Receptors, Interleukin-3

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  Subject Areas on Research

  • Absolute values of dendritic cell subsets in bone marrow, cord blood, and peripheral blood enumerated by a novel method. 
  • Enhanced expression of interleukin-3 and granulocyte-macrophage colony-stimulating factor receptor subunits in murine hematopoietic cells stimulated with hematopoietic growth factors. 
  • Erythropoietin receptor signals both proliferation and erythroid-specific differentiation. 
  • Interleukin-3-induced activation of the JAK/STAT pathway is prolonged by proteasome inhibitors. 
  • JAK2 is required for induction of the murine DUB-1 gene. 
  • Multiple transcription start sites and 5' alternate splicing of murine IL-3 receptor beta-chain transcripts. 
  • The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein. 
  • The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells. 
  • The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.