S Phase
-
Subject Areas on Research
- A CDC6 protein-binding peptide selected using a bacterial two-hybrid-like system is a cell cycle inhibitor.
- A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2.
- A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition.
- A statistic for comparing two correlated markers which are prognostic for time to an event.
- AKT1 mediates bypass of the G1/S checkpoint after genotoxic stress in normal human cells.
- ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway.
- All aboard the cyclin train: subcellular trafficking of cyclins and their CDK partners.
- BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation.
- Bifunctional DNA alkylator 1,3-bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway.
- Calcineurin regulates cyclin D1 accumulation in growth-stimulated fibroblasts.
- Cell cycle dependence of group VIA calcium-independent phospholipase A2 activity.
- Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae.
- Cell cycle-dependent expression of thyroid hormone receptor-beta is a mechanism for variable hormone sensitivity.
- Cell cycle. Checking two steps.
- Cell-Cycle-Dependent Chromatin Dynamics at Replication Origins.
- Centromere identity in Drosophila is not determined in vivo by replication timing.
- Chromatin association of rad17 is required for an ataxia telangiectasia and rad-related kinase-mediated S-phase checkpoint in response to low-dose ultraviolet radiation.
- Chromium(VI) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle.
- Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways.
- Defining origins of replication in mammalian cells.
- Defining the replication program through the chromatin landscape.
- Definition of a FoxA1 Cistrome that is crucial for G1 to S-phase cell-cycle transit in castration-resistant prostate cancer.
- Differential susceptibility of yeast S and M phase CDK complexes to inhibitory tyrosine phosphorylation.
- Dissociation of radiation-induced phosphorylation of replication protein A from the S-phase checkpoint.
- Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6.
- Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells.
- Drosophila Symplekin localizes dynamically to the histone locus body and tricellular junctions.
- Drosophila homologue of the Rothmund-Thomson syndrome gene: essential function in DNA replication during development.
- E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.
- Expression of a constitutively active Ca2+/calmodulin-dependent kinase in Aspergillus nidulans spores prevents germination and entry into the cell cycle.
- Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression.
- FANCD2 monoubiquitination and activation by hexavalent chromium [Cr(VI)] exposure: activation is not required for repair of Cr(VI)-induced DSBs.
- Flow cytometric DNA analysis of excised breast lesions: use of fresh tissue needle aspirates obtained under guidance with mammography of the specimen.
- Flow cytometric and quantitative histological parameters to predict occult disease in clinical stage I nonseminomatous testicular germ cell tumors.
- Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX.
- Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation.
- Global control of cell-cycle transcription by coupled CDK and network oscillators.
- Human Rad9 is required for the activation of S-phase checkpoint and the maintenance of chromosomal stability.
- In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability.
- In vitro and in vivo antitumor effect of the anti-CD26 monoclonal antibody 1F7 on human CD30+ anaplastic large cell T-cell lymphoma Karpas 299.
- Inhibition of calcium-independent phospholipase A2 suppresses proliferation and tumorigenicity of ovarian carcinoma cells.
- Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function.
- Inositol pyrophosphates modulate S phase progression after pheromone-induced arrest in Saccharomyces cerevisiae.
- Interaction of FANCD2 and NBS1 in the DNA damage response.
- Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.
- Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.
- Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage.
- Loss of G(1)/S checkpoint in human immunodeficiency virus type 1-infected cells is associated with a lack of cyclin-dependent kinase inhibitor p21/Waf1.
- Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila.
- Multiple signaling pathways involving ATM.
- Myc requires distinct E2F activities to induce S phase and apoptosis.
- Neutrophil elastase inhibition of cell cycle progression in airway epithelial cells in vitro is mediated by p27kip1.
- Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation.
- Nuclear inositol signaling: a structural and functional approach.
- Nuclear phosphatidylinositols decrease during S-phase of the cell cycle in HeLa cells.
- PINA is essential for growth and positively influences NIMA function in Aspergillus nidulans.
- Parametric modeling of cellular state transitions as measured with flow cytometry.
- Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation.
- Physiological electric fields control the G1/S phase cell cycle checkpoint to inhibit endothelial cell proliferation.
- Proliferation of Double-Strand Break-Resistant Polyploid Cells Requires Drosophila FANCD2.
- Protein kinase CK2 phosphorylates the cell cycle regulatory protein Geminin.
- Protein phosphatase 5 is required for ATR-mediated checkpoint activation.
- Randomized trial of cyclophosphamide, methotrexate, and 5-fluorouracil with or without estrogenic recruitment in women with metastatic breast cancer.
- Regulation of Kv1 subunit expression in oligodendrocyte progenitor cells and their role in G1/S phase progression of the cell cycle.
- Replication control of autonomously replicating human sequences.
- Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation.
- Resveratrol arrests the cell division cycle at S/G2 phase transition.
- Senescent fibroblasts resist apoptosis by downregulating caspase-3.
- Skp2 regulates Myc protein stability and activity.
- Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells.
- Temporal profile of replication of human chromosomes.
- The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae.
- The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells.
- The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability.
- The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells.
- Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation.
- Waves of Cdk1 Activity in S Phase Synchronize the Cell Cycle in Drosophila Embryos.
- When the checkpoints have gone: insights into Cdc25 functional activation.
-
Keywords of People
- Hartemink, Alexander J., Professor in the Department of Computer Science, Biology