Aphidicolin

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  Subject Areas on Research

  • Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14.2. 
  • Enhancement of melphalan activity by inhibition of DNA polymerase-alpha and DNA polymerase-beta. 
  • Human mismatch repair: reconstitution of a nick-directed bidirectional reaction. 
  • Induction of the human heat shock promoter HSP70B by nutritional stress: implications for cancer gene therapy. 
  • Initial amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of embryonic duck hepatocytes is increased by cell cycle progression. 
  • Nucleo-cytoplasmic interactions that control nuclear envelope breakdown and entry into mitosis in the sea urchin zygote. 
  • Nucleotide excision repair functions in the removal of chromium-induced DNA damage in mammalian cells. 
  • Pentoxifylline and other methyl xanthines inhibit interleukin-2 receptor expression in human lymphocytes. 
  • Requirement of the prolyl isomerase Pin1 for the replication checkpoint. 
  • Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. 
  • The human oncoprotein and chromatin architectural factor DEK counteracts DNA replication stress. 
  • The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells. 
  • The protein synthetic surge in response to mitogen triggers high glycolytic enzyme levels in human lymphocytes and occurs prior to DNA synthesis.