Pancreaticoduodenectomy

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  Subject Areas on Research

  • A matched case-control study of preoperative biliary drainage in patients with pancreatic adenocarcinoma: routine drainage is not justified. 
  • A standardized care plan is associated with shorter hospital length of stay in patients undergoing pancreaticoduodenectomy. 
  • Aberrant expression of p53, p21, cyclin D1, and Bcl2 and their clinicopathological correlation in ampullary adenocarcinoma. 
  • Adjuvant therapy of pancreatic cancer. 
  • Advances in the diagnosis and treatment of adenocarcinoma of the pancreas. 
  • Benchmarks in Pancreatic Surgery: A Novel Tool for Unbiased Outcome Comparisons. 
  • Biliary self-expandable metal stents do not adversely affect pancreaticoduodenectomy. 
  • Carcinoid of the ampulla of Vater presenting as acute pancreatitis. 
  • Carcinoma of the ampulla of Vater: patterns of failure following resection and benefit of chemoradiotherapy. 
  • Clinicopathologic features and prognosis of duodenal adenocarcinoma and comparison with ampullary and pancreatic ductal adenocarcinoma. 
  • Comment on: Major hepatectomy with or without pancreatoduodenectomy for advanced gallbladder cancer. 
  • Comparison of outcomes and the use of multimodality therapy in young and elderly people undergoing surgical resection of pancreatic cancer. 
  • Comparison of skin closure techniques in patients undergoing open pancreaticoduodenectomy: A single center experience. 
  • Complications of pancreaticoduodenectomy after neoadjuvant chemoradiation in patients with and without preoperative biliary drainage. 
  • Contemporary experience with postpancreatectomy hemorrhage: results of 1,122 patients resected between 2006 and 2011. 
  • Defining a Hospital Volume Threshold for Minimally Invasive Pancreaticoduodenectomy in the United States. 
  • Defining morbidity after pancreaticoduodenectomy: use of a prospective complication grading system. 
  • Defining the learning curve for team-based laparoscopic pancreaticoduodenectomy. 
  • Delayed recovery after pancreaticoduodenectomy: a major factor impairing the delivery of adjuvant therapy? 
  • Detailed Analysis of Margin Positivity and the Site of Local Recurrence After Pancreaticoduodenectomy. 
  • Development of an integrated biospecimen bank and multidisciplinary clinical database for pancreatic cancer. 
  • Diagnostic and therapeutic implications of a novel immunohistochemical panel detecting duodenal mucosal invasion by pancreatic ductal adenocarcinoma. 
  • Does preoperative therapy optimize outcomes in patients with resectable pancreatic cancer? 
  • Does radiologic response correlate to pathologic response in patients undergoing neoadjuvant therapy for borderline resectable pancreatic malignancy? 
  • Downstaging in pancreatic cancer: a matched analysis of patients resected following systemic treatment of initially locally unresectable disease. 
  • Early Recurrence and Omission of Adjuvant Therapy after Pancreaticoduodenectomy Argue against a Surgery-First Approach. 
  • Education and imaging. Hepatobiliary and pancreatic: Recurrent pancreatitis caused by a solid pseudopapillary neoplasm of the pancreas. 
  • Effect of intra-operative fluid volume on peri-operative outcomes after pancreaticoduodenectomy for pancreatic adenocarcinoma. 
  • Effect of neoadjuvant chemoradiation and surgical technique on recurrence of localized pancreatic cancer. 
  • Effect of neoadjuvant chemoradiation on operative mortality and morbidity for pancreaticoduodenectomy. 
  • Electronic synoptic operative reporting: assessing the reliability and completeness of synoptic reports for pancreatic resection. 
  • Empiric nasogastric decompression after pancreaticoduodenectomy is not necessary. 
  • Evaluation of preoperative therapy for pancreatic cancer using a prognostic nomogram. 
  • Extended resection for pancreatic adenocarcinoma. 
  • Failure patterns in resected pancreas adenocarcinoma: lack of predicted benefit to SMAD4 expression. 
  • Feeding jejunostomy during Whipple is associated with increased morbidity. 
  • Feeding jejunostomy tube placement in patients undergoing pancreaticoduodenectomy: an ongoing dilemma. 
  • Frequency and intensity of postoperative surveillance after curative treatment of pancreatic cancer: a cost-effectiveness analysis. 
  • Gallbladder cancer: differences in presentation, surgical treatment, and survival in patients treated at centers in three countries. 
  • Going the Extra Mile: Improved Survival for Pancreatic Cancer Patients Traveling to High-volume Centers. 
  • Hepatic arterial nodal metastases in pancreatic cancer: is this the node of importance? 
  • Histologic grading of the extent of residual carcinoma following neoadjuvant chemoradiation in pancreatic ductal adenocarcinoma: a predictor for patient outcome. 
  • Impact of Angiotensin Receptor Blocker Use on Overall Survival Among Patients Undergoing Resection for Pancreatic Cancer. 
  • Impact of enhanced recovery protocols after pancreatoduodenectomy: meta-analysis. 
  • Impact of extent of surgery on survival in patients with small nonfunctional pancreatic neuroendocrine tumors in the United States. 
  • Impact of obesity and body fat distribution on survival after pancreaticoduodenectomy for pancreatic adenocarcinoma. 
  • Improved overall survival is still observed in patients receiving delayed adjuvant chemotherapy after pancreaticoduodenectomy for pancreatic adenocarcinoma. 
  • Incidence of benign disease in patients that underwent resection for presumed pancreatic cancer diagnosed by endoscopic ultrasonography (EUS) and fine-needle aspiration (FNA). 
  • Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival. 
  • Intraductal papillary neoplasm of the bile duct: a biliary equivalent to intraductal papillary mucinous neoplasm of the pancreas? 
  • Is the therapeutic index better with gemcitabine-based chemoradiation than with 5-fluorouracil-based chemoradiation in locally advanced pancreatic cancer? 
  • Local ampullary resection with careful intraoperative frozen section evaluation for presumed benign ampullary neoplasms. 
  • Major vascular resection as part of pancreaticoduodenectomy for cancer: radiologic, intraoperative, and pathologic analysis. 
  • Maximizing Tumor Control and Limiting Complications With Stereotactic Body Radiation Therapy for Pancreatic Cancer. 
  • Metastatic ampullary adenocarcinoma presenting as a hydrocele: a case report. 
  • Metformin Use Is Associated with Improved Survival in Patients Undergoing Resection for Pancreatic Cancer. 
  • Minimally Invasive Pancreaticoduodenectomy Does Not Improve Use or Time to Initiation of Adjuvant Chemotherapy for Patients With Pancreatic Adenocarcinoma. 
  • Minimally Invasive Surgical Site Infection in Procedure-Targeted ACS NSQIP Pancreaticoduodenectomies. 
  • Minimally Invasive Versus Open Pancreaticoduodenectomy for Cancer: Practice Patterns and Short-term Outcomes Among 7061 Patients. 
  • Morbidity and mortality after pancreaticoduodenectomy in patients with borderline resectable type C clinical classification. 
  • Nationwide trends and outcomes associated with neoadjuvant therapy in pancreatic cancer: An analysis of 18 243 patients. 
  • Neoadjuvant chemoradiation for adenocarcinoma of the pancreas. 
  • Neoadjuvant chemoradiation for adenocarcinoma of the pancreas. 
  • Novel Preoperative Patient-centered Surgical Wellness Program Impacts Length of Stay Following Pancreatectomy. 
  • Outcomes after Pancreatectomy with Routine Pasireotide Use. 
  • Pain management, fluid therapy and thromboprophylaxis after pancreatoduodenectomy: a worldwide survey among surgeons. 
  • Pancreas and liver resection in Jehovah's Witness patients: feasible and safe. 
  • Pancreatic Head Resection Following Roux-en-Y Gastric Bypass: Operative Considerations and Outcomes. 
  • Pancreatic intraepithelial neoplasia and histological changes in non-neoplastic pancreas associated with neoadjuvant therapy in patients with pancreatic ductal adenocarcinoma. 
  • Pancreaticoduodenectomy for the treatment of pancreatic neoplasms in children: A Pediatric Surgical Oncology Research Collaborative study. 
  • Pancreaticoduodenectomy: frequency and outcome of post-operative imaging-guided percutaneous drainage. 
  • Pasireotide for postoperative pancreatic fistula. 
  • Pathologic complete response to neoadjuvant therapy in patients with pancreatic ductal adenocarcinoma is associated with a better prognosis. 
  • Pathologic grade and tumor size are associated with recurrence-free survival in patients with duodenal neuroendocrine tumors. 
  • Patterns of failure after pancreaticoduodenectomy for ampullary carcinoma. 
  • Perineural and intraneural invasion in posttherapy pancreaticoduodenectomy specimens predicts poor prognosis in patients with pancreatic ductal adenocarcinoma. 
  • Perioperative Bundle to Reduce Surgical Site Infection after Pancreaticoduodenectomy: A Prospective Cohort Study. 
  • Perioperative Care Implementation: Evidence-Based Practice for Patients With Pancreaticoduodenectomy Using the Enhanced Recovery After Surgery Guidelines 
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  • Phase I trial evaluating the safety of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer. 
  • Phase II study of bevacizumab with concurrent capecitabine and radiation followed by maintenance gemcitabine and bevacizumab for locally advanced pancreatic cancer: Radiation Therapy Oncology Group RTOG 0411. 
  • Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation. 
  • Portal vein resection during pancreaticoduodenectomy for pancreatic neuroendocrine tumors. An international multicenter comparative study. 
  • Post-Pancreaticoduodenectomy Outcomes and Epidural Analgesia: A 5-year Single-Institution Experience. 
  • Postoperative complications and overall survival after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma. 
  • Pre- and intraoperative variables affecting early outcomes in elderly patients undergoing pancreaticoduodenectomy. 
  • Predictors of Post-Operative Pain Relief in Patients with Chronic Pancreatitis Undergoing the Frey or Whipple Procedure. 
  • Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience. 
  • Preoperative and postoperative chemoradiation strategies in patients treated with pancreaticoduodenectomy for adenocarcinoma of the pancreas. 
  • Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas. 
  • Preoperative chemoradiation for adenocarcinoma of the pancreas: excessive toxicity of prophylactic hepatic irradiation. 
  • Preoperative chemoradiation for patients with pancreatic cancer: toxicity of endobiliary stents. 
  • Preoperative chemoradiation strategies for localized adenocarcinoma of the pancreas. 
  • Preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for adenocarcinoma of the pancreatic head. 
  • Preoperative gemcitabine and cisplatin followed by gemcitabine-based chemoradiation for resectable adenocarcinoma of the pancreatic head. 
  • Preoperative gemcitabine-based chemoradiation for patients with resectable adenocarcinoma of the pancreatic head. 
  • Preoperative predictors for complications after pancreaticoduodenectomy: impact of BMI and body fat distribution. 
  • Presentation and management of gastrointestinal stromal tumors of the duodenum: a multi-institutional analysis. 
  • Prognostic factors in resectable pancreatic cancer: p53 and bcl-2. 
  • Prognostic indicators following curative pancreatoduodenectomy for pancreatic carcinoma: A retrospective multivariate analysis of a single centre experience. 
  • Prospective Randomized Controlled Trial of Liberal Vs Restricted Perioperative Fluid Management in Patients Undergoing Pancreatectomy. 
  • Quality of Life Associated with Open vs Minimally Invasive Pancreaticoduodenectomy: A Prospective Pilot Study. 
  • Rapid-fractionation pre-operative chemoradiation for malignant periampullary neoplasms. 
  • Rapid-fractionation preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for resectable pancreatic adenocarcinoma. 
  • Readmission after pancreatic resection: causes and causality pattern. 
  • Relationship between intraoperative fluid administration and perioperative outcome after pancreaticoduodenectomy: results of a prospective randomized trial of acute normovolemic hemodilution compared with standard intraoperative management. 
  • Renal outcomes following left renal vein harvest for venous reconstruction during pancreas and liver surgery. 
  • Resection margins in carcinoma of the head of the pancreas. Implications for radiation therapy. 
  • Routine Gastric Decompression after Pancreatoduodenectomy: Treating the Surgeon? 
  • Serum CA 19-9 as a marker of resectability and survival in patients with potentially resectable pancreatic cancer treated with neoadjuvant chemoradiation. 
  • Solid pseudopapillary neoplasm of the pancreas: clinicopathologic and survival analyses of 64 cases from a single institution. 
  • Solid pseudopapillary tumors of the pancreas. Clinical features, surgical outcomes, and long-term survival in 45 consecutive patients from a single center. 
  • Spindle cell stromal tumor of the pancreas: treatment by pancreatoduodenectomy. 
  • Surgical Strategy and Outcomes in Duodenal Gastrointestinal Stromal Tumor. 
  • Surgical treatment of resectable and borderline resectable pancreatic cancer: expert consensus statement by Evans et al. 
  • Synchronous resection of esophageal cancer and other organ malignancies: A systematic review. 
  • The "Nouvelle Vague" of surgeons in pancreatic surgery: can they rise to the legacy of current surgeons? 
  • The Cost of Postoperative Pancreatic Fistula Versus the Cost of Pasireotide: Results from a Prospective Randomized Trial. 
  • The expression of PTEN is associated with improved prognosis in patients with ampullary adenocarcinoma after pancreaticoduodenectomy. 
  • The feasibility and safety of immunotherapy with dendritic cells loaded with CEA mRNA following neoadjuvant chemoradiotherapy and resection of pancreatic cancer. 
  • The impact of vascular resection on early postoperative outcomes after pancreaticoduodenectomy: an analysis of the American College of Surgeons National Surgical Quality Improvement Program database. 
  • The influence of total nodes examined, number of positive nodes, and lymph node ratio on survival after surgical resection and adjuvant chemoradiation for pancreatic cancer: a secondary analysis of RTOG 9704. 
  • The need for standardized pathologic staging of pancreaticoduodenectomy specimens. 
  • The safety of a pancreaticoduodenectomy in patients older than 80 years: risk vs. benefits. 
  • The use of pancreatic ductoscopy in the operative management of benign and malignant pancreatic disorders. 
  • Thin-section contrast-enhanced computed tomography accurately predicts the resectability of malignant pancreatic neoplasms. 
  • Timing of elective surgery as a perioperative outcome variable: analysis of pancreaticoduodenectomy. 
  • Total robotic pancreaticoduodenectomy: a systematic review of the literature. 
  • Toxicity and efficacy of concurrent gemcitabine and radiotherapy for locally advanced pancreatic cancer. 
  • Transient Biliary Fistula After Pancreatoduodenectomy Increases Risk of Biliary Anastomotic Stricture. 
  • Treatment sequencing for resectable pancreatic cancer: influence of early metastases and surgical complications on multimodality therapy completion and survival. 
  • Tumor invasion of muscular vessels predicts poor prognosis in patients with pancreatic ductal adenocarcinoma who have received neoadjuvant therapy and pancreaticoduodenectomy. 
  • Two open whipples a day: Excessive or efficient. 
  • Unusual finding in a patient with pancreas divisum and abdominal pain. 
  • Using a modification of the Clavien-Dindo system accounting for readmissions and multiple interventions: defining quality for pancreaticoduodenectomy. 
  • Utility of a prognostic nomogram designed for gastric cancer in predicting outcome of patients with R0 resected duodenal adenocarcinoma. 
  • Variability in blood transfusions after pancreaticoduodenectomy: A national analysis of the University HealthSystem Consortium. 
  • Vascular surgery collaboration during pancreaticoduodenectomy with vascular reconstruction. 
  • WHipple-ABACUS, a simple, validated risk score for 30-day mortality after pancreaticoduodenectomy developed using the ACS-NSQIP database. 
  • Wound classification reporting in HPB surgery: can a single word change public perception of institutional performance? 
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  Keywords of People

  • Abbruzzese, James, D. C. I. Distinguished Professor of Medical Oncology, Medicine, Medical Oncology
  • Jowell, Paul Simon, Professor of Medicine, Medicine, Gastroenterology
  • Knechtle, Stuart Johnston, William R. Kenan, Jr. Distinguished Professor, Medicine, Nephrology
  • McCall, Shannon Jones, Associate Professor of Pathology, Pathology
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Zafar, Syed Yousuf, Adjunct Professor in the Department of Medicine, Duke Science & Society