection of inducible clindamycin resistance in Staphylococci: a CLSI collaborative study. 
  • Selective mutations in cloned and expressed alpha-macroglobulin receptor binding fragment alter binding to either the alpha2-macroglobulin signaling receptor or the low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor. 
  • Self-collection of vaginal swabs for the detection of Chlamydia, gonorrhea, and trichomoniasis: opportunity to encourage sexually transmitted disease testing among adolescents. 
  • Semiquantitative measurement of cytokine messenger RNA in endomyocardium and peripheral blood mononuclear cells from human heart transplant recipients. 
  • Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma. 
  • Sequence-based differentiation of strains in the Mycobacterium avium complex. 
  • Sequencing analysis of the ATOH7 gene in individuals with optic nerve hypoplasia. 
  • Sequential development of histiocytic sarcoma and diffuse large b-cell lymphoma in a patient with a remote history of follicular lymphoma with genotypic evidence of a clonal relationship: a divergent (bilineal) neoplastic transformation of an indolent B-cell lymphoma in a single individual. 
  • Sequential gene profiling of basal cell carcinomas treated with imiquimod in a placebo-controlled study defines the requirements for tissue rejection. 
  • Serotype AD strains of Cryptococcus neoformans are diploid or aneuploid and are heterozygous at the mating-type locus. 
  • Simultaneous amplification of four DNA repair genes and beta-actin in human lymphocytes by multiplex reverse transcriptase-PCR. 
  • Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia. 
  • Six novel mutations in the endoglin gene in hereditary hemorrhagic telangiectasia type 1 suggest a dominant-negative effect of receptor function. 
  • Slip-sliding away: serial changes and homoplasy in repeat number in the Drosophila yakuba homolog of human cancer susceptibility gene BRCA2. 
  • Small changes in expression affect predisposition to tumorigenesis. 
  • Snapshot of the allele-specific variation in human gene expression. 
  • Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers. 
  • Speciation on a local geographic scale: the evolution of a rare rock outcrop specialist in Mimulus. 
  • Species and genotypic diversities and similarities of pathogenic yeasts colonizing women. 
  • Species identification and virulence attributes of Saccharomyces boulardii (nom. inval.). 
  • Specific 33-residue repeat(s) of erythrocyte ankyrin associate with the anion exchanger. 
  • Specific binding of the human T-cell leukemia virus type I Rex protein to a short RNA sequence located within the Rex-response element. 
  • Spectrum of mutations in the Batten disease gene, CLN3. 
  • Spinal cord trauma activates processing of xbp1 mRNA indicative of endoplasmic reticulum dysfunction. 
  • Strategy for elucidating differentially expressed genes in leiomyomata identified by microarray technology. 
  • Structure of the gene encoding the human leukocyte adhesion molecule-1 (TQ1, Leu-8) of lymphocytes and neutrophils. 
  • Structure of the human allelic glutathione S-transferase-pi gene variant, hGSTP1 C, cloned from a glioblastoma multiforme cell line. 
  • Structure, function, and phylogeny of the mating locus in the Rhizopus oryzae complex. 
  • Structure-function relationships of the complement regulatory protein, CD59. 
  • Surface-enhanced Raman gene probe for HIV detection. 
  • Surfactant protein A is defective in abrogating inflammation in asthma. 
  • Surveillance for unexplained deaths and critical illnesses due to possibly infectious causes, United States, 1995-1998. 
  • Surveillance of carbapenem-resistant Klebsiella pneumoniae: tracking molecular epidemiology and outcomes through a regional network. 
  • Survey of familial glioma and role of germline p16INK4A/p14ARF and p53 mutation. 
  • Survey of the fragile X syndrome and the fragile X E syndrome in a special education needs population. 
  • Systematic review of the performance of HIV viral load technologies on plasma samples. 
  • T-Cell receptor Vbeta repertoire CDR3 length diversity differs within CD45RA and CD45RO T-cell subsets in healthy and human immunodeficiency virus-infected children. 
  • T296----M, a common mutation causing mild hemophilia B in the Amish and others: founder effect, variability in factor IX activity assays, and rapid carrier detection. 
  • TERC is not a major gene in human neural tube defects. 
  • TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. 
  • TP53 and RAS mutations in metachronous tumors from patients with cancer of the upper aerodigestive tract. 
  • Tagging ribozyme reaction sites to follow trans-splicing in mammalian cells. 
  • Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus. 
  • Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting. 
  • Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans. 
  • Targeting A20 decreases glioma stem cell survival and tumor growth. 
  • Targeting cancer stem cells through L1CAM suppresses glioma growth. 
  • Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis. 
  • Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation. 
  • TbetaRIII suppresses non-small cell lung cancer invasiveness and tumorigenicity. 
  • Telomere shortening in formerly abused and never abused women. 
  • Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers. 
  • Tenascin-C expression and distribution in cultured human chondrocytes and chondrosarcoma cells. 
  • Tetramerization and single-stranded DNA binding properties of native and mutated forms of murine mitochondrial single-stranded DNA-binding proteins. 
  • The 70-kDa heat shock cognate protein (Hsc73) gene is enhanced by ovarian hormones in the ventromedial hypothalamus. 
  • The A581G Mutation in the Gene Encoding Plasmodium falciparum Dihydropteroate Synthetase Reduces the Effectiveness of Sulfadoxine-Pyrimethamine Preventive Therapy in Malawian Pregnant Women. 
  • The ARMS2 A69S variant and bilateral advanced age-related macular degeneration. 
  • The Cryptococcus neoformans Rho-GDP dissociation inhibitor mediates intracellular survival and virulence. 
  • The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo. 
  • The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. 
  • The QPCR assay for analysis of mitochondrial DNA damage, repair, and relative copy number. 
  • The agent of Tyzzer's disease is a Clostridium species. 
  • The alpha 1C-adrenoceptor in human prostate: cloning, functional expression, and localization to specific prostatic cell types. 
  • The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer. 
  • The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development. 
  • The burden of hepatitis C virus infection in children: estimated direct medical costs over a 10-year period. 
  • The coactivator SRC-1 is an essential coordinator of hepatic glucose production. 
  • The cysP promoter of Salmonella typhimurium: characterization of two binding sites for CysB protein, studies of in vivo transcription initiation, and demonstration of the anti-inducer effects of thiosulfate. 
  • The differential expression of wound-inducible lipoxygenase genes in soybean leaves. 
  • The easiest children to reach are most likely to be infected with ocular Chlamydia trachomatis in trachoma endemic areas of Niger. 
  • The effect of irrigation solution at different temperatures on articular cartilage metabolism. 
  • The effects of BMP6 overexpression on adipose stem cell chondrogenesis: Interactions with dexamethasone and exogenous growth factors. 
  • The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study. 
  • The expression of platelet-derived growth-factor gene in Dupuytren contracture. 
  • The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response. 
  • The gene encoding the p60 subunit of chromatin assembly factor I (CAF1P60) maps to human chromosome 21q22.2, a region associated with some of the major features of Down syndrome. 
  • The genomic relationship between primary breast carcinomas and their nodal metastases. 
  • The geography of malaria genetics in the Democratic Republic of Congo: A complex and fragmented landscape. 
  • The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence. 
  • The in vivo balance between B cell clonal expansion and elimination is regulated by CD95 both on B cells and in their micro-environment. 
  • The incidence of ehrlichial and rickettsial infection in patients with unexplained fever and recent history of tick bite in central North Carolina. 
  • The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding. 
  • The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. 
  • The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus). 
  • The mechanism of autoantibody production in an autoimmune MRL/lpr mouse. 
  • The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis. 
  • The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4. 
  • The p53 signal transduction pathway is intact in human neuroblastoma despite cytoplasmic localization. 
  • The probability of HLA-C matching between patient and unrelated donor at the molecular level: estimations based on the linkage disequilibrium between DNA typed HLA-B and HLA-C alleles. 
  • The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase. 
  • The role of CCR5 and CCR2 polymorphisms in HIV-1 transmission and disease progression. 
  • The role of Mycoplasma and Ureaplasma in adverse pregnancy outcomes. 
  • The role of imaging studies and molecular markers for selecting candidates for radical prostatectomy. 
  • The role of innate immunity in acute allograft rejection after lung transplantation. 
  • The role of tandem mass spectrometry in the diagnosis of fatty acid oxidation disorders. 
  • The sentinel node in colorectal carcinoma. Mapping technique, pathologic assessment, and clinical relevance. 
  • The smallest membrane anchoring subunit (QPs3) of bovine heart mitochondrial succinate-ubiquinone reductase. Cloning, sequencing, topology, and Q-binding domain. 
  • The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selection. 
  • The ties that bind: genetic relatedness predicts the fission and fusion of social groups in wild African elephants. 
  • The tumor biology of melanoma nodal metastases. 
  • The use of a polymerase chain reaction as a diagnostic test for Rocky Mountain spotted fever. 
  • The vaginal introitus: a novel site for Chlamydia trachomatis testing in women. 
  • The value of fluorescence in situ hybridization and polymerase chain reaction in the diagnosis of B-cell non-Hodgkin lymphoma by fine-needle aspiration. 
  • Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline. 
  • Tissue-specific activation of cardiac angiotensin converting enzyme in experimental heart failure. 
  • Tissue-specific expression and regulation of the alternatively-spliced forms of lysyl hydroxylase 2 (LH2) in human kidney cells and skin fibroblasts. 
  • Toll-like receptor 3 polymorphism rs3775291 is not associated with choroidal neovascularization or polypoidal choroidal vasculopathy in Chinese subjects. 
  • Trans-activating rev protein of the human immunodeficiency virus 1 interacts directly and specifically with its target RNA. 
  • Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascade. 
  • Transcriptional regulation of the cholesteryl ester transfer protein gene by the orphan nuclear hormone receptor apolipoprotein AI regulatory protein-1. 
  • Transcriptional response to hypoxia in human tumors. 
  • Transplantation of enriched and purged peripheral blood progenitor cells from a single apheresis product in patients with non-Hodgkin's lymphoma. 
  • Treatment of chronic hepatitis C with interferon with or without ursodeoxycholic acid: a randomized prospective trial. 
  • Tropheryma whippelii DNA is rare in the intestinal mucosa of patients without other evidence of Whipple disease. 
  • Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein. 
  • Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases. 
  • Two mutational hotspots in the interleukin-2 receptor gamma chain gene causing human X-linked severe combined immunodeficiency. 
  • Two sensitive PCR-based methods for detection of hepatitis B virus variants associated with reduced susceptibility to lamivudine. 
  • Two tRNA gene clusters associated with rRNA operons rrnD and rrnE in Bacillus subtilis. 
  • U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts. 
  • UV absorption complicates PCR decontamination. 
  • Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. 
  • Uniparental mitochondrial transmission in sexual crosses in Cryptococcus neoformans. 
  • Unique oligonucleotide primers in PCR for identification of Cryptococcus neoformans. 
  • Unusual phenotypic expression of an XLRS1 mutation in X-linked juvenile retinoschisis. 
  • Unusual structure of the human immunodeficiency virus type 1 trans-activation response element. 
  • Urease as a virulence factor in experimental cryptococcosis. 
  • Use of the polymerase chain reaction for diagnosis of ocular toxoplasmosis. 
  • Use of the polymerase chain reaction in the diagnosis of unsuspected herpes simplex viral pneumonia: report of a case. 
  • Vaccination with mRNAs encoding tumor-associated antigens and granulocyte-macrophage colony-stimulating factor efficiently primes CTL responses, but is insufficient to overcome tolerance to a model tumor/self antigen. 
  • Validation of laboratory screening criteria for herpes simplex virus testing of cerebrospinal fluid. 
  • Variables affecting the T cell receptor V beta repertoire heterogeneity of T cells infiltrating human renal allografts. 
  • Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice. 
  • Vibratory loading decreases extracellular matrix and matrix metalloproteinase gene expression in rabbit annulus cells. 
  • Virus hunters: catching bugs in the field. 
  • Visualization of replication initiation and elongation in Drosophila. 
  • Visualizing mechanosensory endings of TrkC-expressing neurons in HS3ST-2-hPLAP mice. 
  • Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis. 
  • Vitamin D receptor polymorphisms and prostate cancer. 
  • Whipple's arthritis: direct detection of Tropheryma whippelii in synovial fluid and tissue. 
  • Whole exome sequencing of a dominant retinitis pigmentosa family identifies a novel deletion in PRPF31. 
  • Whole genome analysis: experimental access to all genome sequenced segments through larger-scale efficient oligonucleotide synthesis and PCR. 
  • X-linked genetic factors regulate hematopoietic stem-cell kinetics in females. 
  • X-linked high myopia associated with cone dysfunction. 
  • XRN1 stalling in the 5' UTR of Hepatitis C virus and Bovine Viral Diarrhea virus is associated with dysregulated host mRNA stability. 
  • Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. 
  • Zidovudine administered to women infected with human immunodeficiency virus type 1 and to their neonates reduces pediatric infection independent of an effect on levels of maternal virus. 
  • [Genetic structure of geographically different populations of candida albicans]. 
  • [PCR amplification and structural analysis of two paralogous rat estrogen sulfotransferase genes] 
  • cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. 
  • eNOS, a pressure-dependent regulator of intraocular pressure. 
  • lambda RNA internal standards quantify sensitivity and amplification efficiency of mammalian gene expression profiling. 
  • p53 gene alterations in human prostate carcinoma. 
  • p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia. 
• 

  Keywords of People

  • Alberts, Susan C., Robert F. Durden Professor of Biology, Marine Science and Conservation
  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Professor of Pediatrics, in the School of Medicine, Immunology
  • Carbrey, Jennifer Mehlman, Assistant Research Professor of Cell Biology, Cell Biology
  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
  • Erickson, Harold Paul, James B. Duke Professor of Medicine, Cell Biology
  • Grambow, Steven C., Assistant Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
  • Kelsoe, Garnett H., James B. Duke Professor of Immunology, Immunology
  • Lagoo, Anand Shreeram, Professor of Pathology, Pathology
  • Laskowitz, Daniel Todd, Professor of Neurology, Neurobiology
  • Liton, Paloma Borrajo, Associate Professor of Ophthalmology, Pathology
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • MacFall, James R., Adjunct Professor in the Department of Radiology, Radiology
  • McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Pharmacology & Cancer Biology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Moorman, Patricia Gripka, Professor in Community and Family Medicine, Duke Cancer Institute
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Noor, Mohamed A. F., Professor of Biology, Biology
  • Pang, Herbert, Adjunct Assistant Professor in the Department of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Premont, Richard Thomas, Associate Professor in Medicine, Medicine, Gastroenterology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology
  • Taylor, Gregory Alan, Associate Professor in Medicine, Immunology
  • Tsalik, Ephraim, Associate Professor of Medicine, Molecular Genetics and Microbiology
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Professor of Experimental Surgery, in the School of Medicine, Immunology
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
  • Yan, Hai, Henry S. Friedman Professor of Neuro-Oncology in the School of Medicine, Pathology