AIDS-Associated Nephropathy

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  Subject Areas on Research

  • APOL1 variants in HIV-associated nephropathy: just one piece of the puzzle. 
  • APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy. 
  • APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy. 
  • Antiretroviral medications: adverse effects on the kidney. 
  • Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy. 
  • Editorial comment: renal insufficiency in HIV-infected patients may not always be HIVAN. 
  • FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy. 
  • HIV and the Kidney: From HIV-Associated Nephropathy to Reservoir. 
  • HIV and the aging kidney. 
  • HIV at 40: kidney disease in HIV treatment, prevention, and cure. 
  • HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response. 
  • HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes. 
  • HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells. 
  • HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells. 
  • HIV-1 and HIV-Associated Nephropathy 25 Years Later. 
  • HIV-1 induces renal epithelial dedifferentiation in a transgenic model of HIV-associated nephropathy. 
  • HIV-1 infection initiates an inflammatory cascade in human renal tubular epithelial cells. 
  • HIV-1 infection of renal epithelial cells: 30 years of evidence from transgenic animal models, human studies and in vitro experiments. 
  • HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. 
  • HIV-associated nephropathy in the era of antiretroviral therapy. 
  • HIV-associated nephropathy is a late, not early, manifestation of HIV-1 infection. 
  • HIV-associated nephropathy: a case study in race and genetics. 
  • HIV-associated nephropathy: clinical presentation, pathology, and epidemiology in the era of antiretroviral therapy. 
  • Highly active antiretroviral therapy and the epidemic of HIV+ end-stage renal disease. 
  • Impact of early versus deferred antiretroviral therapy on estimated glomerular filtration rate in HIV-positive individuals in the START trial. 
  • Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. 
  • Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression. 
  • Pharmacotherapy for human immunodeficiency virus-associated nephropathy. 
  • Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy. 
  • Podocyte cell cycle regulation and proliferation in collapsing glomerulopathies. 
  • Potential role for G-protein coupled receptors in HIV-associated nephropathy. 
  • Proliferation of HIV-infected renal epithelial cells following virus acquisition from infected macrophages. 
  • Protease inhibitors are associated with a slowed progression of HIV-related renal diseases. 
  • Recent progress in HIV-associated nephropathy. 
  • Reduction of Stat3 activity attenuates HIV-induced kidney injury. 
  • Regional and Racial Disparities in HIV-Related Kidney Disease. 
  • Relapse of HIV-associated nephropathy after discontinuing highly active antiretroviral therapy. 
  • Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease. 
  • Taking HAART in HIVAN: will protease inhibitor sparing regimens alter renal outcome? 
  • The changing epidemiology of HIV-related chronic kidney disease in the era of antiretroviral therapy. 
  • The clinical epidemiology and course of the spectrum of renal diseases associated with HIV infection. 
  • The dysregulated podocyte phenotype: a novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy. 
  • The homophilic adhesion molecule sidekick-1 contributes to augmented podocyte aggregation in HIV-associated nephropathy. 
  • The kidney in HIV infection: beyond HIV-associated nephropathy. 
  • The spectrum of kidney biopsy findings in HIV-infected patients in the modern era. 
  • The spectrum of kidney disease in patients with AIDS in the era of antiretroviral therapy. 
  • The uncertain significance of anti-glomerular basement membrane antibody among HIV-infected persons with kidney disease. 
  • Tubular-specific expression of HIV protein Vpr leads to severe tubulointerstitial damage accompanied by progressive fibrosis and cystic development. 
  • Urinary NGAL marks cystic disease in HIV-associated nephropathy. 
  • Urine processing impacts uric acid level in HIV-infected adults: implications for diagnosing tenofovir-associated proximal tubulopathy. 
  • Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells.