Free Radical Scavengers
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Subject Areas on Research
- A comparative study of antioxidative activities of cell-wall polysaccharides.
- An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation.
- Antioxidant defense mechanisms in cultured pleural mesothelial cells.
- Antioxidants suppress mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE).
- Brain temperature alters hydroxyl radical production during cerebral ischemia/reperfusion in rats.
- Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants.
- Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid.
- Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae.
- Cold-induced brain edema in mice. Involvement of extracellular superoxide dismutase and nitric oxide.
- Dependence of the cyanobacterium Prochlorococcus on hydrogen peroxide scavenging microbes for growth at the ocean's surface.
- Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.
- Different roles of radical scavengers--ascorbate and urate in the cerebrospinal fluid of amyotrophic lateral sclerosis patients.
- Duodenal cytochrome b: a novel ferrireductase in airway epithelial cells.
- Effect of U74006F (Tirilazad Mesylate) in rabbit eyes after argon laser trabeculoplasty.
- Effects of genotype and environment on the antioxidant properties of hard winter wheat bran.
- Genes upregulated in the human trabecular meshwork in response to elevated intraocular pressure.
- Haptoglobin alters oxygenation and oxidation of hemoglobin and decreases propagation of peroxide-induced oxidative reactions.
- Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart.
- Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier.
- In vivo assessment of free radical activity during shock wave lithotripsy using a microdialysis system: the renoprotective action of allopurinol.
- Increased tonic activation of rat forebrain 5-HT(1A) receptors by lithium addition to antidepressant treatments.
- Involvement of reactive oxygen species in the electrochemical inhibition of barnacle (Amphibalanus amphitrite) settlement.
- Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis.
- L-N-Acetylcysteine treatment is associated with improved hearing outcome in sudden idiopathic sensorineural hearing loss.
- LKB1 reduces ROS-mediated cell damage via activation of p38.
- Limiting impairment of muscle function following ischemia and reperfusion in rabbits.
- Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.
- Location-dependent artifact for no measurement using multiwell plates.
- Manganese porphyrins and related compounds as mimics of superoxide dismutase.
- Manganese-porphyrin reactions with lipids and lipoproteins.
- Metalloporphyrins are potent inhibitors of lipid peroxidation.
- Mitochondria in sporadic amyotrophic lateral sclerosis.
- Mitochondrial Quality Control as a Therapeutic Target.
- Modulation of ultraviolet light-induced epidermal damage: beneficial effects of tocopherol.
- Neuroprotective effect of curcumin in an experimental rat model of subarachnoid hemorrhage.
- New series of aryloxypropanolamines with both human beta(3)-adrenoceptor agonistic activity and free radical scavenging properties.
- Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis.
- Predicted effects of nitric oxide and superoxide on the vasoactivity of the afferent arteriole.
- Pulmonary vasoconstriction by serotonin is inhibited by S-nitrosoglutathione.
- Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.
- Pure manganese(III) 5,10,15,20-tetrakis(4-benzoic acid)porphyrin (MnTBAP) is not a superoxide dismutase mimic in aqueous systems: a case of structure-activity relationship as a watchdog mechanism in experimental therapeutics and biology.
- Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes.
- RETRACTED: NAD(P)H:quinone oxidoreductase 1 protects lungs from oxidant-induced emphysema in mice.
- Randomized trial of acetylcysteine in idiopathic pulmonary fibrosis.
- Rotational isomers of N-alkylpyridylporphyrins and their metal complexes. HPLC separation, (1)H NMR and X-ray structural characterization, electrochemistry, and catalysis of O(2)(.-) disproportionation.
- Synthetic surfactant scavenges oxidants and protects against hyperoxic lung injury.
- TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death.
- The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic.
- The role of allopurinol and deferoxamine in preventing pressure ulcers in pigs.
- Xanthine oxidase inhibition for hyperuricemic heart failure patients: design and rationale of the EXACT-HF study.
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Keywords of People
- Preminger, Glenn Michael, James F. Glenn, M.D. Professor of Urology, Surgery
- Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology