N-Methylaspartate
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Subject Areas on Research
- "Silent" NMDA Synapses Enhance Motion Sensitivity in a Mature Retinal Circuit.
- A grease-gap method for studying the excitatory amino acid pharmacology of CA1 hippocampal pyramidal cells.
- A radiohistochemical measure of [3H]TCP binding to the activated NMDA-receptor-gated ion channel in rat brain.
- Activated cAMP-response element-binding protein regulates neuronal expression of presenilin-1.
- Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture.
- Apolipoprotein E protects against NMDA excitotoxicity.
- Apoptosis is not enhanced in primary mixed neuronal/glial cultures protected by isoflurane against N-methyl-D-aspartate excitotoxicity.
- Arc/Arg3.1 translation is controlled by convergent N-methyl-D-aspartate and Gs-coupled receptor signaling pathways.
- Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder.
- Biochemical evidence for enhanced sensitivity to N-methyl-D-aspartate in the hippocampal formation of kindled rats.
- Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission.
- Cellular determinants of reduced adaptability of the aging brain: neurotransmitter utilization and cell signaling responses after MDMA lesions.
- Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro.
- Characterization of neuronal/glial differentiation of murine adipose-derived adult stromal cells.
- Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus.
- Comparison of the potency of competitive NMDA antagonists against the neurotoxicity of glutamate and NMDA.
- Contributions of striatal subregions to place and response learning.
- Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers.
- Dementia assessment and management.
- Dissociable roles for the basolateral amygdala and orbitofrontal cortex in decision-making under risk of punishment.
- Effect of halothane in cortical cell cultures exposed to N-methyl-D-aspartate.
- Effects of volatile anesthetics on N-methyl-D-aspartate excitotoxicity in primary rat neuronal-glial cultures.
- Ethanol and magnesium ions inhibit N-methyl-D-aspartate-mediated synaptic potentials in an interactive manner.
- Ethanol inhibition of NMDA mediated depolarizations is increased in the presence of Mg2+.
- Excitatory synaptic potentials in kainic acid-denervated rat CA1 pyramidal neurons.
- GABAB-Receptor-mediated currents in interneurons of the dentate-hilus border.
- GABAB-receptor-mediated inhibition of the N-methyl-D-aspartate component of synaptic transmission in the rat hippocampus.
- Glycine regulation of the N-methyl-D-aspartate receptor-gated ion channel in hippocampal membranes.
- In Vivo Evaluation of White Matter Integrity and Anterograde Transport in Visual System After Excitotoxic Retinal Injury With Multimodal MRI and OCT.
- Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation.
- Inhibition of muscarinic-coupled phosphoinositide hydrolysis by N-methyl-D-aspartate is dependent on depolarization via channel activation.
- Involvement of cAMP-dependent protein kinase in mu-opioid modulation of NMDA-mediated synaptic currents.
- Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.
- Ionotropic glutamate receptor subtypes activate c-fos transcription by distinct calcium-requiring intracellular signaling pathways.
- Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect?
- Kindling enhances sensitivity of CA3 hippocampal pyramidal cells to NMDA.
- Kindling, prenatal exposure to ethanol and postnatal development selectively alter responses of hippocampal pyramidal cells to NMDA.
- Mechanism of detection of acute cerebral ischemia in rats by diffusion-weighted magnetic resonance microscopy.
- Method of lesioning brainstem determines seizure probability.
- Multifocal electroretinogram in rhodopsin P347L transgenic pigs.
- N-methyl-D-aspartate receptor regulation of uncompetitive antagonist binding in rat brain membranes: kinetic analysis.
- NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro.
- NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression.
- NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model.
- NMDA receptor-mediated depolarizing action of proline on CA1 pyramidal cells.
- NMDA-Receptor-dependent synaptic activation of voltage-dependent calcium channels in basolateral amygdala.
- NMDA-induced apoptosis in mixed neuronal/glial cortical cell cultures: the effects of isoflurane and dizocilpine.
- Neuroprotection by N-methyl-D-aspartate antagonists in focal cerebral ischemia is dependent on continued maintenance dosing.
- Neuroprotective effects of creatine administration against NMDA and malonate toxicity.
- Nitric oxide in glutamate-induced compound action potential threshold shifts.
- Pharmacologically defined components of the normal porcine multifocal ERG.
- Polyamines antagonize N-methyl-D-aspartate-evoked depolarizations, but reduce Mg2+ block.
- Postischemic synaptic excitation and N-methyl-D-aspartate receptor activation in gerbils.
- Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation.
- Prenatal exposure to ethanol decreases the sensitivity of the adult rat hippocampus to N-methyl-D-aspartate.
- Proconvulsant and anticonvulsant properties of ethanol: studies of electrographic seizures in vitro.
- Proline-induced potentiation of glutamate transmission.
- Protective effect of apolipoprotein E-mimetic peptides on N-methyl-D-aspartate excitotoxicity in primary rat neuronal-glial cell cultures.
- Recurrent mossy fiber pathway in rat dentate gyrus: synaptic currents evoked in presence and absence of seizure-induced growth.
- Redox regulation of neuronal migration in a Down Syndrome model.
- Requirement for superoxide in excitotoxic cell death.
- Role of the GLT-1 subtype of glutamate transporter in glutamate homeostasis: the GLT-1-preferring inhibitor WAY-855 produces marginal neurotoxicity in the rat hippocampus.
- Role of the substantia nigra in the kindling model of limbic epilepsy.
- Slow NMDA-EPSCs at synapses critical for song development are not required for song learning in zebra finches.
- Stimulation of substantia nigra pars reticulata enhances dentate granule cell excitability.
- TCP binding: a tool for studying NMDA receptor-mediated neurotransmission in kindling.
- The G72/G30 gene complex and cognitive abnormalities in schizophrenia.
- The NMDA receptor antagonist 2-amino-5-phosphonovalerate blocks stimulus train-induced epileptogenesis but not epileptiform bursting in the rat hippocampal slice.
- The role of substantia nigra in the development of kindling: pharmacologic and lesion studies.
- The role of the dorsomedial striatum in instrumental conditioning.
- Two affinity states of N-methyl-D-aspartate recognition sites: modulation by cations.
- Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel.
- β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain.