Neurites

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  Subject Areas on Research

  • 14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening. 
  • A Farnesyltransferase Acts to Inhibit Ectopic Neurite Formation in C. elegans. 
  • A laminin and nerve growth factor-laden three-dimensional scaffold for enhanced neurite extension. 
  • A transcription-dependent switch controls competence of adult neurons for distinct modes of axon growth. 
  • Activated microglia proliferate at neurites of mutant huntingtin-expressing neurons. 
  • Adverse benzo[a]pyrene effects on neurodifferentiation are altered by other neurotoxicant coexposures: interactions with dexamethasone, chlorpyrifos, or nicotine in PC12 cells. 
  • Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures. 
  • Alpha7 nicotinic acetylcholine receptors targeted by cholinergic developmental neurotoxicants: nicotine and chlorpyrifos. 
  • Anisotropic scaffolds facilitate enhanced neurite extension in vitro. 
  • Apolipoprotein E and Alzheimer disease. 
  • Apolipoprotein E and Alzheimer's disease. 
  • Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls. 
  • CS-4,6 is differentially upregulated in glial scar and is a potent inhibitor of neurite extension. 
  • Casein kinase 1 regulates Sprouty2 in FGF-ERK signaling. 
  • Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study. 
  • Concentration-Dependent Dual Role of Thrombin in Protection of Cultured Rat Cortical Neurons. 
  • Cordon-bleu is an actin nucleation factor and controls neuronal morphology. 
  • Denatured muscle as a nerve conduit: a functional, morphologic, and electrophysiologic evaluation. 
  • Distinct electric potentials in soma and neurite membranes. 
  • Distinction between differentiation, cell cycle, and apoptosis signals in PC12 cells by the nerve growth factor mutant delta9/13, which is selective for the p75 neurotrophin receptor. 
  • Does prenatal nicotine exposure sensitize the brain to nicotine-induced neurotoxicity in adolescence? 
  • Dorsal root ganglia neurite extension is inhibited by mechanical and chondroitin sulfate-rich interfaces. 
  • Dynamic microtubules drive circuit rewiring in the absence of neurite remodeling. 
  • ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells. 
  • Expression of alpha(2)-adrenergic receptor subtypes in prenatal rat spinal cord. 
  • Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway. 
  • GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1. 
  • Glial growth factor 2, a soluble neuregulin, directly increases Schwann cell motility and indirectly promotes neurite outgrowth. 
  • Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins. 
  • Hydrogel-based three-dimensional matrix for neural cells. 
  • Hypothesis testing for neural cell growth experiments using a hybrid branching process model. 
  • Induction of neuronal morphology in adrenal chromaffin cells cocultured with denervated Schwann cells. 
  • Interaction of apolipoprotein E with laminin increases neuronal adhesion and alters neurite morphology. 
  • Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos? 
  • L1-dependent neuritogenesis involves ankyrinB that mediates L1-CAM coupling with retrograde actin flow. 
  • Laminin oligopeptide derivatized agarose gels allow three-dimensional neurite extension in vitro. 
  • Localized membrane depolarizations and localized calcium influx during electric field-guided neurite growth. 
  • Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease. 
  • Merosin promotes neurite growth and Schwann cell migration in vitro and nerve regeneration in vivo: evidence using an antibody to merosin, ARM-1. 
  • Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells. 
  • Modulation of Rho GTPase activity alleviates chondroitin sulfate proteoglycan-dependent inhibition of neurite extension. 
  • Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson's Disease Patients. 
  • Neurite outgrowth from progeny of epidermal growth factor-responsive hippocampal stem cells is significantly less robust than from fetal hippocampal cells following grafting onto organotypic hippocampal slice cultures: effect of brain-derived neurotrophic factor. 
  • Neurite outgrowth is enhanced by anti-idiotypic monoclonal antibodies to the ganglioside GM1. 
  • Neuronal activity-regulated gene transcription in synapse development and cognitive function. 
  • Neuronal cell shape and neurite initiation are regulated by the Ndr kinase SAX-1, a member of the Orb6/COT-1/warts serine/threonine kinase family. 
  • Neurotrophin regulation of ionic currents and cell size depends on cell context. 
  • Neurotrophins affect the pattern of DRG neurite growth in a bioassay that presents a choice of CNS and PNS substrates. 
  • Nicotine is a neurotoxin in the adolescent brain: critical periods, patterns of exposure, regional selectivity, and dose thresholds for macromolecular alterations. 
  • Nonenzymatic role of acetylcholinesterase in neuritic sprouting: regional changes in acetylcholinesterase and choline acetyltransferase after neonatal 6-hydroxydopamine lesions. 
  • Novel inhibitory action of tunicamycin homologues suggests a role for dynamic protein fatty acylation in growth cone-mediated neurite extension. 
  • Null mutation of c-fos impairs structural and functional plasticities in the kindling model of epilepsy. 
  • Oxidative stress from diverse developmental neurotoxicants: antioxidants protect against lipid peroxidation without preventing cell loss. 
  • Polylysine-functionalised thermoresponsive chitosan hydrogel for neural tissue engineering. 
  • Protein kinase C delta (PKCdelta) is required for protein tyrosine phosphatase mu (PTPmu)-dependent neurite outgrowth. 
  • Role of fibronectin in topographical guidance of neurite extension on electrospun fibers. 
  • Selective enhancement of axonal branching of cultured dentate gyrus neurons by neurotrophic factors. 
  • Selective inhibitors of the FK506-binding protein 51 by induced fit. 
  • The influence of physical structure and charge on neurite extension in a 3D hydrogel scaffold. 
  • The polarity and magnitude of ambient charge influences three-dimensional neurite extension from DRGs. 
  • The role of aligned polymer fiber-based constructs in the bridging of long peripheral nerve gaps. 
  • Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons. 
  • Whole-brain activity mapping onto a zebrafish brain atlas. 
  • [Potential role of presenilin 1 in regulation of synaptic function]. 
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  Keywords of People

  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Innovation & Entrepreneurship
  • Turner, Dennis Alan, Professor of Neurosurgery, Biomedical Engineering