NF-kappa B

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  Subject Areas on Research

  • ^* CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments. 
  • A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation. 
  • A detrimental role of RelB in mature oligodendrocytes during experimental acute encephalomyelitis. 
  • A loss-of-function RNA interference screen for molecular targets in cancer. 
  • A new prostate cancer therapeutic approach: combination of androgen ablation with COX-2 inhibitor. 
  • A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells. 
  • A novel immunomodulatory protein from Poria cocos induces Toll-like receptor 4-dependent activation within mouse peritoneal macrophages. 
  • A nuclear factor-kappaB inhibitor BAY11-7082 inhibits interactions between human endothelial cells, T cells, and monocytes. 
  • A pathway of neuronal apoptosis induced by hypoxia/reoxygenation: roles of nuclear factor-kappaB and Bcl-2. 
  • A phase II study of isoflavones, erlotinib, and gemcitabine in advanced pancreatic cancer. 
  • A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation. 
  • A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with Staphylococcal aureus sepsis. 
  • A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation. 
  • A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis. 
  • A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis. 
  • A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia. 
  • Aberrant NF-kappaB activity is critical in focal necrosis formation of human glioblastoma by regulation of the expression of tissue factor. 
  • Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. 
  • Activation and cross-talk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78. 
  • Activation of Nrf2 Pathway Contributes to Neuroprotection by the Dietary Flavonoid Tiliroside. 
  • Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth. 
  • Activation of the 9E3/cCAF chemokine by phorbol esters occurs via multiple signal transduction pathways that converge to MEK1/ERK2 and activate the Elk1 transcription factor. 
  • Activation of transcription factors activator protein-1 and nuclear factor-kappaB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. 
  • Activation of vascular smooth muscle cells by TNF and PDGF: overlapping and complementary signal transduction mechanisms. 
  • Advanced glycation end-product of low density lipoprotein activates the toll-like 4 receptor pathway implications for diabetic atherosclerosis. 
  • Agathisflavone isolated from Anacardium occidentale suppresses SIRT1-mediated neuroinflammation in BV2 microglia and neurotoxicity in APPSwe-transfected SH-SY5Y cells. 
  • Alcohol and cytokine-inducible transcription factors. 
  • Aldosterone-induced activation of signaling pathways requires activity of angiotensin type 1a receptors. 
  • Alpha7 cholinergic-agonist prevents systemic inflammation and improves survival during resuscitation. 
  • Alteration of NF-kappa B p50 DNA binding kinetics by S-nitrosylation. 
  • An essential role for c-FLIP in the efficient development of mature T lymphocytes. 
  • Analysis of Epstein-Barr virus-regulated host gene expression changes through primary B-cell outgrowth reveals delayed kinetics of latent membrane protein 1-mediated NF-κB activation. 
  • Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial fluid immune cells. 
  • Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia. 
  • Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut. 
  • Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations. 
  • Antimalarial Drug Artemether Inhibits Neuroinflammation in BV2 Microglia Through Nrf2-Dependent Mechanisms. 
  • Antitumor activity of epidermal growth factor receptor-related protein is mediated by inactivation of ErbB receptors and nuclear factor-kappaB in pancreatic cancer. 
  • Apoptosis and NF-kappa B: the FADD connection. 
  • Aspirin inhibits tumor necrosis factoralpha gene expression in murine tissue macrophages. 
  • Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer. 
  • Assessment of CD37 B-cell antigen and cell of origin significantly improves risk prediction in diffuse large B-cell lymphoma. 
  • Ataxia-telangiectasia group D complementing gene (ATDC) promotes lung cancer cell proliferation by activating NF-κB pathway. 
  • Atherosclerosis: a cancer of the blood vessels? 
  • Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide. 
  • Beryllium fluoride-induced cell proliferation: a process requiring P21(ras)-dependent activated signal transduction and NF-kappaB-dependent gene regulation. 
  • Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms. 
  • Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. 
  • Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder. 
  • C-reactive protein activates the nuclear factor-kappaB signal transduction pathway in saphenous vein endothelial cells: implications for atherosclerosis and restenosis. 
  • CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC. 
  • CD30 activates both the canonical and alternative NF-kappaB pathways in anaplastic large cell lymphoma cells. 
  • CD30-activation-mediated growth inhibition of anaplastic large-cell lymphoma cell lines: apoptosis or cell-cycle arrest? 
  • CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival. 
  • CD36 initiates the secretory phenotype during the establishment of cellular senescence. 
  • COMMD proteins, a novel family of structural and functional homologs of MURR1. 
  • CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues. 
  • Cadmium-induced DNA synthesis and cell proliferation in macrophages: the role of intracellular calcium and signal transduction mechanisms. 
  • Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4. 
  • Canonical transient receptor potential 3 channels activate NF-κB to mediate allergic airway disease via PKC-α/IκB-α and calcineurin/IκB-β pathways. 
  • Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B. 
  • Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death. 
  • Caspase-8-mediated apoptosis in human RPE cells. 
  • Characterization of COMMD protein-protein interactions in NF-kappaB signalling. 
  • Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase. 
  • Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer. 
  • Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules. 
  • Chronic ethanol exposure potentiates lipopolysaccharide liver injury despite inhibiting Jun N-terminal kinase and caspase 3 activation. 
  • Clinical implications of phosphorylated STAT3 expression in De Novo diffuse large B-cell lymphoma. 
  • Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65. 
  • Co-regulation of nuclear respiratory factor-1 by NFkappaB and CREB links LPS-induced inflammation to mitochondrial biogenesis. 
  • Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion. 
  • Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells. 
  • Commensal microbiota stimulate systemic neutrophil migration through induction of serum amyloid A. 
  • Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1. 
  • Context-dependent activation kinetics elicited by soluble versus outer membrane vesicle-associated heat-labile enterotoxin. 
  • Cooperation between transcription factor AP-1 and NF-kappaB in the induction of interleukin-8 in human pancreatic adenocarcinoma cells by hypoxia. 
  • Copper is a potent inhibitor of both the canonical and non-canonical NFκB pathways. 
  • Cowpox virus and other members of the orthopoxvirus genus interfere with the regulation of NF-kappaB activation. 
  • Cowpox virus inhibits human dendritic cell immune function by nonlethal, nonproductive infection. 
  • Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines. 
  • Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells. 
  • Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo. 
  • Cyclic AMP modulates the functional plasticity of immature dendritic cells by inhibiting Src-like kinases through protein kinase A-mediated signaling. 
  • Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3. 
  • Cytokine induction of nuclear factor kappa B in cycling and growth-arrested cells. Evidence for cell cycle-independent activation. 
  • DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifs. 
  • Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells. 
  • Differential effects of nitric oxide-mediated S-nitrosylation on p50 and c-jun DNA binding. 
  • Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-kappa B subunits in endothelial and epithelial cells. 
  • Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3). 
  • Direct-contact co-culture between smooth muscle and endothelial cells inhibits TNF-alpha-mediated endothelial cell activation. 
  • Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation. 
  • Distinction between differentiation, cell cycle, and apoptosis signals in PC12 cells by the nerve growth factor mutant delta9/13, which is selective for the p75 neurotrophin receptor. 
  • Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells. 
  • Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin. 
  • Diverse functions within the IAP family. 
  • Dopaminergic Control of Inflammation and Glycemia in Sepsis and Diabetes. 
  • Down-regulation of platelet-derived growth factor-D inhibits cell growth and angiogenesis through inactivation of Notch-1 and nuclear factor-kappaB signaling. 
  • Dying for NF-kappaB? Control of cell death by transcriptional regulation of the apoptotic machinery. 
  • Dying glioma cells establish a proangiogenic microenvironment through a caspase 3 dependent mechanism. 
  • EBV latent membrane protein 2A induces autoreactive B cell activation and TLR hypersensitivity. 
  • EBV-positive diffuse large B-cell lymphoma of the elderly is an aggressive post-germinal center B-cell neoplasm characterized by prominent nuclear factor-kB activation. 
  • ELKS1 controls mast cell degranulation by regulating the transcription of Stxbp2 and Syntaxin 4 via Kdm2b stabilization. 
  • Effect of NF-kappa B inhibition on TNF-alpha-induced apoptosis in human RPE cells. 
  • Effect of ethanol on tumor necrosis factor signaling during liver regeneration. 
  • Effect of low-fat diets on plasma levels of NF-κB-regulated inflammatory cytokines and angiogenic factors in men with prostate cancer. 
  • Effect of mutant IkappaB on cytokine-induced activation of NF-kappaB in cultured human RPE cells. 
  • Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression. 
  • Effects of TNFalpha on expression of ICAM-1 in human airway epithelial cells in vitro: oxidant-mediated pathways and transcription factors. 
  • Effects of cartilage impact with and without fracture on chondrocyte viability and the release of inflammatory markers. 
  • Effects of chronic ethanol consumption on cytokine regulation of liver regeneration. 
  • Effects of physiological and synthetic IAP antagonism on c-IAP-dependent signaling. 
  • Effects of the NIK aly mutation on NF-kappaB activation by the Epstein-Barr virus latent infection membrane protein, lymphotoxin beta receptor, and CD40. 
  • Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts. 
  • Elevated circulating tissue inhibitor of metalloproteinase 1 (TIMP-1) levels are associated with neuroendocrine differentiation in castration resistant prostate cancer. 
  • Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression. 
  • Endotoxin-mediated S-nitrosylation of p50 alters NF-kappa B-dependent gene transcription in ANA-1 murine macrophages. 
  • Endotoxin-mediated nitric oxide synthesis inhibits IL-1beta gene transcription in ANA-1 murine macrophages. 
  • Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. 
  • Epidermal growth factor receptor-related protein inhibits cell growth and invasion in pancreatic cancer. 
  • Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation. 
  • Epstein-Barr virus latent membrane protein 1 activation of NF-kappaB through IRAK1 and TRAF6. 
  • Escaping G1 restraints on neoplasia--Cdk4 regulation by Ras and NF-kappa B. 
  • Ethyl pyruvate improves survival in awake hemorrhage. 
  • Ethyl pyruvate prevents inflammatory responses and organ damage during resuscitation in porcine hemorrhage. 
  • Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. 
  • Evaluation of NF-κB subunit expression and signaling pathway activation demonstrates that p52 expression confers better outcome in germinal center B-cell-like diffuse large B-cell lymphoma in association with CD30 and BCL2 functions. 
  • Exhaled nitric oxide (NO), NO synthase activity, and regulation of nuclear factor (NF)-kappaB. 
  • Extracellular signal-regulated kinase regulation of tumor necrosis factor-alpha mRNA nucleocytoplasmic transport requires TAP-NxT1 binding and the AU-rich element. 
  • Extrinsic coagulation blockade attenuates lung injury and proinflammatory cytokine release after intratracheal lipopolysaccharide. 
  • Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-κB-dependent pathways. 
  • Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation. 
  • First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway. 
  • Focal adhesion kinase mediates the interferon-gamma-inducible GTPase-induced phosphatidylinositol 3-kinase/Akt survival pathway and further initiates a positive feedback loop of NF-kappaB activation. 
  • Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. 
  • Function of nuclear factor kappaB in pancreatic cancer metastasis. 
  • Functional Toll-like receptor 4 mutations modulate the response to fibrinogen. 
  • G protein-coupled receptor kinase-5 attenuates atherosclerosis by regulating receptor tyrosine kinases and 7-transmembrane receptors. 
  • GRP94/gp96 elicits ERK activation in murine macrophages. A role for endotoxin contamination in NF-kappa B activation and nitric oxide production. 
  • Gene profiling of canine B-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human DLBCL. 
  • Glutamine attenuates inflammation and NF-kappaB activation via Cullin-1 deneddylation. 
  • Glutamine therapy improves outcome of in vitro and in vivo experimental colitis models. 
  • Glutamine's protection against sepsis and lung injury is dependent on heat shock protein 70 expression. 
  • Glutathione peroxidase-deficient smooth muscle cells cause paracrine activation of normal smooth muscle cells via cyclophilin A. 
  • Hemochromatosis drives acute lethal intestinal responses to hyperyersiniabactin-producing Yersinia pseudotuberculosis. 
  • Hemoglobin-induced endothelial cell permeability is controlled, in part, via a myeloid differentiation primary response gene-88-dependent signaling mechanism. 
  • Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance. 
  • Holding the Inflammatory System in Check: TLRs and NLRs. 
  • Human RPE expression of cell survival factors. 
  • Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation. 
  • Hypoxia inducible factor 1alpha signaling in fractionated radiation-induced lung injury: role of oxidative stress and tissue hypoxia. 
  • IFI16-STING-NF-κB signaling controls exogenous mitochondrion-induced endothelial activation. 
  • IFN-α inhibits telomerase in human CD8⁺ T cells by both hTERT downregulation and induction of p38 MAPK signaling. 
  • IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3. 
  • IL-1 and TNFα Contribute to the Inflammatory Niche to Enhance Alveolar Regeneration. 
  • IL-17 Production of Neutrophils Enhances Antibacteria Ability but Promotes Arthritis Development During Mycobacterium tuberculosis Infection. 
  • IRF-1 inhibits NF-κB activity, suppresses TRAF2 and cIAP1 and induces breast cancer cell specific growth inhibition. 
  • Identification of novel mediators of NF-kappaB through genome-wide survey of monocyte adherence-induced genes. 
  • Identifying new small molecule anti-invasive compounds for glioma treatment. 
  • In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer. 
  • In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis. 
  • In vivo luminescent imaging of NF-κB activity and NF-κB-related serum cytokine levels predict pain sensitivities in a rodent model of peripheral neuropathy. 
  • Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation. 
  • Induction of Autophagy and Activation of SIRT-1 Deacetylation Mechanisms Mediate Neuroprotection by the Pomegranate Metabolite Urolithin A in BV2 Microglia and Differentiated 3D Human Neural Progenitor Cells. 
  • Induction of CD56 and TCR-independent activation of T cells with aging. 
  • Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment. 
  • Induction of mitogenic signalling in the 1LN prostate cell line on exposure to submicromolar concentrations of cadmium+. 
  • Induction of nuclear factor kappaB by the CD30 receptor is mediated by TRAF1 and TRAF2. 
  • Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies. 
  • Inhibition of Blood-Brain Barrier Disruption by an Apolipoprotein E-Mimetic Peptide Ameliorates Early Brain Injury in Experimental Subarachnoid Hemorrhage. 
  • Inhibition of Methicillin-resistant Staphylococcus aureus-induced cytokines mRNA production in human bone marrow derived mesenchymal stem cells by 1,25-dihydroxyvitamin D3. 
  • Inhibition of NF-kappa B and oxidative pathways in human dendritic cells by antioxidative vitamins generates regulatory T cells. 
  • Inhibition of NF-kappa B by S-nitrosylation. 
  • Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. 
  • Inhibition of neuroinflammation by thymoquinone requires activation of Nrf2/ARE signalling. 
  • Inhibition of neuroinflammation in BV2 microglia by the biflavonoid kolaviron is dependent on the Nrf2/ARE antioxidant protective mechanism. 
  • Inhibition of nuclear factor-kappaB-mediated adhesion molecule expression in human endothelial cells. 
  • Inhibition of the transcriptional activator protein nuclear factor kappaB prevents hemodynamic instability associated with the whole-body inflammatory response syndrome. 
  • Innate immune signaling through differential RIPK1 expression promote tumor progression in head and neck squamous cell carcinoma. 
  • Integrated systems approach defines the antiviral pathways conferring protection by the RV144 HIV vaccine. 
  • Integrative genomic approaches identify IKBKE as a breast cancer oncogene. 
  • Interleukin-1beta elevates cyclooxygenase-2 protein level and enzyme activity via increasing its mRNA stability in human endometrial stromal cells: an effect mediated by extracellularly regulated kinases 1 and 2. 
  • Isoleucine 44 Hydrophobic Patch Controls Toxicity of Unanchored, Linear Ubiquitin Chains through NF-κB Signaling. 
  • JAK2 inhibition prevents innate immune responses and rescues animals from sepsis. 
  • KIND1 Loss Sensitizes Keratinocytes to UV-Induced Inflammatory Response and DNA Damage. 
  • Kernel canonical correlation analysis for assessing gene-gene interactions and application to ovarian cancer. 
  • Kruppel-like factor 15 is critical for vascular inflammation. 
  • Ligation of the alpha2M* signaling receptor regulates synthesis of cytosolic phospholipase A2. 
  • Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes. 
  • Liver cancer: EphrinA2 promotes tumorigenicity through Rac1/Akt/NF-kappaB signaling pathway. 
  • LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling. 
  • LncRNA VINAS regulates atherosclerosis by modulating NF-κB and MAPK signaling. 
  • Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat. 
  • Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin binding. 
  • Loss of MyD88 leads to more aggressive TRAMP prostate cancer and influences tumor infiltrating lymphocytes. 
  • Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome. 
  • Low K+ promotes NF-kappaB/DNA binding in neuronal apoptosis induced by K+ loss. 
  • Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice. 
  • Lysophosphatidic acid promotes survival of androgen-insensitive prostate cancer PC3 cells via activation of NF-kappaB. 
  • MDM2-dependent inhibition of p53 is required for Epstein-Barr virus B-cell growth transformation and infected-cell survival. 
  • MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells. 
  • MYD88 L265P elicits mutation-specific ubiquitination to drive NF-κB activation and lymphomagenesis. 
  • Macrophage activation by gastric fluid suggests MMP involvement in aspiration-induced lung disease. 
  • Maleylated-BSA induces hydrolysis of PIP2, fluxes of Ca2+, NF-kappaB binding, and transcription of the TNF-alpha gene in murine macrophages. 
  • Mathematical modeling of the Phoenix Rising pathway. 
  • Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer. 
  • Mechanisms of activation of the RAW264.7 macrophage cell line by transfected mammalian DNA. 
  • Mechanisms of immune stimulation by bacterial DNA. 
  • Mechanisms of progesterone receptor inhibition of inflammatory responses in cellular models of breast cancer. 
  • Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. 
  • Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death. 
  • Mechanosignaling in bone health, trauma and inflammation. 
  • Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes. 
  • Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis. 
  • Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract. 
  • Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1. 
  • Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death. 
  • Mn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathways. 
  • Modified vaccinia virus Ankara can activate NF-kappaB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication. 
  • Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli. 
  • Modulation of Human Macrophage Responses to Mycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface Modification. 
  • Modulation of pancreatic cancer chemoresistance by inhibition of TAK1. 
  • Molecular diagnosis of Burkitt's lymphoma. 
  • Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer. 
  • Molecular regulation of constitutive expression of interleukin-8 in human pancreatic adenocarcinoma. 
  • Motif module map reveals enforcement of aging by continual NF-kappaB activity. 
  • Mucosal candidiasis elicits NF-κB activation, proinflammatory gene expression and localized neutrophilia in zebrafish. 
  • MxA suppresses TAK1-IKKα/β-NF-κB mediated inflammatory cytokine production to facilitate Mycobacterium tuberculosis infection. 
  • Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma. 
  • Myocardial NF-κB activation is essential for zebrafish heart regeneration. 
  • NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment. 
  • NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle. 
  • NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation. 
  • NF-kappa B and transcriptional control of renal epithelial-inducible nitric oxide synthase. 
  • NF-kappa B as a central mediator in the induction of TGF-beta in monocytes from patients with idiopathic myelofibrosis: an inflammatory response beyond the realm of homeostasis. 
  • NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK. 
  • NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity. 
  • NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. 
  • NF-kappaB cis-acting motifs of the human immunodeficiency virus (HIV) long terminal repeat regulate HIV transcription in human macrophages. 
  • NF-kappaB factors are essential, but not the switch, for pathogen-related induction of the bovine beta-defensin 5-encoding gene in mammary epithelial cells. 
  • NF-kappaB inhibition by an adenovirus expressed aptamer sensitizes TNFalpha-induced apoptosis. 
  • NF-kappaB p65 involves in reperfusion injury and iNOS gene regulation in skeletal muscle. 
  • NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival. 
  • NF-κB signaling pathway and its potential as a target for therapy in lymphoid neoplasms. 
  • NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • NFkappaB expression during cold ischemia correlates with postreperfusion graft function. 
  • NFκB expression is a feature of both activated B-cell-like and germinal center B-cell-like subtypes of diffuse large B-cell lymphoma. 
  • NFκB-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice. 
  • NO inhibits hyperoxia-induced NF-κB activation in neonatal pulmonary microvascular endothelial cells. 
  • Near-Death Cells Cause Chemotherapy-Induced Metastasis via ATF4-Mediated NF-κB Signaling Activation. 
  • Necroptosis-independent signaling by the RIP kinases in inflammation. 
  • Necrosis-dependent and independent signaling of the RIP kinases in inflammation. 
  • Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage. 
  • Nitrosation and oxidation in the regulation of gene expression. 
  • Nitrosative stress-induced apoptosis through inhibition of NF-kappa B. 
  • Non-Cell-Autonomous Activity of the Hemidesmosomal Protein BP180/Collagen XVII in Granulopoiesis in Humanized NC16A Mice. 
  • Non-alcoholic steatohepatitis pathogenesis: role of repair in regulating the disease progression. 
  • Non-erythroid effects of erythropoietin. 
  • Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema. 
  • Novel pathogenic variants in FOXP3 in fetuses with echogenic bowel and skin desquamation identified by ultrasound. 
  • Nox1 NADPH oxidase is necessary for late but not early myocardial ischaemic preconditioning. 
  • Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells. 
  • Nuclear factor kappa B activation is a potential target for preventing pancreatic carcinoma by aspirin. 
  • Nuclear factor kappa B mediates lipopolysaccharide-induced inflammation in the urinary bladder. 
  • Nuclear factor-kappa B regulates pain and COMT expression in a rodent model of inflammation. 
  • Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis. 
  • Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells. 
  • Nuclear factor-kappaB mediates Kupffer cell apoptosis through transcriptional activation of Fas/FasL. 
  • Oncogenic CARD11 mutations in human diffuse large B cell lymphoma. 
  • Ophthalmic Manifestations of ROSAH (Retinal Dystrophy, Optic Nerve Edema, Splenomegaly, Anhidrosis, and Headache) Syndrome, an Inherited NF κB-Mediated Autoinflammatory Disease with Retinal Dystrophy. 
  • Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA. 
  • Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy. 
  • Oxidized low density lipoprotein suppresses activation of NF kappa B in macrophages via a pertussis toxin-sensitive signaling mechanism. 
  • PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and β-catenin. 
  • PSORS2 is due to mutations in CARD14. 
  • Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-κB Signaling. 
  • Peroxide-mediated chromatin remodelling of a nuclear factor kappa B site in the mouse inducible nitric oxide synthase promoter. 
  • Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production. 
  • Phase II trial of curcumin in patients with advanced pancreatic cancer. 
  • Phosphorylation of tumor necrosis factor receptor 1 (p55) protects macrophages from silica-induced apoptosis. 
  • Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. 
  • Picralima nitida seeds suppress PGE2 production by interfering with multiple signalling pathways in IL-1β-stimulated SK-N-SH neuronal cells. 
  • Pimecrolimus enhances TLR2/6-induced expression of antimicrobial peptides in keratinocytes. 
  • Plasticity of renal erythropoietin-producing cells governs fibrosis. 
  • Polarized monocyte response to cytokine stimulation. 
  • Pomegranate inhibits neuroinflammation and amyloidogenesis in IL-1β-stimulated SK-N-SH cells. 
  • Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity. 
  • Potential role of Hedgehog signaling and microRNA-29 in liver fibrosis of IKKβ-deficient mouse. 
  • Potentiation of paclitaxel cytotoxicity in lung and esophageal cancer cells by pharmacologic inhibition of the phosphoinositide 3-kinase/protein kinase B (Akt)-mediated signaling pathway. 
  • Potentiation of the effect of erlotinib by genistein in pancreatic cancer: the role of Akt and nuclear factor-kappaB. 
  • Prevalence and clinical implications of epstein-barr virus infection in de novo diffuse large B-cell lymphoma in Western countries. 
  • Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma. 
  • Prevention of brefeldin A-induced resistance to teniposide by the proteasome inhibitor MG-132: involvement of NF-kappaB activation in drug resistance. 
  • Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. 
  • Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma. 
  • Programmed necrosis in the cross talk of cell death and inflammation. 
  • Prostaglandin A1 inhibits stress-induced NF-kappaB activation and reverses resistance to topoisomerase II inhibitors. 
  • Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network. 
  • Protein Phosphatase 1α and Cofilin Regulate Nuclear Translocation of NF-κB and Promote Expression of the Anti-Inflammatory Cytokine Interleukin-10 by T Cells. 
  • Protein kinase C-zeta is critical in pancreatitis-induced apoptosis of Kupffer cells. 
  • Proteomic dissection of LPS-inducible, PHF8-dependent secretome reveals novel roles of PHF8 in TLR4-induced acute inflammation and T cell proliferation. 
  • Punicalagin inhibits neuroinflammation in LPS-activated rat primary microglia. 
  • RNA Aptamer-targeted Inhibition of NF-κB Suppresses Non-small Cell Lung Cancer Resistance to Doxorubicin. 
  • RNA-Seq and ChIP-Seq reveal SQSTM1/p62 as a key mediator of JunB suppression of NF-κB-dependent inflammation. 
  • RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation. 
  • Re-engineered CD40 receptor enables potent pharmacological activation of dendritic-cell cancer vaccines in vivo. 
  • Reciprocal control of Forkhead box O 3a and c-Myc via the phosphatidylinositol 3-kinase pathway coordinately regulates p27Kip1 levels. 
  • Recombinant adenoviral expression of dominant negative IkappaBalpha protects brain from cerebral ischemic injury. 
  • Reduced mitochondrial activity in colonocytes facilitates AMPKα2-dependent inflammation. 
  • Regulating the regulator: NF-kappaB signaling in heart. 
  • Regulation of Kupffer cell TNF gene expression during experimental acute pancreatitis: the role of p38-MAPK, ERK1/2, SAPK/JNK, and NF-kappaB. 
  • Regulation of NFkappaB in hepatic ischemic preconditioning. 
  • Regulation of chondrocytic gene expression by biomechanical signals. 
  • Regulation of cytosolic phospholipase A2 activity in macrophages stimulated with receptor-recognized forms of alpha 2-macroglobulin: role in mitogenesis and cell proliferation. 
  • Regulation of estrogen receptors and MMP-2 expression by estrogens in human retinal pigment epithelium. 
  • Regulation of human retroviral latency by the NF-kappa B/I kappa B family: inhibition of human immunodeficiency virus replication by I kappa B through a Rev-dependent mechanism. 
  • Regulation of inflammation by β-arrestins: Not just receptor tales. 
  • Regulation of interleukin-8 expression by cellular pH in human pancreatic adenocarcinoma cells. 
  • RelA NF-κB subunit activation as a therapeutic target in diffuse large B-cell lymphoma. 
  • RelB cellular regulation and transcriptional activity are regulated by p100. 
  • Release of nonmuscle myosin II from the cytosolic domain of tumor necrosis factor receptor 2 is required for target gene expression. 
  • Resistance to ErbB2 tyrosine kinase inhibitors in breast cancer is mediated by calcium-dependent activation of RelA. 
  • Resolving postoperative neuroinflammation and cognitive decline. 
  • Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma. 
  • Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain). 
  • Retinoic acid-induced gene-I (RIG-I) associates with nucleotide-binding oligomerization domain-2 (NOD2) to negatively regulate inflammatory signaling. 
  • Reversal of physiological stress-induced resistance to topoisomerase II inhibitors using an inducible phosphorylation site-deficient mutant of I kappa B alpha. 
  • Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO. 
  • Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10. 
  • Role of the autotaxin-lysophosphatidic acid axis in glaucoma, aqueous humor drainage and fibrogenic activity. 
  • S-nitrosylation in the regulation of gene transcription. 
  • S-nitrosylation: physiological regulation of NF-kappaB. 
  • SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells. 
  • SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques. 
  • SMAD3 deficiency promotes vessel wall remodeling, collagen fiber reorganization and leukocyte infiltration in an inflammatory abdominal aortic aneurysm mouse model. 
  • SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. 
  • Scavenger receptor BI attenuates oxidized phospholipid-induced pulmonary inflammation. 
  • Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB. 
  • Self-inflicted DNA double-strand breaks sustain tumorigenicity and stemness of cancer cells. 
  • Sequestration of mitochondrial iron by silica particle initiates a biological effect. 
  • Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes. 
  • Seven-transmembrane receptor signaling through beta-arrestin. 
  • Signaling pathways mediating beta3-adrenergic receptor-induced production of interleukin-6 in adipocytes. 
  • Social history and exposure to pathogen signals modulate social status effects on gene regulation in rhesus macaques. 
  • Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB. 
  • Stable expression of transdominant Rev protein in human T cells inhibits human immunodeficiency virus replication. 
  • Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression. 
  • Stimulating TAM-mediated anti-tumor immunity with mannose-decorated nanoparticles in ovarian cancer. 
  • Stimulation of the α7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice. 
  • Studies on the interaction between TWEAK and the death receptor WSL-1/TRAMP (DR3). 
  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes. 
  • Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor. 
  • Suppression of the NF-κB pathway by diesel exhaust particles impairs human antimycobacterial immunity. 
  • Sustained stress response after oxidative stress in trabecular meshwork cells. 
  • Synergic effect of OP449 and FTY720 on oral squamous cell carcinoma. 
  • TLR agonists regulate PDGF-B production and cell proliferation through TGF-beta/type I IFN crosstalk. 
  • TNFR2 interposes the proliferative and NF-κB-mediated inflammatory response by podocytes to TNF-α. 
  • Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation. 
  • Targeted gene therapy for rat glomerulonephritis using HVJ-immunoliposomes. 
  • Targeted therapy for non-small cell lung cancer. 
  • Targeting High Mobility Group Box-1 (HMGB1) Promotes Cell Death in Myelodysplastic Syndrome. 
  • Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma. 
  • Tepoxalin enhances the activity of an antioxidant, pyrrolidine dithiocarbamate, in attenuating tumor necrosis factor alpha-induced apoptosis in WEHI 164 cells. 
  • The C-terminal domain of A1/Bfl-1 regulates its anti-inflammatory function in human endothelial cells. 
  • The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells. 
  • The Importance of IL-6 in the Development of LAT-Mediated Autoimmunity. 
  • The NF-kappa B inhibitor, tepoxalin, suppresses surface expression of the cell adhesion molecules CD62E, CD11b/CD18 and CD106. 
  • The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells. 
  • The Ubiquitin-Modifying Enzyme A20 Terminates C-Type Lectin Receptor Signals and Is a Suppressor of Host Defense against Systemic Fungal Infection. 
  • The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B. 
  • The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis. 
  • The apolipoprotein E-mimetic peptide COG112 inhibits the inflammatory response to Citrobacter rodentium in colonic epithelial cells by preventing NF-kappaB activation. 
  • The aryl hydrocarbon nuclear translocator alters CD30-mediated NF-kappaB-dependent transcription. 
  • The biology of tobacco and nicotine: bench to bedside. 
  • The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival. 
  • The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis. 
  • The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes. 
  • The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles. 
  • The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB. 
  • The long isoform of cellular FLIP is essential for T lymphocyte proliferation through an NF-kappaB-independent pathway. 
  • The manganese(III) porphyrin MnTnHex-2-PyP5+ modulates intracellular ROS and breast cancer cell migration: Impact on doxorubicin-treated cells. 
  • The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. 
  • The proto-oncogene bcl-3 encodes an I kappa B protein. 
  • The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor beta-dependent apoptosis in breast cancer. 
  • The type III transforming growth factor-beta receptor negatively regulates nuclear factor kappa B signaling through its interaction with beta-arrestin2. 
  • Thymic Epithelial Cells Contribute to Thymopoiesis and T Cell Development. 
  • Time course of LPS-induced gene expression in a mouse model of genitourinary inflammation. 
  • Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells. 
  • Toll-like receptor 4 mediates mitochondrial DNA damage and biogenic responses after heat-inactivated E. coli. 
  • Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells. 
  • Transcription factor NF-kappaB regulates inducible CD83 gene expression in activated T lymphocytes. 
  • Transcription factor decoy for NFkappaB inhibits TNF-alpha-induced cytokine and adhesion molecule expression in vivo. 
  • Transcription of the RelB gene is regulated by NF-kappaB. 
  • Transforming growth factor beta stimulates the human immunodeficiency virus 1 enhancer and requires NF-kappaB activity. 
  • Tumor necrosis factor induces neuroendocrine differentiation in small cell lung cancer cell lines. 
  • Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway. 
  • Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. 
  • Two distinct signalling cascades target the NF-kappaB regulatory factor c-IAP1 for degradation. 
  • Two forms of NF-kappa B1 (p105/p50) in murine macrophages: differential regulation by lipopolysaccharide, interleukin-2, and interferon-gamma. 
  • Tyloxapol inhibits NF-kappa B and cytokine release, scavenges HOCI, and reduces viscosity of cystic fibrosis sputum. 
  • USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis. 
  • Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation. 
  • Unc-13 homolog D mediates an antiviral effect of the chromosome 19 microRNA cluster miR-517a. 
  • Uncoupling of the signaling and caspase-inhibitory properties of X-linked inhibitor of apoptosis. 
  • Unexpected positive control of NFκB and miR-155 by DGKα and ζ ensures effector and memory CD8+ T cell differentiation. 
  • Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc. 
  • Up-regulated expression of extracellular matrix remodeling genes in phagocytically challenged trabecular meshwork cells. 
  • Up-regulation of cyclooxygenase-2 expression and prostaglandin synthesis in endometrial stromal cells by malignant endometrial epithelial cells. A paracrine effect mediated by prostaglandin E2 and nuclear factor-kappa B. 
  • Variation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer. 
  • Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity. 
  • Vibrio vulnificus induces mTOR activation and inflammatory responses in macrophages. 
  • Viral cell death inhibitor MC159 enhances innate immunity against vaccinia virus infection. 
  • Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling. 
  • Vitamin B1 Helps to Limit Mycobacterium tuberculosis Growth via Regulating Innate Immunity in a Peroxisome Proliferator-Activated Receptor-γ-Dependent Manner. 
  • Vitamin E therapy of acute CCl4-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding. 
  • X-linked inhibitor of apoptosis protein mediates tumor cell resistance to antibody-dependent cellular cytotoxicity. 
  • XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype. 
  • XIAP as a ubiquitin ligase in cellular signaling. 
  • XIAP regulates cytosol-specific innate immunity to Listeria infection. 
  • [LMP-420, a new therapeutic approach for cerebral malaria?]. 
  • beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha. 
  • c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis. 
  • c-FLIP protects eosinophils from TNF-α-mediated cell death in vivo. 
  • cDNA expression arrays: the effects of lactacystin in lipopolysaccharide-induced cystitis. 
  • miR-301a as an NF-κB activator in pancreatic cancer cells. 
  • p38α MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions. 
• 

  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Luftig, Micah Alan, Professor of Molecular Genetics and Microbiology, Cell Biology
  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Cell Biology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology