RNA, Antisense
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Subject Areas on Research
- A single stem-loop structure within the HTLV-1 Rex response element is sufficient to mediate Rex activity in vivo.
- Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
- Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells.
- Caenorhabditis elegans beta-G spectrin is dispensable for establishment of epithelial polarity, but essential for muscular and neuronal function.
- Calmodulin is required for cell-cycle progression during G1 and mitosis.
- Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta.
- Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in mice expressing antisense RNA to DNA polymerase zeta.
- Experimental evidence for the secondary structure of the hepatitis delta virus ribozyme.
- Expression of chimeric tRNA-driven antisense transcripts renders NIH 3T3 cells highly resistant to Moloney murine leukemia virus replication.
- High-fidelity mRNA amplification for gene profiling.
- Imprinted expression of the canine IGF2R, in the absence of an anti-sense transcript or promoter methylation.
- Infectious pathogen detection arrays: viral detection in cell lines and postmortem brain tissue.
- Integrated detection of natural antisense transcripts using strand-specific RNA sequencing data.
- Novel retrotransposed imprinted locus identified at human 6p25.
- Novel therapies for pancreatic adenocarcinoma.
- RNA interference: antiviral defense and genetic tool.
- Short-term kinetics of tumor antigen expression in response to vaccination.
- Splicing of an anti-sense Alu sequence generates a coding sequence variant for the alpha-3 subunit of a neuronal acetylcholine receptor.
- Submucosal glands are the predominant site of CFTR expression in the human bronchus.
- The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans.
- Transfection of ovarian cancer cells with tumor necrosis factor-alpha (TNF-alpha) antisense mRNA abolishes the proliferative response to interleukin-1 (IL-1) but not TNF-alpha.
- Up-regulated P21CIP1 expression is part of the regulation quantitatively controlling serum deprivation-induced apoptosis.
- lambda RNA internal standards quantify sensitivity and amplification efficiency of mammalian gene expression profiling.
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Keywords of People
- Bennett, Vann, George B. Geller Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute
- Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology