Holoprosencephaly

• 

  Subject Areas on Research

  • BMP antagonism protects Nodal signaling in the gastrula to promote the tissue interactions underlying mammalian forebrain and craniofacial patterning. 
  • Chordin and noggin promote organizing centers of forebrain development in the mouse. 
  • Congenital nasal pyriform aperture stenosis in the monozygotic twin of a child with holoprosencephaly. 
  • Non-genetic risk factors for holoprosencephaly. 
  • Roles of bone morphogenetic protein signaling and its antagonism in holoprosencephaly.